Published in Nucleic Acids Res on December 22, 2009
A draft sequence of the Neandertal genome. Science (2010) 19.55
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The complete genome sequence of a Neanderthal from the Altai Mountains. Nature (2013) 6.10
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The complete mitochondrial DNA genome of an unknown hominin from southern Siberia. Nature (2010) 3.90
Ancient human genomes suggest three ancestral populations for present-day Europeans. Nature (2014) 3.80
Massive migration from the steppe was a source for Indo-European languages in Europe. Nature (2015) 3.50
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Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse. Curr Biol (2015) 1.14
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Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Res (2013) 1.12
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Genomic insights into the origin of farming in the ancient Near East. Nature (2016) 1.07
Reconstructing ancient genomes and epigenomes. Nat Rev Genet (2015) 1.06
Epigenetic estimation of age in humpback whales. Mol Ecol Resour (2014) 1.06
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Ancient gene flow from early modern humans into Eastern Neanderthals. Nature (2016) 1.00
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The use of museum specimens with high-throughput DNA sequencers. J Hum Evol (2014) 0.99
Road blocks on paleogenomes--polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA. Nucleic Acids Res (2010) 0.98
High-resolution analysis of cytosine methylation in ancient DNA. PLoS One (2012) 0.96
Improving the performance of true single molecule sequencing for ancient DNA. BMC Genomics (2012) 0.92
A complete ancient RNA genome: identification, reconstruction and evolutionary history of archaeological Barley Stripe Mosaic Virus. Sci Rep (2014) 0.89
Genomic methylation patterns in archaeological barley show de-methylation as a time-dependent diagenetic process. Sci Rep (2014) 0.88
Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus. Elife (2016) 0.88
Analysis of human accelerated DNA regions using archaic hominin genomes. PLoS One (2012) 0.87
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. PLoS One (2011) 0.84
Optimization of DNA recovery and amplification from non-carbonized archaeobotanical remains. PLoS One (2014) 0.82
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Polymorphic NumtS trace human population relationships. Hum Genet (2011) 0.81
Hybridization Capture Using RAD Probes (hyRAD), a New Tool for Performing Genomic Analyses on Collection Specimens. PLoS One (2016) 0.80
Toward high-resolution population genomics using archaeological samples. DNA Res (2016) 0.79
Temporal patterns of damage and decay kinetics of DNA retrieved from plant herbarium specimens. R Soc Open Sci (2016) 0.79
Detection of Cytosine methylation in ancient DNA from five native american populations using bisulfite sequencing. PLoS One (2015) 0.79
Human evolution: a tale from ancient genomes. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Combined hybridization capture and shotgun sequencing for ancient DNA analysis of extinct wild and domestic dromedary camel. Mol Ecol Resour (2016) 0.77
Homo sapiens, Homo neanderthalensis and the Denisova specimen: New insights on their evolutionary histories using whole-genome comparisons. Genet Mol Biol (2012) 0.77
The major histocompatibility complex in Old World camelids and low polymorphism of its class II genes. BMC Genomics (2016) 0.76
Genomic analysis of 6,000-year-old cultivated grain illuminates the domestication history of barley. Nat Genet (2016) 0.76
Improving ancient DNA genome assembly. PeerJ (2017) 0.75
Systematic relationships of five newly sequenced cervid species. PeerJ (2016) 0.75
Fast, Accurate and Automatic Ancient Nucleosome and Methylation Maps with epiPALEOMIX. Mol Biol Evol (2016) 0.75
A High-Coverage Yersinia pestis Genome from a Sixth-Century Justinianic Plague Victim. Mol Biol Evol (2016) 0.75
Randomly broken fragment PCR with 5' end-directed adaptor for genome walking. Sci Rep (2013) 0.75
Artifactual mutations resulting from DNA lesions limit detection levels in ultrasensitive sequencing applications. DNA Res (2016) 0.75
Comparing Ancient DNA Preservation in Petrous Bone and Tooth Cementum. PLoS One (2017) 0.75
Detection of DNA sequences refractory to PCR amplification using a biophysical SERRS assay (Surface Enhanced Resonant Raman Spectroscopy). PLoS One (2014) 0.75
Computational analyses of ancient pathogen DNA from herbarium samples: challenges and prospects. Front Plant Sci (2015) 0.75
Epigenetics of Ancient DNA. Acta Naturae (2016) 0.75
