Published in J Biol Chem on October 09, 2009
Calcium-dependent phospholipid scrambling by TMEM16F. Nature (2010) 3.63
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
Function of alternative splicing. Gene (2012) 2.00
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel. Nat Commun (2013) 1.80
Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci U S A (2011) 1.79
TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol (2010) 1.74
Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem (2013) 1.74
Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology. Circ Res (2012) 1.69
International Union of Basic and Clinical Pharmacology. LXXXV: calcium-activated chloride channels. Pharmacol Rev (2011) 1.67
Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels? Acta Pharmacol Sin (2011) 1.64
Dynamic modulation of ANO1/TMEM16A HCO3(-) permeability by Ca2+/calmodulin. Proc Natl Acad Sci U S A (2012) 1.63
Expression profile and protein translation of TMEM16A in murine smooth muscle. Am J Physiol Cell Physiol (2010) 1.44
ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins. Am J Physiol Cell Physiol (2011) 1.43
TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels. Mol Cell Proteomics (2010) 1.43
Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels. Proc Natl Acad Sci U S A (2013) 1.41
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines. Br J Cancer (2010) 1.38
Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels. J Gen Physiol (2013) 1.30
Anoctamins. Pflugers Arch (2011) 1.29
Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin. J Gen Physiol (2014) 1.24
Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem (2011) 1.19
Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium. J Biol Chem (2010) 1.19
Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh) -A01. Br J Pharmacol (2013) 1.18
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension. Am J Physiol Cell Physiol (2012) 1.15
Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes. J Physiol (2013) 1.09
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia. J Physiol (2012) 1.09
A minimal isoform of the TMEM16A protein associated with chloride channel activity. Biochim Biophys Acta (2011) 1.08
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell (2012) 1.07
Pharmacological characterization of TMEM16A currents. Channels (Austin) (2014) 1.03
Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase? Pflugers Arch (2013) 1.02
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms. J Physiol (2015) 1.02
The significance of interstitial cells in neurogastroenterology. J Neurogastroenterol Motil (2014) 1.01
The secret life of CFTR as a calcium-activated chloride channel. J Physiol (2013) 1.01
Ca2+-activated Cl- channels at a glance. J Cell Sci (2012) 1.01
Activation and inhibition of TMEM16A calcium-activated chloride channels. PLoS One (2014) 0.97
Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A. J Gen Physiol (2016) 0.95
Activity of Ca -activated Cl channels contributes to regulating receptor- and store-operated Ca entry in human pulmonary artery smooth muscle cells. Pulm Circ (2011) 0.94
Independent activation of distinct pores in dimeric TMEM16A channels. J Gen Physiol (2016) 0.94
A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid. Pflugers Arch (2016) 0.92
Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A (2015) 0.92
The voltage dependence of the TMEM16B/anoctamin2 calcium-activated chloride channel is modified by mutations in the first putative intracellular loop. J Gen Physiol (2012) 0.92
Comprehensive exon array data processing method for quantitative analysis of alternative spliced variants. Nucleic Acids Res (2011) 0.92
Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing. BMC Mol Biol (2011) 0.92
Targeting ion channels for the treatment of gastrointestinal motility disorders. Therap Adv Gastroenterol (2012) 0.92
Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels. Pflugers Arch (2014) 0.92
Channel properties of the splicing isoforms of the olfactory calcium-activated chloride channel Anoctamin 2. J Gen Physiol (2013) 0.91
Non-canonical translation start sites in the TMEM16A chloride channel. Biochim Biophys Acta (2013) 0.90
Interactions between permeation and gating in the TMEM16B/anoctamin2 calcium-activated chloride channel. J Gen Physiol (2014) 0.89
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree. Eur J Hum Genet (2012) 0.89
TMEM16A knockdown abrogates two different Ca(2+)-activated Cl (-) currents and contractility of smooth muscle in rat mesenteric small arteries. Pflugers Arch (2013) 0.86
Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis. Pflugers Arch (2013) 0.86
Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons. J Gen Physiol (2015) 0.85
TMEM16A alternative splicing coordination in breast cancer. Mol Cancer (2013) 0.85
