Published in PLoS One on May 29, 2009
Molecular basis of infrared detection by snakes. Nature (2010) 2.40
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli. Proc Natl Acad Sci U S A (2011) 1.56
Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Genetics (2011) 1.37
New research journals are needed and can compete with titans. Temperature (Austin) (2013) 1.05
Evolution of vertebrate transient receptor potential vanilloid 3 channels: opposite temperature sensitivity between mammals and western clawed frogs. PLoS Genet (2011) 0.97
Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates. J Biol Chem (2012) 0.95
Salinity tolerance in plants. Quantitative approach to ion transport starting from halophytes and stepping to genetic and protein engineering for manipulating ion fluxes. Front Plant Sci (2015) 0.90
Signaling by sensory receptors. Cold Spring Harb Perspect Biol (2012) 0.90
Phase maintenance in a rhythmic motor pattern during temperature changes in vivo. J Neurophysiol (2014) 0.90
New strategies to develop novel pain therapies: addressing thermoreceptors from different points of view. Pharmaceuticals (Basel) (2011) 0.87
Molecular mechanisms of temperature adaptation. J Physiol (2015) 0.80
TRP channels: a missing bond in the entrainment mechanism of peripheral clocks throughout evolution. Temperature (Austin) (2015) 0.79
Expression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolution. PeerJ (2015) 0.77
Evolution of Heat Sensors Drove Shifts in Thermosensation between Xenopus Species Adapted to Different Thermal Niches. J Biol Chem (2016) 0.76
Why individual thermo sensation and pain perception varies? Clue of disruptive mutations in TRPVs from 2504 human genome data. Channels (Austin) (2016) 0.75
Thermosensors or not, this is the question. Temperature (Austin) (2015) 0.75
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
TRP channels as cellular sensors. Nature (2003) 12.03
Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 8.94
A TRP channel that senses cold stimuli and menthol. Cell (2002) 8.66
TRP channels. Annu Rev Biochem (2007) 8.09
The menthol receptor TRPM8 is the principal detector of environmental cold. Nature (2007) 6.16
TRPM8 is required for cold sensation in mice. Neuron (2007) 5.25
Attenuated cold sensitivity in TRPM8 null mice. Neuron (2007) 4.73
Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell (2002) 4.57
Trp ion channels and temperature sensation. Annu Rev Neurosci (2006) 4.35
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. Nat Neurosci (2005) 4.00
Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4. J Neurosci (2005) 2.21
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron (2004) 2.19
The evolution and physiology of human color vision: insights from molecular genetic studies of visual pigments. Neuron (1999) 2.15
Evolutionary dynamics of olfactory and other chemosensory receptor genes in vertebrates. J Hum Genet (2006) 1.94
Xenopus, the next generation: X. tropicalis genetics and genomics. Dev Dyn (2002) 1.37
Evolution of thermoTRP ion channel homologs in vertebrates. Physiol Genomics (2006) 1.35
Coiled coils direct assembly of a cold-activated TRP channel. Neuron (2006) 1.33
From peppers to peppermints: natural products as probes of the pain pathway. Harvey Lect (2007) 0.99
Transient receptor potential ion channels control thermoregulatory behaviour in reptiles. PLoS One (2007) 0.93
Thermoregulation responses of broiler chickens to humidity at different ambient temperatures. I. One week of age. Poult Sci (2005) 0.84
Core temperature in the female rat: effect of ovariectomy and induction of pseudopregnancy. Am J Physiol (1976) 0.80
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell (2006) 11.01
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature (2004) 9.66
Cellular and molecular mechanisms of pain. Cell (2009) 9.36
Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 8.94
The menthol receptor TRPM8 is the principal detector of environmental cold. Nature (2007) 6.16
Structure of the TRPV1 ion channel determined by electron cryo-microscopy. Nature (2013) 5.75
TRP channel activation by reversible covalent modification. Proc Natl Acad Sci U S A (2006) 5.41
TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci U S A (2007) 5.27
The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci (2006) 4.93
Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell (2002) 4.57
Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci U S A (2005) 4.20
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2007) 4.10
TRPV1 structures in distinct conformations reveal activation mechanisms. Nature (2013) 3.62
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science (2003) 3.51
Lessons from peppers and peppermint: the molecular logic of thermosensation. Curr Opin Neurobiol (2003) 3.14
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci (2011) 2.90
Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature (2006) 2.47
Molecular basis of infrared detection by snakes. Nature (2010) 2.40
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron (2004) 2.19
International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. Pharmacol Rev (2005) 2.13
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature (2011) 1.84
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. J Neurosci (2005) 1.83
The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci (2002) 1.82
A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell (2010) 1.82
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating. Neuron (2008) 1.79
TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids. Neuron (2013) 1.73
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci (2008) 1.66
International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels. Pharmacol Rev (2003) 1.61
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli. Proc Natl Acad Sci U S A (2011) 1.56
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature (2011) 1.49
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. J Neurosci (2008) 1.48
Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci (2011) 1.40
Coiled coils direct assembly of a cold-activated TRP channel. Neuron (2006) 1.33
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proc Natl Acad Sci U S A (2008) 1.24
Changes in anxiety-related behaviors and hypothalamic-pituitary-adrenal activity in mice lacking the 5-HT-3A receptor. Physiol Behav (2004) 1.03
Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit. J Neurosci (2004) 0.97
Receptor-targeting mechanisms of pain-causing toxins: How ow? Toxicon (2012) 0.95
Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J Comp Neurol (2004) 0.92
Multiple unbiased prospective screens identify TRP channels and their conserved gating elements. J Gen Physiol (2008) 0.92
Fire in the hole: pore dilation of the capsaicin receptor TRPV1. Nat Neurosci (2008) 0.90
Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat. Eur J Neurosci (2004) 0.90
Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature (2015) 0.87
TRP channel structural biology: new roles for an old fold. Neuron (2007) 0.82
Toward better pain control. Sci Am (2006) 0.82
Neuroanatomical evidence for segregation of nerve fibers conveying light touch and pain sensation in Eimer's organ of the mole. Proc Natl Acad Sci U S A (2006) 0.81
Ion pair reinforced semi-interpenetrating polymer network for direct methanol fuel cell applications. J Phys Chem B (2012) 0.75