Published in Adv Funct Mater on February 06, 2009
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs. Proc Natl Acad Sci U S A (2009) 2.25
Matrix nanotopography as a regulator of cell function. J Cell Biol (2012) 2.20
Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients. Biomaterials (2009) 1.53
Engineering microscale topographies to control the cell-substrate interface. Biomaterials (2012) 1.51
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. PLoS Biol (2012) 1.29
Synergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction media. Biomacromolecules (2010) 1.18
Salivary gland cell differentiation and organization on micropatterned PLGA nanofiber craters. Biomaterials (2013) 0.94
Pre-exposure of human adipose mesenchymal stem cells to soluble factors enhances their homing to brain cancer. Stem Cells Transl Med (2015) 0.86
Synergistic effects of matrix nanotopography and stiffness on vascular smooth muscle cell function. Tissue Eng Part A (2014) 0.84
Silk film topography directs collective epithelial cell migration. PLoS One (2012) 0.83
Glucose-6-phosphatase is a key metabolic regulator of glioblastoma invasion. Mol Cancer Res (2014) 0.82
Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective. Adv Mater (2013) 0.82
The taming of the cell: shape-memory nanopatterns direct cell orientation. Int J Nanomedicine (2014) 0.82
Rectified cell migration on saw-like micro-elastically patterned hydrogels with asymmetric gradient ratchet teeth. PLoS One (2013) 0.81
Micropatterning different cell types with microarray amplification of natural directional persistence. Adv Healthc Mater (2012) 0.81
Cells as active particles in asymmetric potentials: motility under external gradients. Biophys J (2014) 0.80
Temperature-responsive poly(ε-caprolactone) cell culture platform with dynamically tunable nano-roughness and elasticity for control of myoblast morphology. Int J Mol Sci (2014) 0.80
Selective modulation of cell response on engineered fractal silicon substrates. Sci Rep (2013) 0.79
Microfabricated nanotopological surfaces for study of adhesion-dependent cell mechanosensitivity. Small (2012) 0.79
Directed migration of cancer cells guided by the graded texture of the underlying matrix. Nat Mater (2016) 0.78
Nanostructures of designed geometry and functionality enable regulation of cellular signaling processes. Biochemistry (2012) 0.78
Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes. Cell Rep (2016) 0.77
Directional nanotopographic gradients: a high-throughput screening platform for cell contact guidance. Sci Rep (2015) 0.77
Emerging nanotechnology approaches in tissue engineering and regenerative medicine. Int J Nanomedicine (2014) 0.77
Topography design concept of a tissue engineering scaffold for controlling cell function and fate through actin cytoskeletal modulation. Tissue Eng Part B Rev (2014) 0.77
Charged nanomatrices as efficient platforms for modulating cell adhesion and shape. Tissue Eng Part C Methods (2012) 0.77
Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues. Biomaterials (2016) 0.76
Enhanced Bone Repair by Guided Osteoblast Recruitment Using Topographically Defined Implant. Tissue Eng Part A (2016) 0.76
Shape-memory surfaces for cell mechanobiology. Sci Technol Adv Mater (2015) 0.75
Method to study cell migration under uniaxial compression. Mol Biol Cell (2017) 0.75
Enhanced Directional Migration of Cancer Stem Cells in 3D Aligned Collagen Matrices. Biophys J (2017) 0.75
Motility-based cell sorting by planar cell chromatography. Anal Chem (2012) 0.75
Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151. Neoplasia (2016) 0.75
Calcific Aortic Valve Disease Is Associated with Layer-Specific Alterations in Collagen Architecture. PLoS One (2016) 0.75
Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization. Oncogene (2017) 0.75
Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients. ACS Appl Mater Interfaces (2017) 0.75
Cell migration: a physically integrated molecular process. Cell (1996) 23.49
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol (2005) 13.90
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater (2007) 6.86
Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell (2006) 6.02
Epithelial contact guidance on well-defined micro- and nanostructured substrates. J Cell Sci (2003) 3.79
Assembly and mechanosensory function of focal contacts. Curr Opin Cell Biol (2001) 3.73
Biomimetic materials for tissue engineering. Adv Drug Deliv Rev (2007) 3.34
Protein nanoarrays generated by dip-pen nanolithography. Science (2002) 2.95
Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials (2005) 2.94
Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates. Proc Natl Acad Sci U S A (2007) 2.47
Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells. J Cell Sci (2004) 2.31
Electrospun fine-textured scaffolds for heart tissue constructs. Biomaterials (2005) 1.79
Polymer-demixed nanotopography: control of fibroblast spreading and proliferation. Tissue Eng (2002) 1.59
The scale of substratum topographic features modulates proliferation of corneal epithelial cells and corneal fibroblasts. J Biomed Mater Res A (2006) 1.52
Tissue engineering and developmental biology: going biomimetic. Tissue Eng (2006) 1.34
