Published in Proc Natl Acad Sci U S A on January 22, 2013
The complete genome sequence of a Neanderthal from the Altai Mountains. Nature (2013) 6.10
Ancient human genomes suggest three ancestral populations for present-day Europeans. Nature (2014) 3.80
Massive migration from the steppe was a source for Indo-European languages in Europe. Nature (2015) 3.50
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature (2013) 2.75
Population genomics of Bronze Age Eurasia. Nature (2015) 2.58
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. Proc Natl Acad Sci U S A (2013) 2.45
A revised timescale for human evolution based on ancient mitochondrial genomes. Curr Biol (2013) 2.43
Genome-wide patterns of selection in 230 ancient Eurasians. Nature (2015) 2.09
Higher levels of neanderthal ancestry in East Asians than in Europeans. Genetics (2013) 2.06
Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries. Am J Hum Genet (2013) 1.92
A mitochondrial genome sequence of a hominin from Sima de los Huesos. Nature (2013) 1.85
Selective enrichment of damaged DNA molecules for ancient genome sequencing. Genome Res (2014) 1.62
An early modern human from Romania with a recent Neanderthal ancestor. Nature (2015) 1.51
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal. Proc Natl Acad Sci U S A (2014) 1.47
Chimpanzee genomic diversity reveals ancient admixture with bonobos. Science (2016) 1.41
Genomic insights into the peopling of the Southwest Pacific. Nature (2016) 1.32
Patterns of coding variation in the complete exomes of three Neandertals. Proc Natl Acad Sci U S A (2014) 1.29
Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins. Nature (2016) 1.27
Early Austronesians: into and out of Taiwan. Am J Hum Genet (2014) 1.18
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX. Nat Protoc (2014) 1.17
Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques. Proc Natl Acad Sci U S A (2015) 1.13
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Res (2013) 1.12
Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe. PLoS Genet (2014) 1.12
Partial uracil-DNA-glycosylase treatment for screening of ancient DNA. Philos Trans R Soc Lond B Biol Sci (2015) 1.11
Ancient mitochondrial DNA provides high-resolution time scale of the peopling of the Americas. Sci Adv (2016) 1.07
Genomic insights into the origin of farming in the ancient Near East. Nature (2016) 1.07
Toward a new history and geography of human genes informed by ancient DNA. Trends Genet (2014) 1.07
Ancient gene flow from early modern humans into Eastern Neanderthals. Nature (2016) 1.00
Ancient genomics. Philos Trans R Soc Lond B Biol Sci (2015) 0.99
Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649). Oncotarget (2014) 0.92
Improved calibration of the human mitochondrial clock using ancient genomes. Mol Biol Evol (2014) 0.91
Resolving the ancestry of Austronesian-speaking populations. Hum Genet (2016) 0.88
The Evolutionary Origin and Genetic Makeup of Domestic Horses. Genetics (2016) 0.87
The Demographic Development of the First Farmers in Anatolia. Curr Biol (2016) 0.86
Ancient DNA and human history. Proc Natl Acad Sci U S A (2016) 0.86
Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing. BMC Genomics (2014) 0.83
Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity. J Clin Endocrinol Metab (2016) 0.81
Identification of a new hominin bone from Denisova Cave, Siberia using collagen fingerprinting and mitochondrial DNA analysis. Sci Rep (2016) 0.81
Pros and cons of methylation-based enrichment methods for ancient DNA. Sci Rep (2015) 0.80
Ancient DNA reveals that the genetic structure of the northern han chinese was shaped prior to 3,000 years ago. PLoS One (2015) 0.80
Computer simulation of human leukocyte antigen genes supports two main routes of colonization by human populations in East Asia. BMC Evol Biol (2015) 0.80
Direct radiocarbon dating and genetic analyses on the purported Neanderthal mandible from the Monti Lessini (Italy). Sci Rep (2016) 0.79
Human evolution: a tale from ancient genomes. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
The study of human Y chromosome variation through ancient DNA. Hum Genet (2017) 0.78
Ancient population genomics and the study of evolution. Philos Trans R Soc Lond B Biol Sci (2015) 0.78
Inferences from tip-calibrated phylogenies: a review and a practical guide. Mol Ecol (2016) 0.78
The shaping of human diversity: filters, boundaries and transitions. Philos Trans R Soc Lond B Biol Sci (2016) 0.78
Re-inventing ancient human DNA. Investig Genet (2015) 0.78
Direct dating of Neanderthal remains from the site of Vindija Cave and implications for the Middle to Upper Paleolithic transition. Proc Natl Acad Sci U S A (2017) 0.78
Combined hybridization capture and shotgun sequencing for ancient DNA analysis of extinct wild and domestic dromedary camel. Mol Ecol Resour (2016) 0.77
Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route. PLoS One (2015) 0.77
A partial nuclear genome of the Jomons who lived 3000 years ago in Fukushima, Japan. J Hum Genet (2016) 0.77
Carriers of human mitochondrial DNA macrohaplogroup M colonized India from southeastern Asia. BMC Evol Biol (2016) 0.76
A Robust Framework for Microbial Archaeology. Annu Rev Genomics Hum Genet (2017) 0.75
Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA. Oncotarget (2016) 0.75
