Published in Circulation on February 16, 2009
Inflammation and the Metabolic Syndrome in Humans (LPS) | NCT00954824
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages. Arterioscler Thromb Vasc Biol (2010) 3.20
HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol (2011) 2.60
Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes (2009) 2.27
High-density lipoprotein heterogeneity and function in reverse cholesterol transport. Curr Opin Lipidol (2010) 2.23
MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest (2012) 1.77
Cholesterol, inflammation and innate immunity. Nat Rev Immunol (2015) 1.72
High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler Thromb Vasc Biol (2012) 1.70
Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey. Drug Des Devel Ther (2011) 1.68
"Gum bug, leave my heart alone!"--epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis. J Dent Res (2010) 1.61
A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial. J Transl Med (2012) 1.59
Uremia alters HDL composition and function. J Am Soc Nephrol (2011) 1.55
Modification of high density lipoprotein by myeloperoxidase generates a pro-inflammatory particle. J Biol Chem (2009) 1.51
Future therapeutic directions in reverse cholesterol transport. Curr Atheroscler Rep (2010) 1.46
ABC transporters, atherosclerosis and inflammation. Atherosclerosis (2010) 1.41
Cholesterol efflux by high density lipoproteins is impaired in patients with active rheumatoid arthritis. Ann Rheum Dis (2012) 1.36
Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2). J Lipid Res (2010) 1.35
Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia. Am J Hum Biol (2010) 1.30
Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis. Atherosclerosis (2012) 1.29
Molecular mechanisms of vascular effects of High-density lipoprotein: alterations in cardiovascular disease. EMBO Mol Med (2012) 1.26
Humans with atherosclerosis have impaired ABCA1 cholesterol efflux and enhanced high-density lipoprotein oxidation by myeloperoxidase. Circ Res (2014) 1.21
Adipocyte modulation of high-density lipoprotein cholesterol. Circulation (2010) 1.21
Inflammation modulates human HDL composition and function in vivo. Atherosclerosis (2012) 1.18
Dysfunctional HDL as a diagnostic and therapeutic target. Arterioscler Thromb Vasc Biol (2009) 1.17
The acute phase response inhibits reverse cholesterol transport. J Lipid Res (2010) 1.14
Psoriasis alters HDL composition and cholesterol efflux capacity. J Lipid Res (2012) 1.11
Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol (2015) 1.11
Evaluating the impact of sequencing depth on transcriptome profiling in human adipose. PLoS One (2013) 1.11
Race and gender variation in response to evoked inflammation. J Transl Med (2013) 1.10
New insights into the mechanism of low high-density lipoprotein cholesterol in obesity. Lipids Health Dis (2011) 1.10
ATP-binding membrane cassette transporter A1 (ABCA1): a possible link between inflammation and reverse cholesterol transport. Mol Med (2010) 1.10
Transcriptomic signature of Leishmania infected mice macrophages: a metabolic point of view. PLoS Negl Trop Dis (2012) 1.09
Review of hyperuricemia as new marker for metabolic syndrome. ISRN Rheumatol (2014) 1.08
Crosstalk between reverse cholesterol transport and innate immunity. Trends Endocrinol Metab (2012) 1.04
Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport. J Lipid Res (2011) 1.04
Macrophage Phenotype and Function in Different Stages of Atherosclerosis. Circ Res (2016) 1.03
Friend Turns Foe: Transformation of Anti-Inflammatory HDL to Proinflammatory HDL during Acute-Phase Response. Cholesterol (2010) 1.02
Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation. Cell Metab (2010) 1.01
Inflammation predicts changes in high-density lipoprotein particles and apolipoprotein A1 following initiation of antiretroviral therapy. AIDS (2011) 1.01
High-density lipoprotein and the acute phase response. Curr Opin Endocrinol Diabetes Obes (2010) 1.00
Comparison of inflammation, arterial stiffness and traditional cardiovascular risk factors between rheumatoid arthritis and inflammatory bowel disease. J Inflamm (Lond) (2014) 1.00
Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis. Toxicol Sci (2012) 0.99
Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease. Circ Res (2015) 0.98
Apolipoprotein A-I and its mimetics for the treatment of atherosclerosis. Curr Opin Investig Drugs (2010) 0.95
HDL proteome in hemodialysis patients: a quantitative nanoflow liquid chromatography-tandem mass spectrometry approach. PLoS One (2012) 0.95
Impact of serum amyloid A on high density lipoprotein composition and levels. J Lipid Res (2010) 0.95
ATP-binding cassette transporter G1 deficiency dysregulates host defense in the lung. Am J Respir Crit Care Med (2010) 0.95
Myeloperoxidase, inflammation, and dysfunctional high-density lipoprotein. J Clin Lipidol (2010) 0.94
Molecular sources of residual cardiovascular risk, clinical signals, and innovative solutions: relationship with subclinical disease, undertreatment, and poor adherence: implications of new evidence upon optimizing cardiovascular patient outcomes. Vasc Health Risk Manag (2013) 0.94
