Bridging IRES elements in mRNAs to the eukaryotic translation apparatus.

PubWeight™: 1.62‹?› | Rank: Top 4%

🔗 View Article (PMC 2783899)

Published in Biochim Biophys Acta on July 23, 2009

Authors

Kerry D Fitzgerald1, Bert L Semler

Author Affiliations

1: Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA 92697, USA.

Articles citing this

One core, two shells: bacterial and eukaryotic ribosomes. Nat Struct Mol Biol (2012) 1.77

Cell-free protein synthesis: applications come of age. Biotechnol Adv (2011) 1.72

Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138. J Virol (2010) 1.29

Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6. Cell (2013) 1.26

Enterovirus infections of the central nervous system. Virology (2011) 1.24

Host factors in enterovirus 71 replication. J Virol (2011) 1.19

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. PLoS Pathog (2011) 1.17

The emerging role of mTORC1 signaling in placental nutrient-sensing. Placenta (2012) 1.12

Structural features of the Seneca Valley virus internal ribosome entry site (IRES) element: a picornavirus with a pestivirus-like IRES. J Virol (2011) 1.05

Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus. PLoS Pathog (2011) 1.04

Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach. Mol Cell Proteomics (2011) 1.02

The genome-linked protein VPg of vertebrate viruses - a multifaceted protein. Curr Opin Virol (2011) 1.00

The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element. Nucleic Acids Res (2010) 1.00

Poliovirus unlinks TIA1 aggregation and mRNA stress granule formation. J Virol (2011) 0.99

Activity of the human immunodeficiency virus type 1 cell cycle-dependent internal ribosomal entry site is modulated by IRES trans-acting factors. Nucleic Acids Res (2011) 0.99

Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting. Mol Cell Biol (2012) 0.99

Picornavirus modification of a host mRNA decay protein. MBio (2012) 0.98

Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections. J Virol (2013) 0.96

Viral subversion of host functions for picornavirus translation and RNA replication. Future Virol (2012) 0.93

Two independent mechanisms promote expression of an N-terminal truncated USP18 isoform with higher DeISGylation activity in the nucleus. J Biol Chem (2011) 0.92

S6K2: The Neglected S6 Kinase Family Member. Front Oncol (2013) 0.92

The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation. PLoS One (2012) 0.91

IRES-mediated translation of membrane proteins and glycoproteins in eukaryotic cell-free systems. PLoS One (2013) 0.90

The genetic code as expressed through relationships between mRNA structure and protein function. FEBS Lett (2013) 0.89

Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation. Nucleic Acids Res (2013) 0.87

High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71. RNA Biol (2013) 0.86

Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation. Nucleic Acids Res (2014) 0.86

Poly(A)-binding protein facilitates translation of an uncapped/nonpolyadenylated viral RNA by binding to the 3' untranslated region. J Virol (2012) 0.86

Gemin5 proteolysis reveals a novel motif to identify L protease targets. Nucleic Acids Res (2012) 0.85

A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1. Open Biol (2014) 0.84

The 5' UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed -1 ribosomal frameshift that generates HIV-1 enzymes. RNA (2012) 0.84

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling. Nucleic Acids Res (2014) 0.84

Basic anatomy and tumor biology of the RPS6KA6 gene that encodes the p90 ribosomal S6 kinase-4. Oncogene (2012) 0.84

Differential role for host translation factors in host and viral protein synthesis during human cytomegalovirus infection. J Virol (2013) 0.84

Functional and structural analysis of the internal ribosome entry site present in the mRNA of natural variants of the HIV-1. PLoS One (2012) 0.84

DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. Nucleic Acids Res (2015) 0.83

Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication. J Virol (2013) 0.82

Cell-Free Protein Synthesis: Pros and Cons of Prokaryotic and Eukaryotic Systems. Chembiochem (2015) 0.81

Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway. J Biol Chem (2010) 0.81

Localized IRES-dependent translation of ER chaperone protein mRNA in sensory axons. PLoS One (2012) 0.81

DSPP contains an IRES element responsible for the translation of dentin phosphophoryn. J Dent Res (2013) 0.80

A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells. Nucleic Acids Res (2014) 0.80

Differential restriction patterns of mRNA decay factor AUF1 during picornavirus infections. J Gen Virol (2014) 0.79

Differential cleavage of IRES trans-acting factors (ITAFs) in cells infected by human rhinovirus. Virology (2013) 0.79

Kinetics of initiating polypeptide elongation in an IRES-dependent system. Elife (2016) 0.79

