Published in BMC Bioinformatics on March 11, 2010
Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule. BMC Pharmacol (2010) 0.86
A web server for predicting inhibitors against bacterial target GlmU protein. BMC Pharmacol (2011) 0.85
Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv). Chem Cent J (2013) 0.82
DrugMint: a webserver for predicting and designing of drug-like molecules. Biol Direct (2013) 0.82
QSAR-based models for designing quinazoline/imidazothiazoles/pyrazolopyrimidines based inhibitors against wild and mutant EGFR. PLoS One (2014) 0.79
Prioritization of anticancer drugs against a cancer using genomic features of cancer cells: A step towards personalized medicine. Sci Rep (2016) 0.75
An in silico platform for predicting, screening and designing of antihypertensive peptides. Sci Rep (2015) 0.75
Beware of q2! J Mol Graph Model (2002) 5.13
Bacterial resistance: origins, epidemiology, and impact. Clin Infect Dis (2003) 3.42
Changing patterns of infectious disease. Nature (2000) 3.21
Similarity-based virtual screening using 2D fingerprints. Drug Discov Today (2006) 2.72
Structure-based virtual screening: an overview. Drug Discov Today (2002) 2.70
Computer-based de novo design of drug-like molecules. Nat Rev Drug Discov (2005) 1.83
The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. J Mol Biol (1995) 1.70
Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst (2007) 1.69
Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy. Biochemistry (1997) 1.62
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr D Biol Crystallogr (2005) 1.47
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J (2008) 1.46
Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins (2006) 1.40
Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J (2006) 1.37
Active learning with support vector machines in the drug discovery process. J Chem Inf Comput Sci (2003) 1.31
Escherichia coli dihydrodipicolinate synthase. Identification of the active site and crystallization. Biochem J (1992) 1.28
Economic impact of antimicrobial resistance. Emerg Infect Dis (2001) 1.27
Bacterial diaminopimelate metabolism as a target for antibiotic design. Bioorg Med Chem (2000) 1.26
Dihydrodipicolinate synthase from Escherichia coli: pH dependent changes in the kinetic mechanism and kinetic mechanism of allosteric inhibition by L-lysine. Biochemistry (1997) 1.10
CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site. J Med Chem (2002) 0.99
Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.99
Application of validated QSAR models of D1 dopaminergic antagonists for database mining. J Med Chem (2005) 0.98
A support vector machines approach for virtual screening of active compounds of single and multiple mechanisms from large libraries at an improved hit-rate and enrichment factor. J Mol Graph Model (2007) 0.93
Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate. Bioorg Med Chem Lett (2005) 0.93
A combined approach of docking and 3D QSAR study of beta-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors. Bioorg Med Chem (2005) 0.85
Support vector machine for SAR/QSAR of phenethyl-amines. Acta Pharmacol Sin (2007) 0.84
Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive. Bioorg Med Chem (2005) 0.83
Computational studies of COX-2 inhibitors: 3D-QSAR and docking. Bioorg Med Chem (2004) 0.79
QSAR studies of paeonol analogues for inhibition of platelet aggregation. Bioorg Med Chem (2005) 0.78
Improving QSAR models for the biological activity of HIV Reverse Transcriptase inhibitors: Aspects of outlier detection and uninformative variable elimination. Talanta (2005) 0.78
Bcipep: a database of B-cell epitopes. BMC Genomics (2005) 2.27
Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search. J Biol Chem (2005) 1.85
Biotechnological aspects of chitinolytic enzymes: a review. Appl Microbiol Biotechnol (2006) 1.78
Identification of DNA-binding proteins using support vector machines and evolutionary profiles. BMC Bioinformatics (2007) 1.59
Prediction of mitochondrial proteins using support vector machine and hidden Markov model. J Biol Chem (2005) 1.42
MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes. BMC Res Notes (2009) 1.41
Classification of nuclear receptors based on amino acid composition and dipeptide composition. J Biol Chem (2004) 1.36
Enhanced production of pectinase by Bacillus sp. DT7 using solid state fermentation. Bioresour Technol (2003) 1.35
Improved method for linear B-cell epitope prediction using antigen's primary sequence. PLoS One (2013) 1.34
In silico platform for prediction of N-, O- and C-glycosites in eukaryotic protein sequences. PLoS One (2013) 1.29
