Published in Methods Mol Biol on January 01, 2010
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
Initial sequence of the chimpanzee genome and comparison with the human genome. Nature (2005) 25.67
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Alu repeats and human genomic diversity. Nat Rev Genet (2002) 12.40
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition. Cell (1993) 8.99
High frequency retrotransposition in cultured mammalian cells. Cell (1996) 8.60
Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition. Cell (1996) 8.21
LINE-mediated retrotransposition of marked Alu sequences. Nat Genet (2003) 7.32
Alu repeats and human disease. Mol Genet Metab (1999) 6.64
Hot L1s account for the bulk of retrotransposition in the human population. Proc Natl Acad Sci U S A (2003) 6.16
Exon shuffling by L1 retrotransposition. Science (1999) 4.99
OligoCalc: an online oligonucleotide properties calculator. Nucleic Acids Res (2007) 4.96
Genomic deletions created upon LINE-1 retrotransposition. Cell (2002) 4.92
Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons. Proc Natl Acad Sci U S A (1997) 4.80
Human l1 retrotransposition is associated with genetic instability in vivo. Cell (2002) 4.79
Human population genetic structure and inference of group membership. Am J Hum Genet (2003) 4.73
Alu sequences are processed 7SL RNA genes. Nature (1984) 4.67
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Nat Genet (2002) 4.58
Isolation of an active human transposable element. Science (1991) 3.99
The impact of L1 retrotransposons on the human genome. Nat Genet (1998) 3.56
A de novo Alu insertion results in neurofibromatosis type 1. Nature (1991) 3.29
Human genomic deletions mediated by recombination between Alu elements. Am J Hum Genet (2006) 3.15
Master genes in mammalian repetitive DNA amplification. Trends Genet (1992) 3.11
The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data. Am J Hum Genet (2000) 2.91
The age of Alu subfamilies. J Mol Evol (1996) 2.85
Multiple fates of L1 retrotransposition intermediates in cultured human cells. Mol Cell Biol (2005) 2.77
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion. Nat Genet (1994) 2.68
Evolution of the master Alu gene(s). J Mol Evol (1991) 2.65
Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure. Biochemistry (1998) 2.59
LINEs and Alus--the polyA connection. Nat Genet (1997) 2.58
Genetic variation of recent Alu insertions in human populations. J Mol Evol (1996) 2.56
SVA elements are nonautonomous retrotransposons that cause disease in humans. Am J Hum Genet (2003) 2.55
SINE insertions: powerful tools for molecular systematics. Bioessays (2000) 2.49
Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms. Genome Res (2003) 2.47
Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates. Genome Res (2005) 2.46
Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity. J Mol Biol (2001) 2.16
Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells. Hum Mol Genet (1999) 2.15
LINEs mobilize SINEs in the eel through a shared 3' sequence. Cell (2002) 2.15
Recently transposed Alu repeats result from multiple source genes. Nucleic Acids Res (1990) 2.10
The evolutionary history of human DNA transposons: evidence for intense activity in the primate lineage. Genome Res (2007) 2.06
Noninvasive genetic tracking of the endangered Pyrenean brown bear population. Mol Ecol (1997) 1.90
Alu elements and hominid phylogenetics. Proc Natl Acad Sci U S A (2003) 1.81
Alu retrotransposition-mediated deletion. J Mol Biol (2005) 1.79
Retrotransposition of Alu elements: how many sources? Trends Genet (2004) 1.73
Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages. Nucleic Acids Res (2005) 1.73
A transient assay reveals that cultured human cells can accommodate multiple LINE-1 retrotransposition events. Anal Biochem (2000) 1.71
SINEs of speciation: tracking lineages with retroposons. Trends Ecol Evol (2004) 1.64
Alu recombination-mediated structural deletions in the chimpanzee genome. PLoS Genet (2007) 1.59
SINEs of a nearly perfect character. Syst Biol (2006) 1.59
Short interspersed elements (SINEs) are a major source of canine genomic diversity. Genome Res (2005) 1.57