To be or not to be: the regulation of mRNA fate as a survival strategy during mammalian hibernation. Cell Stress Chaperones (2014) 0.78

SMAD4-dependent polysome RNA recruitment in human pancreatic cancer cells. Mol Carcinog (2011) 0.78

Differential regulation of polysome mRNA levels in mouse Hepa-1C1C7 cells exposed to dioxin. Toxicol In Vitro (2011) 0.78

Analysis of cellulose synthase genes from domesticated apple identifies collinear genes WDR53 and CesA8A: partial co-expression, bicistronic mRNA, and alternative splicing of CESA8A. J Exp Bot (2012) 0.78

Death of a dogma: eukaryotic mRNAs can code for more than one protein. Nucleic Acids Res (2015) 0.77

A comprehensive analysis of the importance of translation initiation factors for Haloferax volcanii applying deletion and conditional depletion mutants. PLoS One (2013) 0.77

The 5' untranslated region of the human T-cell lymphotropic virus type 1 mRNA enables cap-independent translation initiation. J Virol (2014) 0.77

Molecular Analysis of RNA-RNA Interactions between 5' and 3' Untranslated Regions during the Initiation of Translation of a Cardiovirulent and a Live-Attenuated Coxsackievirus B3 Strains. Int J Mol Sci (2013) 0.76

Translation initiation of the HIV-1 mRNA. Translation (Austin) (2014) 0.76

Potential natural products for Alzheimer's disease: targeted search using the internal ribosome entry site of tau and amyloid-β precursor protein. Int J Mol Sci (2015) 0.76

Human Cytomegalovirus Strategies to Maintain and Promote mRNA Translation. Viruses (2016) 0.76

PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1. Nucleic Acids Res (2017) 0.75

Impaired binding of standard initiation factors eIF3b, eIF4G and eIF4B to domain V of the live-attenuated coxsackievirus B3 Sabin3-like IRES--alternatives for 5'UTR-related cardiovirulence mechanisms. Diagn Pathol (2013) 0.75

Additive Promotion of Viral Internal Ribosome Entry Site-Mediated Translation by Far Upstream Element-Binding Protein 1 and an Enterovirus 71-Induced Cleavage Product. PLoS Pathog (2016) 0.75

Using temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo. Methods Enzymol (2011) 0.75

Tailoring the switch from IRES-dependent to 5'-end-dependent translation with the RNase P ribozyme. RNA (2010) 0.75

Stress Granules and Virus Replication. Future Virol (2015) 0.75

Oncolytic Seneca Valley Virus: past perspectives and future directions. Oncolytic Virother (2016) 0.75

Ribosomal Initiation Complex Assembly within the Wild-Strain of Coxsackievirus B3 and Live-Attenuated Sabin3-like IRESes during the Initiation of Translation. Int J Mol Sci (2013) 0.75

Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation. FEBS J (2016) 0.75

Mammalian Polycistronic mRNAs and Disease. Trends Genet (2016) 0.75

IRES-Mediated Protein Translation Overcomes Suppression by the p14ARF Tumor Suppressor Protein. J Cancer (2017) 0.75

Articles cited by this

(truncated to the top 100)

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res (1984) 39.52

The scanning model for translation: an update. J Cell Biol (1989) 31.23

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature (1988) 19.07

Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell (2009) 14.51

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol (1988) 13.93

Messenger-RNA-binding proteins and the messages they carry. Nat Rev Mol Cell Biol (2002) 8.81

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex. J Biol Chem (1982) 7.82

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. Genes Dev (1998) 7.72

Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev (2001) 7.60

c-MYC: more than just a matter of life and death. Nat Rev Cancer (2002) 6.73

Short RNAs repress translation after initiation in mammalian cells. Mol Cell (2006) 6.70

Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry. Mol Cell Biol (1996) 6.35

La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J Virol (1993) 5.89

Internal initiation of translation mediated by the 5' leader of a cellular mRNA. Nature (1991) 5.88

Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat Genet (2001) 5.09

Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region. Mol Cell Biol (1988) 4.97

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc Natl Acad Sci U S A (1993) 4.71

Initiation of protein synthesis from the A site of the ribosome. Cell (2000) 4.56

In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysate. J Virol (1984) 4.54

Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J Virol (1987) 4.52

Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes. Mol Cell Biol (1996) 4.42

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science (2007) 4.33

An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell (2007) 4.03

An RNA sequence of hundreds of nucleotides at the 5' end of poliovirus RNA is involved in allowing viral protein synthesis. J Virol (1988) 3.93

Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A. Nat Chem Biol (2006) 3.89

