PubRank

James A Thomson

Author PubWeight™ 446.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Induced pluripotent stem cell lines derived from human somatic cells. Science 2007 71.50
2 Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009 34.27
3 Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 2009 24.41
4 Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009 17.16
5 The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol 2010 13.99
6 Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011 13.94
7 ProbeMatch: rapid alignment of oligonucleotides to genome allowing both gaps and mismatches. Bioinformatics 2009 13.34
8 Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2008 12.21
9 RNA-Seq gene expression estimation with read mapping uncertainty. Bioinformatics 2009 10.74
10 Somatic coding mutations in human induced pluripotent stem cells. Nature 2011 9.50
11 Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol 2003 9.15
12 Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 2010 8.74
13 Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 2007 8.59
14 Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol 2006 8.28
15 MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009 8.14
16 Feeder-independent culture of human embryonic stem cells. Nat Methods 2006 7.61
17 Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A 2010 7.31
18 Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res 2009 7.09
19 Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2005 6.37
20 BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol 2002 6.20
21 Chemically defined conditions for human iPSC derivation and culture. Nat Methods 2011 5.84
22 Homologous recombination in human embryonic stem cells. Nat Biotechnol 2003 5.77
23 Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ Res 2003 5.12
24 NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell 2008 4.88
25 EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments. Bioinformatics 2013 4.79
26 Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors. Proc Natl Acad Sci U S A 2003 4.67
27 Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood 2004 4.32
28 Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 2013 3.81
29 Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res 2007 3.56
30 Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci U S A 2013 3.53
31 Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 2005 3.38
32 Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 2008 2.99
33 Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res 2012 2.91
34 Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells 2005 2.78
35 Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. Cell Stem Cell 2010 2.69
36 Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell 2008 2.68
37 Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures. Blood 2006 2.66
38 High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am J Physiol Heart Circ Physiol 2011 2.65
39 A mesoderm-derived precursor for mesenchymal stem and endothelial cells. Cell Stem Cell 2010 2.58
40 Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J Anat 2002 2.52
41 High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors. Stem Cells 2003 2.42
42 Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proc Natl Acad Sci U S A 2011 2.41
43 Proteomic and phosphoproteomic comparison of human ES and iPS cells. Nat Methods 2011 2.39
44 Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells. Proc Natl Acad Sci U S A 2008 2.29
45 Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells 2011 2.26
46 Pluripotent stem cell lines. Genes Dev 2008 2.25
47 Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell 2008 2.21
48 Trophoblast differentiation in embryoid bodies derived from human embryonic stem cells. Endocrinology 2003 2.15
49 FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell 2011 2.11
50 A germ cell origin of embryonic stem cells? Development 2005 2.09
51 Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chem Biol 2007 2.08
52 Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing. Proc Natl Acad Sci U S A 2010 2.01
53 Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A 2009 1.95
54 Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood 2011 1.92
55 Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Protoc 2012 1.74
56 Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency. Cell Res 2011 1.72
57 Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme. J Virol 2003 1.57
58 Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS Genet 2007 1.51
59 A study of the relationships between oligonucleotide properties and hybridization signal intensities from NimbleGen microarray datasets. Nucleic Acids Res 2008 1.47
60 The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells. Biomaterials 2009 1.46
