Published in Nucleic Acids Res on November 29, 2012
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In-Vitro and in-Silico characterization of Sophora interrupta plant extract as an anticancer activity. Bioinformation (2014) 0.79
Phytochemica: a platform to explore phytochemicals of medicinal plants. Database (Oxford) (2015) 0.79
Elucidation of molecular targets of bioactive principles of black cumin relevant to its anti-tumour functionality - An Insilico target fishing approach. Bioinformation (2014) 0.78
BioPhytMol: a drug discovery community resource on anti-mycobacterial phytomolecules and plant extracts. J Cheminform (2014) 0.78
Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells. Oxid Med Cell Longev (2015) 0.78
Traditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma. PLoS One (2016) 0.77
How "drug-like" are naturally occurring anti-cancer compounds? J Mol Model (2014) 0.76
TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine. BMC Complement Altern Med (2015) 0.76
Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action. Int J Mol Sci (2017) 0.75
Compounds From Celastraceae Targeting Cancer Pathways and Their Potential Application in Head and Neck Squamous Cell Carcinoma: A Review. Curr Genomics (2017) 0.75
NPCARE: database of natural products and fractional extracts for cancer regulation. J Cheminform (2017) 0.75
TaxKB: a knowledge base for new taxane-related drug discovery. BioData Min (2015) 0.75
A web server for analysis, comparison and prediction of protein ligand binding sites. Biol Direct (2016) 0.75
Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants. Drug Des Devel Ther (2016) 0.75
SerpentinaDB: a database of plant-derived molecules of Rauvolfia serpentina. BMC Complement Altern Med (2015) 0.75
Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development. Front Pharmacol (2016) 0.75
Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod (2012) 13.27
The evolving role of natural products in drug discovery. Nat Rev Drug Discov (2005) 7.18
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Natural products: an evolving role in future drug discovery. Eur J Med Chem (2011) 2.07
HIT: linking herbal active ingredients to targets. Nucleic Acids Res (2010) 1.50
CancerResource: a comprehensive database of cancer-relevant proteins and compound interactions supported by experimental knowledge. Nucleic Acids Res (2010) 1.44
Natural product-likeness score and its application for prioritization of compound libraries. J Chem Inf Model (2007) 1.44
'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries. Drug Discov Today (2008) 1.32
Understanding and classifying metabolite space and metabolite-likeness. PLoS One (2011) 1.29
SuperNatural: a searchable database of available natural compounds. Nucleic Acids Res (2006) 1.18
Analogue-based approaches in anti-cancer compound modelling: the relevance of QSAR models. Org Med Chem Lett (2011) 0.82
Cytotoxic anticancer candidates from terrestrial plants. Anticancer Agents Med Chem (2009) 0.82
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 23.97
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science (2002) 5.47
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell (2006) 5.39
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity (2006) 3.41
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat Immunol (2003) 3.24
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med (2002) 3.16
IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J Immunol (2005) 3.15
Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity (2002) 2.99
Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity (2008) 2.72
Assembling a gene regulatory network for specification of the B cell fate. Dev Cell (2004) 2.46
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol (2008) 2.40
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (2012) 2.30
Bcipep: a database of B-cell epitopes. BMC Genomics (2005) 2.27
Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature (2012) 2.25
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell (2012) 2.20
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol (2008) 2.19
IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev (2003) 2.12
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity (2002) 2.10
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol (2011) 1.95
Support vector machine-based method for subcellular localization of human proteins using amino acid compositions, their order, and similarity search. J Biol Chem (2005) 1.85
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol (2004) 1.82
Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol (2008) 1.78
Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5. Nat Immunol (2005) 1.76
A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol (2006) 1.67
Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol Cell (2002) 1.64
Identification of DNA-binding proteins using support vector machines and evolutionary profiles. BMC Bioinformatics (2007) 1.59
A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity (2009) 1.55
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity (2013) 1.52
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nat Immunol (2009) 1.48
Prediction of mitochondrial proteins using support vector machine and hidden Markov model. J Biol Chem (2005) 1.42
MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes. BMC Res Notes (2009) 1.41
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells. Nat Immunol (2011) 1.41
Classification of nuclear receptors based on amino acid composition and dipeptide composition. J Biol Chem (2004) 1.36
Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol (2012) 1.35
Improved method for linear B-cell epitope prediction using antigen's primary sequence. PLoS One (2013) 1.34
In silico platform for prediction of N-, O- and C-glycosites in eukaryotic protein sequences. PLoS One (2013) 1.29
