Published in Antioxid Redox Signal on October 01, 2009
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov (2011) 3.08
NADPH oxidases: functions and pathologies in the vasculature. Arterioscler Thromb Vasc Biol (2009) 2.83
Regulation of coronary arterial BK channels by caveolae-mediated angiotensin II signaling in diabetes mellitus. Circ Res (2010) 1.26
Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research. Antioxid Redox Signal (2013) 1.14
NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arterioscler Thromb Vasc Biol (2014) 0.98
NADPH oxidases: molecular understanding finally reaching the clinical level? Antioxid Redox Signal (2009) 0.93
Effects of angiotensin II on the cerebral circulation: role of oxidative stress. Front Physiol (2013) 0.88
NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? Clin Sci (Lond) (2016) 0.82
Activation of NADPH oxidase 1 increases intracellular calcium and migration of smooth muscle cells. Hypertension (2011) 0.82
Enzymatic regulation and functional relevance of NOX5. Curr Pharm Des (2015) 0.78
Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype. Proc Natl Acad Sci U S A (2016) 0.75
The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side. Int J Mol Sci (2017) 0.75
Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK Channels. Front Physiol (2017) 0.75
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J (2007) 3.88
Ageing and infection. Lancet Infect Dis (2002) 3.79
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res Brain Res Rev (2005) 2.78
HIV-1 egress is gated through late endosomal membranes. Traffic (2003) 2.66
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J Biol Chem (2002) 2.41
Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1. J Cell Biol (2006) 2.38
NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. Mol Cell Biol (2004) 2.38
NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal (2009) 2.38
NOX3, a superoxide-generating NADPH oxidase of the inner ear. J Biol Chem (2004) 2.36
Pneumonia in the very old. Lancet Infect Dis (2004) 2.19
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol (2012) 2.17
Decreased blood pressure in NOX1-deficient mice. FEBS Lett (2005) 2.10
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol (2009) 2.01
NOX enzymes as novel targets for drug development. Semin Immunopathol (2008) 1.90
Neonatal diabetes mellitus: chromosomal analysis in transient and permanent cases. J Pediatr (2002) 1.90
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5). J Biol Chem (2004) 1.86
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal (2009) 1.80
A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxid Redox Signal (2011) 1.79
The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation. Mol Biol Cell (2006) 1.76
A Sox1 to Pax6 switch drives neuroectoderm to radial glia progression during differentiation of mouse embryonic stem cells. Stem Cells (2009) 1.71
NOX family NADPH oxidases: not just in mammals. Biochimie (2007) 1.68
Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2007) 1.65
Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. J Biol Chem (2002) 1.63
Does dementia predict adverse hospitalization outcomes? A prospective study in aged inpatients. Int J Geriatr Psychiatry (2009) 1.62
PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis. Mol Biol Cell (2003) 1.62
Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PLoS One (2010) 1.54
High-density lipoprotein administration attenuates liver proinflammatory response, restores liver endothelial nitric oxide synthase activity, and lowers portal pressure in cirrhotic rats. Hepatology (2007) 1.50
The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms. Hepatology (2007) 1.50
Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors. Stem Cells (2005) 1.48
Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes. Hepatology (2009) 1.45
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C. J Pathol (2010) 1.41
The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity. J Biol Chem (2009) 1.41
Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability. J Biol Chem (2004) 1.41
Novel splice-site mutation in ATP8B1 results in atypical progressive familial intrahepatic cholestasis type 1. J Gastroenterol Hepatol (2013) 1.38
Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase. Semin Immunopathol (2008) 1.37
Non-genomic loss of PTEN function in cancer: not in my genes. Trends Pharmacol Sci (2011) 1.36
Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways. J Immunol (2006) 1.35
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci (2008) 1.34
Acute liver cell damage in patients with anorexia nervosa: a possible role of starvation-induced hepatocyte autophagy. Gastroenterology (2008) 1.34
Demented versus non-demented very old inpatients: the same comorbidities but poorer functional and nutritional status. Age Ageing (2007) 1.32
Proteomics analysis of insulin secretory granules. Mol Cell Proteomics (2007) 1.31
NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice. Am J Respir Crit Care Med (2009) 1.30
NOX1 deficiency protects from aortic dissection in response to angiotensin II. Hypertension (2007) 1.29
Aging and infectious diseases in the developing world. Clin Infect Dis (2004) 1.29
Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia. J Immunol (2005) 1.27
PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism. Gastroenterology (2007) 1.26
NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon. Mol Cell Biol (2010) 1.25
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice. Nat Commun (2012) 1.25
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. PLoS One (2011) 1.24
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism. PLoS One (2011) 1.22
NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes? Biochem Soc Trans (2008) 1.20
A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice. Environ Health Perspect (2007) 1.19
The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells. J Biol Chem (2003) 1.18
Phagocyte NADPH oxidase, chronic granulomatous disease and mycobacterial infections. Cell Microbiol (2014) 1.18
Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2. Am J Hum Genet (2009) 1.17
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation. Biochimie (2007) 1.17
Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism. Diabetes (2008) 1.17
Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats. Biol Psychiatry (2009) 1.17
Mutation in the gene encoding ubiquitin ligase LRSAM1 in patients with Charcot-Marie-Tooth disease. PLoS Genet (2010) 1.15
A pure population of ectodermal cells derived from human embryonic stem cells. Stem Cells (2007) 1.13
Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2. Cancer Res (2009) 1.12
Prospective comparison of 6 comorbidity indices as predictors of 1-year post-hospital discharge institutionalization, readmission, and mortality in elderly individuals. J Am Med Dir Assoc (2011) 1.11
Interleukin-8-induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts. J Biol Chem (2005) 1.09
Altered endoplasmic reticulum stress affects translation in inactive colon tissue from patients with ulcerative colitis. Gastroenterology (2011) 1.09
Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation. J Cell Sci (2006) 1.08
NOX5: from basic biology to signaling and disease. Free Radic Biol Med (2011) 1.08
CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network. J Biol Chem (2010) 1.07
Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma. PLoS One (2013) 1.06
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. ALTEX (2010) 1.06
New insights on NOX enzymes in the central nervous system. Antioxid Redox Signal (2014) 1.06
Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis. Biomaterials (2009) 1.06
Reactive oxygen species in myocardial reperfusion injury: from physiopathology to therapeutic approaches. Curr Pharm Biotechnol (2012) 1.05
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling. Arch Physiol Biochem (2006) 1.05
PTEN at the crossroad of metabolic diseases and cancer in the liver. Ann Hepatol (2008) 1.05
Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN. J Hepatol (2009) 1.04
Diesel exhaust particles induce matrix metalloprotease-1 in human lung epithelial cells via a NADP(H) oxidase/NOX4 redox-dependent mechanism. Am J Physiol Lung Cell Mol Physiol (2007) 1.03
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase. Oncogene (2005) 1.03
PPARs in Liver Diseases and Cancer: Epigenetic Regulation by MicroRNAs. PPAR Res (2012) 1.03
The HIV-1 Nef protein and phagocyte NADPH oxidase activation. J Biol Chem (2002) 1.02
Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease. Dis Model Mech (2013) 1.02
Haplotype-based banking of human pluripotent stem cells for transplantation: potential and limitations. Stem Cells Dev (2012) 1.02
A role for NOX NADPH oxidases in Alzheimer's disease and other types of dementia? IUBMB Life (2003) 1.02
Abnormal activation of autophagy-induced crinophagy in Paneth cells from patients with Crohn's disease. Gastroenterology (2012) 1.01
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons. Neurobiol Aging (2005) 1.01
Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms. Antivir Chem Chemother (2004) 1.01