Autophagy in the lung.

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development. J Cell Mol Med (2013) 1.36

Autophagy in vascular disease. Proc Am Thorac Soc (2010) 1.16

Innate immunity to adenovirus. Hum Gene Ther (2014) 1.15

Construction of a computable network model for DNA damage, autophagy, cell death, and senescence. Bioinform Biol Insights (2013) 1.08

Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2012) 0.99

Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity. Pulm Pharmacol Ther (2010) 0.96

Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress. Toxicol Appl Pharmacol (2012) 0.95

Autophagy in inflammatory diseases. Int J Cell Biol (2011) 0.94

IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases. PLoS One (2014) 0.93

The role of microparticles in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2014) 0.89

Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy. Acta Pharmacol Sin (2012) 0.88

Host cell autophagy modulates early stages of adenovirus infections in airway epithelial cells. J Virol (2012) 0.87

Cigarette smoke-exposed neutrophils die unconventionally but are rapidly phagocytosed by macrophages. Cell Death Dis (2011) 0.86

Curcumin: updated molecular mechanisms and intervention targets in human lung cancer. Int J Mol Sci (2012) 0.85

Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice. Am J Physiol Lung Cell Mol Physiol (2014) 0.84

Cross talk between autophagy and apoptosis in pulmonary hypertension. Pulm Circ (2012) 0.84

Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulmonary mechanics. Toxicol Sci (2013) 0.82

Oxidative stress-induced autophagy: role in pulmonary toxicity. Toxicol Appl Pharmacol (2014) 0.81

Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis. Autophagy (2015) 0.81

Role of Nrf2 and Autophagy in Acute Lung Injury. Curr Pharmacol Rep (2016) 0.79

Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus. Am J Respir Cell Mol Biol (2014) 0.78

Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesis. Autophagy (2014) 0.78

Autophagy sensitivity of neuroendocrine lung tumor cells. Int J Oncol (2013) 0.78

Famine in the young and risk of later hospitalization for COPD and asthma. PLoS One (2013) 0.77

Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma. Korean J Intern Med (2015) 0.77

Effect of cigarette smoke and dexamethasone on Hsp72 system of alveolar epithelial cells. Cell Stress Chaperones (2010) 0.76

Therapeutic Effects of Resveratrol in a Mouse Model of LPS and Cigarette Smoke-Induced COPD. Inflammation (2016) 0.76

Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination. Cell Death Differ (2017) 0.75

MiR-15a/16 Regulates Apoptosis of Lung Epithelial Cells after Oxidative Stress. Mol Med (2016) 0.75

Cross-talk between apoptosis and autophagy in lung epithelial cell death. J Biochem Pharmacol Res (2014) 0.75

Assessment of expressions of Bcl-XL, b-FGF, Bmp-2, Caspase-3, PDGFR-α, Smad1 and TGF-β1 genes in a rat model of lung ischemia/reperfusion. Iran J Basic Med Sci (2016) 0.75

Pulmonary vascular diseases: in search of a hub among the spokes-an exercise in hypothesis generation. Pulm Circ (2013) 0.75

Time-dependent changes of autophagy and apoptosis in lipopolysaccharide-induced rat acute lung injury. Iran J Basic Med Sci (2016) 0.75

Seawater-drowning-induced acute lung injury: From molecular mechanisms to potential treatments. Exp Ther Med (2017) 0.75

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48

Autophagy in the pathogenesis of disease. Cell (2008) 34.68

Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83

Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol (2007) 33.06

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med (2001) 27.83

Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62

The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40

Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell (2004) 21.68

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55

Autophagy as a regulated pathway of cellular degradation. Science (2000) 17.27

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 16.67

The mammalian unfolded protein response. Annu Rev Biochem (2005) 16.31

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A (2003) 15.59

Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol (2007) 15.47

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2006) 15.14

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol (2000) 11.62

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science (2004) 10.77

Autophagy in cell death: an innocent convict? J Clin Invest (2005) 10.70

Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol (2005) 10.27

Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ (2004) 9.96

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J (2007) 9.65

Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol (2006) 8.89

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol (2004) 8.85

Autophagy: molecular machinery for self-eating. Cell Death Differ (2005) 8.46

The role of autophagy in cancer development and response to therapy. Nat Rev Cancer (2005) 8.18

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem (2008) 7.71

ERAD: the long road to destruction. Nat Cell Biol (2005) 7.46

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol (1998) 7.41

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell (2008) 7.32

Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature (2007) 7.21

Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol (2008) 6.78

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. J Biol Chem (2000) 6.71

The molecular machinery of autophagy: unanswered questions. J Cell Sci (2005) 6.67

Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 6.10

Autophagy, immunity, and microbial adaptations. Cell Host Microbe (2009) 5.84

Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity (2007) 5.36

Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci (2004) 5.19

The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci (2001) 5.18

Endoplasmic reticulum stress triggers autophagy. J Biol Chem (2006) 5.05

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol (2009) 4.95

Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci U S A (2006) 4.81

Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem (2005) 4.56

Toll-like receptors control autophagy. EMBO J (2008) 4.50

Cell biology: autophagy and cancer. Nature (2007) 4.40

The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell (2008) 4.25

Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87

Autophagy genes in immunity. Nat Immunol (2009) 3.76

Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem (2006) 3.74

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. J Cell Sci (2004) 3.66

Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol (1996) 3.49

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem (2002) 3.44

Two ubiquitin-like conjugation systems essential for autophagy. Semin Cell Dev Biol (2004) 3.04

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci (2007) 2.84

Oxidative stress and autophagy. Antioxid Redox Signal (2006) 2.79

Superoxide is the major reactive oxygen species regulating autophagy. Cell Death Differ (2009) 2.76

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One (2008) 2.67

MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J Biol Chem (2008) 2.63

Cell number and cell characteristics of the normal human lung. Am Rev Respir Dis (1982) 2.54

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ (2007) 2.51

Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest (1999) 2.44

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy (2008) 2.38

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem (2002) 2.37

Oxidant and antioxidant balance in the airways and airway diseases. Eur J Pharmacol (2006) 2.30

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res (2007) 2.22

Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments. J Cell Sci (2000) 2.10

Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J Biol Chem (2003) 2.06

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy (2007) 2.06

To die or not to die: that is the autophagic question. Curr Mol Med (2008) 2.05

PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol (2009) 2.00

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol (2008) 1.97

Programmed cell death (PCD). Apoptosis, autophagic PCD, or others? Ann N Y Acad Sci (2000) 1.93

Autophagy contributes to caspase-independent macrophage cell death. J Biol Chem (2006) 1.87

The ER stress pathway involving CHOP is activated in the lungs of LPS-treated mice. J Biochem (2005) 1.84

Suppression of growth and transformation and induction of apoptosis by EGR-1. Cancer Gene Ther (1998) 1.77

Acute lung injury and cell death: how many ways can cells die? Am J Physiol Lung Cell Mol Physiol (2008) 1.69

Autophagy, organelles and ageing. J Pathol (2007) 1.64

Alveolar cell death in hyperoxia-induced lung injury. Ann N Y Acad Sci (2003) 1.48

Functional significance and morphological characterization of starvation-induced autophagy in the adult heart. Am J Pathol (2009) 1.47

The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J (2007) 1.45

Science review: apoptosis in acute lung injury. Crit Care (2003) 1.45

Apoptosis in the lung: induction, clearance and detection. Am J Physiol Lung Cell Mol Physiol (2008) 1.29

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer (2008) 1.28

Autophagy in disease: a double-edged sword with therapeutic potential. Clin Sci (Lond) (2009) 1.26

Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells. J Pharmacol Exp Ther (2009) 1.23

Pulmonary ischaemia-reperfusion injury: role of apoptosis. Eur Respir J (2005) 1.23

ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation. Exp Cell Res (2003) 1.21

Endoplasmic reticulum stress. Ann N Y Acad Sci (2007) 1.18

Autophagy. Ann N Y Acad Sci (2005) 1.16

Novel roles for protein kinase Cdelta-dependent signaling pathways in acute hypoxic stress-induced autophagy. J Biol Chem (2008) 1.16

Synthesis and preliminary biological evaluation of novel pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as potential agents against A549 lung cancer cells. Bioorg Med Chem (2008) 1.16

Autophagy in neurodegeneration: two sides of the same coin. BMB Rep (2009) 1.07

Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism? Autophagy (2009) 1.03

PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis. Autophagy (2009) 1.02

Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival. Free Radic Biol Med (2007) 1.01

Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis. Am J Physiol Lung Cell Mol Physiol (2009) 0.97

Lung vascular cell heterogeneity: endothelium, smooth muscle, and fibroblasts. Proc Am Thorac Soc (2008) 0.96

Autophagy in lung cancer. Methods Enzymol (2009) 0.78

Knockdown of integrin beta4-induced autophagic cell death associated with P53 in A549 lung adenocarcinoma cells. FEBS J (2008) 0.78

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2010) 9.02

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev (2006) 7.76

Mechanisms of cell death in oxidative stress. Antioxid Redox Signal (2007) 3.33

Inflammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med (2012) 2.92

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis. J Exp Med (2006) 2.92

Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med (2006) 2.77

Autophagy in human health and disease. N Engl J Med (2013) 2.73

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One (2008) 2.67

Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury. Am J Respir Crit Care Med (2004) 2.60

Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A (2004) 2.42

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy (2008) 2.38

Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem (2009) 2.33

An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23

Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem (2002) 2.16

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med (2003) 2.15

Heme oxygenase-1: the "emerging molecule" has arrived. Am J Respir Cell Mol Biol (2002) 2.12

CO as a cellular signaling molecule. Annu Rev Pharmacol Toxicol (2006) 2.03

Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology (2010) 2.02

Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. Am J Respir Cell Mol Biol (2009) 1.94

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.93

Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J Biol Chem (2003) 1.83

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci U S A (2010) 1.82

Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus. Crit Care Med (2005) 1.73

Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. Am J Respir Cell Mol Biol (2006) 1.69

