Published in J Immunol on May 01, 2009
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Regulatory T cells require TCR signaling for their suppressive function. J Immunol (2015) 0.95
Influence of serum and soluble CD25 (sCD25) on regulatory and effector T-cell function in hepatocellular carcinoma. Scand J Immunol (2010) 0.93
The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells. J Immunol (2010) 0.92
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Injury induces early activation of T-cell receptor signaling pathways in CD4+ regulatory T cells. Shock (2011) 0.84
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SHARPIN controls the development of regulatory T cells. Immunology (2016) 0.81
The role of different subsets of regulatory T cells in immunopathogenesis of rheumatoid arthritis. Arthritis (2012) 0.81
Transplantation tolerance: Clinical potential of regulatory T cells. Self Nonself (2011) 0.79
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Local effects of regulatory T cells in MUC1 transgenic mice potentiate growth of MUC1 expressing tumor cells in vivo. PLoS One (2012) 0.76
Alginate Particles with Ovalbumin (OVA) Peptide Can Serve as a Carrier and Adjuvant for Immune Therapy in B16-OVA Cancer Model. Med Sci Monit Basic Res (2017) 0.75
CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells. Immunology (2015) 0.75
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature (2007) 7.82
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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol (2006) 6.16
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Role of LAG-3 in regulatory T cells. Immunity (2004) 4.36
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From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity (2006) 3.56
Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. J Immunol (2007) 3.47
Activated CD4+CD25+ T cells selectively kill B lymphocytes. Blood (2006) 2.42
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Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity. J Immunol (2005) 1.29
Control of organ-specific autoimmunity by immunoregulatory CD4(+)CD25(+) T cells. Microbes Infect (2001) 1.21
Distinct molecular program imposed on CD4+ T cell targets by CD4+CD25+ regulatory T cells. J Immunol (2006) 1.01
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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol (2004) 10.60
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol (2008) 10.26
The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature (2007) 7.82
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Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res (2011) 3.81
IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol (2010) 3.43
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Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex. Science (2008) 2.99
Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nat Methods (2006) 2.87
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol (2009) 2.52
Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). J Immunol (2005) 2.34
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nat Immunol (2008) 2.34
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity (2009) 2.34
Development of 2A peptide-based strategies in the design of multicistronic vectors. Expert Opin Biol Ther (2005) 2.31
The plasticity and stability of regulatory T cells. Nat Rev Immunol (2013) 2.15
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo. J Immunol (2004) 2.00
Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature (2013) 1.99
General nature of the STAT3-activated anti-inflammatory response. J Immunol (2006) 1.90
Regulatory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner. J Immunol (2009) 1.89
The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells. Eur J Immunol (2003) 1.80
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Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 1.74
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The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol (2012) 1.63
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Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity (2012) 1.61
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Retracted Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. J Immunol (2011) 1.56
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Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin. Proc Natl Acad Sci U S A (2008) 1.42
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol (2002) 1.41
LAG-3 regulates plasmacytoid dendritic cell homeostasis. J Immunol (2009) 1.33
Metalloproteases regulate T-cell proliferation and effector function via LAG-3. EMBO J (2007) 1.31
Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype. J Immunol (2002) 1.28
Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3. J Immunol (2011) 1.28
Once a Treg, always a Treg? Immunol Rev (2014) 1.27
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Organization of proximal signal initiation at the TCR:CD3 complex. Immunol Rev (2009) 1.25
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The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues. J Immunol (2002) 1.22
Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35. Diabetes (2012) 1.21
Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily. Immunol Res (2011) 1.19
The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function. J Immunol (2005) 1.13
Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer. J Immunol (2004) 1.13
Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development. EMBO J (2010) 1.11
Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4. Eur J Immunol (2010) 1.09
Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol (2012) 1.09
Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes (2012) 1.09
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells. J Immunol (2010) 1.07
The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling. J Immunol (2008) 1.05
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Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc Natl Acad Sci U S A (2011) 0.98
CD40-induced aggregation of MHC class II and CD80 on the cell surface leads to an early enhancement in antigen presentation. J Immunol (2003) 0.98
Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223). J Immunol (2004) 0.98
Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development. J Immunol (2007) 0.97
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Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family. Mol Immunol (2012) 0.94
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. Proc Natl Acad Sci U S A (2013) 0.94
Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways. J Immunol (2011) 0.93
Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells. J Immunol Methods (2002) 0.92
T cell-driven initiation and propagation of autoimmune diabetes. Curr Opin Immunol (2011) 0.92
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LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood (2011) 0.91
TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx. J Leukoc Biol (2005) 0.91
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Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection. J Immunol (2014) 0.89
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Interpreting mixed signals: the cell's cytokine conundrum. Curr Opin Immunol (2011) 0.88
The battle against immunopathology: infectious tolerance mediated by regulatory T cells. Cell Mol Life Sci (2011) 0.87
Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice. J Clin Invest (2011) 0.86
Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation. J Immunol (2004) 0.86
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A (2012) 0.85
Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. J Immunol Methods (2008) 0.85
Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo. J Immunol (2008) 0.84
Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind. Diabetes (2012) 0.83