Autoimmune-mediated reduction of high-density lipoprotein-cholesterol and paraoxonase 1 activity in systemic lupus erythematosus-prone gld mice. Arthritis Rheum (2011) 0.94
Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol. Adv Nutr (2011) 0.93
HDL dysfunction in diabetes: causes and possible treatments. Expert Rev Cardiovasc Ther (2012) 0.92
Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol Nutr Food Res (2013) 0.92
Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia. PLoS One (2012) 0.91
APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage. Neurol Genet (2016) 0.91
Deficiency of endogenous acute phase serum amyloid A does not affect atherosclerotic lesions in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2013) 0.91
Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity. J Lipid Res (2015) 0.90
Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α. Mediators Inflamm (2013) 0.90
Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies. Nutr Metab (Lond) (2012) 0.90
Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway. J Proteomics (2011) 0.90
Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases. Arterioscler Thromb Vasc Biol (2014) 0.90
Acute coronary syndrome remodels the protein cargo and functions of high-density lipoprotein subfractions. PLoS One (2014) 0.88
Human experimental endotoxemia in modeling the pathophysiology, genomics, and therapeutics of innate immunity in complex cardiometabolic diseases. Arterioscler Thromb Vasc Biol (2014) 0.88
Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis. J Transl Med (2013) 0.88
Systematic Review of Metabolic Syndrome Biomarkers: A Panel for Early Detection, Management, and Risk Stratification in the West Virginian Population. Int J Med Sci (2016) 0.88
ATP binding cassette G1-dependent cholesterol efflux during inflammation. J Lipid Res (2010) 0.87
Antagonism of betulinic acid on LPS-mediated inhibition of ABCA1 and cholesterol efflux through inhibiting nuclear factor-kappaB signaling pathway and miR-33 expression. PLoS One (2013) 0.87
HDL-apoA-I exchange: rapid detection and association with atherosclerosis. PLoS One (2013) 0.86
An agomir of miR-144-3p accelerates plaque formation through impairing reverse cholesterol transport and promoting pro-inflammatory cytokine production. PLoS One (2014) 0.86
Adipose modulation of high-density lipoprotein cholesterol: implications for obesity, high-density lipoprotein metabolism, and cardiovascular disease. Circulation (2011) 0.85
The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A. J Lipids (2013) 0.85
Apolipoprotein A-I inhibits LPS-induced atherosclerosis in ApoE(-/-) mice possibly via activated STAT3-mediated upregulation of tristetraprolin. Acta Pharmacol Sin (2013) 0.84
Role of HDL in cholesteryl ester metabolism of lipopolysaccharide-activated P388D1 macrophages. J Lipid Res (2013) 0.84
High density lipoproteins and atherosclerosis: emerging aspects. J Geriatr Cardiol (2012) 0.83
IRAK1 mediates TLR4-induced ABCA1 downregulation and lipid accumulation in VSMCs. Cell Death Dis (2015) 0.83
Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice. PLoS One (2015) 0.83
Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter. Atherosclerosis (2011) 0.83
High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection. Open Forum Infect Dis (2014) 0.82
Inflammation-induced foam cell formation in chronic inflammatory disease. Immunol Cell Biol (2015) 0.82
Aortic vascular inflammation in psoriasis is associated with HDL particle size and concentration: a pilot study. Am J Cardiovasc Dis (2012) 0.81
Cardiovascular disease and rheumatoid arthritis: an update. Curr Rheumatol Rep (2012) 0.81
Subacute decline in serum lipids precedes the occurrence of primary intracerebral hemorrhage. Neurology (2016) 0.80
Physiological Differences Across Populations Reflecting Early Life and Later Life Nutritional Status and Later Life Risk for Chronic Disease. J Popul Ageing (2015) 0.80
Deficiency of glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice. Mol Med (2012) 0.80
Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study. Int J Mol Med (2015) 0.79
Adipose tissue-derived human serum amyloid a does not affect atherosclerotic lesion area in hSAA1+/-/ApoE-/- mice. PLoS One (2014) 0.79
Peroxisome Proliferator-Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia. J Am Heart Assoc (2012) 0.79
Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. J Cell Mol Med (2016) 0.78
High-density lipoprotein cholesterol function improves after successful treatment of psoriasis: a step forward in the right direction. J Invest Dermatol (2014) 0.78
Plasma cholesterol efflux capacity from human THP-1 macrophages is reduced in HIV-infected patients: impact of HAART. J Lipid Res (2015) 0.78
In Vivo Inflammation Does Not Impair ABCA1-Mediated Cholesterol Efflux Capacity of HDL. Cholesterol (2012) 0.78
Endothelial lipase and reverse cholesterol transport in type 2 diabetes mellitus. J Diabetes Investig (2010) 0.78
Increased inflammatory markers with altered antioxidant status persist after clinical recovery from severe sepsis: a correlation with low HDL cholesterol and albumin. Clin Exp Med (2015) 0.78
Extra Virgin Olive Oil Polyphenols Promote Cholesterol Efflux and Improve HDL Functionality. Evid Based Complement Alternat Med (2015) 0.78
Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2016) 0.77
Lipoprotein(a) and Arterial Stiffness Parameters. Pulse (Basel) (2015) 0.77
The interleukin-6 gene promoter polymorphism -174 and atherosclerotic events in overweight transplanted patients. J Transplant (2011) 0.77
The Impact of Intramammary Escherichia coli Challenge on Liver and Mammary Transcriptome and Cross-Talk in Dairy Cows during Early Lactation Using RNAseq. PLoS One (2016) 0.77
Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis. Atherosclerosis (2015) 0.76
Metabolic syndrome in premenopausal and postmenopausal women with type 2 diabetes: loss of protective effects of premenopausal status. J Diabetes Metab Disord (2014) 0.76
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest (2007) 5.38
Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo. J Clin Invest (2007) 4.20
Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis. Am J Gastroenterol (2008) 4.01
Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice. Arterioscler Thromb Vasc Biol (2002) 3.51
Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation (2006) 3.49
Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation (2003) 3.24
Adiponectin and coronary heart disease: a prospective study and meta-analysis. Circulation (2006) 2.89
Innate immunity modulates adipokines in humans. J Clin Endocrinol Metab (2007) 2.48
Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest (2005) 2.47
The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res (2007) 2.38
Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport. Circulation (2007) 1.93
CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. J Am Coll Cardiol (2007) 1.87
Association between elevated liver enzymes and C-reactive protein: possible hepatic contribution to systemic inflammation in the metabolic syndrome. Arterioscler Thromb Vasc Biol (2004) 1.72
Molecular regulation of macrophage reverse cholesterol transport. Curr Opin Cardiol (2007) 1.70
Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation. Circ Res (2005) 1.66
The paradox of dysfunctional high-density lipoprotein. Curr Opin Lipidol (2007) 1.63
Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages. Curr Opin Lipidol (2006) 1.59
Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors. J Lipid Res (2008) 1.58
Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I. J Biol Chem (2005) 1.55
Lipoproteins, not lipopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed Brucella abortus. J Immunol (2004) 1.52
Formation of dysfunctional high-density lipoprotein by myeloperoxidase. Trends Cardiovasc Med (2005) 1.47
HDL cholesterol transport during inflammation. Curr Opin Lipidol (2007) 1.45
Regulation of reverse cholesterol transport and clinical implications. Am J Cardiol (2003) 1.44
A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers. J Lipid Res (2003) 1.44
Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells. Infect Immun (2002) 1.40
Role of serum amyloid A during metabolism of acute-phase HDL by macrophages. Arterioscler Thromb Vasc Biol (2000) 1.40
Apolipoproteins modulate the inflammatory response to lipopolysaccharide. J Endotoxin Res (2005) 1.39
Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice. Endocrinology (1993) 1.37
Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities. J Biol Chem (2005) 1.33
Endothelial lipase is increased in vivo by inflammation in humans. Circulation (2008) 1.27
Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. J Lipid Res (2003) 1.27
Missense mutations in ABCG5 and ABCG8 disrupt heterodimerization and trafficking. J Biol Chem (2004) 1.20
Endotoxin, TNF, and IL-1 decrease cholesterol 7 alpha-hydroxylase mRNA levels and activity. J Lipid Res (1996) 1.19
Endothelial lipase is associated with inflammation in humans. J Lipid Res (2006) 1.12
HDL content and composition in acute phase response in three species: triglyceride enrichment of HDL a factor in its decrease. J Lipid Res (1996) 1.11
Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis. Biochim Biophys Acta (2007) 1.09
HDL modification by secretory phospholipase A(2) promotes scavenger receptor class B type I interaction and accelerates HDL catabolism. J Lipid Res (2000) 1.08
Inflammation stimulates the expression of PCSK9. Biochem Biophys Res Commun (2008) 1.02
Comparative analysis of lipid composition of normal and acute-phase high density lipoproteins. J Lipid Res (2000) 1.02
Endotoxin and interleukin-1 decrease hepatic lipase mRNA levels. Atherosclerosis (1999) 1.02
Lipoproteins are substrates for human secretory group IIA phospholipase A2: preferential hydrolysis of acute phase HDL. J Lipid Res (1998) 1.01
Induction of cellular cholesterol efflux to lipid-free apolipoprotein A-I by cAMP. Biochim Biophys Acta (1999) 1.01
Cholesterol efflux by acute-phase high density lipoprotein: role of lecithin: cholesterol acyltransferase. J Lipid Res (2001) 0.97
SR-BI- and ABCA1-mediated cholesterol efflux to serum from patients with Alagille syndrome. J Lipid Res (2004) 0.95
Precipitation of plasma lipoproteins by PEG-6000 and its evaluation with electrophoresis and ultracentrifugation. Scand J Clin Lab Invest (1976) 0.94
Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines. J Lipid Res (2001) 0.94