Discovery of the Fuyan teeth: challenging or complementing the out-of-Africa scenario? Dongwuxue Yanjiu (2015) 0.75
Neandertal versus Modern Human Dietary Responses to Climatic Fluctuations. PLoS One (2016) 0.75
working model of the deep relationships of diverse modern human genetic lineages outside of Africa. Mol Biol Evol (2017) 0.75
Mitochondrial DNA analysis of eneolithic trypillians from Ukraine reveals neolithic farming genetic roots. PLoS One (2017) 0.75
Archaeogenomic evidence reveals prehistoric matrilineal dynasty. Nat Commun (2017) 0.75
β-globin gene cluster haplotypes in ethnic minority populations of southwest China. Sci Rep (2017) 0.75
Extending the spectrum of DNA sequences retrieved from ancient bones and teeth. Genome Res (2017) 0.75
Genetic origins of the Minoans and Mycenaeans. Nature (2017) 0.75
Harnessing ancient genomes to study the history of human adaptation. Nat Rev Genet (2017) 0.75
AntCaller: an accurate variant caller incorporating ancient DNA damage. Mol Genet Genomics (2017) 0.75
Genetics: new tales from ancient DNA. Nat Methods (2017) 0.75
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics (2003) 130.85
MODELTEST: testing the model of DNA substitution. Bioinformatics (1998) 101.19
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nat Biotechnol (2009) 27.17
A draft sequence of the Neandertal genome. Science (2010) 19.55
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet (1999) 18.22
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet (2009) 9.16
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
A high-coverage genome sequence from an archaic Denisovan individual. Science (2012) 7.89
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell (2008) 6.98
Patterns of damage in genomic DNA sequences from a Neandertal. Proc Natl Acad Sci U S A (2007) 6.12
Targeted retrieval and analysis of five Neandertal mtDNA genomes. Science (2009) 5.79
Correcting for purifying selection: an improved human mitochondrial molecular clock. Am J Hum Genet (2009) 5.37
Ancient admixture in human history. Genetics (2012) 4.99
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform. Nucleic Acids Res (2011) 4.33
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS One (2010) 3.35
Evolutionary history of the COII/tRNALys intergenic 9 base pair deletion in human mitochondrial DNAs from the Pacific. Mol Biol Evol (1995) 3.10
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA. Nucleic Acids Res (2009) 3.09
A complete mtDNA genome of an early modern human from Kostenki, Russia. Curr Biol (2009) 3.09
Phylogeographic differentiation of mitochondrial DNA in Han Chinese. Am J Hum Genet (2002) 2.95
Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations. Hum Mol Genet (2006) 2.89
Polynesian genetic affinities with Southeast Asian populations as identified by mtDNA analysis. Am J Hum Genet (1995) 2.74
The archaeogenetics of Europe. Curr Biol (2010) 2.71
Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA. PLoS One (2012) 2.60
Targeted investigation of the Neandertal genome by array-based sequence capture. Science (2010) 2.49
The emerging limbs and twigs of the East Asian mtDNA tree. Mol Biol Evol (2002) 2.48
European early modern humans and the fate of the Neandertals. Proc Natl Acad Sci U S A (2007) 2.19
Length and GC-biases during sequencing library amplification: a comparison of various polymerase-buffer systems with ancient and modern DNA sequencing libraries. Biotechniques (2012) 1.99
Archaic human ancestry in East Asia. Proc Natl Acad Sci U S A (2011) 1.72
The human genetic history of the Americas: the final frontier. Curr Biol (2010) 1.58
Anatomically modern human in Southeast Asia (Laos) by 46 ka. Proc Natl Acad Sci U S A (2012) 1.43
The human genetic history of East Asia: weaving a complex tapestry. Curr Biol (2010) 1.26
Application and comparison of large-scale solution-based DNA capture-enrichment methods on ancient DNA. Sci Rep (2011) 1.25
An early modern human from Tianyuan Cave, Zhoukoudian, China. Proc Natl Acad Sci U S A (2007) 1.23
Large scale mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins. BMC Evol Biol (2011) 1.16
Analysis of human accelerated DNA regions using archaic hominin genomes. PLoS One (2012) 0.87
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet (2007) 20.22
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
Sequencing and analysis of Neanderthal genomic DNA. Science (2006) 8.06
Intra- and interspecific variation in primate gene expression patterns. Science (2002) 7.92
A high-coverage genome sequence from an archaic Denisovan individual. Science (2012) 7.89
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
The evolution of gene expression levels in mammalian organs. Nature (2011) 7.16
A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing. Cell (2008) 6.98
Analysis of one million base pairs of Neanderthal DNA. Nature (2006) 6.17
Patterns of damage in genomic DNA sequences from a Neandertal. Proc Natl Acad Sci U S A (2007) 6.12
Molecular evolution of FOXP2, a gene involved in speech and language. Nature (2002) 5.89
Genomewide comparison of DNA sequences between humans and chimpanzees. Am J Hum Genet (2002) 5.80
Targeted retrieval and analysis of five Neandertal mtDNA genomes. Science (2009) 5.79
Syphilis in China: results of a national surveillance programme. Lancet (2007) 5.76
Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science (2005) 5.68