In silico approaches for designing highly effective cell penetrating peptides. J Transl Med (2013) 1.17
AntiBP2: improved version of antibacterial peptide prediction. BMC Bioinformatics (2010) 1.15
Identification of ATP binding residues of a protein from its primary sequence. BMC Bioinformatics (2009) 1.15
SVM based prediction of RNA-binding proteins using binding residues and evolutionary information. J Mol Recognit (2011) 1.13
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database. Nucleic Acids Res (2012) 1.11
Branching of the p-nitrophenol (PNP) degradation pathway in burkholderia sp. Strain SJ98: Evidences from genetic characterization of PNP gene cluster. AMB Express (2012) 1.10
TumorHoPe: a database of tumor homing peptides. PLoS One (2012) 1.07
ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins. BMC Bioinformatics (2008) 1.07
Identification of NAD interacting residues in proteins. BMC Bioinformatics (2010) 1.07
Prediction methods for B-cell epitopes. Methods Mol Biol (2007) 1.05
Production of cellulases from Aspergillus niger NS-2 in solid state fermentation on agricultural and kitchen waste residues. Waste Manag (2012) 1.04
In silico approach for predicting toxicity of peptides and proteins. PLoS One (2013) 1.02
Prediction of polyadenylation signals in human DNA sequences using nucleotide frequencies. In Silico Biol (2009) 1.00
Chitinase production in solid-state fermentation by Enterobacter sp. NRG4 using statistical experimental design. Curr Microbiol (2005) 1.00
Prediction of guide strand of microRNAs from its sequence and secondary structure. BMC Bioinformatics (2009) 0.99
Prediction of GTP interacting residues, dipeptides and tripeptides in a protein from its evolutionary information. BMC Bioinformatics (2010) 0.99
Application of machine learning techniques in predicting MHC binders. Methods Mol Biol (2007) 0.99
BTXpred: prediction of bacterial toxins. In Silico Biol (2007) 0.98
Prediction and classification of ncRNAs using structural information. BMC Genomics (2014) 0.97
Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides. Nucleic Acids Res (2013) 0.96
RSLpred: an integrative system for predicting subcellular localization of rice proteins combining compositional and evolutionary information. Proteomics (2009) 0.96
Prediction of FAD interacting residues in a protein from its primary sequence using evolutionary information. BMC Bioinformatics (2010) 0.96
CancerDR: cancer drug resistance database. Sci Rep (2013) 0.96
Machine learning techniques in disease forecasting: a case study on rice blast prediction. BMC Bioinformatics (2006) 0.95
Protective efficacy of probiotic alone or in conjunction with a prebiotic in Salmonella-induced liver damage. FEMS Microbiol Ecol (2009) 0.95
GlycoPP: a webserver for prediction of N- and O-glycosites in prokaryotic protein sequences. PLoS One (2012) 0.93
A machine learning based method for the prediction of secretory proteins using amino acid composition, their order and similarity-search. In Silico Biol (2008) 0.93
Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa. Int J Biol Macromol (2011) 0.93
Computational approach for designing tumor homing peptides. Sci Rep (2013) 0.92
Identification of mannose interacting residues using local composition. PLoS One (2011) 0.92
Isolation and identification of phosphate solubilizing bacteria able to enhance the growth and aloin-A biosynthesis of Aloe barbadensis Miller. Microbiol Res (2012) 0.91
HIVsirDB: a database of HIV inhibiting siRNAs. PLoS One (2011) 0.91
Prediction of neurotoxins based on their function and source. In Silico Biol (2007) 0.90
Designing of highly effective complementary and mismatch siRNAs for silencing a gene. PLoS One (2011) 0.90
Prediction of nuclear proteins using SVM and HMM models. BMC Bioinformatics (2009) 0.90
PRRDB: a comprehensive database of pattern-recognition receptors and their ligands. BMC Genomics (2008) 0.90
ccPDB: compilation and creation of data sets from Protein Data Bank. Nucleic Acids Res (2011) 0.90
CyclinPred: a SVM-based method for predicting cyclin protein sequences. PLoS One (2008) 0.89
A simple approach for predicting protein-protein interactions. Curr Protein Pept Sci (2010) 0.88
PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors. BMC Bioinformatics (2013) 0.88
Hmrbase: a database of hormones and their receptors. BMC Genomics (2009) 0.88
Phytomodulatory potentials of Aloe vera against Salmonella OmpR-mediated inflammation. Phytother Res (2008) 0.87
OxDBase: a database of oxygenases involved in biodegradation. BMC Res Notes (2009) 0.87
COPid: composition based protein identification. In Silico Biol (2008) 0.87
