Published in Sci Rep on January 01, 2013
Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes. Nucleic Acids Res (2014) 0.94
PCMdb: pancreatic cancer methylation database. Sci Rep (2014) 0.90
Herceptin resistance database for understanding mechanism of resistance in breast cancer patients. Sci Rep (2014) 0.87
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening. Genome Med (2014) 0.82
CancerHSP: anticancer herbs database of systems pharmacology. Sci Rep (2015) 0.82
An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent. Mar Drugs (2014) 0.81
Computationally unraveling how ceritinib overcomes drug-resistance mutations in ALK-rearranged lung cancer. J Mol Model (2015) 0.81
Designing of promiscuous inhibitors against pancreatic cancer cell lines. Sci Rep (2014) 0.78
Ranking novel cancer driving synthetic lethal gene pairs using TCGA data. Oncotarget (2016) 0.77
Atomistic insights into the lung cancer-associated L755P mutation in HER2 resistance to lapatinib: a molecular dynamics study. J Mol Model (2015) 0.77
Biomolecular Network-Based Synergistic Drug Combination Discovery. Biomed Res Int (2016) 0.75
CancerResource-updated database of cancer-relevant proteins, mutations and interacting drugs. Nucleic Acids Res (2015) 0.75
Human cancer databases (review). Oncol Rep (2014) 0.75
GEAR: A database of Genomic Elements Associated with drug Resistance. Sci Rep (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers (1983) 99.69
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature (2012) 31.78
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature (2012) 20.47
Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature (2012) 15.91
Tablet--next generation sequence assembly visualization. Bioinformatics (2009) 11.75
Human immunodeficiency virus reverse transcriptase and protease sequence database. Nucleic Acids Res (2003) 10.50
Comparative protein structure modeling using Modeller. Curr Protoc Bioinformatics (2006) 8.72
HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment. Nat Methods (2011) 6.06
AUGUSTUS: a web server for gene finding in eukaryotes. Nucleic Acids Res (2004) 5.53
TTD: Therapeutic Target Database. Nucleic Acids Res (2002) 4.91
MUSTANG: a multiple structural alignment algorithm. Proteins (2006) 4.69
Cancer genomics: from discovery science to personalized medicine. Nat Med (2011) 3.66
Epigenetic changes in cancer. APMIS (2007) 1.96
The calibrated population resistance tool: standardized genotypic estimation of transmitted HIV-1 drug resistance. Bioinformatics (2009) 1.80
Personalized medicine in lung cancer: what we need to know. Nat Rev Clin Oncol (2011) 1.65
PEPstr: a de novo method for tertiary structure prediction of small bioactive peptides. Protein Pept Lett (2007) 1.57
Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation. Cancer Res (2011) 1.40
Cause and consequences of genetic and epigenetic alterations in human cancer. Curr Genomics (2008) 1.31
The HIVdb system for HIV-1 genotypic resistance interpretation. Intervirology (2012) 1.26
Managing drug resistance in cancer: lessons from HIV therapy. Nat Rev Cancer (2012) 1.19
Role of nanobiotechnology in developing personalized medicine for cancer. Technol Cancer Res Treat (2005) 1.12
Java bioinformatics analysis web services for multiple sequence alignment--JABAWS:MSA. Bioinformatics (2011) 1.00
Implications of personalized medicine--perspective from a cancer center. Nat Rev Clin Oncol (2011) 0.96
The pharmacology of HIV drug resistance. Am J Pharm Educ (2006) 0.90
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 23.97
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science (2002) 5.47
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell (2006) 5.39
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity (2006) 3.41
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat Immunol (2003) 3.24
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med (2002) 3.16
IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J Immunol (2005) 3.15
Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity (2002) 2.99
Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity (2008) 2.72
Assembling a gene regulatory network for specification of the B cell fate. Dev Cell (2004) 2.46
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol (2008) 2.40
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (2012) 2.30
Bcipep: a database of B-cell epitopes. BMC Genomics (2005) 2.27
Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature (2012) 2.25
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell (2012) 2.20
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol (2008) 2.19
IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev (2003) 2.12
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity (2002) 2.10
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol (2011) 1.95
Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search. J Biol Chem (2005) 1.85
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol (2004) 1.82
Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol (2008) 1.78
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nat Immunol (2005) 1.76
A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol (2006) 1.67
Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol Cell (2002) 1.64
Identification of DNA-binding proteins using support vector machines and evolutionary profiles. BMC Bioinformatics (2007) 1.59
A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity (2009) 1.55
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity (2013) 1.52
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nat Immunol (2009) 1.48
Can olanzapine be implicated in causing serotonin syndrome? Psychiatry Clin Neurosci (2002) 1.44