Improved base calling for the Illumina Genome Analyzer using machine learning strategies. Genome Biol (2009) 5.64
A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature (2005) 5.51
Deep proteome and transcriptome mapping of a human cancer cell line. Mol Syst Biol (2011) 5.48
Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet (2005) 5.00
Evidence for gradients of human genetic diversity within and among continents. Genome Res (2004) 4.70
Early allelic selection in maize as revealed by ancient DNA. Science (2003) 4.38
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform. Nucleic Acids Res (2011) 4.33
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing. Nucleic Acids Res (2007) 4.26
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia. Nature (2010) 3.90
Accelerated evolution of conserved noncoding sequences in humans. Science (2006) 3.87
Regional patterns of gene expression in human and chimpanzee brains. Genome Res (2004) 3.84
No evidence of Neandertal mtDNA contribution to early modern humans. PLoS Biol (2004) 3.81
High-throughput DNA sequencing--concepts and limitations. Bioessays (2010) 3.77
Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae. Nature (2005) 3.74
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell (2009) 3.63
A neutral explanation for the correlation of diversity with recombination rates in humans. Am J Hum Genet (2003) 3.57
Targeted high-throughput sequencing of tagged nucleic acid samples. Nucleic Acids Res (2007) 3.56
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
Parallel tagged sequencing on the 454 platform. Nat Protoc (2008) 3.49
A neutral model of transcriptome evolution. PLoS Biol (2004) 3.44
Genomic sequencing of Pleistocene cave bears. Science (2005) 3.40
The derived FOXP2 variant of modern humans was shared with Neandertals. Curr Biol (2007) 3.39
Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS One (2010) 3.35
Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary. BMC Evol Biol (2008) 3.21
A draft genome of Yersinia pestis from victims of the Black Death. Nature (2011) 3.18
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA. Nucleic Acids Res (2009) 3.09
A complete mtDNA genome of an early modern human from Kostenki, Russia. Curr Biol (2009) 3.09
Evolution of primate gene expression. Nat Rev Genet (2006) 3.04
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells. Proc Natl Acad Sci U S A (2006) 3.03
PatMaN: rapid alignment of short sequences to large databases. Bioinformatics (2008) 2.77
Neanderthals in central Asia and Siberia. Nature (2007) 2.64
Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA. PLoS One (2012) 2.60
Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. PLoS Biol (2004) 2.56
Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution. Proc Natl Acad Sci U S A (2012) 2.54
The bonobo genome compared with the chimpanzee and human genomes. Nature (2012) 2.49
Targeted investigation of the Neandertal genome by array-based sequence capture. Science (2010) 2.49
The Neandertal genome and ancient DNA authenticity. EMBO J (2009) 2.46
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. Proc Natl Acad Sci U S A (2013) 2.45
Natural selection on the olfactory receptor gene family in humans and chimpanzees. Am J Hum Genet (2003) 2.44
Allele-specific transcript isoforms in human. FEBS Lett (2004) 2.38
The date of interbreeding between Neandertals and modern humans. PLoS Genet (2012) 2.35
Why do human diversity levels vary at a megabase scale? Genome Res (2005) 2.33
FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics (2007) 2.32
The 2007 Estimates for People at Risk for and Living With HIV in China: Progress and Challenges. J Acquir Immune Defic Syndr (2009) 2.27
Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Curr Biol (2008) 2.27
China's syphilis epidemic: a systematic review of seroprevalence studies. Sex Transm Dis (2006) 2.23
Human specific loss of olfactory receptor genes. Proc Natl Acad Sci U S A (2003) 2.23
Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol (2004) 2.22
Length and GC-biases during sequencing library amplification: a comparison of various polymerase-buffer systems with ancient and modern DNA sequencing libraries. Biotechniques (2012) 1.99
The Neandertal type site revisited: interdisciplinary investigations of skeletal remains from the Neander Valley, Germany. Proc Natl Acad Sci U S A (2002) 1.98
Towards BioDBcore: a community-defined information specification for biological databases. Nucleic Acids Res (2010) 1.97
Meningiomas in children and adolescents: a meta-analysis of individual patient data. Lancet Oncol (2011) 1.88
Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies. BMC Bioinformatics (2007) 1.84
The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine. Elife (2013) 1.84
Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol (2005) 1.82
Single-stranded DNA library preparation for the sequencing of ancient or damaged DNA. Nat Protoc (2013) 1.80
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proc Natl Acad Sci U S A (2003) 1.79
Transcriptional neoteny in the human brain. Proc Natl Acad Sci U S A (2009) 1.78
A top-level ontology of functions and its application in the Open Biomedical Ontologies. Bioinformatics (2006) 1.77
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A (2010) 1.76