Conservation of the secondary structure elements of the 5'-untranslated region of cardio- and aphthovirus RNAs. Nucleic Acids Res (1989) 3.81

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure. RNA (2001) 3.65

Translation of poliovirus RNA in vitro: changes in cleavage pattern and initiation sites by ribosomal salt wash. Virology (1979) 3.61

Mechanism of ribosome recruitment by hepatitis C IRES RNA. RNA (2001) 3.55

Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. J Virol (1997) 3.40

RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol Rev (1996) 3.36

Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs. J Virol (1998) 3.33

Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA. RNA (1995) 3.28

Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex. J Virol (1988) 3.28

Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase. Cell Host Microbe (2007) 3.21

A phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation. J Virol (1999) 3.13

Identification and characterization of a novel cell cycle-regulated internal ribosome entry site. Mol Cell (2000) 2.98

A cell cycle-dependent internal ribosome entry site. Mol Cell (2000) 2.91

Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus. J Mol Biol (2002) 2.90

Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA. Genes Dev (2003) 2.89

A second protease of foot-and-mouth disease virus. J Virol (1986) 2.87

A cell cycle-dependent protein serves as a template-specific translation initiation factor. Genes Dev (2000) 2.84

Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor. Cell (2004) 2.84

Cellular internal ribosome entry segments: structures, trans-acting factors and regulation of gene expression. Oncogene (2004) 2.78

Searching for IRES. RNA (2006) 2.78

Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro. J Virol (1999) 2.70

Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol Cell Biol (1998) 2.59

unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev (1999) 2.59

Internal ribosome entry sites in cellular mRNAs: mystery of their existence. J Biol Chem (2005) 2.57

The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. J Gen Virol (1993) 2.51

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proc Natl Acad Sci U S A (1996) 2.47

The La antigen binds 5' noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc Natl Acad Sci U S A (1997) 2.43

Selective translation initiation by ribosome jumping in adenovirus-infected and heat-shocked cells. Genes Dev (1996) 2.42

Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nat Struct Mol Biol (2006) 2.32

Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro. J Virol (1994) 2.30

The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. Mol Cell (2003) 2.28

Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment. Nucleic Acids Res (2000) 2.22

An enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virus. J Virol (2000) 2.21

Structural analysis of the interaction of the pyrimidine tract-binding protein with the internal ribosomal entry site of encephalomyocarditis virus and foot-and-mouth disease virus RNAs. RNA (1996) 2.19

Alternative mechanisms of initiating translation of mammalian mRNAs. Biochem Soc Trans (2005) 2.17

Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J Biol Chem (1997) 2.17

New ways of initiating translation in eukaryotes? Mol Cell Biol (2001) 2.11

A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs. Nucleic Acids Res (1997) 2.05

Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements. RNA (1999) 2.00

Low efficiency of the 5' nontranslated region of hepatitis A virus RNA in directing cap-independent translation in permissive monkey kidney cells. J Virol (1994) 2.00

Polypyrimidine-tract binding protein (PTB) is necessary, but not sufficient, for efficient internal initiation of translation of human rhinovirus-2 RNA. RNA (1999) 1.98

Cleavage of Poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff? J Virol (1999) 1.98

Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus. J Virol (1991) 1.97

Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures. RNA (2004) 1.96

A second look at cellular mRNA sequences said to function as internal ribosome entry sites. Nucleic Acids Res (2005) 1.93

Identification and characterization of a cis-acting replication element (cre) adjacent to the internal ribosome entry site of foot-and-mouth disease virus. J Virol (2002) 1.88

Structural and mechanistic insights into hepatitis C viral translation initiation. Nat Rev Microbiol (2006) 1.87

La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro. Mol Cell Biol (2004) 1.87

Internal initiation in Saccharomyces cerevisiae mediated by an initiator tRNA/eIF2-independent internal ribosome entry site element. Proc Natl Acad Sci U S A (2001) 1.87

Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo. Oncogene (2003) 1.83

Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis. Proc Natl Acad Sci U S A (2003) 1.83

The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. Mol Cell Biol (2003) 1.74

Functional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3. Nucleic Acids Res (1998) 1.72

Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication. J Virol (2002) 1.71

A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. EMBO J (2006) 1.71

Differentiation-induced internal translation of c-sis mRNA: analysis of the cis elements and their differentiation-linked binding to the hnRNP C protein. Mol Cell Biol (1999) 1.70

More precise location of the polycytidylic acid tract in foot and mouth disease virus RNA. J Virol (1978) 1.69

A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons. J Biol Chem (2003) 1.67