Prediction and classification of aminoacyl tRNA synthetases using PROSITE domains. BMC Genomics (2010) 0.86
Designing of interferon-gamma inducing MHC class-II binders. Biol Direct (2013) 0.86
ProGlycProt: a repository of experimentally characterized prokaryotic glycoproteins. Nucleic Acids Res (2011) 0.85
Peptidoglycan biosynthesis machinery: a rich source of drug targets. Crit Rev Biotechnol (2010) 0.85
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis. BMC Bioinformatics (2010) 0.85
Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.85
A web server for predicting inhibitors against bacterial target GlmU protein. BMC Pharmacol (2011) 0.85
Production of N-acetylglucosamine using recombinant chitinolytic enzymes. Indian J Microbiol (2011) 0.85
Novel in silico tools for designing peptide-based subunit vaccines and immunotherapeutics. Brief Bioinform (2017) 0.84
Epidemiology and molecular characterization of vancomycin resistant Enterococci isolates in India. Scand J Infect Dis (2007) 0.84
Open source software and web services for designing therapeutic molecules. Curr Top Med Chem (2013) 0.84
Bridging innate and adaptive antitumor immunity targeting glycans. J Biomed Biotechnol (2010) 0.84
Current antibiogram and clonal relatedness among drug-resistant Salmonella enterica serovar Typhi in Northern India. Microb Drug Resist (2013) 0.84
Hybrid approach for predicting coreceptor used by HIV-1 from its V3 loop amino acid sequence. PLoS One (2013) 0.82
Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv). Chem Cent J (2013) 0.82
Evaluation of in-house loop-mediated isothermal amplification (LAMP) assay for rapid diagnosis of M. tuberculosis in pulmonary specimens. J Clin Lab Anal (2013) 0.82
Searching and mapping of B-cell epitopes in Bcipep database. Methods Mol Biol (2007) 0.82
Development and evaluation of a multiplex polymerase chain reaction for the detection of Mycobacterium tuberculosis from pulmonary specimens. Scand J Infect Dis (2012) 0.81
Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv. Acta Crystallogr D Biol Crystallogr (2012) 0.81
Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information. BMC Bioinformatics (2013) 0.80
Peptide toxicity prediction. Methods Mol Biol (2015) 0.79
In silico models for B-cell epitope recognition and signaling. Methods Mol Biol (2013) 0.79
BIAdb: a curated database of benzylisoquinoline alkaloids. BMC Pharmacol (2010) 0.79
Immunological characterization of recombinant Salmonella enterica serovar Typhi FliC protein expressed in Escherichia coli. AMB Express (2012) 0.79
PolysacDB: a database of microbial polysaccharide antigens and their antibodies. PLoS One (2012) 0.78
UDP-N-acetylglucosamine enolpyruvyl transferase as a potential target for antibacterial chemotherapy: recent developments. Appl Microbiol Biotechnol (2011) 0.78
Two new Aromatic Glycosides from a Soil Bacterium Burkholderia gladioli OR1. Nat Prod Commun (2016) 0.77
In silico platform for predicting and initiating β-turns in a protein at desired locations. Proteins (2015) 0.77
Identification of druggable targets for Acinetobacter baumannii via subtractive genomics and plausible inhibitors for MurA and MurB. Appl Biochem Biotechnol (2013) 0.77
Development of a model webserver for breed identification using microsatellite DNA marker. BMC Genet (2013) 0.77
Searching and mapping of T-cell epitopes, MHC binders, and TAP binders. Methods Mol Biol (2007) 0.76
Predicting virulence factors of immunological interest. Methods Mol Biol (2007) 0.76
Intrinsic contributions of polar amino acid residues toward thermal stability of an ABC-ATPase of mesophilic origin. Protein Sci (2003) 0.75
Antimicrobial susceptibility pattern of Burkholderia cepacia complex & Stenotrophomonas maltophilia over six years (2007-2012). Indian J Med Res (2015) 0.75
Heat stable antimicrobial activity of Burkholderia gladioli OR1 against clinical drug resistant isolates. Indian J Med Res (2012) 0.75
Demonstration of a new biosensing concept for immunodiagnostic applications based on change in surface conductance of antibodies after biomolecular interactions. J Zhejiang Univ Sci B (2006) 0.75
Searching haptens, carrier proteins, and anti-hapten antibodies. Methods Mol Biol (2007) 0.75
Nosocomial urinary tract infection due to Leuconostoc mesenteroides at a tertiary care centre in north India. Indian J Med Res (2005) 0.75
Genetic polymorphisms among Mycobacterium tuberculosis isolates from patients with pulmonary tuberculosis in northern India. Southeast Asian J Trop Med Public Health (2012) 0.75
Highly thermostable and pH-stable cellulases from Aspergillus niger NS-2: properties and application for cellulose hydrolysis. Appl Biochem Biotechnol (2013) 0.75