Published in Nature on December 05, 2013
TRPV1 structures in distinct conformations reveal activation mechanisms. Nature (2013) 3.62
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell (2014) 3.25
Three-dimensional structure of human γ-secretase. Nature (2014) 2.84
Beam-induced motion correction for sub-megadalton cryo-EM particles. Elife (2014) 2.66
Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature (2015) 2.47
Electron microscopy: Ultrastable gold substrates for electron cryomicroscopy. Science (2014) 1.95
Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6. Elife (2015) 1.91
Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions. Acta Crystallogr D Biol Crystallogr (2015) 1.89
The revolution will not be crystallized: a new method sweeps through structural biology. Nature (2015) 1.85
Structure of the mammalian ribosome-Sec61 complex to 3.4 Å resolution. Cell (2014) 1.80
Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy. Proc Natl Acad Sci U S A (2014) 1.76
Single-Particle Cryo-EM at Crystallographic Resolution. Cell (2015) 1.74
A molecular framework for temperature-dependent gating of ion channels. Cell (2014) 1.64
Structure of a mammalian ryanodine receptor. Nature (2014) 1.61
Architecture of mammalian respiratory complex I. Nature (2014) 1.60
Structural mechanism of glutamate receptor activation and desensitization. Nature (2014) 1.58
A primer to single-particle cryo-electron microscopy. Cell (2015) 1.56
2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy. Elife (2015) 1.52
Cryo-EM enters a new era. Elife (2014) 1.48
Intracellular long-chain acyl CoAs activate TRPV1 channels. PLoS One (2014) 1.41
Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Nat Struct Mol Biol (2017) 1.40
Architecture and conformational switch mechanism of the ryanodine receptor. Nature (2014) 1.39
Mechanistic insights into the recycling machine of the SNARE complex. Nature (2015) 1.38
Trajectories of the ribosome as a Brownian nanomachine. Proc Natl Acad Sci U S A (2014) 1.29
Structural DNA nanotechnology: state of the art and future perspective. J Am Chem Soc (2014) 1.25
Piezo1 ion channel pore properties are dictated by C-terminal region. Nat Commun (2015) 1.22
Feeling the hidden mechanical forces in lipid bilayer is an original sense. Proc Natl Acad Sci U S A (2014) 1.22
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature (2016) 1.19
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery. Cell (2016) 1.19
Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity. Mol Cell (2015) 1.17
Screening and large-scale expression of membrane proteins in mammalian cells for structural studies. Nat Protoc (2014) 1.16
Transient receptor potential channels in the vasculature. Physiol Rev (2015) 1.14
CryoEM at IUCrJ: a new era. IUCrJ (2016) 1.12
The development of cryo-EM into a mainstream structural biology technique. Nat Methods (2016) 1.12
Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel. Nat Chem Biol (2015) 1.11
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature (2014) 1.09
Near-atomic resolution for one state of F-actin. Structure (2014) 1.09
Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to Sub-tomogram Averaging. Structure (2015) 1.07
Mechanically Activated Ion Channels. Neuron (2015) 1.07
EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy. Nat Methods (2015) 1.07
De novo protein structure determination from near-atomic-resolution cryo-EM maps. Nat Methods (2015) 1.05
Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six. Neuron (2014) 1.05
Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K+ channel: the power of native nanodiscs. Proc Natl Acad Sci U S A (2014) 1.04
From foe to friend: using animal toxins to investigate ion channel function. J Mol Biol (2014) 1.04
Physical basis of apparent pore dilation of ATP-activated P2X receptor channels. Nat Neurosci (2015) 1.04
Direct evidence for functional TRPV1/TRPA1 heteromers. Pflugers Arch (2014) 1.03
Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage. J Struct Biol (2015) 1.02
Cryo-electron microscopy structure of the TRPV2 ion channel. Nat Struct Mol Biol (2016) 1.00
TRPA1 channels: molecular sentinels of cellular stress and tissue damage. J Physiol (2016) 0.98
Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels. Neuron (2014) 0.98
Seeing tobacco mosaic virus through direct electron detectors. J Struct Biol (2014) 0.97
Covariance Matrix Estimation for the Cryo-EM Heterogeneity Problem. SIAM J Imaging Sci (2015) 0.96
Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Res (2015) 0.95
2.9 Å Resolution Cryo-EM 3D Reconstruction of Close-Packed Virus Particles. Structure (2016) 0.95
Regulation of TRPV1 ion channel by phosphoinositide (4,5)-bisphosphate: the role of membrane asymmetry. J Biol Chem (2014) 0.94
The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA. Elife (2014) 0.94
Crystal structure of the epithelial calcium channel TRPV6. Nature (2016) 0.94
Volta phase plate cryo-EM of the small protein complex Prx3. Nat Commun (2016) 0.94
Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana. Nature (2016) 0.94
Regulation of the temperature-dependent activation of transient receptor potential vanilloid 1 (TRPV1) by phospholipids in planar lipid bilayers. J Biol Chem (2015) 0.93