Use of nanotopography to study mechanotransduction in fibroblasts--methods and perspectives. Eur J Cell Biol (2004) 1.30
Fabrication of nanostructures of polyethylene glycol for applications to protein adsorption and cell adhesion. Nanotechnology (2005) 1.30
Polyelectrolyte multilayer films of controlled stiffness modulate myoblast cells differentiation. Adv Funct Mater (2008) 1.20
Nano- and microscale holes modulate cell-substrate adhesion, cytoskeletal organization, and -beta1 integrin localization in SV40 human corneal epithelial cells. IEEE Trans Nanobioscience (2006) 1.15
A thermoresponsive, microtextured substrate for cell sheet engineering with defined structural organization. Biomaterials (2008) 1.14
Electrospun nanostructured scaffolds for tissue engineering applications. Nanomedicine (Lond) (2007) 1.04
The effect of topographic characteristics on cell migration velocity. Biomaterials (2006) 0.98
Guided three-dimensional growth of functional cardiomyocytes on polyethylene glycol nanostructures. Langmuir (2006) 0.94
Applications of biomimetic systems in drug delivery. Expert Opin Drug Deliv (2005) 0.89
Colloid lithography-induced polydimethylsiloxane microstructures and their application to cell patterning. Biotechnol Lett (2006) 0.80
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science (2002) 13.86
MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast. Nature (2007) 3.23
Information transduction capacity of noisy biochemical signaling networks. Science (2011) 2.95
A microfluidic chemostat for experiments with bacterial and yeast cells. Nat Methods (2005) 2.91
Dynamic properties of network motifs contribute to biological network organization. PLoS Biol (2005) 2.58
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip (2007) 2.30
Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs. Proc Natl Acad Sci U S A (2009) 2.25
Matrix nanotopography as a regulator of cell function. J Cell Biol (2012) 2.20
A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activity. Mol Syst Biol (2007) 2.13
A flexible and highly sensitive strain-gauge sensor using reversible interlocking of nanofibres. Nat Mater (2012) 2.09
Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses. J Biol Chem (2005) 2.08
Microengineered platforms for cell mechanobiology. Annu Rev Biomed Eng (2009) 2.02
Comment on "Oscillations in NF-kappaB signaling control the dynamics of gene expression". Science (2005) 1.79
Understanding NF-kappaB signaling via mathematical modeling. Mol Syst Biol (2008) 1.79
Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest (2012) 1.71
Modeling the cell's guidance system. Sci STKE (2002) 1.68
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells. Lab Chip (2009) 1.57
Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients. Biomaterials (2009) 1.53
Cellerator: extending a computer algebra system to include biochemical arrows for signal transduction simulations. Bioinformatics (2003) 1.53
Self-organization in high-density bacterial colonies: efficient crowd control. PLoS Biol (2007) 1.52
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr Biol (Camb) (2013) 1.52
Use of MR cell tracking to evaluate targeting of glial precursor cells to inflammatory tissue by exploiting the very late antigen-4 docking receptor. Radiology (2012) 1.51
Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells. Biomaterials (2013) 1.51
Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation. J Biol Chem (2013) 1.48
A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues. Lab Chip (2008) 1.46
GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs. Genes Dev (2003) 1.46
Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc Natl Acad Sci U S A (2009) 1.43
Human cerebrospinal fluid regulates proliferation and migration of stem cells through insulin-like growth factor-1. Stem Cells Dev (2015) 1.42
Diverse sensitivity thresholds in dynamic signaling responses by social amoebae. Sci Signal (2012) 1.41
Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit. Nat Chem Biol (2010) 1.35
A 3D Monte Carlo analysis of the role of dyadic space geometry in spark generation. Biophys J (2005) 1.34
Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays. Biomaterials (2010) 1.33
Multiple signaling pathways regulate yeast cell death during the response to mating pheromones. Mol Biol Cell (2006) 1.29
High content cell screening in a microfluidic device. Mol Cell Proteomics (2008) 1.29
Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. PLoS Biol (2012) 1.29
Nanotopography-guided tissue engineering and regenerative medicine. Adv Drug Deliv Rev (2012) 1.28
Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis. Curr Biol (2008) 1.27
Negative autoregulation by FAS mediates robust fetal erythropoiesis. PLoS Biol (2007) 1.25
Fine temporal control of the medium gas content and acidity and on-chip generation of series of oxygen concentrations for cell cultures. Lab Chip (2009) 1.25
Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. Proc Natl Acad Sci U S A (2011) 1.24
Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor. Proc Natl Acad Sci U S A (2010) 1.20
Lab-on-a-chip devices as an emerging platform for stem cell biology. Lab Chip (2010) 1.20
Synergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction media. Biomacromolecules (2010) 1.18
