Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.

PubWeight™: 1.54‹?› | Rank: Top 4%

🔗 View Article (PMID 20029029)

Published in Sci Signal on December 22, 2009

Authors

Yonathan Lissanu Deribe1, Philipp Wild, Akhila Chandrashaker, Jasna Curak, Mirko H H Schmidt, Yannis Kalaidzidis, Natasa Milutinovic, Irina Kratchmarova, Lukas Buerkle, Michael J Fetchko, Philipp Schmidt, Saranya Kittanakom, Kevin R Brown, Igor Jurisica, Blagoy Blagoev, Marino Zerial, Igor Stagljar, Ivan Dikic

Author Affiliations

1: Institute of Biochemistry II and Cluster of Excellence Macromolecular Complexes, Goethe University School of Medicine, Frankfurt (Main), Germany.

Articles citing this

Feedback regulation of EGFR signalling: decision making by early and delayed loops. Nat Rev Mol Cell Biol (2011) 3.52

Post-translational modifications in signal integration. Nat Struct Mol Biol (2010) 2.23

Protein analysis by shotgun/bottom-up proteomics. Chem Rev (2013) 2.13

Spatial organization of transmembrane receptor signalling. EMBO J (2010) 2.03

Functional proteomics to dissect tyrosine kinase signalling pathways in cancer. Nat Rev Cancer (2010) 1.97

The tale of protein lysine acetylation in the cytoplasm. J Biomed Biotechnol (2010) 1.44

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation. Trends Cell Biol (2011) 1.43

Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene. Endocr Rev (2013) 1.40

Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast. Nat Protoc (2010) 1.30

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease. EMBO Mol Med (2012) 1.28

Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling. PLoS One (2013) 1.26

Regulation of CD133 by HDAC6 promotes β-catenin signaling to suppress cancer cell differentiation. Cell Rep (2012) 1.24

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol (2011) 1.19

The multiple-specificity landscape of modular peptide recognition domains. Mol Syst Biol (2011) 1.14

The secret life of kinases: functions beyond catalysis. Cell Commun Signal (2011) 1.13

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods (2014) 1.10

Beyond histone and deacetylase: an overview of cytoplasmic histone deacetylases and their nonhistone substrates. J Biomed Biotechnol (2010) 1.08

A novel GRK2/HDAC6 interaction modulates cell spreading and motility. EMBO J (2011) 1.08

HDAC inhibition decreases the expression of EGFR in colorectal cancer cells. PLoS One (2011) 1.05

Exploring the yeast acetylome using functional genomics. Cell (2012) 1.05

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. EMBO Mol Med (2012) 1.01

Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas. Br J Cancer (2013) 1.00

Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration. J Biol Chem (2013) 0.95

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity. PLoS One (2013) 0.94

Fundamentals of protein interaction network mapping. Mol Syst Biol (2015) 0.93

Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes. Elife (2015) 0.90

Epigenetics and autosomal dominant polycystic kidney disease. Biochim Biophys Acta (2010) 0.88

HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One (2012) 0.87

Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Oncogene (2013) 0.87

Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors. Biochem Biophys Res Commun (2010) 0.85

HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion. PLoS One (2013) 0.84

A Comprehensive Membrane Interactome Mapping of Sho1p Reveals Fps1p as a Novel Key Player in the Regulation of the HOG Pathway in S. cerevisiae. J Mol Biol (2015) 0.81

Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression. EMBO Mol Med (2015) 0.79

Sulfiredoxin Promotes Colorectal Cancer Cell Invasion and Metastasis through a Novel Mechanism of Enhancing EGFR Signaling. Mol Cancer Res (2015) 0.79

Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer. Oncotarget (2015) 0.77

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation. PLoS One (2015) 0.77

EGFR signaling in renal fibrosis. Kidney Int Suppl (2011) (2014) 0.77

On mammary gland growth factors: roles in normal development and in cancer. Cold Spring Harb Perspect Biol (2012) 0.77

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. Kidney Int (2016) 0.77

A genetically encoded alkyne directs palladium-mediated protein labeling on live mammalian cell surface. ACS Chem Biol (2014) 0.76

Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling. PLoS One (2014) 0.76

CK2 as anti-stress factor. Commun Integr Biol (2012) 0.76

Cigarette Smoke Disrupted Lung Endothelial Barrier Integrity and Increased Susceptibility to Acute Lung Injury via Histone Deacetylase 6. Am J Respir Cell Mol Biol (2016) 0.75

Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Mol Syst Biol (2017) 0.75

EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation. BMC Cell Biol (2015) 0.75

Histone deacetylase 6 associates with ribosomes and regulates de novo protein translation during arsenite stress. Toxicol Sci (2012) 0.75

G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis. EBioMedicine (2016) 0.75

aPKC phosphorylation of HDAC6 results in increased deacetylation activity. PLoS One (2015) 0.75