Comparative performance of the BGISEQ-500 vs Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing. Gigascience (2017) 0.75
AntCaller: an accurate variant caller incorporating ancient DNA damage. Mol Genet Genomics (2017) 0.75
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
CpG islands in vertebrate genomes. J Mol Biol (1987) 23.16
DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet (2006) 18.08
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Metagenomics to paleogenomics: large-scale sequencing of mammoth DNA. Science (2005) 8.14
Continuous base identification for single-molecule nanopore DNA sequencing. Nat Nanotechnol (2009) 8.09
Sequencing and analysis of Neanderthal genomic DNA. Science (2006) 8.06
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli. J Biol Chem (1977) 7.24
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell (2008) 6.98
Analysis of one million base pairs of Neanderthal DNA. Nature (2006) 6.17
Patterns of damage in genomic DNA sequences from a Neandertal. Proc Natl Acad Sci U S A (2007) 6.12
Genetic analyses from ancient DNA. Annu Rev Genet (2004) 6.09
DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA. Nucleic Acids Res (2001) 6.06
Targeted retrieval and analysis of five Neandertal mtDNA genomes. Science (2009) 5.79
Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry (1974) 5.70
Improved base calling for the Illumina Genome Analyzer using machine learning strategies. Genome Biol (2009) 5.64
Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification. Proc Natl Acad Sci U S A (1989) 5.50
Recharacterization of ancient DNA miscoding lesions: insights in the era of sequencing-by-synthesis. Nucleic Acids Res (2006) 4.70
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing. Nucleic Acids Res (2007) 4.26
Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae. Nature (2005) 3.74
DNA damage and DNA sequence retrieval from ancient tissues. Nucleic Acids Res (1996) 3.56
Ancient DNA extraction from bones and teeth. Nat Protoc (2007) 3.42
Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions. Nucleic Acids Res (2007) 3.41
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA. Proc Natl Acad Sci U S A (2006) 3.40
Single nucleotide polymorphisms and recombination rate in humans. Trends Genet (2001) 2.91
Whole-genome shotgun sequencing of mitochondria from ancient hair shafts. Science (2007) 2.85
Characterization of genetic miscoding lesions caused by postmortem damage. Am J Hum Genet (2002) 2.61
The Neandertal genome and ancient DNA authenticity. EMBO J (2009) 2.46
The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res (1994) 2.37
Proboscidean mitogenomics: chronology and mode of elephant evolution using mastodon as outgroup. PLoS Biol (2007) 2.34
Revisiting Neandertal diversity with a 100,000 year old mtDNA sequence. Curr Biol (2006) 2.04
Characterization of Escherichia coli endonuclease VIII. J Biol Chem (1997) 1.80
Nuclear gene indicates coat-color polymorphism in mammoths. Science (2006) 1.77
Optimization of 454 sequencing library preparation from small amounts of DNA permits sequence determination of both DNA strands. Biotechniques (2009) 1.67
Inconsistencies in Neanderthal genomic DNA sequences. PLoS Genet (2007) 1.59
Methods for generating shotgun and mixed shotgun/paired-end libraries for the 454 DNA sequencer. Curr Protoc Hum Genet (2009) 1.24
Minimizing DNA contamination by using UNG-coupled quantitative real-time PCR on degraded DNA samples: application to ancient DNA studies. Biotechniques (2005) 1.15
Primer extension capture: targeted sequence retrieval from heavily degraded DNA sources. J Vis Exp (2009) 1.14
Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs. Nucleic Acids Res (2006) 0.95
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet (2007) 20.22
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
Sequencing and analysis of Neanderthal genomic DNA. Science (2006) 8.06
Intra- and interspecific variation in primate gene expression patterns. Science (2002) 7.92
A high-coverage genome sequence from an archaic Denisovan individual. Science (2012) 7.89
The evolution of gene expression levels in mammalian organs. Nature (2011) 7.16
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell (2008) 6.98
Illumina sequencing library preparation for highly multiplexed target capture and sequencing. Cold Spring Harb Protoc (2010) 6.39
Analysis of one million base pairs of Neanderthal DNA. Nature (2006) 6.17
Patterns of damage in genomic DNA sequences from a Neandertal. Proc Natl Acad Sci U S A (2007) 6.12
Genetic analyses from ancient DNA. Annu Rev Genet (2004) 6.09
Molecular evolution of FOXP2, a gene involved in speech and language. Nature (2002) 5.89
Genomewide comparison of DNA sequences between humans and chimpanzees. Am J Hum Genet (2002) 5.80