Effects of endotoxin on lipid metabolism. Biochem Soc Trans (1995) 0.90
Modifying the anti-inflammatory effects of high-density lipoprotein. Curr Atheroscler Rep (2007) 0.86
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N Engl J Med (2011) 13.55
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet (2009) 6.83
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet (2008) 6.72
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet (2007) 5.88
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet (2010) 5.31
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo. J Clin Invest (2007) 4.20
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis. J Lipid Res (2008) 3.71
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation (2012) 3.38
Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation (2005) 3.25
Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation (2003) 3.24
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages. Arterioscler Thromb Vasc Biol (2010) 3.20
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A (2006) 3.00
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nat Genet (2009) 2.85
Importance of different pathways of cellular cholesterol efflux. Arterioscler Thromb Vasc Biol (2003) 2.70
Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339. J Lipid Res (2005) 2.61
Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles. J Biol Chem (2007) 2.53
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
An inflammatory cascade leading to hyperresistinemia in humans. PLoS Med (2004) 2.51
Innate immunity modulates adipokines in humans. J Clin Endocrinol Metab (2007) 2.48
Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest (2005) 2.47
Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease. J Am Coll Cardiol (2008) 2.42
The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res (2007) 2.38
Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes (2009) 2.27
Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study. Am J Kidney Dis (2011) 2.25
Genetically determined height and coronary artery disease. N Engl J Med (2015) 2.24
The DGA1 gene determines a second triglyceride synthetic pathway in yeast. J Biol Chem (2001) 2.22
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet (2009) 2.09
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport. Circulation (2007) 1.93
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92
CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. J Am Coll Cardiol (2007) 1.87
Strong synaptic transmission impact by copy number variations in schizophrenia. Proc Natl Acad Sci U S A (2010) 1.85
Hypercholesterolemia suppresses inwardly rectifying K+ channels in aortic endothelium in vitro and in vivo. Circ Res (2006) 1.85
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest (2009) 1.83
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux. J Lipid Res (2005) 1.83
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nat Genet (2010) 1.79
Association of lower plasma fetuin-a levels with peripheral arterial disease in type 2 diabetes. Diabetes Care (2009) 1.75
Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I. J Lipid Res (2006) 1.73
Cholesterol depletion increases membrane stiffness of aortic endothelial cells. Biophys J (2004) 1.71
Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. Arterioscler Thromb Vasc Biol (2010) 1.69
Hepatic proprotein convertases modulate HDL metabolism. Cell Metab (2007) 1.68
Fibroblast growth factor 23 is not associated with and does not induce arterial calcification. Kidney Int (2013) 1.66
Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation. Circ Res (2005) 1.66
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet (2011) 1.60
Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway. J Biol Chem (2009) 1.60
A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial. J Transl Med (2012) 1.59
Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J Biol Chem (2003) 1.57
Utility and barriers to performance of the ankle-brachial index in primary care practice. Vasc Med (2004) 1.57
Cholesterol sensitivity and lipid raft targeting of Kir2.1 channels. Biophys J (2004) 1.56
A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock. Am J Respir Crit Care Med (2014) 1.53
Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol. Biophys J (2002) 1.53
Adipokines, insulin resistance, and coronary artery calcification. J Am Coll Cardiol (2008) 1.53
Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles. J Biol Chem (2003) 1.53
Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis. PLoS Med (2005) 1.52
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium. Am J Kidney Dis (2013) 1.52
ABCA1-induced cell surface binding sites for ApoA-I. Arterioscler Thromb Vasc Biol (2007) 1.52
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke (2013) 1.51
Probucol inhibits ABCA1-mediated cellular lipid efflux. Arterioscler Thromb Vasc Biol (2004) 1.46
A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol. J Lipid Res (2011) 1.45
Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux. J Lipid Res (2008) 1.45
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol (2014) 1.45
Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes (2011) 1.44