Published in Mol Cell on November 25, 2009
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Close encounters for the first time: Helicase interactions with DNA damage. DNA Repair (Amst) (2015) 0.80
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ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle. PLoS One (2016) 0.77
The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients. J Gynecol Oncol (2015) 0.77
The nucleotide excision repair lesion-recognition protein Rad4 captures a pre-flipped partner base in a benzo[a]pyrene-derived DNA lesion: how structure impacts the binding pathway. Chem Res Toxicol (2017) 0.75
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Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1. Worm (2013) 0.75
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Dissociation Dynamics of XPC-RAD23B from Damaged DNA Is a Determining Factor of NER Efficiency. PLoS One (2016) 0.75
XPC: Going where no DNA damage sensor has gone before. DNA Repair (Amst) (2015) 0.75
Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos. PLoS One (2015) 0.75
The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition. Genetics (2016) 0.75
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UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell (2005) 3.85
Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition. Mol Cell (2003) 3.66
The comings and goings of nucleotide excision repair factors on damaged DNA. EMBO J (2003) 2.89
Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis. Mol Cell (2005) 2.88
Structure and mechanism of human DNA polymerase eta. Nature (2010) 2.69
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell (2008) 2.47
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Nature (2004) 2.40
Conformational change in the catalytic site of the ribonuclease YoeB toxin by YefM antitoxin. Mol Cell (2005) 2.32
Azathioprine and UVA light generate mutagenic oxidative DNA damage. Science (2005) 2.31
129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. J Exp Med (2003) 2.26
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. DNA Repair (Amst) (2007) 2.26
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Cell (2011) 2.16
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair. Mol Cell (2006) 2.13
Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature (2005) 2.11
High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J (2004) 2.07
Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst) (2008) 2.01
Interaction of hREV1 with three human Y-family DNA polymerases. Genes Cells (2004) 2.00
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity. Mol Cell Biol (2004) 1.85
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. J Exp Med (2005) 1.80
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Biochemistry (2002) 1.71
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Proc Natl Acad Sci U S A (2005) 1.67
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Proc Natl Acad Sci U S A (2002) 1.63
Rad54 dissociates homologous recombination intermediates by branch migration. Nat Struct Mol Biol (2007) 1.61
Crystal structure of the DNA repair enzyme ultraviolet damage endonuclease. Structure (2007) 1.59
Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein. Mol Cell Biol (2005) 1.58
Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions. J Biol Chem (2004) 1.53
A molecular mechanism for DNA damage recognition by the xeroderma pigmentosum group C protein complex. DNA Repair (Amst) (2002) 1.53
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J Biol Chem (2006) 1.49
Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro. Genes Cells (2003) 1.48
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. Proc Natl Acad Sci U S A (2002) 1.46
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A (2012) 1.44
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. J Biol Chem (2007) 1.44
Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. J Biol Chem (2002) 1.43
Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B. J Biol Chem (2003) 1.40
DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA. J Biol Chem (2005) 1.38
Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes. Proc Natl Acad Sci U S A (2009) 1.36
A novel role of DNA polymerase eta in modulating cellular sensitivity to chemotherapeutic agents. Mol Cancer Res (2006) 1.36
Identification of cryptochrome DASH from vertebrates. Genes Cells (2004) 1.36
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Nat Biotechnol (2004) 1.34
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol Cell Biol (2006) 1.34
Structure of the human GINS complex and its assembly and functional interface in replication initiation. Nat Struct Mol Biol (2007) 1.33
An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. J Biol Chem (2003) 1.30
Cyclin A-Cdk1 regulates the origin firing program in mammalian cells. Proc Natl Acad Sci U S A (2009) 1.29
The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assay. Biochemistry (2002) 1.26
Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates. EMBO J (2003) 1.25
Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation. Cancer Res (2005) 1.24
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C. J Biol Chem (2004) 1.23
DNA bending by the human damage recognition complex XPC-HR23B. DNA Repair (Amst) (2003) 1.20
Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex. J Biol Chem (2002) 1.20
Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B. Mol Cell Biol (2002) 1.20
The carboxy-terminal domain of the XPC protein plays a crucial role in nucleotide excision repair through interactions with transcription factor IIH. DNA Repair (Amst) (2002) 1.18
Cell cycle-dependent phosphorylation, nuclear localization, and activation of human condensin. J Biol Chem (2003) 1.18
REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Nucleic Acids Res (2008) 1.15
Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Genes Cells (2003) 1.15
Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Res (2003) 1.14
Analysis of the role of Aurora B on the chromosomal targeting of condensin I. Nucleic Acids Res (2007) 1.14
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A. Nat Struct Mol Biol (2009) 1.12
Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. Genes Cells (2008) 1.11
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. J Biol Chem (2002) 1.09
Crystal structure of SUMO-3-modified thymine-DNA glycosylase. J Mol Biol (2006) 1.09
A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest. Genes Cells (2006) 1.08
Localization of human Mcm10 is spatially and temporally regulated during the S phase. J Biol Chem (2004) 1.07
Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases. EMBO Rep (2003) 1.06
In vivo destabilization and functional defects of the xeroderma pigmentosum C protein caused by a pathogenic missense mutation. Mol Cell Biol (2007) 1.06
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions. PLoS Genet (2010) 1.06
Xeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylase. EMBO J (2003) 1.05
UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells. DNA Repair (Amst) (2009) 1.05
A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation. Genes Cells (2007) 1.05
A role for DNA polymerase beta in mutagenic UV lesion bypass. J Biol Chem (2002) 1.04
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. DNA Repair (Amst) (2006) 1.03
Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. DNA Repair (Amst) (2003) 1.03
Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo. Mutat Res (2005) 1.03
Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex. DNA Repair (Amst) (2004) 1.02
A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1. J Biol Chem (2001) 1.02
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. DNA Repair (Amst) (2009) 1.01
Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates. J Biol Chem (2004) 1.01
Efficiency of extension of mismatched primer termini across from cisplatin and oxaliplatin adducts by human DNA polymerases beta and eta in vitro. Biochemistry (2003) 1.01
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Mol Cell (2010) 1.01
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η. Proc Natl Acad Sci U S A (2013) 1.00
Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases. J Mol Biol (2008) 1.00
Dicer-related drh-3 gene functions in germ-line development by maintenance of chromosomal integrity in Caenorhabditis elegans. Genes Cells (2007) 0.99
DNA binding properties of human DNA polymerase eta: implications for fidelity and polymerase switching of translesion synthesis. Genes Cells (2004) 0.99