Published in Nature on March 17, 2010
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
The genomic signature of dog domestication reveals adaptation to a starch-rich diet. Nature (2013) 3.61
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46
Transmissible [corrected] dog cancer genome reveals the origin and history of an ancient cell lineage. Science (2014) 2.58
SLAF-seq: an efficient method of large-scale de novo SNP discovery and genotyping using high-throughput sequencing. PLoS One (2013) 2.36
A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids. Genome Res (2011) 2.28
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet (2011) 2.24
The genomics of selection in dogs and the parallel evolution between dogs and humans. Nat Commun (2013) 1.86
Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proc Natl Acad Sci U S A (2012) 1.78
Genome sequencing highlights the dynamic early history of dogs. PLoS Genet (2014) 1.77
Three roads diverged? Routes to phylogeographic inference. Trends Ecol Evol (2010) 1.74
Worldwide patterns of ancestry, divergence, and admixture in domesticated cattle. PLoS Genet (2014) 1.72
Regions of homozygosity in the porcine genome: consequence of demography and the recombination landscape. PLoS Genet (2012) 1.63
Man's best friend becomes biology's best in show: genome analyses in the domestic dog. Annu Rev Genet (2010) 1.51
Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegans. PLoS One (2010) 1.44
Whole-genome sequencing of six dog breeds from continuous altitudes reveals adaptation to high-altitude hypoxia. Genome Res (2014) 1.42
Understanding the origin of species with genome-scale data: modelling gene flow. Nat Rev Genet (2013) 1.41
A unique human-fox burial from a pre-Natufian cemetery in the Levant (Jordan). PLoS One (2011) 1.40
A 33,000-year-old incipient dog from the Altai Mountains of Siberia: evidence of the earliest domestication disrupted by the Last Glacial Maximum. PLoS One (2011) 1.29
The "domestication syndrome" in mammals: a unified explanation based on neural crest cell behavior and genetics. Genetics (2014) 1.28
New World cattle show ancestry from multiple independent domestication events. Proc Natl Acad Sci U S A (2013) 1.27
Genomic analysis reveals selection for Asian genes in European pigs following human-mediated introgression. Nat Commun (2014) 1.27
Genetic structure in village dogs reveals a Central Asian domestication origin. Proc Natl Acad Sci U S A (2015) 1.21
A high-resolution integrated map of copy number polymorphisms within and between breeds of the modern domesticated dog. BMC Genomics (2011) 1.18
Origins of domestic dog in southern East Asia is supported by analysis of Y-chromosome DNA. Heredity (Edinb) (2011) 1.18
Whole mitochondrial genome sequencing of domestic horses reveals incorporation of extensive wild horse diversity during domestication. BMC Evol Biol (2011) 1.17
Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome (2011) 1.16
Out of southern East Asia: the natural history of domestic dogs across the world. Cell Res (2015) 1.15
Ancient DNA analysis affirms the canid from Altai as a primitive dog. PLoS One (2013) 1.12
Evolutionary genomics of dog domestication. Mamm Genome (2012) 1.11
Tempo and mode of genome evolution in a 50,000-generation experiment. Nature (2016) 1.10
DoGSD: the dog and wolf genome SNP database. Nucleic Acids Res (2014) 1.09
Novel origins of copy number variation in the dog genome. Genome Biol (2012) 1.06
Breed-predispositions to cancer in pedigree dogs. ISRN Vet Sci (2013) 1.06
Assessment of canine BEST1 variations identifies new mutations and establishes an independent bestrophinopathy model (cmr3). Mol Vis (2010) 1.05
Franklin H. Epstein Lecture. Both ends of the leash--the human links to good dogs with bad genes. N Engl J Med (2012) 1.05
A comparison of brain gene expression levels in domesticated and wild animals. PLoS Genet (2012) 1.04
Copy number variation in the domestic dog. Mamm Genome (2011) 1.01
The domestic dog: man's best friend in the genomic era. Genome Biol (2011) 1.00
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Mol Vis (2010) 0.99
Comprehensive study of mtDNA among Southwest Asian dogs contradicts independent domestication of wolf, but implies dog-wolf hybridization. Ecol Evol (2011) 0.99
Derived variants at six genes explain nearly half of size reduction in dog breeds. Genome Res (2013) 0.98
The insulin-like growth factor 1 receptor (IGF1R) contributes to reduced size in dogs. Mamm Genome (2012) 0.98
Myxomatous mitral valve disease in dogs: does size matter? J Vet Cardiol (2012) 0.97
Phylogenetic distinctiveness of Middle Eastern and Southeast Asian village dog Y chromosomes illuminates dog origins. PLoS One (2011) 0.97
Mapping Loci for fox domestication: deconstruction/reconstruction of a behavioral phenotype. Behav Genet (2010) 0.96
Combining markers into haplotypes can improve population structure inference. Genetics (2011) 0.96
Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs. Proc Natl Acad Sci U S A (2015) 0.94
Domestic dogs and cancer research: a breed-based genomics approach. ILAR J (2014) 0.93
Geometric analysis of macronutrient selection in breeds of the domestic dog, Canis lupus familiaris. Behav Ecol (2012) 0.93
The taming of the neural crest: a developmental perspective on the origins of morphological covariation in domesticated mammals. R Soc Open Sci (2016) 0.93
Assessment of coyote-wolf-dog admixture using ancestry-informative diagnostic SNPs. Mol Ecol (2013) 0.92
Insights into morphology and disease from the dog genome project. Annu Rev Cell Dev Biol (2014) 0.91