Phylogenetic relationships and ancient incomplete lineage sorting among cichlid fishes in Lake Tanganyika as revealed by analysis of the insertion of retroposons. Mol Biol Evol (2001) 1.54
Determination of the phylogenetic relationships among Pacific salmonids by using short interspersed elements (SINEs) as temporal landmarks of evolution. Proc Natl Acad Sci U S A (1993) 1.53
Alu insertion loci and platyrrhine primate phylogeny. Mol Phylogenet Evol (2005) 1.49
Recently integrated Alu elements and human genomic diversity. Mol Biol Evol (2003) 1.46
Retrotransposon-based insertion polymorphisms (RBIP) for high throughput marker analysis. Plant J (1998) 1.46
Functional differences between the human LINE retrotransposon and retroviral reverse transcriptases for in vivo mRNA reverse transcription. EMBO J (1997) 1.42
Alu insertion polymorphisms for the study of human genomic diversity. Genetics (2001) 1.40
Alu RNA transcripts in human embryonal carcinoma cells. Model of post-transcriptional selection of master sequences. J Mol Biol (1992) 1.40
Genome-wide analysis of the human Alu Yb-lineage. Hum Genomics (2004) 1.33
Recently integrated human Alu repeats: finding needles in the haystack. Genetica (1999) 1.32
Under the genomic radar: the stealth model of Alu amplification. Genome Res (2005) 1.31
Recently integrated Alu retrotransposons are essentially neutral residents of the human genome. Gene (2006) 1.31
Development of an Alu-based, real-time PCR method for quantitation of human DNA in forensic samples. J Forensic Sci (2003) 1.30
Different evolutionary fates of recently integrated human and chimpanzee LINE-1 retrotransposons. Gene (2006) 1.26
Human DNA quantitation using Alu element-based polymerase chain reaction. Anal Biochem (2003) 1.24
Multiplex polymerase chain reaction for simultaneous quantitation of human nuclear, mitochondrial, and male Y-chromosome DNA: application in human identification. Anal Biochem (2005) 1.17
Analysis of the human Alu Ya-lineage. J Mol Biol (2004) 1.12
Conservation genetics of the European brown bear--a study using excremental PCR of nuclear and mitochondrial sequences. Mol Ecol (1995) 1.11
Inference of human geographic origins using Alu insertion polymorphisms. Forensic Sci Int (2005) 1.08
Comprehensive analysis of two Alu Yd subfamilies. J Mol Evol (2003) 1.06
Quantification of DNA in forensic samples. Anal Bioanal Chem (2003) 1.03
Analysis of the human Alu Ye lineage. BMC Evol Biol (2005) 1.03
IRE-bubble PCR: a rapid method for efficient and representative amplification of human genomic DNA sequences from complex sources. Genomics (1994) 0.99
Simultaneous determination of total human and male DNA using a duplex real-time PCR assay. J Forensic Sci (2006) 0.96
SINEs of progress: Mobile element applications to molecular ecology. Mol Ecol (2007) 0.96
Phylogenetic affinities of tarsier in the context of primate Alu repeats. Mol Phylogenet Evol (1999) 0.92
First application of the SINE (short interspersed repetitive element) method to infer phylogenetic relationships in reptiles: an example from the turtle superfamily Testudinoidea. Mol Biol Evol (2004) 0.92
The rise and fall of the CR1 subfamily in the lineage leading to penguins. Gene (2005) 0.91
A SINE-based dichotomous key for primate identification. Gene (2006) 0.90
Retroposon mapping in molecular systematics. Methods Mol Biol (2004) 0.89
Mobile element-based assay for human gender determination. Anal Biochem (2003) 0.78
Generation of human DNA profiles by Alu-based multiplex polymerase chain reaction. Anal Biochem (2003) 0.77
An Alu-based, MGB Eclipse real-time PCR method for quantitation of human DNA in forensic samples. J Forensic Sci (2005) 0.77
Species and sex identification of western lowland gorillas (Gorilla gorilla gorilla), eastern lowland gorillas (Gorilla beringei graueri) and humans. Primates (2005) 0.76
Human genomic DNA quantitation system, H-Quant: development and validation for use in forensic casework. J Forensic Sci (2007) 0.76
Multiplex polymerase chain reaction of Alu polymorphic insertions. Electrophoresis (1998) 0.75
A more sensitive method for the quantitation of genomic DNA by Alu amplification. J Forensic Sci (2002) 0.75
