PubRank

Toshio Suda

Author PubWeight™ 245.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004 12.67
2 Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 2006 7.62
3 Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004 7.21
4 Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 2007 5.94
5 Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell 2010 4.90
6 Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab 2006 4.33
7 Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell 2007 4.31
8 Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. J Exp Med 2009 4.03
9 DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med 2005 4.02
10 v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med 2006 3.78
11 A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med 2012 3.33
12 Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol 2002 3.08
13 Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell 2008 2.69
14 Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med 2009 2.66
15 Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem 2003 2.59
16 Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell 2013 2.58
17 p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 2011 2.58
18 Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 2010 2.47
19 Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. Cell 2012 2.36
20 M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 2009 2.29
21 Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol 2003 2.24
22 Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ Res 2007 2.22
23 The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev 2005 2.18
24 Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest. Cell Stem Cell 2008 2.14
25 Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. Dev Biol 2004 2.13
26 Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab 2009 2.13
27 Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev 2008 2.12
28 The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage. Development 2006 2.07
29 VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment. Arterioscler Thromb Vasc Biol 2008 1.90
30 Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. J Exp Med 2011 1.79
31 Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood 2010 1.78
32 Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4. Cancer Res 2003 1.78
33 Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci 2007 1.78
34 Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J 2005 1.77
35 Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Blood 2005 1.75
36 Angiopoietin-1 promotes lymphatic sprouting and hyperplasia. Blood 2005 1.71
37 Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction. Biochem Biophys Res Commun 2007 1.66
38 Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation. J Exp Med 2002 1.63
39 Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J Immunol 2007 1.62
40 Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med 2005 1.61
41 The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med 2010 1.59
42 Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche. Biochem Biophys Res Commun 2007 1.45
43 Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell 2007 1.44
44 Hematopoietic cells regulate the angiogenic switch during tumorigenesis. Blood 2004 1.44
45 Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo. Circ Res 2004 1.40
46 Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy. Trends Mol Med 2005 1.40
47 Cancer stem cells and their niche. Cancer Sci 2009 1.39
48 Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J Biol Chem 2009 1.39
49 Angiopoietin-related/angiopoietin-like proteins regulate angiogenesis. Int J Hematol 2004 1.37
50 CD24 is expressed specifically in the nucleus pulposus of intervertebral discs. Biochem Biophys Res Commun 2005 1.32
51 Regulation of reactive oxygen species in stem cells and cancer stem cells. J Cell Physiol 2012 1.30
52 Induction of DC-STAMP by alternative activation and downstream signaling mechanisms. J Bone Miner Res 2007 1.30
53 Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells. J Bone Miner Metab 2006 1.29
54 Pathological neoangiogenesis depends on oxidative stress regulation by ATM. Nat Med 2012 1.26
55 Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells. Blood 2010 1.25
56 Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development. Proc Natl Acad Sci U S A 2005 1.20
57 Differentiation and function of osteoclasts. Keio J Med 2003 1.20
58 Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice. J Clin Invest 2008 1.18
59 Suppression of ocular inflammation in endotoxin-induced uveitis by blocking the angiotensin II type 1 receptor. Invest Ophthalmol Vis Sci 2005 1.18
60 Angiopoietins and angiopoietin-like proteins in angiogenesis. Endothelium 2006 1.18
61 Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin. Proc Natl Acad Sci U S A 2009 1.17
62 Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification. J Exp Med 2007 1.16
63 Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. Proc Natl Acad Sci U S A 2003 1.15
64 Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow. Cell Stem Cell 2010 1.14
65 Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell 2013 1.14
66 Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol 2008 1.14
67 Derivation and morphological characterization of mouse spermatogonial stem cell lines. Arch Histol Cytol 2004 1.14
68 Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells. Blood 2002 1.12
69 Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization. Arterioscler Thromb Vasc Biol 2006 1.12
70 FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging. Blood 2008 1.12
71 A germ cell-specific gene, Prmt5, works in somatic cell reprogramming. J Biol Chem 2011 1.08