Estimating the population mutation rate from a de novo assembled Bactrian camel genome and cross-species comparison with dromedary ESTs. J Hered (2013) 0.91
Pre-Columbian origins of Native American dog breeds, with only limited replacement by European dogs, confirmed by mtDNA analysis. Proc Biol Sci (2013) 0.91
Comparative oncology: what dogs and other species can teach us about humans with cancer. Philos Trans R Soc Lond B Biol Sci (2015) 0.91
Comparative Genomics of X-linked Muscular Dystrophies: The Golden Retriever Model. Curr Genomics (2013) 0.90
Molecular ecology and selection in the drought-related Asr gene polymorphisms in wild and cultivated common bean (Phaseolus vulgaris L.). BMC Genet (2012) 0.90
Genomic analyses of modern dog breeds. Mamm Genome (2012) 0.89
Multilocus detection of wolf x dog hybridization in italy, and guidelines for marker selection. PLoS One (2014) 0.89
Efficient recovery of whole blood RNA--a comparison of commercial RNA extraction protocols for high-throughput applications in wildlife species. BMC Biotechnol (2012) 0.89
Embryonic development of goldfish (Carassius auratus): a model for the study of evolutionary change in developmental mechanisms by artificial selection. Dev Dyn (2013) 0.89
Decreased Nucleotide and Expression Diversity and Modified Coexpression Patterns Characterize Domestication in the Common Bean. Plant Cell (2014) 0.89
Detecting directional selection in the presence of recent admixture in African-Americans. Genetics (2010) 0.88
A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit. PLoS Genet (2013) 0.88
Genetics of behavior in the silver fox. Mamm Genome (2011) 0.88
Breed-specific hematological phenotypes in the dog: a natural resource for the genetic dissection of hematological parameters in a mammalian species. PLoS One (2013) 0.88
Allometry of sexual size dimorphism in domestic dog. PLoS One (2012) 0.87
NetView: a high-definition network-visualization approach to detect fine-scale population structures from genome-wide patterns of variation. PLoS One (2012) 0.87
Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes). BMC Genomics (2011) 0.87
Genome-wide signatures of population bottlenecks and diversifying selection in European wolves. Heredity (Edinb) (2013) 0.86
Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia. BMC Genet (2013) 0.85
Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex. Mamm Genome (2013) 0.85
Dog sperm head morphometry: its diversity and evolution. Asian J Androl (2016) 0.84
Genome-wide analysis in chicken reveals that local levels of genetic diversity are mainly governed by the rate of recombination. BMC Genomics (2013) 0.84
Brief communication: DNA from early Holocene American dog. Am J Phys Anthropol (2011) 0.84
Identification of recent hybridization between gray wolves and domesticated dogs by SNP genotyping. Mamm Genome (2012) 0.84
Multi-locus analysis reveals a different pattern of genetic diversity for mitochondrial and nuclear DNA between wild and domestic pigs in East Asia. PLoS One (2011) 0.83
Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24. PLoS Genet (2014) 0.83
A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs. Mol Vis (2013) 0.83
A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs. Cell Metab (2016) 0.83
Conflict between genetic and phenotypic differentiation: the evolutionary history of a 'lost and rediscovered' shorebird. PLoS One (2011) 0.83
Diet adaptation in dog reflects spread of prehistoric agriculture. Heredity (Edinb) (2016) 0.82
Hybrid origin of European commercial pigs examined by an in-depth haplotype analysis on chromosome 1. Front Genet (2015) 0.82
Genome analysis of the domestic dog (Korean Jindo) by massively parallel sequencing. DNA Res (2012) 0.82
Frequent alteration of the tumor suppressor gene APC in sporadic canine colorectal tumors. PLoS One (2012) 0.81
Dominance in Domestic Dogs: A Quantitative Analysis of Its Behavioural Measures. PLoS One (2015) 0.81
How do SNP ascertainment schemes and population demographics affect inferences about population history? BMC Genomics (2015) 0.81
Graph hierarchies for phylogeography. Philos Trans R Soc Lond B Biol Sci (2013) 0.81
Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias. Mol Ecol (2011) 0.81
Strong selection for behavioural resilience in Australian stock working dogs identified by selective sweep analysis. Canine Genet Epidemiol (2015) 0.80
Evidence of coat color variation sheds new light on ancient canids. PLoS One (2013) 0.80
So many doggone traits: mapping genetics of multiple phenotypes in the domestic dog. Hum Mol Genet (2012) 0.80
Analysis of structural diversity in wolf-like canids reveals post-domestication variants. BMC Genomics (2014) 0.79
Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN. PLoS One (2015) 0.79
Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds. BMC Genomics (2015) 0.79
Dog Breed Differences in Visual Communication with Humans. PLoS One (2016) 0.79
Breed-specific ancestry studies and genome-wide association analysis highlight an association between the MYH9 gene and heat tolerance in Alaskan sprint racing sled dogs. Mamm Genome (2011) 0.79
Comparison of owner-reported behavioral characteristics among genetically clustered breeds of dog (Canis familiaris). Sci Rep (2015) 0.79
Comparative Analysis of Genome Diversity in Bullmastiff Dogs. PLoS One (2016) 0.78
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Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40
Population genomics of domestic and wild yeasts. Nature (2009) 11.79
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet (2006) 8.46
The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