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation. Front Pharmacol (2017) 0.75

Articles by these authors

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics (2002) 30.58

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell (2006) 20.92

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med (2008) 10.12

Rab conversion as a mechanism of progression from early to late endosomes. Cell (2005) 8.96

A role for ubiquitin in selective autophagy. Mol Cell (2009) 8.43

Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell (2009) 6.88

Online predicted human interaction database. Bioinformatics (2005) 6.83

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series. EMBO Rep (2008) 6.21

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell (2009) 5.76

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science (2005) 5.75

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature (2005) 5.72

Nix is a selective autophagy receptor for mitochondrial clearance. EMBO Rep (2009) 5.52

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science (2011) 5.46

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat Cell Biol (2003) 5.43

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature (2005) 5.30

Stem cell gene expression programs influence clinical outcome in human leukemia. Nat Med (2011) 5.24

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat Biotechnol (2004) 5.22

High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21

New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12

Systems survey of endocytosis by multiparametric image analysis. Nature (2010) 5.03

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85

Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature (2008) 4.76

Ubiquitylation and cell signaling. EMBO J (2005) 4.65

Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol (2006) 4.55

Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. J Clin Oncol (2010) 4.19

Not just a sink: endosomes in control of signal transduction. Curr Opin Cell Biol (2004) 4.15

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature (2011) 4.14

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature (2002) 3.99

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science (2011) 3.89

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. Nature (2006) 3.89

Identification of the switch in early-to-late endosome transition. Cell (2010) 3.86

Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res (2002) 3.68

Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes. Nat Cell Biol (2002) 3.65

Specification of SUMO1- and SUMO2-interacting motifs. J Biol Chem (2006) 3.59

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. Nat Biotechnol (2003) 3.54

Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation. Science (2005) 3.37

Distinct monoubiquitin signals in receptor endocytosis. Trends Biochem Sci (2003) 3.37

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell (2008) 3.37

Caveolin-stabilized membrane domains as multifunctional transport and sorting devices in endocytic membrane traffic. Cell (2004) 3.30

Targeting the ubiquitin system in cancer therapy. Nature (2009) 3.27

The Cbl interactome and its functions. Nat Rev Mol Cell Biol (2005) 3.27

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms. Mol Ther (2010) 3.26

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium. Nat Methods (2012) 3.17

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature (2008) 3.11

Regulation of ubiquitin-binding proteins by monoubiquitination. Nat Cell Biol (2006) 2.99

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol (2005) 2.97

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis. Nat Rev Cancer (2006) 2.90

Prognostic gene signatures for non-small-cell lung cancer. Proc Natl Acad Sci U S A (2009) 2.84

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape. Nat Biotechnol (2013) 2.81

Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res (2010) 2.79

Evaluation of linguistic features useful in extraction of interactions from PubMed; application to annotating known, high-throughput and predicted interactions in I2D. Bioinformatics (2009) 2.78

E3-independent monoubiquitination of ubiquitin-binding proteins. Mol Cell (2007) 2.77

Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae. Nature (2005) 2.75

Kinetics of morphogen gradient formation. Science (2007) 2.73

Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. Cell (2005) 2.67

Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction. JAMA (2011) 2.61

The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol (2004) 2.59

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal (2011) 2.54

Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annu Rev Biochem (2012) 2.53

Properties of 13C-substituted arginine in stable isotope labeling by amino acids in cell culture (SILAC). J Proteome Res (2003) 2.51

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res (2006) 2.50

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature (2011) 2.47

Unequal evolutionary conservation of human protein interactions in interologous networks. Genome Biol (2007) 2.45

Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest (2009) 2.43

MSQuant, an open source platform for mass spectrometry-based quantitative proteomics. J Proteome Res (2010) 2.40

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto. Bioinformatics (2009) 2.34

Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr Opin Cell Biol (2007) 2.30

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes. Nature (2009) 2.23

Post-translational modifications in signal integration. Nat Struct Mol Biol (2010) 2.23

mRNA transcript quantification in archival samples using multiplexed, color-coded probes. BMC Biotechnol (2011) 2.20

Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem (2005) 2.15

The spatial and temporal organization of ubiquitin networks. Nat Rev Mol Cell Biol (2011) 2.15

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle (2009) 2.12

Dissection of the insulin signaling pathway via quantitative phosphoproteomics. Proc Natl Acad Sci U S A (2008) 2.11

Three-gene prognostic classifier for early-stage non small-cell lung cancer. J Clin Oncol (2007) 2.10

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nat Cell Biol (2011) 2.07

Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol (2008) 2.05

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae. Nature (2012) 2.05

Spatial organization of transmembrane receptor signalling. EMBO J (2010) 2.03

Large-scale identification of yeast integral membrane protein interactions. Proc Natl Acad Sci U S A (2005) 2.03

Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage. Mol Cell Biol (2006) 2.02

Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum Mol Genet (2009) 2.00