Single particle electron cryo-microscopy of a mammalian ion channel. Curr Opin Struct Biol (2014) 0.93
Amphipols for each season. J Membr Biol (2014) 0.93
A structural view of ligand-dependent activation in thermoTRP channels. Front Physiol (2014) 0.92
Structural studies of the C-terminal tail of polycystin-2 (PC2) reveal insights into the mechanisms used for the functional regulation of PC2. J Physiol (2016) 0.92
Single-step antibody-based affinity cryo-electron microscopy for imaging and structural analysis of macromolecular assemblies. J Struct Biol (2014) 0.91
Structure and function of mitochondrial membrane protein complexes. BMC Biol (2015) 0.91
Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart. J Mol Biol (2014) 0.91
Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin. Elife (2016) 0.90
Resolution advances in cryo-EM enable application to drug discovery. Curr Opin Struct Biol (2016) 0.90
Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels. Front Physiol (2015) 0.90
3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography. Sci Rep (2015) 0.90
Vascular TRP channels: performing under pressure and going with the flow. Physiology (Bethesda) (2014) 0.89
Unravelling biological macromolecules with cryo-electron microscopy. Nature (2016) 0.89
A national facility for biological cryo-electron microscopy. Acta Crystallogr D Biol Crystallogr (2015) 0.89
Factors that Influence the Formation and Stability of Thin, Cryo-EM Specimens. Biophys J (2015) 0.89
The recombinant expression systems for structure determination of eukaryotic membrane proteins. Protein Cell (2014) 0.89
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin. Proc Natl Acad Sci U S A (2015) 0.89
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation. PLoS One (2015) 0.89
An algorithm for estimation and correction of anisotropic magnification distortion of cryo-EM images without need of pre-calibration. J Struct Biol (2016) 0.89
Architecture of the polyketide synthase module: surprises from electron cryo-microscopy. Curr Opin Struct Biol (2015) 0.88
Membrane Repair: Mechanisms and Pathophysiology. Physiol Rev (2015) 0.88
Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol (2015) 0.88
Transient receptor potential channels as targets for phytochemicals. ACS Chem Neurosci (2014) 0.88
Targeting TRP channels for novel migraine therapeutics. ACS Chem Neurosci (2014) 0.87
Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports. Sci Rep (2014) 0.87
Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation. J Gen Physiol (2014) 0.87
Cryo electron microscopy to determine the structure of macromolecular complexes. Methods (2015) 0.87
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating. Proc Natl Acad Sci U S A (2014) 0.87
Structural plasticity of helical nanotubes based on coiled-coil assemblies. Structure (2015) 0.87
Structural biology of TRP channels. Handb Exp Pharmacol (2014) 0.87
Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1. Cell Res (2016) 0.87
Navigating 3D electron microscopy maps with EM-SURFER. BMC Bioinformatics (2015) 0.86
Activity and Ca²⁺ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons. Elife (2015) 0.86
Optimized negative staining: a high-throughput protocol for examining small and asymmetric protein structure by electron microscopy. J Vis Exp (2014) 0.86
Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels. J Gen Physiol (2015) 0.86
Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations. J Biol Chem (2015) 0.86
ThermoTRPs and Pain. Neuroscientist (2015) 0.86
Unveiling TRPV1 spatio-temporal organization in live cell membranes. PLoS One (2015) 0.85
High temperature sensitivity is intrinsic to voltage-gated potassium channels. Elife (2014) 0.85
Proton block of proton-activated TRPV1 current. J Gen Physiol (2015) 0.85
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science (2005) 17.70
Accurate determination of local defocus and specimen tilt in electron microscopy. J Struct Biol (2003) 14.19
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature (2007) 12.35
RELION: implementation of a Bayesian approach to cryo-EM structure determination. J Struct Biol (2012) 10.13
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Nat Methods (2013) 8.12
TRP channels. Annu Rev Biochem (2007) 8.09
Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science (2005) 7.82
The crystal structure of a voltage-gated sodium channel. Nature (2011) 7.82
An introduction to TRP channels. Annu Rev Physiol (2006) 7.52
HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph (1996) 6.48
Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proc Natl Acad Sci U S A (2002) 5.91
FREALIGN: high-resolution refinement of single particle structures. J Struct Biol (2006) 5.85
Prevention of overfitting in cryo-EM structure determination. Nat Methods (2012) 5.65
Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles. Elife (2013) 4.42
TRPV1 structures in distinct conformations reveal activation mechanisms. Nature (2013) 3.62
3.88 A structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy. Nature (2008) 3.57
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron (2007) 3.48
3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry. Cell (2010) 3.40
Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution. Cell (2002) 3.26
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature (2007) 3.23