Genetic networks that regulate B lymphopoiesis. Curr Opin Hematol (2005) 1.26
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol (2013) 1.24
CPPsite: a curated database of cell penetrating peptides. Database (Oxford) (2012) 1.21
IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood (2012) 1.19
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol (2012) 1.18
In silico approaches for designing highly effective cell penetrating peptides. J Transl Med (2013) 1.17
An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol Syst Biol (2011) 1.17
AntiBP2: improved version of antibacterial peptide prediction. BMC Bioinformatics (2010) 1.15
Identification of ATP binding residues of a protein from its primary sequence. BMC Bioinformatics (2009) 1.15
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol (2008) 1.14
POU/TBP cooperativity: a mechanism for enhancer action from a distance. Mol Cell (2002) 1.14
SVM based prediction of RNA-binding proteins using binding residues and evolutionary information. J Mol Recognit (2011) 1.13
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med (2010) 1.12
Branching of the p-nitrophenol (PNP) degradation pathway in burkholderia sp. Strain SJ98: Evidences from genetic characterization of PNP gene cluster. AMB Express (2012) 1.10
CCDB: a curated database of genes involved in cervix cancer. Nucleic Acids Res (2010) 1.09
Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation. PLoS One (2010) 1.08
TumorHoPe: a database of tumor homing peptides. PLoS One (2012) 1.07
ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins. BMC Bioinformatics (2008) 1.07
Identification of NAD interacting residues in proteins. BMC Bioinformatics (2010) 1.07
Prediction methods for B-cell epitopes. Methods Mol Biol (2007) 1.05
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Mol Cancer Ther (2010) 1.05
In silico approach for predicting toxicity of peptides and proteins. PLoS One (2013) 1.02
Prediction of polyadenylation signals in human DNA sequences using nucleotide frequencies. In Silico Biol (2009) 1.00
Remodeling and thrombosis following closure of coronary artery fistula with review of management: large distal coronary artery fistula--to close or not to close? Catheter Cardiovasc Interv (2013) 1.00
Ocular preservatives: associated risks and newer options. Cutan Ocul Toxicol (2009) 0.99
Prediction of GTP interacting residues, dipeptides and tripeptides in a protein from its evolutionary information. BMC Bioinformatics (2010) 0.99
Prediction of guide strand of microRNAs from its sequence and secondary structure. BMC Bioinformatics (2009) 0.99
Application of machine learning techniques in predicting MHC binders. Methods Mol Biol (2007) 0.99
BTXpred: prediction of bacterial toxins. In Silico Biol (2007) 0.98
Prediction and classification of ncRNAs using structural information. BMC Genomics (2014) 0.97
RSLpred: an integrative system for predicting subcellular localization of rice proteins combining compositional and evolutionary information. Proteomics (2009) 0.96
Prediction of FAD interacting residues in a protein from its primary sequence using evolutionary information. BMC Bioinformatics (2010) 0.96
Hemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides. Nucleic Acids Res (2013) 0.96
CancerDR: cancer drug resistance database. Sci Rep (2013) 0.96
Machine learning techniques in disease forecasting: a case study on rice blast prediction. BMC Bioinformatics (2006) 0.95
GlycoPP: a webserver for prediction of N- and O-glycosites in prokaryotic protein sequences. PLoS One (2012) 0.93
A machine learning based method for the prediction of secretory proteins using amino acid composition, their order and similarity-search. In Silico Biol (2008) 0.93
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials. BMC Bioinformatics (2010) 0.93
Shaping a helper T cell identity. Nat Immunol (2007) 0.92
Identification of mannose interacting residues using local composition. PLoS One (2011) 0.92
Computational approach for designing tumor homing peptides. Sci Rep (2013) 0.92
HIVsirDB: a database of HIV inhibiting siRNAs. PLoS One (2011) 0.91
Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis. Blood (2010) 0.91
ccPDB: compilation and creation of data sets from Protein Data Bank. Nucleic Acids Res (2011) 0.90
PRRDB: a comprehensive database of pattern-recognition receptors and their ligands. BMC Genomics (2008) 0.90
Prediction of neurotoxins based on their function and source. In Silico Biol (2007) 0.90
Designing of highly effective complementary and mismatch siRNAs for silencing a gene. PLoS One (2011) 0.90
Prediction of nuclear proteins using SVM and HMM models. BMC Bioinformatics (2009) 0.90
CyclinPred: a SVM-based method for predicting cyclin protein sequences. PLoS One (2008) 0.89
Synthesis and antiamoebic activity of metronidazole thiosemicarbazone analogues. Eur J Med Chem (2007) 0.88
PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors. BMC Bioinformatics (2013) 0.88
A simple approach for predicting protein-protein interactions. Curr Protein Pept Sci (2010) 0.88
Hmrbase: a database of hormones and their receptors. BMC Genomics (2009) 0.88
COPid: composition based protein identification. In Silico Biol (2008) 0.87
OxDBase: a database of oxygenases involved in biodegradation. BMC Res Notes (2009) 0.87
Designing of interferon-gamma inducing MHC class-II binders. Biol Direct (2013) 0.86
Crystallization and characterization of PU.1/IRF-4/DNA ternary complex. J Struct Biol (2002) 0.86
Prediction and classification of aminoacyl tRNA synthetases using PROSITE domains. BMC Genomics (2010) 0.86
ProGlycProt: a repository of experimentally characterized prokaryotic glycoproteins. Nucleic Acids Res (2011) 0.85
A web server for predicting inhibitors against bacterial target GlmU protein. BMC Pharmacol (2011) 0.85
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis. BMC Bioinformatics (2010) 0.85