72 Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis. Biochem Biophys Res Commun 2008 1.07
73 Ephrin-B2 induces migration of endothelial cells through the phosphatidylinositol-3 kinase pathway and promotes angiogenesis in adult vasculature. Arterioscler Thromb Vasc Biol 2003 1.07
74 Bone marrow-derived cells serve as proangiogenic macrophages but not endothelial cells in wound healing. Blood 2011 1.06
75 Regulation of hematopoietic stem cells by the niche. Trends Cardiovasc Med 2005 1.06
76 Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration. Blood 2012 1.06
77 Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun 2009 1.05
78 Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver. Blood 2010 1.05
79 Cell fusion in osteoclasts plays a critical role in controlling bone mass and osteoblastic activity. Biochem Biophys Res Commun 2008 1.04
80 Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc. Biochem Biophys Res Commun 2008 1.04
81 Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression. Arterioscler Thromb Vasc Biol 2014 1.03
82 Spatial analysis of germ stem cell development in Oct-4/EGFP transgenic mice. Arch Histol Cytol 2004 1.03
83 Defective smooth muscle development in qkI-deficient mice. Dev Growth Differ 2004 1.03
84 A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis. Biochem Biophys Res Commun 2002 1.02
85 Niche regulation of hematopoietic stem cells in the endosteum. Ann N Y Acad Sci 2009 1.02
86 Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy. Sci Transl Med 2013 1.02
87 DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. Circ Res 2010 1.02
88 MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner. Biochem Biophys Res Commun 2009 1.01
89 Mechanism of hypercalcemia in adult T-cell leukemia: overexpression of receptor activator of nuclear factor kappaB ligand on adult T-cell leukemia cells. Blood 2002 1.01
90 Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells. Biochem Biophys Res Commun 2011 1.01
91 The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. Int Immunol 2008 1.00
92 Angiopoietin-related growth factor (AGF) promotes angiogenesis. Blood 2004 1.00
93 Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism. Blood 2011 1.00
94 Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity. Stem Cells 2008 0.99
95 von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development 2010 0.99
96 A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells. Biochem Biophys Res Commun 2005 0.98
97 Regulation of hematopoiesis and its interaction with stem cell niches. Int J Hematol 2005 0.97
98 TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool. Blood 2010 0.97
99 Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model. Arterioscler Thromb Vasc Biol 2008 0.96
100 Dimer formation of receptor activator of nuclear factor kappaB induces incomplete osteoclast formation. Biochem Biophys Res Commun 2004 0.96
101 The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells. Blood 2014 0.96
102 Neuropilin-1 on hematopoietic cells as a source of vascular development. Blood 2002 0.96
103 Comparative gene expression analysis of zebrafish and mammals identifies common regulators in hematopoietic stem cells. Blood 2009 0.95
104 Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells. Blood 2002 0.95
105 Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation. Blood 2011 0.94
106 The expression of platelet endothelial cell adhesion molecule-1 in mouse primordial germ cells during their migration and early gonadal formation. Histochem Cell Biol 2003 0.94
107 Functional differences between two Tie2 ligands, angiopoietin-1 and -2, in regulation of adult bone marrow hematopoietic stem cells. Exp Hematol 2009 0.93
108 Osteoblast-specific Angiopoietin 1 overexpression increases bone mass. Biochem Biophys Res Commun 2007 0.93
109 Dynamic regulation of Th17 differentiation by oxygen concentrations. Int Immunol 2011 0.93
110 Distinct roles of ephrin-B2 forward and EphB4 reverse signaling in endothelial cells. Arterioscler Thromb Vasc Biol 2003 0.93
111 Hematopoietic stem cell niche: an interplay among a repertoire of multiple functional niches. Biochim Biophys Acta 2012 0.92
112 Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene. Biochem Biophys Res Commun 2005 0.92
113 Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Invest Ophthalmol Vis Sci 2005 0.92
114 Isolation and expression patterns of genes for three angiopoietin-like proteins, Angptl1, 2 and 6 in zebrafish. Gene Expr Patterns 2005 0.92
115 Roles of the hypoxia response system in hematopoietic and leukemic stem cells. Int J Hematol 2012 0.91
116 Distribution of lymphatic vessels in mouse thymus: immunofluorescence analysis. Cell Tissue Res 2006 0.90
117 Effect of direct angiogenesis inhibition in rheumatoid arthritis using a soluble vascular endothelial growth factor receptor 1 chimeric protein. J Rheumatol 2002 0.90
118 The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner. Dev Biol 2011 0.90
119 Angiopoietins contribute to lung development by regulating pulmonary vascular network formation. Biochem Biophys Res Commun 2009 0.89
120 Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis. J Cell Sci 2009 0.89
121 Two anatomically distinct niches regulate stem cell activity. Blood 2012 0.89
122 Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression. Blood 2010 0.89
123 Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells. Blood 2013 0.88
124 Optimal ratio of transcription factors for somatic cell reprogramming. J Biol Chem 2012 0.88
125 Differentiation of arterial and venous endothelial cells and vascular morphogenesis. Endothelium 2006 0.88