Translation initiation by factor-independent binding of eukaryotic ribosomes to internal ribosomal entry sites. C R Biol (2005) 1.65

Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway. Oncogene (1998) 1.62

Dual initiation sites of protein synthesis on foot-and-mouth disease virus RNA are selected following internal entry and scanning of ribosomes in vivo. EMBO J (1992) 1.60

Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease. J Virol (2002) 1.59

Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA. J Biol Chem (2004) 1.58

Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites. Proc Natl Acad Sci U S A (2009) 1.54

Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly. EMBO Rep (2004) 1.53

Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. Genes Dev (2005) 1.53

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo. RNA (2000) 1.51

Activity of the hepatitis A virus IRES requires association between the cap-binding translation initiation factor (eIF4E) and eIF4G. J Virol (2001) 1.50

Intact eukaryotic initiation factor 4G is required for hepatitis A virus internal initiation of translation. Virology (1997) 1.46

Assessing IRES activity in the HIF-1alpha and other cellular 5' UTRs. RNA (2006) 1.45

Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs. Mol Cell Biol (2007) 1.44

Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol Biol Cell (2007) 1.42

Restriction of translation of capped mRNA in vitro as a model for poliovirus-induced inhibition of host cell protein synthesis: relationship to p220 cleavage. J Virol (1987) 1.41

Structural insights into the transcriptional and translational roles of Ebp1. EMBO J (2007) 1.37

Functional interactions in internal translation initiation directed by viral and cellular IRES elements. J Gen Virol (2001) 1.37

Articles by these authors

Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication. J Virol (2002) 1.71

A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. EMBO J (2006) 1.71

Regulation of picornavirus gene expression. Microbes Infect (2004) 1.66

Cellular protein modification by poliovirus: the two faces of poly(rC)-binding protein. J Virol (2007) 1.51

Functional interaction of heterogeneous nuclear ribonucleoprotein C with poliovirus RNA synthesis initiation complexes. J Virol (2005) 1.48

Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138. J Virol (2010) 1.29

MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells. Cell Rep (2012) 1.22

Atomic force microscopy analysis of icosahedral virus RNA. J Mol Biol (2005) 1.21

Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES. RNA (2004) 1.21

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. PLoS Pathog (2011) 1.17

Allosteric effects of ligands and mutations on poliovirus RNA-dependent RNA polymerase. J Virol (2005) 1.11

An RNA virus hijacks an incognito function of a DNA repair enzyme. Proc Natl Acad Sci U S A (2012) 1.08

Cell-dependent role for the poliovirus 3' noncoding region in positive-strand RNA synthesis. J Virol (2004) 1.07

An internal ribosome entry site mediates translation of lymphoid enhancer factor-1. RNA (2005) 1.07

Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus. PLoS Pathog (2011) 1.04

Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity. Virology (2009) 1.01

The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation. Virology (2008) 1.01

An authentic 3' noncoding region is necessary for efficient poliovirus replication. J Virol (2005) 0.99

Picornavirus modification of a host mRNA decay protein. MBio (2012) 0.98

Subdomain specific functions of the RNA polymerase region of poliovirus 3CD polypeptide. Virology (2002) 0.98

Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections. J Virol (2013) 0.96

Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA. J Biol Chem (2004) 0.95

Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins. Virology (2010) 0.94

Viral subversion of host functions for picornavirus translation and RNA replication. Future Virol (2012) 0.93

Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate. J Virol (2010) 0.92

Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates. J Virol (2010) 0.91

Viral proteinase requirements for the nucleocytoplasmic relocalization of cellular splicing factor SRp20 during picornavirus infections. J Virol (2012) 0.87

Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity. PLoS One (2011) 0.87

Mechanistic intersections between picornavirus translation and RNA replication. Adv Virus Res (2011) 0.85

Strand-specific RNA synthesis determinants in the RNA-dependent RNA polymerase of poliovirus. J Virol (2004) 0.84

Functional conservation of the hydrophobic domain of polypeptide 3AB between human rhinovirus and poliovirus. Virology (2003) 0.84

Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication. J Virol (2013) 0.82

Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Nucleic Acids Res (2013) 0.82

Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein. Virus Res (2013) 0.82

Differential rescue of poliovirus RNA replication functions by genetically modified RNA polymerase precursors. J Virol (2004) 0.82

Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression. Gene (2007) 0.76

Resistance is futile. Nat Genet (2005) 0.75

In memoriam John J. Holland (1929-2013): a pioneer in molecular virology. J Virol (2014) 0.75

Methods to study RNA virus molecular biology. Methods (2013) 0.75