Carbon monoxide prevents ventilator-induced lung injury via caveolin-1. Crit Care Med (2009) 1.68

The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J Immunol (2009) 1.66

Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease. Am J Respir Cell Mol Biol (2006) 1.65

Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine. Gastroenterology (2003) 1.59

Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation. Circulation (2009) 1.58

Caveolae compartmentalization of heme oxygenase-1 in endothelial cells. FASEB J (2004) 1.54

Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. J Biol Chem (2006) 1.53

Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem (2002) 1.52

Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet (2009) 1.52

Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway. Am J Respir Cell Mol Biol (2005) 1.51

Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. Antioxid Redox Signal (2005) 1.49

Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol (2003) 1.47

Heme oxygenase-1: from bench to bedside. Am J Respir Crit Care Med (2005) 1.47

Gene expression profiling of target genes in ventilator-induced lung injury. Physiol Genomics (2006) 1.45

Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects. Am J Pathol (2003) 1.43

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Hum Mol Genet (2011) 1.42

Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system. Antioxid Redox Signal (2007) 1.41

Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. PLoS One (2008) 1.41

Carbon monoxide: to boldly go where NO has gone before. Sci STKE (2004) 1.40

Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress. Antioxid Redox Signal (2002) 1.40

Necrotic cell death in response to oxidant stress involves the activation of the apoptogenic caspase-8/bid pathway. J Biol Chem (2003) 1.39

Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis. J Immunol (2007) 1.39

Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med (2003) 1.39

Pathways of cell signaling in hyperoxia. Free Radic Biol Med (2003) 1.39

Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic Biol Med (2009) 1.38

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. Am J Respir Cell Mol Biol (2003) 1.36

Heme oxygenase-1 and carbon monoxide in pulmonary medicine. Respir Res (2003) 1.33

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. J Clin Invest (2013) 1.29

Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide. Proc Natl Acad Sci U S A (2005) 1.29

Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. J Immunol (2005) 1.28

The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease. PLoS One (2009) 1.28

Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med (2012) 1.27

Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages. Am J Respir Cell Mol Biol (2002) 1.27

Autophagy: a critical regulator of cellular metabolism and homeostasis. Mol Cells (2013) 1.24

Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1. Am J Respir Crit Care Med (2008) 1.23

Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. Am J Respir Cell Mol Biol (2011) 1.23

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest (2014) 1.23

Characterization of macroautophagic flux in vivo using a leupeptin-based assay. Autophagy (2011) 1.20

Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver. FASEB J (2004) 1.19

Protective effect of carbon monoxide in transplantation. J Cell Mol Med (2006) 1.19

Caveolin-1: a critical regulator of lung injury. Am J Physiol Lung Cell Mol Physiol (2010) 1.17

Carbon monoxide suppresses bleomycin-induced lung fibrosis. Am J Pathol (2005) 1.17

CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2. Am J Respir Cell Mol Biol (2006) 1.17

Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. Am J Pathol (2006) 1.17

Autophagy in vascular disease. Proc Am Thorac Soc (2010) 1.16

Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 1.16

Functional significance of apoptosis in chronic obstructive pulmonary disease. COPD (2007) 1.16

Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death. Am J Respir Cell Mol Biol (2011) 1.15

Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. Transl Res (2008) 1.14

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema. Am J Physiol Lung Cell Mol Physiol (2012) 1.13

Discovery of the gene signature for acute lung injury in patients with sepsis. Physiol Genomics (2009) 1.10

Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells. J Biol Chem (2004) 1.10

Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. Am J Respir Cell Mol Biol (2002) 1.09

Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts. Kidney Int (2008) 1.09

Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis. Arthritis Rheum (2006) 1.09

MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production. Am J Physiol Lung Cell Mol Physiol (2007) 1.09

TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells. Am J Physiol Lung Cell Mol Physiol (2002) 1.09

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. J Clin Invest (2015) 1.09

Autophagy in pulmonary diseases. Annu Rev Physiol (2011) 1.07

Heat-shock proteins: new keys to the development of cytoprotective therapies. Expert Opin Ther Targets (2006) 1.06

Inhaled carbon monoxide accelerates resolution of inflammation via unique proresolving mediator-heme oxygenase-1 circuits. J Immunol (2013) 1.06

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy (2011) 1.06

CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema. Am J Pathol (2008) 1.06

Carbon monoxide in sepsis. Antioxid Redox Signal (2007) 1.05

Carbon monoxide ameliorates renal cold ischemia-reperfusion injury with an upregulation of vascular endothelial growth factor by activation of hypoxia-inducible factor. Transplantation (2008) 1.05

Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism? Autophagy (2009) 1.03

Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study. Respir Res (2007) 1.03

Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. Expert Rev Respir Med (2010) 1.03

The emerging importance of autophagy in pulmonary diseases. Chest (2012) 1.03

Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. Am J Respir Cell Mol Biol (2008) 1.02

Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells. Am J Respir Cell Mol Biol (2005) 1.01

Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2012) 1.01

Mitochondria: commanders of innate immunity and disease? Curr Opin Immunol (2011) 1.01

Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol (2013) 1.01