Ion channel voltage sensors: structure, function, and pathophysiology. Neuron (2010) 3.16
TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat Neurosci (2008) 3.08
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97
Permeation and selectivity of TRP channels. Annu Rev Physiol (2006) 2.96
TRP channels and pain. Annu Rev Cell Dev Biol (2013) 2.94
Sensing voltage across lipid membranes. Nature (2008) 2.66
Gating of TRP channels: a voltage connection? J Physiol (2005) 2.30
Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91
Targeting TRP channels for pain relief. Eur J Pharmacol (2013) 1.90
Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1. EMBO J (2011) 1.90
Outer pore architecture of a Ca2+-selective TRP channel. J Biol Chem (2004) 1.79
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating. Neuron (2008) 1.79
Structure of TRPV1 channel revealed by electron cryomicroscopy. Proc Natl Acad Sci U S A (2008) 1.77
Amphipols from A to Z. Annu Rev Biophys (2011) 1.75
TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids. Neuron (2013) 1.73
A primer on ankyrin repeat function in TRP channels and beyond. Mol Biosyst (2008) 1.70
Structure-functional intimacies of transient receptor potential channels. Q Rev Biophys (2009) 1.57
The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas. J Mol Biol (2006) 1.54
BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies. Protein Expr Purif (2008) 1.53
Kinetic and energetic analysis of thermally activated TRPV1 channels. Biophys J (2010) 1.51
Transient receptor potential channelopathies. Pflugers Arch (2010) 1.40
Structural determinants of gating in the TRPV1 channel. Nat Struct Mol Biol (2009) 1.33
Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1). J Neurosci (2007) 1.23
Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels. Channels (Austin) (2007) 1.20
A 3.5-nm structure of rat TRPV4 cation channel revealed by Zernike phase-contrast cryoelectron microscopy. J Biol Chem (2009) 1.20
Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutations. PLoS One (2011) 1.13
Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition. J Vis Exp (2011) 1.05
Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels. J Biol Chem (2010) 1.02
Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry (2012) 0.97
Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel. Biochim Biophys Acta (2012) 0.88
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell (2006) 11.01
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature (2004) 9.66
Cellular and molecular mechanisms of pain. Cell (2009) 9.36
Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 8.94
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Nat Methods (2013) 8.12
The menthol receptor TRPM8 is the principal detector of environmental cold. Nature (2007) 6.16
Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online (2004) 6.14
Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature (2005) 5.44
TRP channel activation by reversible covalent modification. Proc Natl Acad Sci U S A (2006) 5.41
TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci U S A (2007) 5.27
The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci (2006) 4.93
Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell (2002) 4.57
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry. Mol Cell (2007) 4.54
Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci U S A (2005) 4.20
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2007) 4.10
TRPV1 structures in distinct conformations reveal activation mechanisms. Nature (2013) 3.62
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science (2003) 3.51
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases. Mol Cell (2008) 3.49
Lessons from peppers and peppermint: the molecular logic of thermosensation. Curr Opin Neurobiol (2003) 3.14
Activation of leukocyte beta2 integrins by conversion from bent to extended conformations. Immunity (2006) 3.11
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Aquaporin-0 membrane junctions reveal the structure of a closed water pore. Nature (2004) 2.94
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies. Proc Natl Acad Sci U S A (2008) 2.93
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci (2011) 2.90
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell (2005) 2.82
In vitro self-assembly of tailorable nanotubes from a simple protein building block. Proc Natl Acad Sci U S A (2008) 2.71
HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Traffic (2010) 2.47
Spider toxins activate the capsaicin receptor to produce inflammatory pain. Nature (2006) 2.47
Molecular basis of infrared detection by snakes. Nature (2010) 2.40
Structure and different conformational states of native AMPA receptor complexes. Nature (2005) 2.22
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron (2004) 2.19
International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. Pharmacol Rev (2005) 2.13
The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell (2003) 1.99
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem (2011) 1.96
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature (2011) 1.84
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. J Neurosci (2005) 1.83
The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci (2002) 1.82