126 Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells. Biochem Biophys Res Commun 2013 0.88
127 An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity. Development 2013 0.87
128 1-Alpha, 25-dihydroxy vitamin D3 inhibits osteoclastogenesis through IFN-beta-dependent NFATc1 suppression. J Bone Miner Metab 2009 0.87
129 Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J Cell Biol 2008 0.87
130 Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proc Natl Acad Sci U S A 2011 0.86
131 Feedback mechanism between blood vessels and astrocytes in retinal vascular development. Trends Cardiovasc Med 2009 0.86
132 Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice. Biochem Biophys Res Commun 2008 0.86
133 Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin. Biochem Biophys Res Commun 2014 0.86
134 Osteoclastic activity induces osteomodulin expression in osteoblasts. Biochem Biophys Res Commun 2007 0.86
135 Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche. Ann N Y Acad Sci 2012 0.85
136 Premeiotic germ cell defect in seminiferous tubules of Atm-null testis. Biochem Biophys Res Commun 2006 0.84
137 Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis. Biochem Biophys Res Commun 2006 0.84
138 Analysis of human TIE2 function on hematopoietic stem cells in umbilical cord blood. Biochem Biophys Res Commun 2002 0.83
139 Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med 2011 0.83
140 Regulation of cell cycle in hematopoietic stem cells by the niche. Cell Cycle 2004 0.83
141 Nucleostemin in injury-induced liver regeneration. Stem Cells Dev 2012 0.83
142 Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress. Blood 2013 0.82
143 Induction of pluripotent stem cells from primordial germ cells by single reprogramming factors. Stem Cells 2013 0.82
144 A CTX family cell adhesion molecule, JAM4, is expressed in stem cell and progenitor cell populations of both male germ cell and hematopoietic cell lineages. Mol Cell Biol 2006 0.81
145 N-cadherin+ HSCs in fetal liver exhibit higher long-term bone marrow reconstitution activity than N-cadherin- HSCs. Biochem Biophys Res Commun 2012 0.81
146 Aging of the hematopoietic stem cells niche. Int J Hematol 2014 0.81
147 Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice. Biochem Biophys Res Commun 2012 0.81
148 Neovascular niche for human myeloma cells in immunodeficient mouse bone. PLoS One 2012 0.81
149 Regulation of hematopoietic stem cells in the osteoblastic niche. Adv Exp Med Biol 2007 0.81
150 R-spondins/Lgrs expression in tooth development. Dev Dyn 2014 0.80
151 Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis. Arthritis Res Ther 2008 0.80
152 TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. PLoS One 2012 0.80
153 International workshop: radiation effects on mutation in somatic and germline stem cells. Int J Radiat Biol 2012 0.79
154 [Differentiation and function of monocyte/macrophage lineage cells and osteoblasts]. Nihon Rinsho 2005 0.79
155 Enhanced Angpt1/Tie2 signaling affects the differentiation and long-term repopulation ability of hematopoietic stem cells. Biochem Biophys Res Commun 2012 0.79
156 Administration of PDE4 inhibitors suppressed the pannus-like inflammation by inhibition of cytokine production by macrophages and synovial fibroblast proliferation. Mediators Inflamm 2007 0.79
157 OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets. PLoS One 2013 0.78
158 Identification of drug candidate against prostate cancer from the aspect of somatic cell reprogramming. Cancer Sci 2013 0.78
159 Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Stem Cells 2015 0.78
160 Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder. Blood 2013 0.78
161 Acquisition of G₀ state by CD34-positive cord blood cells after bone marrow transplantation. Exp Hematol 2010 0.78
162 Tracing the conversion process from primordial germ cells to pluripotent stem cells in mice. Biol Reprod 2012 0.78
163 Cell adhesion to ephrinb2 is induced by EphB4 independently of its kinase activity. Biochem Biophys Res Commun 2004 0.77
164 Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival. Blood 2005 0.77
165 [Cancer stem cell concepts--lesson from leukemia]. Nihon Rinsho 2009 0.76
166 Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes. Immunol Lett 2002 0.76
167 Conversion of primordial germ cells to pluripotent stem cells: methods for cell tracking and culture conditions. Methods Mol Biol 2013 0.76
168 Vascularity of nongynecological leiomyosarcoma depends on colony-stimulating factor 1 but not on vascular endothelial growth factor. Am J Pathol 2011 0.75
169 Opening the door for HIF1α tuning. Blood 2014 0.75
170 Passing a baton to the next generation. Int J Hematol 2012 0.75
171 New IJH guidelines highlight greater transparency. Int J Hematol 2011 0.75
172 Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. Elife 2017 0.75
173 Expression and function of NJ-1 surface antigen in megakaryopoiesis. Biochem Biophys Res Commun 2002 0.75
174 Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during medaka development, as revealed by the abnormal karyotype of erythrocytes in the medaka TFDP1 mutant. Dev Dyn 2015 0.75
175 Maintenance of hematopoietic stem cell integrity and regulation of leukemogenesis by p53 and its coactivator Aspp1. Rinsho Ketsueki 2015 0.75
176 For the further development of the International Journal of Hematology. Int J Hematol 2006 0.75
177 [Regulation of self-renewal of hematopoietic stem cells in the niche]. Tanpakushitsu Kakusan Koso 2005 0.75
178 [Hematopoietic stem cell niche in bone marrow]. Seikagaku 2006 0.75
179 [Regulation of hematopoietic stem cells in niche signaling]. Nihon Rinsho 2012 0.75
180 Correction: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. J Exp Med 2015 0.75