61 Identification of the hemogenic endothelial progenitor and its direct precursor in human pluripotent stem cell differentiation cultures. Cell Rep 2012 1.46
62 Evaluation of de novo transcriptome assemblies from RNA-Seq data. Genome Biol 2014 1.46
63 MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells. Stem Cells 2009 1.43
64 Arrays for the combinatorial exploration of cell adhesion. J Am Chem Soc 2004 1.41
65 Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway. J Immunol 2006 1.34
66 Functional endothelial cells derived from rhesus monkey embryonic stem cells. Blood 2003 1.25
67 Generation of red blood cells from human induced pluripotent stem cells. Stem Cells Dev 2011 1.25
68 The effects of adult guidance and peer discussion on the development of children's representations: evidence from the training of pedestrian skills. Br J Psychol 2005 1.24
69 Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood 2005 1.23
70 Dielectrophoretic separation of platelets from diluted whole blood in microfluidic channels. Electrophoresis 2008 1.20
71 Phosphorylation regulates human OCT4. Proc Natl Acad Sci U S A 2012 1.19
72 Human embryonic stem cells reprogram myeloid precursors following cell-cell fusion. Stem Cells 2005 1.17
73 LongSAGE profiling of nine human embryonic stem cell lines. Genome Biol 2007 1.15
74 Optical mapping discerns genome wide DNA methylation profiles. BMC Mol Biol 2008 1.14
75 Quantitative selection and parallel characterization of aptamers. Proc Natl Acad Sci U S A 2013 1.13
76 Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema. PLoS Comput Biol 2013 1.11
77 Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells. Blood 2011 1.08
78 Instant spectral assignment for advanced decision tree-driven mass spectrometry. Proc Natl Acad Sci U S A 2012 1.08
79 Differentiation of human embryonic stem cells occurs through symmetric cell division. Stem Cells 2005 1.04
80 Secreted proteoglycans directly mediate human embryonic stem cell-basic fibroblast growth factor 2 interactions critical for proliferation. Stem Cells 2008 1.01
81 Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. Stem Cells 2014 0.99
82 No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells. Stem Cells 2010 0.99
83 Single-round, multiplexed antibody mimetic design through mRNA display. Angew Chem Int Ed Engl 2012 0.98
84 A severe de novo methylation of episomal vectors by human ES cells. Biochem Biophys Res Commun 2006 0.98
85 Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. Stem Cell Rev 2015 0.98
86 Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets. Anal Chem 2012 0.98
87 Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells. Stem Cells 2012 0.98
88 Human ERas gene has an upstream premature polyadenylation signal that results in a truncated, noncoding transcript. Stem Cells 2005 0.96
89 Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagents. PLoS One 2013 0.95
90 Integrated module and gene-specific regulatory inference implicates upstream signaling networks. PLoS Comput Biol 2013 0.94
91 Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics. J Mol Biol 2004 0.92
92 Protein kinase C mediated extraembryonic endoderm differentiation of human embryonic stem cells. Stem Cells 2012 0.91
93 Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells 2007 0.91
94 TF-Cluster: a pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM). BMC Syst Biol 2011 0.89
95 Single read and paired end mRNA-Seq Illumina libraries from 10 nanograms total RNA. J Vis Exp 2011 0.88
96 The social cognitive determinants of offending drivers' speeding behaviour. Accid Anal Prev 2010 0.84
97 Pax3 and Tbx5 specify whether PDGFRα+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells. Stem Cells 2014 0.81
98 Human embryonic stem cell-derived cardiomyocytes: drug discovery and safety pharmacology. Expert Opin Drug Discov 2007 0.80
99 Array-based discovery of aptamer pairs. Anal Chem 2014 0.79
100 Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: implications for PEGylated arginine deiminase combination therapy. BMC Cancer 2014 0.79
101 Microarray analysis of stem cells and differentiation. Methods Enzymol 2006 0.78
102 A human pluripotent stem cell platform for assessing developmental neural toxicity screening. Stem Cell Res Ther 2013 0.78
103 Evidence that changes in social cognitions predict changes in self-reported driver behavior: Causal analyses of two-wave panel data. Accid Anal Prev 2012 0.78
104 Proteomics and pluripotency. Crit Rev Biochem Mol Biol 2011 0.77
105 A microarray analysis of the emergence of embryonic definitive hematopoiesis. Exp Hematol 2007 0.77
106 Efficient method for expressing transgenes in nonhuman primate embryos using a stable episomal vector. Mol Reprod Dev 2002 0.77
107 Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis. Biochemistry 2008 0.76
108 Gene targeting of human pluripotent stem cells by homologous recombination. Methods Mol Biol 2014 0.75