Targeted retrieval and analysis of five Neandertal mtDNA genomes. Science (2009) 5.79
Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science (2005) 5.68
Improved base calling for the Illumina Genome Analyzer using machine learning strategies. Genome Biol (2009) 5.64
A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature (2005) 5.51
Deep proteome and transcriptome mapping of a human cancer cell line. Mol Syst Biol (2011) 5.48
Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet (2005) 5.00
Evidence for gradients of human genetic diversity within and among continents. Genome Res (2004) 4.70
Early allelic selection in maize as revealed by ancient DNA. Science (2003) 4.38
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform. Nucleic Acids Res (2011) 4.33
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing. Nucleic Acids Res (2007) 4.26
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia. Nature (2010) 3.90
Accelerated evolution of conserved noncoding sequences in humans. Science (2006) 3.87
Regional patterns of gene expression in human and chimpanzee brains. Genome Res (2004) 3.84
No evidence of Neandertal mtDNA contribution to early modern humans. PLoS Biol (2004) 3.81
Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae. Nature (2005) 3.74
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell (2009) 3.63
A neutral explanation for the correlation of diversity with recombination rates in humans. Am J Hum Genet (2003) 3.57
Targeted high-throughput sequencing of tagged nucleic acid samples. Nucleic Acids Res (2007) 3.56
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
Parallel tagged sequencing on the 454 platform. Nat Protoc (2008) 3.49
A neutral model of transcriptome evolution. PLoS Biol (2004) 3.44
Genomic sequencing of Pleistocene cave bears. Science (2005) 3.40
The derived FOXP2 variant of modern humans was shared with Neandertals. Curr Biol (2007) 3.39
Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS One (2010) 3.35
Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary. BMC Evol Biol (2008) 3.21
A draft genome of Yersinia pestis from victims of the Black Death. Nature (2011) 3.18
Somatic mutations in cerebral cortical malformations. N Engl J Med (2014) 3.13
A complete mtDNA genome of an early modern human from Kostenki, Russia. Curr Biol (2009) 3.09
Evolution of primate gene expression. Nat Rev Genet (2006) 3.04
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells. Proc Natl Acad Sci U S A (2006) 3.03
PatMaN: rapid alignment of short sequences to large databases. Bioinformatics (2008) 2.77
Neanderthals in central Asia and Siberia. Nature (2007) 2.64
Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA. PLoS One (2012) 2.60
Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biol (2004) 2.56
Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution. Proc Natl Acad Sci U S A (2012) 2.54
The bonobo genome compared with the chimpanzee and human genomes. Nature (2012) 2.49
Targeted investigation of the Neandertal genome by array-based sequence capture. Science (2010) 2.49
The Neandertal genome and ancient DNA authenticity. EMBO J (2009) 2.46
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. Proc Natl Acad Sci U S A (2013) 2.45
Natural selection on the olfactory receptor gene family in humans and chimpanzees. Am J Hum Genet (2003) 2.44
The date of interbreeding between Neandertals and modern humans. PLoS Genet (2012) 2.35
Why do human diversity levels vary at a megabase scale? Genome Res (2005) 2.33
FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics (2007) 2.32
DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci U S A (2013) 2.31
Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Curr Biol (2008) 2.27
Human specific loss of olfactory receptor genes. Proc Natl Acad Sci U S A (2003) 2.23
Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol (2004) 2.22
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death. Proc Natl Acad Sci U S A (2011) 2.15
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The Neandertal type site revisited: interdisciplinary investigations of skeletal remains from the Neander Valley, Germany. Proc Natl Acad Sci U S A (2002) 1.98
The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine. Elife (2013) 1.84
Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol (2005) 1.82
Genome-wide comparison of medieval and modern Mycobacterium leprae. Science (2013) 1.81
Single-stranded DNA library preparation for the sequencing of ancient or damaged DNA. Nat Protoc (2013) 1.80
Transcriptional neoteny in the human brain. Proc Natl Acad Sci U S A (2009) 1.78
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A (2010) 1.76
Aging and gene expression in the primate brain. PLoS Biol (2005) 1.76