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6). FASEB J (2014) 0.85
9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels. Br J Pharmacol (2015) 0.84
Acidic amino acids in the first intracellular loop contribute to voltage- and calcium- dependent gating of anoctamin1/TMEM16A. PLoS One (2014) 0.83
Activation of the basolateral membrane Cl- conductance essential for electrogenic K+ secretion suppresses electrogenic Cl- secretion. Exp Physiol (2010) 0.83
Do we understand any more about bladder interstitial cells?-ICI-RS 2013. Neurourol Urodyn (2014) 0.82
Functional swapping between transmembrane proteins TMEM16A and TMEM16F. J Biol Chem (2014) 0.81
Inhibitory role of phosphatidylinositol 4,5-bisphosphate on TMEM16A-encoded calcium-activated chloride channels in rat pulmonary artery. Br J Pharmacol (2014) 0.81
Tailoring of membrane proteins by alternative splicing of pre-mRNA. Biochemistry (2012) 0.80
Influence of intracellular Ca2+ and alternative splicing on the pharmacological profile of ANO1 channels. Am J Physiol Cell Physiol (2016) 0.80
Gating modes of calcium-activated chloride channels TMEM16A and TMEM16B. J Physiol (2015) 0.80
Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function. PLoS Genet (2016) 0.79
Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice. Br J Pharmacol (2014) 0.78
Neuronal ClC-3 Splice Variants Differ in Subcellular Localizations, but Mediate Identical Transport Functions. J Biol Chem (2015) 0.78
Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels. Proc Natl Acad Sci U S A (2014) 0.78
Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance. Channels (Austin) (2015) 0.78
Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. J Clin Invest (2016) 0.77
CFTR induces extracellular acid sensing in Xenopus oocytes which activates endogenous Ca²⁺-activated Cl⁻ conductance. Pflugers Arch (2011) 0.77
A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2. Am J Physiol Gastrointest Liver Physiol (2015) 0.76
Assessment of the olfactory function in Italian patients with type 3 von Willebrand disease caused by a homozygous 253 Kb deletion involving VWF and TMEM16B/ANO2. PLoS One (2015) 0.76
Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle. Pulm Circ (2015) 0.76
Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. PLoS One (2015) 0.76
Epithelial Anion Transport as Modulator of Chemokine Signaling. Mediators Inflamm (2016) 0.75
Multiple transcripts of anoctamin genes expressed in the mouse submandibular salivary gland. J Periodontal Implant Sci (2015) 0.75
Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity. Sci Rep (2016) 0.75
Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels. Channels (Austin) (2015) 0.75
TMEM16 chloride channels are two-faced. J Gen Physiol (2016) 0.75
Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells. Sci Rep (2016) 0.75
EAVK "segment c" sequence confers Ca(2+)-dependent changes to the kinetics of full length human Ano1. Am J Physiol Gastrointest Liver Physiol (2017) 0.75
Molecular simulation assisted identification of Ca(2+) binding residues in TMEM16A. J Comput Aided Mol Des (2015) 0.75
Substituted 2-acylamino-cycloalkylthiophene-3-carboxylic acid arylamides as inhibitors of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A). J Med Chem (2017) 0.75
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science (2008) 8.74
TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature (2008) 8.40
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79
An RNA map predicting Nova-dependent splicing regulation. Nature (2006) 7.63
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell (1998) 6.72
Calcium-activated chloride channels. Annu Rev Physiol (2005) 4.67
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron (2000) 4.24
Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. Mol Cell Biol (2000) 4.12
The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol Cell Biol (2001) 3.68
A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG. EMBO J (2003) 3.44
Calcium-dependent chloride currents in isolated cells from rat lacrimal glands. J Physiol (1986) 2.85
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
Calcium-activated chloride conductance in frog olfactory cilia. J Neurosci (1991) 2.41
TMEM16B induces chloride currents activated by calcium in mammalian cells. Pflugers Arch (2009) 2.20
TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. J Neurosci (2009) 2.19
Neuronal Ca2+ -activated Cl- channels--homing in on an elusive channel species. Prog Neurobiol (2000) 2.11
Bimodal control of a Ca(2+)-activated Cl(-) channel by different Ca(2+) signals. J Gen Physiol (2000) 2.11
Calcium-activated chloride channels: (un)known, (un)loved? Proc Am Thorac Soc (2004) 1.82
