Published in Annu Rev Immunol on January 01, 2009
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Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev Cell (2013) 1.04
Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation. Proc Natl Acad Sci U S A (2013) 1.03
The diverse functions of Src family kinases in macrophages. Front Biosci (2008) 1.01
B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice. Proc Natl Acad Sci U S A (2011) 1.01
An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. J Biol Chem (2010) 1.00
B cell-specific loss of Lyn kinase leads to autoimmunity. J Immunol (2013) 1.00
Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases. J Immunol (2005) 0.99
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model. Clin Cancer Res (2009) 0.98
The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation. J Immunol (2005) 0.98
Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa. J Leukoc Biol (2011) 0.97
The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4. Biochem Pharmacol (2005) 0.97
Increased expression of genes linked to FcepsilonRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells. J Immunol (2005) 0.96
Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans. Anesth Analg (2012) 0.95
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood (2013) 0.95
The Src kinase Lyn is a negative regulator of mast cell proliferation. J Leukoc Biol (2003) 0.94
Pyk2 is required for neutrophil degranulation and host defense responses to bacterial infection. J Immunol (2010) 0.94
Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn. J Immunol (2007) 0.93
Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement. J Cell Physiol (2003) 0.92
Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice. J Immunol (2003) 0.92
The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells. J Immunol (2011) 0.91
Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. J Immunol (2008) 0.91
The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina. Infect Immun (2009) 0.88
c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration. FEBS Lett (2010) 0.87
Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement. J Cell Sci (2012) 0.87
Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus. Immunity (2011) 0.87
Generation of a novel system for studying spleen tyrosine kinase function in macrophages and B cells. J Immunol (2009) 0.85
Fgr deficiency results in defective eosinophil recruitment to the lung during allergic airway inflammation. J Immunol (2002) 0.85
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase. J Leukoc Biol (2008) 0.84
Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation. J Immunol (2013) 0.84
Leukocyte adhesion deficiency syndrome: a controversy solved. Immunol Cell Biol (2009) 0.83
The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization. Exp Cell Res (2005) 0.82
Dual function for the adaptor MIST in IFN-gamma production by NK and CD4+NKT cells regulated by the Src kinase Fgr. Blood (2006) 0.81
Expression of the TEL-Syk fusion protein in hematopoietic stem cells leads to rapidly fatal myelofibrosis in mice. PLoS One (2013) 0.80