Published in Can J Microbiol on February 01, 2009
Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med (2009) 39.97
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med (2011) 23.50
Genetics of gene expression and its effect on disease. Nature (2008) 21.35
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
Variations in DNA elucidate molecular networks that cause disease. Nature (2008) 12.04
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet (2005) 11.40
Apixaban in patients with atrial fibrillation. N Engl J Med (2011) 9.97
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol (2009) 9.25
Dronedarone in high-risk permanent atrial fibrillation. N Engl J Med (2011) 8.93
Epidemiology of human infections with avian influenza A(H7N9) virus in China. N Engl J Med (2013) 7.52
Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J Neurosci (2010) 6.44
Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis. BMJ (2012) 6.39
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell (2007) 5.67
Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med (2009) 4.83
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol (2009) 4.49
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell (2013) 4.45
Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity. Nat Genet (2010) 4.35
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol (2009) 4.11
Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma. Acta Neuropathol (2009) 3.97
Gradient-index meta-surfaces as a bridge linking propagating waves and surface waves. Nat Mater (2012) 3.42
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A (2009) 3.39
Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A (2013) 3.25
Bortezomib-based therapy for newly diagnosed mantle-cell lymphoma. N Engl J Med (2015) 3.18
Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. JAMA (2007) 3.09
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nat Genet (2009) 2.97
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans. DNA Res (2004) 2.95
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nat Med (2008) 2.85
BioMagResBank database with sets of experimental NMR constraints corresponding to the structures of over 1400 biomolecules deposited in the Protein Data Bank. J Biomol NMR (2003) 2.74
The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study. Circulation (2013) 2.64
China's facility-based birth strategy and neonatal mortality: a population-based epidemiological study. Lancet (2011) 2.64
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. Genomics (2005) 2.61
QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations. Bioinformatics (2008) 2.57
CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae. Mol Microbiol (2005) 2.56
Non-continuous versus continuous wound drainage after total knee arthroplasty: a meta-analysis. Int Orthop (2013) 2.53
High-efficiency broadband anomalous reflection by gradient meta-surfaces. Nano Lett (2012) 2.53
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res (2010) 2.52
Dabigatran versus warfarin: effects on ischemic and hemorrhagic strokes and bleeding in Asians and non-Asians with atrial fibrillation. Stroke (2013) 2.52
Potential savings from greater use of $4 generic drugs. Arch Intern Med (2011) 2.48
A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One (2007) 2.47
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients. Proc Natl Acad Sci U S A (2003) 2.29
Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One (2008) 2.28
Catalytic carbene insertion into C-H bonds. Chem Rev (2010) 2.27
Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics (2007) 2.27
Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis. Proc Natl Acad Sci U S A (2012) 2.22
Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol (2005) 2.21
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nat Methods (2010) 2.14
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat Struct Mol Biol (2013) 2.14
Detection of minor drug-resistant populations by parallel allele-specific sequencing. Nat Methods (2007) 2.09
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus. J Bacteriol (2004) 2.04
Nuclear export and retention signals in the RS domain of SR proteins. Mol Cell Biol (2002) 2.04
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem (2006) 2.00
Novel plasmid and its variant harboring both a bla(NDM-1) gene and type IV secretion system in clinical isolates of Acinetobacter lwoffii. Antimicrob Agents Chemother (2012) 1.97
Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science (2011) 1.97
Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance. Nat Genet (2013) 1.95
BOLD study of stimulation-induced neural activity and resting-state connectivity in medetomidine-sedated rat. Neuroimage (2007) 1.91
Risk factors for severe illness with 2009 pandemic influenza A (H1N1) virus infection in China. Clin Infect Dis (2011) 1.87
Metabolism of bile salts in mice influences spore germination in Clostridium difficile. PLoS One (2010) 1.87
Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats. PLoS One (2008) 1.86
High-efficiency broadband meta-hologram with polarization-controlled dual images. Nano Lett (2013) 1.85
Disentangling molecular relationships with a causal inference test. BMC Genet (2009) 1.84
A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol (2008) 1.83
Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. PLoS Genet (2010) 1.83
Genetic and phenotypic diversity of quorum-sensing systems in clinical and environmental isolates of Vibrio cholerae. Infect Immun (2006) 1.82
Cooperative astrocyte and dendritic spine dynamics at hippocampal excitatory synapses. J Neurosci (2006) 1.79
A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing. Proc Natl Acad Sci U S A (2006) 1.78
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease. Genome Biol (2009) 1.77
Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Mol Cancer Res (2011) 1.76
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res (2011) 1.71
Human influenza A (H5N1) cases, urban areas of People's Republic of China, 2005-2006. Emerg Infect Dis (2007) 1.71
Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem (2002) 1.70
Long-range polony haplotyping of individual human chromosome molecules. Nat Genet (2006) 1.69
Agrobacterium bioassay strain for ultrasensitive detection of N-acylhomoserine lactone-type quorum-sensing molecules: detection of autoinducers in Mesorhizobium huakuii. Appl Environ Microbiol (2003) 1.69
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. J Virol (2014) 1.67
A Bayesian partition method for detecting pleiotropic and epistatic eQTL modules. PLoS Comput Biol (2010) 1.66
PML nuclear bodies and apoptosis. Oncogene (2004) 1.66
Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun (2013) 1.65
Genotyping and phylogenetic analysis of Yersinia pestis by MLVA: insights into the worldwide expansion of Central Asia plague foci. PLoS One (2009) 1.65
Mucosal penetration primes Vibrio cholerae for host colonization by repressing quorum sensing. Proc Natl Acad Sci U S A (2008) 1.63
Transcatheter closure of perimembranous ventricular septal defect in children: safety and efficiency with symmetric and asymmetric occluders. Catheter Cardiovasc Interv (2010) 1.61
MicroRNAs: novel regulators during the immune response. J Cell Physiol (2009) 1.59
Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis. Plant J (2007) 1.58
Phylogenetic analysis of porcine epidemic diarrhea virus field strains prevailing recently in China. Arch Virol (2012) 1.57
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Surface-plasmon-enhanced GaN-LED based on a multilayered M-shaped nano-grating. Opt Express (2013) 1.56
Bile acids stimulate biofilm formation in Vibrio cholerae. Mol Microbiol (2006) 1.56