Published in Nature on February 21, 2008
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Genes mirror geography within Europe. Nature (2008) 14.23
Human genetic variation and its contribution to complex traits. Nat Rev Genet (2009) 12.11
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Reconstructing Indian population history. Nature (2009) 9.28
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet (2009) 9.16
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Genome structural variation discovery and genotyping. Nat Rev Genet (2011) 7.34
Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28
Mobile elements create structural variation: analysis of a complete human genome. Genome Res (2009) 7.06
Population analysis of large copy number variants and hotspots of human genetic disease. Am J Hum Genet (2009) 6.79
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. Annu Rev Genomics Hum Genet (2008) 6.06
Constructing genomic maps of positive selection in humans: where do we go from here? Genome Res (2009) 5.88
Building the sequence map of the human pan-genome. Nat Biotechnol (2009) 5.53
Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A (2009) 5.39
Inference of population structure using dense haplotype data. PLoS Genet (2012) 4.87
Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet (2012) 4.85
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature (2010) 4.64
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing. Hum Mol Genet (2010) 3.50
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Evolutionary toggling of the MAPT 17q21.31 inversion region. Nat Genet (2008) 3.42
The role of geography in human adaptation. PLoS Genet (2009) 3.41
The genome-wide structure of the Jewish people. Nature (2010) 3.37
Applications of next generation sequencing in molecular ecology of non-model organisms. Heredity (Edinb) (2010) 3.22
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe. PLoS One (2008) 3.09
Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer. BMC Biol (2009) 2.94
Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet (2009) 2.93
The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet (2008) 2.79
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76
Hybridization, ecological races and the nature of species: empirical evidence for the ease of speciation. Philos Trans R Soc Lond B Biol Sci (2008) 2.75
Inferring human colonization history using a copying model. PLoS Genet (2008) 2.64
Ascertainment biases in SNP chips affect measures of population divergence. Mol Biol Evol (2010) 2.56
Using environmental correlations to identify loci underlying local adaptation. Genetics (2010) 2.52
Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet (2008) 2.49
Recent advances in the genetics of autoimmune disease. Annu Rev Immunol (2009) 2.41
High-resolution haplotype block structure in the cattle genome. BMC Genet (2009) 2.35
Genetic structure of the Han Chinese population revealed by genome-wide SNP variation. Am J Hum Genet (2009) 2.33
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico. Proc Natl Acad Sci U S A (2009) 2.32
Genomic patterns of homozygosity in worldwide human populations. Am J Hum Genet (2012) 2.30
Population genetic inference from genomic sequence variation. Genome Res (2010) 2.29
A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids. Genome Res (2011) 2.28
Methodological challenges of genome-wide association analysis in Africa. Nat Rev Genet (2010) 2.27
Spatial patterns of variation due to natural selection in humans. Nat Rev Genet (2009) 2.18
Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell (2013) 2.17
Inference of unexpected genetic relatedness among individuals in HapMap Phase III. Am J Hum Genet (2010) 2.16
Adaptations to climate-mediated selective pressures in humans. PLoS Genet (2011) 2.15
A model-based approach for analysis of spatial structure in genetic data. Nat Genet (2012) 2.02
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. PLoS Genet (2009) 2.02
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc Natl Acad Sci U S A (2010) 1.97
Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans. Genome Res (2010) 1.94
Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: a susceptibility region for neurological dysfunction including developmental and language delay. Hum Genet (2011) 1.94
The relationship between imputation error and statistical power in genetic association studies in diverse populations. Am J Hum Genet (2009) 1.89
A novel DNA sequence database for analyzing human demographic history. Genome Res (2008) 1.85
The genetics of major depression. Neuron (2014) 1.80
Resolving the evolution of extant and extinct ruminants with high-throughput phylogenomics. Proc Natl Acad Sci U S A (2009) 1.79
Genome-wide data substantiate Holocene gene flow from India to Australia. Proc Natl Acad Sci U S A (2013) 1.78
Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays. Nucleic Acids Res (2010) 1.77
Out of Africa: modern human origins special feature: explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa. Proc Natl Acad Sci U S A (2009) 1.76
Learning about human population history from ancient and modern genomes. Nat Rev Genet (2011) 1.74
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet (2012) 1.74
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. Proc Natl Acad Sci U S A (2009) 1.73
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome Res (2009) 1.73
Archaic human ancestry in East Asia. Proc Natl Acad Sci U S A (2011) 1.72
Extensive copy-number variation of the human olfactory receptor gene family. Am J Hum Genet (2008) 1.71
Genome-wide association studies: implications for multiethnic samples. Hum Mol Genet (2008) 1.69
The evolution of human genetic and phenotypic variation in Africa. Curr Biol (2010) 1.65