Subcellular-resolution delivery of a cytokine through precisely manipulated nanowires. Nat Nanotechnol (2010) 1.18
A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication. Sci Signal (2013) 1.17
Cell motility of neural stem cells is reduced after SPIO-labeling, which is mitigated after exocytosis. Magn Reson Med (2012) 1.16
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. Proc Natl Acad Sci U S A (2007) 1.15
Synthetic spatially graded Rac activation drives cell polarization and movement. Proc Natl Acad Sci U S A (2012) 1.14
Robust and sensitive control of a quorum-sensing circuit by two interlocked feedback loops. Mol Syst Biol (2008) 1.14
The systems biology of glycosylation. Chembiochem (2004) 1.09
Systems biology. How information theory handles cell signaling and uncertainty. Science (2012) 1.08
Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors. Sci Signal (2012) 1.08
Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration. Integr Biol (Camb) (2012) 1.08
Fluid-shear-stress-induced translocation of aquaporin-2 and reorganization of actin cytoskeleton in renal tubular epithelial cells. Integr Biol (Camb) (2010) 1.07
Biomimetic nanopatterns as enabling tools for analysis and control of live cells. Adv Mater (2010) 1.07
Pumpless, selective docking of yeast cells inside a microfluidic channel induced by receding meniscus. Lab Chip (2006) 1.05
Control of stem cell fate and function by engineering physical microenvironments. Integr Biol (Camb) (2012) 1.04
Patterning methods for polymers in cell and tissue engineering. Ann Biomed Eng (2012) 1.03
Modelling cell polarization driven by synthetic spatially graded Rac activation. PLoS Comput Biol (2012) 1.03
Analysis of pairwise cell interactions using an integrated dielectrophoretic-microfluidic system. Mol Syst Biol (2008) 0.98
Micro- and nanoengineering for stem cell biology: the promise with a caution. Trends Biotechnol (2011) 0.97
Adhesion assays of endothelial cells on nanopatterned surfaces within a microfluidic channel. Anal Chem (2010) 0.95
Two distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowth. PLoS One (2010) 0.95
Marginal zone B cells regulate antigen-specific T cell responses during infection. J Immunol (2012) 0.94
Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival. Clin Cancer Res (2014) 0.93
A cell-based model for quorum sensing in heterogeneous bacterial colonies. PLoS Comput Biol (2010) 0.92
Oscillatory signaling processes: the how, the why and the where. Curr Opin Genet Dev (2010) 0.92
Physical transfer of membrane and cytoplasmic components as a general mechanism of cell-cell communication. J Cell Sci (2009) 0.91
Analysis of preload-dependent reversible mechanical interlocking using beetle-inspired wing locking device. Langmuir (2011) 0.91
The application of information theory to biochemical signaling systems. Phys Biol (2012) 0.90
25th anniversary article: scalable multiscale patterned structures inspired by nature: the role of hierarchy. Adv Mater (2013) 0.89
Directional oil sliding surfaces with hierarchical anisotropic groove microstructures. Adv Mater (2013) 0.88
Using a microfluidic device for high-content analysis of cell signaling. Sci Signal (2009) 0.88
Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells. Mol Biosyst (2009) 0.88
Effect of orientation and density of nanotopography in dermal wound healing. Biomaterials (2012) 0.88
Nanotopography-guided migration of T cells. J Immunol (2012) 0.87
Scp160-dependent mRNA trafficking mediates pheromone gradient sensing and chemotropism in yeast. Cell Rep (2012) 0.87
A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction. Cell Cycle (2009) 0.87
Superimposed topographic and chemical cues synergistically guide neurite outgrowth. Lab Chip (2013) 0.86
Beetle-inspired bidirectional, asymmetric interlocking using geometry-tunable nanohairs. ACS Appl Mater Interfaces (2012) 0.85
Bioinspired reversible interlocker using regularly arrayed high aspect-ratio polymer fibers. Adv Mater (2011) 0.84
Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction. Cancer Res (2011) 0.84
Controlled mechanical fracture for fabricating microchannels with various size gradients. Lab Chip (2010) 0.84
Quantitative analysis of the combined effect of substrate rigidity and topographic guidance on cell morphology. IEEE Trans Nanobioscience (2011) 0.84
Pulsing cells: how fast is too fast? HFSP J (2008) 0.83
Wires in the soup: quantitative models of cell signaling. Trends Cell Biol (2008) 0.83
An integrated micro-electro-fluidic and protein arraying system for parallel analysis of cell responses to controlled microenvironments. Integr Biol (Camb) (2010) 0.83
Simple haptotactic gradient generation within a triangular microfluidic channel. Lab Chip (2010) 0.82
Models at the single cell level. Wiley Interdiscip Rev Syst Biol Med (2010) 0.81
Proteomics takes stem cell analyses to another level. Nat Biotechnol (2005) 0.80
Microfluidic technologies for studying synthetic circuits. Curr Opin Chem Biol (2012) 0.80
Synchronization of cell cycle of Saccharomyces cerevisiae by using a cell chip platform. Mol Cells (2011) 0.80
Hierarchical multilayer assembly of an ordered nanofibrous scaffold via thermal fusion bonding. Biofabrication (2014) 0.80