A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain. Cell (2010) 1.82
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature (2004) 1.81
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating. Neuron (2008) 1.79
TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids. Neuron (2013) 1.73
Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity (2004) 1.70
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci (2008) 1.66
The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes. Nature (2009) 1.64
Aquaporin-0 membrane junctions form upon proteolytic cleavage. J Mol Biol (2004) 1.63
International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels. Pharmacol Rev (2003) 1.61
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. EMBO J (2009) 1.60
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli. Proc Natl Acad Sci U S A (2011) 1.56
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc Natl Acad Sci U S A (2008) 1.55
Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Mol Cell (2007) 1.53
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature (2011) 1.49
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. J Neurosci (2008) 1.48
Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci (2011) 1.40
Influence of electron dose rate on electron counting images recorded with the K2 camera. J Struct Biol (2013) 1.35
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell (2013) 1.35
GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors. J Struct Biol (2010) 1.35
Coiled coils direct assembly of a cold-activated TRP channel. Neuron (2006) 1.33
Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008. Appl Environ Microbiol (2005) 1.31
Fabs enable single particle cryoEM studies of small proteins. Structure (2012) 1.25
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proc Natl Acad Sci U S A (2008) 1.24
Evolution of thermal response properties in a cold-activated TRP channel. PLoS One (2009) 1.22
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature (2013) 1.21
HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes. Proc Natl Acad Sci U S A (2010) 1.17
Structure of CD84 provides insight into SLAM family function. Proc Natl Acad Sci U S A (2007) 1.17
Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition. J Vis Exp (2011) 1.05
Changes in anxiety-related behaviors and hypothalamic-pituitary-adrenal activity in mice lacking the 5-HT-3A receptor. Physiol Behav (2004) 1.03
Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. J Struct Biol (2006) 1.01
Evaluation of imaging plates as recording medium for images of negatively stained single particles and electron diffraction patterns of two-dimensional crystals. J Electron Microsc (Tokyo) (2009) 0.99
A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis. Biochim Biophys Acta (2009) 0.99
Electron tomography of swollen rigor fibers of insect flight muscle reveals a short and variably angled S2 domain. J Mol Biol (2006) 0.98
Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit. J Neurosci (2004) 0.97
Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins. Biol Chem (2006) 0.97
A method for integrative structure determination of protein-protein complexes. Bioinformatics (2012) 0.97
Reconfiguration of the proteasome during chaperone-mediated assembly. Nature (2013) 0.96
Receptor-targeting mechanisms of pain-causing toxins: How ow? Toxicon (2012) 0.95
Structure characterization of the 26S proteasome. Biochim Biophys Acta (2010) 0.95
Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis. Proc Natl Acad Sci U S A (2014) 0.94
A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase. J Virol (2004) 0.93
Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J Comp Neurol (2004) 0.92
Multiple unbiased prospective screens identify TRP channels and their conserved gating elements. J Gen Physiol (2008) 0.92
Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm. Opt Express (2014) 0.92
Self-aligning amelogenin nanoribbons in oil-water system. J Struct Biol (2010) 0.91
Fire in the hole: pore dilation of the capsaicin receptor TRPV1. Nat Neurosci (2008) 0.90
Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat. Eur J Neurosci (2004) 0.90
Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev Cell (2013) 0.90
Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Biomacromolecules (2012) 0.88
Self-assembly of amelogenin proteins at the water-oil interface. Eur J Oral Sci (2011) 0.88
Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature (2015) 0.87
A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction. Ultramicroscopy (2011) 0.85
Collecting electron crystallographic data of two-dimensional protein crystals. Methods Enzymol (2010) 0.82
TRP channel structural biology: new roles for an old fold. Neuron (2007) 0.82
Toward better pain control. Sci Am (2006) 0.82
Estrogen, neuroprotection and neurogenesis after ischemic stroke. Curr Drug Targets (2012) 0.81
Neuroanatomical evidence for segregation of nerve fibers conveying light touch and pain sensation in Eimer's organ of the mole. Proc Natl Acad Sci U S A (2006) 0.81
Alumina surfaces with nanoscale topography reduce attachment and biofilm formation by Escherichia coli and Listeria spp. Biofouling (2014) 0.81
Polymorphic assemblies and crystalline arrays of lens tetraspanin MP20. J Mol Biol (2007) 0.79