Human population dispersal "Out of Africa" estimated from linkage disequilibrium and allele frequencies of SNPs. Genome Res (2011) 1.64
Genome-wide insights into the patterns and determinants of fine-scale population structure in humans. Am J Hum Genet (2009) 1.64
A worldwide survey of human male demographic history based on Y-SNP and Y-STR data from the HGDP-CEPH populations. Mol Biol Evol (2009) 1.56
Race and ancestry in biomedical research: exploring the challenges. Genome Med (2009) 1.55
A comparison of worldwide phonemic and genetic variation in human populations. Proc Natl Acad Sci U S A (2015) 1.54
Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia. Am J Hum Genet (2016) 1.53
Genetic variation and recent positive selection in worldwide human populations: evidence from nearly 1 million SNPs. PLoS One (2009) 1.53
Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems. BMC Bioinformatics (2011) 1.50
High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians. Genome Biol (2009) 1.49
Possible positive selection for an arsenic-protective haplotype in humans. Environ Health Perspect (2012) 1.49
The general population cohort in rural south-western Uganda: a platform for communicable and non-communicable disease studies. Int J Epidemiol (2013) 1.48
Fine-scaled human genetic structure revealed by SNP microarrays. Genome Res (2009) 1.48
Comparing spatial maps of human population-genetic variation using Procrustes analysis. Stat Appl Genet Mol Biol (2010) 1.48
Global diversity, population stratification, and selection of human copy-number variation. Science (2015) 1.48
Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping. Genomics (2010) 1.47
Population structure, migration, and diversifying selection in the Netherlands. Eur J Hum Genet (2013) 1.47
Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axis. Proc Natl Acad Sci U S A (2010) 1.47
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. Ophthalmology (2010) 1.44
Accuracy of CNV Detection from GWAS Data. PLoS One (2011) 1.44
A genomic portrait of haplotype diversity and signatures of selection in indigenous southern African populations. PLoS Genet (2015) 1.43
Copy number variation influences gene expression and metabolic traits in mice. Hum Mol Genet (2009) 1.42
Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data. Genetics (2009) 1.42
A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans. Genome Biol (2009) 1.41
Adaptations to new environments in humans: the role of subtle allele frequency shifts. Philos Trans R Soc Lond B Biol Sci (2010) 1.40
Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population. J Hum Genet (2009) 1.40
Population structure and genome-wide patterns of variation in Ireland and Britain. Eur J Hum Genet (2010) 1.39
Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder. Am J Hum Genet (2013) 1.39
Genetic structure of human populations. Science (2002) 30.91
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol (2010) 26.41
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science (2008) 20.68
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res (2007) 19.07
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron (2011) 18.73
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. Bioinformatics (2007) 16.52
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Rare variants create synthetic genome-wide associations. PLoS Biol (2010) 14.43
A human genome diversity cell line panel. Science (2002) 14.11
Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet (2005) 14.09
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron (2004) 13.99
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet (2007) 12.27
A survey of genetic human cortical gene expression. Nat Genet (2007) 12.04
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc Natl Acad Sci U S A (2005) 10.22
The pattern of polymorphism in Arabidopsis thaliana. PLoS Biol (2005) 10.13
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature (2009) 9.47
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet (2011) 9.10
Automating sequence-based detection and genotyping of SNPs from diploid samples. Nat Genet (2006) 9.04
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet (2006) 8.46
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol (2013) 7.97
Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron (2010) 7.87
The knockout mouse project. Nat Genet (2004) 7.80
Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol (2006) 7.32
Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28
The microRNA spectrum in 12 body fluids. Clin Chem (2010) 6.82
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals. Hum Mol Genet (2006) 5.50
A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet (2003) 5.34
Promoter features related to tissue specificity as measured by Shannon entropy. Genome Biol (2005) 5.19
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol (2012) 5.18
Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA (2012) 5.16
Features of evolution and expansion of modern humans, inferred from genomewide microsatellite markers. Am J Hum Genet (2003) 5.14
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet (2011) 4.93
Gene tree discordance, phylogenetic inference and the multispecies coalescent. Trends Ecol Evol (2009) 4.91
Genetic variation and population structure in native Americans. PLoS Genet (2007) 4.87
A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet (2008) 4.75
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry (2011) 4.29
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Adjustment of genomic waves in signal intensities from whole-genome SNP genotyping platforms. Nucleic Acids Res (2008) 4.22
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. Lancet Neurol (2010) 4.19