Activation of calcium-dependent chloride channels in rat parotid acinar cells. J Gen Physiol (1996) 1.82
Differential regulation of Ca(2+)-activated Cl(-) currents in rabbit arterial and portal vein smooth muscle cells by Ca(2+)-calmodulin-dependent kinase. J Physiol (2001) 1.59
Calcium-activated chloride channels in bovine pulmonary artery endothelial cells. J Physiol (1997) 1.55
Intracellular Ca2+ and Cl- channel activation in secretory cells. Annu Rev Physiol (2000) 1.55
Inactivation of calcium-activated chloride channels in smooth muscle by calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A (1997) 1.44
Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances. J Gen Physiol (2002) 1.41
Mechanism of the inhibition of Ca2+-activated Cl- currents by phosphorylation in pulmonary arterial smooth muscle cells. J Gen Physiol (2006) 1.41
Inositol 3,4,5,6-tetrakisphosphate inhibits the calmodulin-dependent protein kinase II-activated chloride conductance in T84 colonic epithelial cells. J Biol Chem (1996) 1.38
A polar mechanism coordinates different regions of alternative splicing within a single gene. Mol Cell (2005) 1.26
Calcium dependence and distribution of calcium-activated chloride channels in Xenopus oocytes. J Physiol (1997) 1.23
Aspects of calcium-activated chloride currents: a neuronal perspective. Pharmacol Ther (1995) 1.18
Regulation of a human chloride channel. a paradigm for integrating input from calcium, type ii calmodulin-dependent protein kinase, and inositol 3,4,5,6-tetrakisphosphate. J Biol Chem (2001) 1.14
Characterization of calcium-activated chloride channels in patches excised from the dendritic knob of mammalian olfactory receptor neurons. J Membr Biol (1998) 1.11
Characterization of Ca2+-activated Cl- currents in mouse kidney inner medullary collecting duct cells. Am J Physiol Renal Physiol (2003) 1.06
Small-conductance chloride channels activated by calcium on cultured endocrine cells from mammalian pars intermedia. Pflugers Arch (1988) 1.03
Calmodulin contributes to gating control in olfactory calcium-activated chloride channels. J Gen Physiol (2006) 1.03
Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells. Am J Physiol Renal Physiol (2003) 0.97
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science (2008) 8.74
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest (2002) 4.97
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. J Clin Invest (2005) 4.19
Chloride channels as drug targets. Nat Rev Drug Discov (2008) 3.22
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol (2004) 3.10
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
HIV-1 Tat affects the programming and functionality of human CD8⁺ T cells by modulating the expression of T-box transcription factors. AIDS (2014) 2.54
Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance. Am J Hum Genet (2004) 2.35
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. J Biol Chem (2003) 2.25
MYH9-related disease: May-Hegglin anomaly, Sebastian syndrome, Fechtner syndrome, and Epstein syndrome are not distinct entities but represent a variable expression of a single illness. Medicine (Baltimore) (2003) 2.05
Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing. Hepatology (2009) 1.90
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem (2002) 1.89
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.87
Poland syndrome with bilateral features: case description with review of the literature. Am J Med Genet A (2009) 1.82
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol (2005) 1.80
A KCNH2 branch point mutation causing aberrant splicing contributes to an explanation of genotype-negative long QT syndrome. Heart Rhythm (2008) 1.59
Structure and function of TMEM16 proteins (anoctamins). Physiol Rev (2014) 1.56
Polymorphisms in the osteopontin promoter affect its transcriptional activity. Physiol Genomics (2004) 1.54
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus. Nature (2007) 1.46
TMEM16A protein: a new identity for Ca(2+)-dependent Cl⁻ channels. Physiology (Bethesda) (2010) 1.45
Gelsolin secretion in interleukin-4-treated bronchial epithelia and in asthmatic airways. Am J Respir Crit Care Med (2005) 1.45
TDP43 depletion rescues aberrant CFTR exon 9 skipping. FEBS Lett (2006) 1.45
Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis. Biochem J (2008) 1.44
Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera. Gastroenterology (2007) 1.42
Genetics, clinical and pathological features of glomerulonephritis associated with mutations of nonmuscle myosin IIA (Fechtner syndrome). Am J Kidney Dis (2003) 1.36
Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels. J Immunol (2007) 1.35
Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker. FEBS Lett (2004) 1.35
Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant. Mol Cell Biol (2008) 1.35
Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: confirmations and advancements. Eur J Hum Genet (2008) 1.34
An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing. J Biol Chem (2004) 1.31
CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis. Curr Pharm Des (2006) 1.30
Influence of cell background on pharmacological rescue of mutant CFTR. Am J Physiol Cell Physiol (2010) 1.28
Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease. Int J Mol Med (2006) 1.26
The presence of anti-Tat antibodies is predictive of long-term nonprogression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconverters. J Infect Dis (2005) 1.23
TCIRG1-dependent recessive osteopetrosis: mutation analysis, functional identification of the splicing defects, and in vitro rescue by U1 snRNA. Hum Mutat (2004) 1.21
Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem (2011) 1.19
Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS). Ann Rheum Dis (2012) 1.19
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro. J Immunol (2002) 1.18
Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2. Oncogene (2004) 1.16
Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models. J Biol Chem (2004) 1.16
Betaine, dimethyl sulfoxide, and 7-deaza-dGTP, a powerful mixture for amplification of GC-rich DNA sequences. J Mol Diagn (2006) 1.15
Epstein syndrome: another renal disorder with mutations in the nonmuscle myosin heavy chain 9 gene. Hum Genet (2001) 1.15
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation. Hum Mutat (2007) 1.14
A rare SMN2 variant in a previously unrecognized composite splicing regulatory element induces exon 7 inclusion and reduces the clinical severity of spinal muscular atrophy. Hum Mutat (2010) 1.14
Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications. Arthritis Rheum (2006) 1.13
HIV-1 tat protein modulates the generation of cytotoxic T cell epitopes by modifying proteasome composition and enzymatic activity. J Immunol (2004) 1.13
Candidate HIV-1 Tat vaccine development: from basic science to clinical trials. AIDS (2006) 1.12
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects. Hum Mol Genet (2012) 1.11
The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels. Exp Physiol (2011) 1.11
Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides. Chem Biol (2008) 1.09
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia. J Physiol (2012) 1.09
Influence of Friedreich ataxia GAA noncoding repeat expansions on pre-mRNA processing. Am J Hum Genet (2008) 1.09
A minimal isoform of the TMEM16A protein associated with chloride channel activity. Biochim Biophys Acta (2011) 1.08
A high proportion of DNA variants of BRCA1 and BRCA2 is associated with aberrant splicing in breast/ovarian cancer patients. Clin Cancer Res (2010) 1.08
Familial vesicoureteral reflux: testing replication of linkage in seven new multigenerational kindreds. J Am Soc Nephrol (2005) 1.08
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell (2012) 1.07
Molecular characterization of a t(2;6) balanced translocation that is associated with a complex phenotype and leads to truncation of the TCBA1 gene. Hum Mutat (2005) 1.06
Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07. Br J Pharmacol (2002) 1.05
A recessive gene for primary vesicoureteral reflux maps to chromosome 12p11-q13. J Am Soc Nephrol (2009) 1.04
Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse. Mol Ther (2009) 1.04
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. Am J Physiol Lung Cell Mol Physiol (2003) 1.03
The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: implications for the design of new vaccination strategies against AIDS. Vaccine (2007) 1.02
Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys. Vaccine (2004) 1.01
Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines. Am J Physiol Lung Cell Mol Physiol (2007) 1.00
HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection. J Immunol (2009) 1.00
A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia. Cancer Genet Cytogenet (2008) 0.99
A common haplotype at the 5' end of the RET proto-oncogene, overrepresented in Hirschsprung patients, is associated with reduced gene expression. Hum Mutat (2005) 0.98
Problems and emerging approaches in HIV/AIDS vaccine development. Expert Opin Emerg Drugs (2007) 0.98
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling. Am J Physiol Cell Physiol (2011) 0.98
Previously undescribed nonsense mutation in SHH caused autosomal dominant holoprosencephaly with wide intrafamilial variability. Am J Med Genet A (2003) 0.97
Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations. J Biol Chem (2011) 0.97
Functional studies on the ATM intronic splicing processing element. Nucleic Acids Res (2005) 0.97
A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein. FEBS Lett (2005) 0.97