Prediction of mitochondrial proteins using support vector machine and hidden Markov model. J Biol Chem (2005) 1.42
MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes. BMC Res Notes (2009) 1.41
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol (2011) 1.41
Classification of nuclear receptors based on amino acid composition and dipeptide composition. J Biol Chem (2004) 1.36
Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol (2012) 1.35
The 2003 outbreak of Dengue fever in Delhi, India. Southeast Asian J Trop Med Public Health (2005) 1.35
Improved method for linear B-cell epitope prediction using antigen's primary sequence. PLoS One (2013) 1.34
In silico platform for prediction of N-, O- and C-glycosites in eukaryotic protein sequences. PLoS One (2013) 1.29
Genetic networks that regulate B lymphopoiesis. Curr Opin Hematol (2005) 1.26
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol (2013) 1.24
CPPsite: a curated database of cell penetrating peptides. Database (Oxford) (2012) 1.21
IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood (2012) 1.19
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol (2012) 1.18
In silico approaches for designing highly effective cell penetrating peptides. J Transl Med (2013) 1.17
An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol Syst Biol (2011) 1.17
Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis. Mol Biol Cell (2014) 1.16
AntiBP2: improved version of antibacterial peptide prediction. BMC Bioinformatics (2010) 1.15
Identification of ATP binding residues of a protein from its primary sequence. BMC Bioinformatics (2009) 1.15
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol (2008) 1.14
POU/TBP cooperativity: a mechanism for enhancer action from a distance. Mol Cell (2002) 1.14
SVM based prediction of RNA-binding proteins using binding residues and evolutionary information. J Mol Recognit (2011) 1.13
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med (2010) 1.12
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database. Nucleic Acids Res (2012) 1.11
Branching of the p-nitrophenol (PNP) degradation pathway in burkholderia sp. Strain SJ98: Evidences from genetic characterization of PNP gene cluster. AMB Express (2012) 1.10
CCDB: a curated database of genes involved in cervix cancer. Nucleic Acids Res (2010) 1.09
Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation. PLoS One (2010) 1.08
TumorHoPe: a database of tumor homing peptides. PLoS One (2012) 1.07
ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins. BMC Bioinformatics (2008) 1.07
Identification of NAD interacting residues in proteins. BMC Bioinformatics (2010) 1.07
Prediction methods for B-cell epitopes. Methods Mol Biol (2007) 1.05
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Mol Cancer Ther (2010) 1.05
Prevalence of Candida co-infection in patients with pulmonary tuberculosis. Australas Med J (2013) 1.03
Identification of novel genes involved in light-dependent CRY degradation through a genome-wide RNAi screen. Genes Dev (2008) 1.03
In silico approach for predicting toxicity of peptides and proteins. PLoS One (2013) 1.02
Controlled coupling of a single nitrogen-vacancy center to a silver nanowire. Phys Rev Lett (2011) 1.02
Prediction of polyadenylation signals in human DNA sequences using nucleotide frequencies. In Silico Biol (2009) 1.00
Remodeling and thrombosis following closure of coronary artery fistula with review of management: large distal coronary artery fistula--to close or not to close? Catheter Cardiovasc Interv (2013) 1.00
Prediction of guide strand of microRNAs from its sequence and secondary structure. BMC Bioinformatics (2009) 0.99
Prediction of GTP interacting residues, dipeptides and tripeptides in a protein from its evolutionary information. BMC Bioinformatics (2010) 0.99
Ocular preservatives: associated risks and newer options. Cutan Ocul Toxicol (2009) 0.99
Application of machine learning techniques in predicting MHC binders. Methods Mol Biol (2007) 0.99
BTXpred: prediction of bacterial toxins. In Silico Biol (2007) 0.98
Antiobiotic resistance pattern of biofilm-forming uropathogens isolated from catheterised patients in Pondicherry, India. Australas Med J (2012) 0.97
Prediction and classification of ncRNAs using structural information. BMC Genomics (2014) 0.97
Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides. Nucleic Acids Res (2013) 0.96
RSLpred: an integrative system for predicting subcellular localization of rice proteins combining compositional and evolutionary information. Proteomics (2009) 0.96
Prediction of FAD interacting residues in a protein from its primary sequence using evolutionary information. BMC Bioinformatics (2010) 0.96
Machine learning techniques in disease forecasting: a case study on rice blast prediction. BMC Bioinformatics (2006) 0.95
Changing Trends in Resistance Pattern of Methicillin Resistant Staphylococcus aureus. J Clin Diagn Res (2013) 0.93
A machine learning based method for the prediction of secretory proteins using amino acid composition, their order and similarity-search. In Silico Biol (2008) 0.93
GlycoPP: a webserver for prediction of N- and O-glycosites in prokaryotic protein sequences. PLoS One (2012) 0.93
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials. BMC Bioinformatics (2010) 0.93
Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa. Int J Biol Macromol (2011) 0.93
Computational approach for designing tumor homing peptides. Sci Rep (2013) 0.92
Identification of mannose interacting residues using local composition. PLoS One (2011) 0.92
Shaping a helper T cell identity. Nat Immunol (2007) 0.92