Genetic evidence for an East Asian origin of domestic dogs. Science (2002) 7.25
Genetic structure of the purebred domestic dog. Science (2004) 6.39
A single IGF1 allele is a major determinant of small size in dogs. Science (2007) 4.68
Ancient DNA evidence for Old World origin of New World dogs. Science (2002) 4.43
Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87
A -defensin mutation causes black coat color in domestic dogs. Science (2007) 3.47
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science (2009) 3.29
mtDNA data indicate a single origin for dogs south of Yangtze River, less than 16,300 years ago, from numerous wolves. Mol Biol Evol (2009) 3.23
Pattern of polymorphism after strong artificial selection in a domestication event. Proc Natl Acad Sci U S A (2004) 3.09
Coat variation in the domestic dog is governed by variants in three genes. Science (2009) 2.70
Complex population structure in African village dogs and its implications for inferring dog domestication history. Proc Natl Acad Sci U S A (2009) 2.42
Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds. Genome Res (2007) 2.26
Evidence of three maternal lineages in Near Eastern sheep supporting multiple domestication events. Proc Biol Sci (2005) 2.14
Genes of domestic mammals augmented by backcrossing with wild ancestors. Trends Genet (2005) 2.04
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The legacy of domestication: accumulation of deleterious mutations in the dog genome. Mol Biol Evol (2008) 1.47
Mitochondrial DNA from prehistoric canids highlights relationships between dogs and South-East European wolves. Mol Biol Evol (2005) 1.42
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A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
The variant call format and VCFtools. Bioinformatics (2011) 25.88
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature (2005) 23.04
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell (2006) 16.05
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Genes mirror geography within Europe. Nature (2008) 14.23
A global reference for human genetic variation. Nature (2015) 12.85
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet (2009) 9.16
Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study. Lancet (2008) 9.10
Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet (2008) 8.92
A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet (2008) 8.64
Signals of recent positive selection in a worldwide sample of human populations. Genome Res (2009) 8.38
Genomewide association study of leprosy. N Engl J Med (2009) 8.17
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
Mapping human genetic diversity in Asia. Science (2009) 7.40
Demographic history and rare allele sharing among human populations. Proc Natl Acad Sci U S A (2011) 7.36
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Proportionally more deleterious genetic variation in European than in African populations. Nature (2008) 6.61
KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science (2003) 6.60
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
Genetic structure of the purebred domestic dog. Science (2004) 6.39
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet (2009) 6.04
Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res (2002) 5.99
Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proc Natl Acad Sci U S A (2005) 5.94
A QTL for rice grain width and weight encodes a previously unknown RING-type E3 ubiquitin ligase. Nat Genet (2007) 5.70
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet (2003) 5.51
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science (2005) 5.47
Genome-wide association mapping reveals a rich genetic architecture of complex traits in Oryza sativa. Nat Commun (2011) 5.41
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Localizing recent adaptive evolution in the human genome. PLoS Genet (2007) 5.11
Recurrent R-spondin fusions in colon cancer. Nature (2012) 5.10
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Patterns of positive selection in six Mammalian genomes. PLoS Genet (2008) 4.69
Gene expression analysis using oligonucleotide arrays produced by maskless photolithography. Genome Res (2002) 4.69
A single IGF1 allele is a major determinant of small size in dogs. Science (2007) 4.68
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice. Proc Natl Acad Sci U S A (2009) 4.65
ClinGen--the Clinical Genome Resource. N Engl J Med (2015) 4.45
Ancient DNA evidence for Old World origin of New World dogs. Science (2002) 4.43
The functional spectrum of low-frequency coding variation. Genome Biol (2011) 4.42
A Markov chain Monte Carlo approach for joint inference of population structure and inbreeding rates from multilocus genotype data. Genetics (2007) 4.31
A rice quantitative trait locus for salt tolerance encodes a sodium transporter. Nat Genet (2005) 4.28
Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism. Antimicrob Agents Chemother (2006) 4.14
Classic selective sweeps were rare in recent human evolution. Science (2011) 4.09
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Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87
Genome-wide patterns of nucleotide polymorphism in domesticated rice. PLoS Genet (2007) 3.83
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet (2008) 3.61
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet (2007) 3.61
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet (2009) 3.59
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults. JAMA (2012) 3.52
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46