Published in Stem Cells on April 01, 2010
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol (2015) 1.53
Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature (2012) 1.51
Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles. RNA (2011) 1.13
Reprogramming and development in nuclear transfer embryos and in interspecific systems. Curr Opin Genet Dev (2012) 1.02
Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation. Mol Cell Biol (2015) 0.88
Uncoupled embryonic and extra-embryonic tissues compromise blastocyst development after somatic cell nuclear transfer. PLoS One (2012) 0.86
Finding the niche for human somatic cell nuclear transfer. Nat Biotechnol (2011) 0.82
Stable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts. Stem Cells Dev (2014) 0.81
Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports (2016) 0.75
Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors. BMC Genomics (2016) 0.75
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
An oestrogen-receptor-alpha-bound human chromatin interactome. Nature (2009) 12.16
Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature (2007) 11.72
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Randomized trials stopped early for benefit: a systematic review. JAMA (2005) 8.43
Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med (2013) 7.40
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05
Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature (2006) 6.78
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
iPS cells produce viable mice through tetraploid complementation. Nature (2009) 6.51
A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis. Brief Bioinform (2012) 6.06
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol (2005) 5.99
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A (2009) 5.86
The impact of ocular blood flow in glaucoma. Prog Retin Eye Res (2002) 5.76
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science (2006) 5.52
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Predialysis nephrology care of older patients approaching end-stage renal disease. Arch Intern Med (2011) 5.11
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs). Genome Res (2007) 4.99
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature (2011) 4.92
Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev (2009) 4.69
Electrochemical energy storage for green grid. Chem Rev (2011) 4.48
Towards a transgenic model of Huntington's disease in a non-human primate. Nature (2008) 4.47
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell (2012) 4.18
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest (2010) 3.91
Body mass index and risk, age of onset, and survival in patients with pancreatic cancer. JAMA (2009) 3.86
Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death. JAMA (2010) 3.85
Epidemiological transition of stroke in China: twenty-one-year observational study from the Sino-MONICA-Beijing Project. Stroke (2008) 3.81
Arabidopsis HEN1: a genetic link between endogenous miRNA controlling development and siRNA controlling transgene silencing and virus resistance. Curr Biol (2003) 3.77
Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nat Biotechnol (2013) 3.65
Altitude and all-cause mortality in incident dialysis patients. JAMA (2009) 3.62
The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab (2010) 3.61
Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses. Am Heart J (2008) 3.52
The cell-cycle state of stem cells determines cell fate propensity. Cell (2013) 3.50
Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41
Longer- Versus Shorter-Duration Dual-Antiplatelet Therapy After Drug-Eluting Stent Placement: A Systematic Review and Meta-analysis. Ann Intern Med (2015) 3.41
Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial. CMAJ (2013) 3.25
HEN1 functions pleiotropically in Arabidopsis development and acts in C function in the flower. Development (2002) 3.24
Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis. BMJ (2009) 3.22
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology (2010) 3.16
Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions. Proc Natl Acad Sci U S A (2003) 3.02
Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis. JAMA (2011) 3.02
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Tube Formation in Nanoscale Materials. Nanoscale Res Lett (2008) 2.83
Complex and oriented ZnO nanostructures. Nat Mater (2003) 2.75
Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development. Nature (2011) 2.75
De novo quantitative bisulfite sequencing using the pyrosequencing technology. Anal Biochem (2004) 2.73
Comparative mortality risk of anemia management practices in incident hemodialysis patients. JAMA (2010) 2.71
Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning. Nat Genet (2007) 2.62
The increasing prevalence of atrial fibrillation among hemodialysis patients. J Am Soc Nephrol (2011) 2.61
Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies. Eur J Cancer (2011) 2.59
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J Biol Chem (2010) 2.59
Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 2.57
Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver. Hepatology (2007) 2.53
Challenges in the development of high protein concentration formulations. J Pharm Sci (2004) 2.52
Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Dev Biol (2007) 2.46
Primary fascial closure with mesh reinforcement is superior to bridged mesh repair for abdominal wall reconstruction. J Am Coll Surg (2013) 2.42
A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions. Dev Cell (2010) 2.40
Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu. Arch Neurol (2005) 2.39
NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses. PLoS Pathog (2009) 2.32
Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system. Cancer Res (2007) 2.30
Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors. J Clin Oncol (2011) 2.29
A systematic review of studies comparing health outcomes in Canada and the United States. Open Med (2007) 2.26
Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine. Proc Natl Acad Sci U S A (2002) 2.24
The H19 locus: role of an imprinted non-coding RNA in growth and development. Bioessays (2010) 2.23
Pluripotency factors regulate definitive endoderm specification through eomesodermin. Genes Dev (2011) 2.22
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol Cell (2003) 2.20
H19 acts as a trans regulator of the imprinted gene network controlling growth in mice. Development (2009) 2.16
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A (2010) 2.16
Effect of c-erbB2 overexpression on prognosis in osteosarcoma: evidence from eight studies. Tumour Biol (2014) 2.14
Reduced incidence of breast cancer-related lymphedema following mastectomy and breast reconstruction versus mastectomy alone. Plast Reconstr Surg (2012) 2.13
HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control. J Immunol (2010) 2.10
Lipofilling of the Breast Does Not Increase the Risk of Recurrence of Breast Cancer: A Matched Controlled Study. Plast Reconstr Surg (2016) 2.05
Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole. Infect Immun (2008) 2.05
Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas. Int J Urol (2012) 2.04
Patterns of second-line uterotonic use in a large sample of hospitalizations for childbirth in the United States: 2007-2011. Anesth Analg (2014) 2.04
Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg (2009) 2.04
Cortical thinning in persons at increased familial risk for major depression. Proc Natl Acad Sci U S A (2009) 2.04
Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease. J Cell Mol Med (2012) 1.99
Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans. Mol Biol Cell (2002) 1.98
The H19 locus acts in vivo as a tumor suppressor. Proc Natl Acad Sci U S A (2008) 1.98
Association between Agent Orange exposure and nonmelanotic invasive skin cancer: a pilot study. Plast Reconstr Surg (2014) 1.97
Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice. J Cereb Blood Flow Metab (2004) 1.97
Descending command systems for the initiation of locomotion in mammals. Brain Res Rev (2007) 1.97
Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog (2009) 1.96
Trends in the use and outcomes of implantable cardioverter-defibrillators in patients undergoing dialysis in the United States. Am J Kidney Dis (2011) 1.92
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol (2012) 1.91
Signal transduction during cold, salt, and drought stresses in plants. Mol Biol Rep (2011) 1.89
The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes. Cell Metab (2005) 1.89
Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis. Diabetes (2013) 1.87
Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review. BMJ (2012) 1.85