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Mapping copy number variation by population-scale genome sequencing. Nature (2011) 12.55
The impact of retrotransposons on human genome evolution. Nat Rev Genet (2009) 8.08
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Mobile elements create structural variation: analysis of a complete human genome. Genome Res (2009) 7.06
The genome of a songbird. Nature (2010) 5.90
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
Human population genetic structure and inference of group membership. Am J Hum Genet (2003) 4.73
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Nat Genet (2002) 4.58
dbRIP: a highly integrated database of retrotransposon insertion polymorphisms in humans. Hum Mutat (2006) 4.23
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
Repetitive elements may comprise over two-thirds of the human genome. PLoS Genet (2011) 3.70
Mobile elements and mammalian genome evolution. Curr Opin Genet Dev (2003) 3.68
Mammalian retroelements. Genome Res (2002) 3.49
Human genomic deletions mediated by recombination between Alu elements. Am J Hum Genet (2006) 3.15
A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet (2011) 3.14
Birth of a chimeric primate gene by capture of the transposase gene from a mobile element. Proc Natl Acad Sci U S A (2006) 2.81
Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms. Genome Res (2003) 2.47
A comprehensive analysis of recently integrated human Ta L1 elements. Am J Hum Genet (2002) 2.47
SVA elements: a hominid-specific retroposon family. J Mol Biol (2005) 2.39
Estimating the retrotransposition rate of human Alu elements. Gene (2006) 1.85
Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies. Annu Rev Gerontol Geriatr (2007) 1.85
Alu elements and hominid phylogenetics. Proc Natl Acad Sci U S A (2003) 1.81
L1 recombination-associated deletions generate human genomic variation. Proc Natl Acad Sci U S A (2008) 1.79
Active Alu element "A-tails": size does matter. Genome Res (2002) 1.79
Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica. Genome Res (2007) 1.79
Alu retrotransposition-mediated deletion. J Mol Biol (2005) 1.79
Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms. Genome Res (2002) 1.78
Differential alu mobilization and polymorphism among the human and chimpanzee lineages. Genome Res (2004) 1.77
Retrotransposition of Alu elements: how many sources? Trends Genet (2004) 1.73
Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages. Nucleic Acids Res (2005) 1.73
Whole genome computational comparative genomics: A fruitful approach for ascertaining Alu insertion polymorphisms. Gene (2006) 1.68
Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations. Genome Res (2013) 1.66
Emergence of primate genes by retrotransposon-mediated sequence transduction. Proc Natl Acad Sci U S A (2006) 1.66
Alu recombination-mediated structural deletions in the chimpanzee genome. PLoS Genet (2007) 1.59
SINEs of a nearly perfect character. Syst Biol (2006) 1.59
Mobile element scanning (ME-Scan) by targeted high-throughput sequencing. BMC Genomics (2010) 1.54
Alu insertion loci and platyrrhine primate phylogeny. Mol Phylogenet Evol (2005) 1.49
Mobile DNA in Old World monkeys: a glimpse through the rhesus macaque genome. Science (2007) 1.47
Recently integrated Alu elements and human genomic diversity. Mol Biol Evol (2003) 1.46
5'-Transducing SVA retrotransposon groups spread efficiently throughout the human genome. Genome Res (2009) 1.43
Alu element mutation spectra: molecular clocks and the effect of DNA methylation. J Mol Biol (2004) 1.41
Mobile DNA elements in primate and human evolution. Am J Phys Anthropol (2007) 1.38
From the margins of the genome: mobile elements shape primate evolution. Bioessays (2005) 1.36
A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome. Semin Cancer Biol (2010) 1.34
Genome-wide analysis of the human Alu Yb-lineage. Hum Genomics (2004) 1.33
Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity. Proc Natl Acad Sci U S A (2006) 1.32
Chromosomal inversions between human and chimpanzee lineages caused by retrotransposons. PLoS One (2008) 1.32
Under the genomic radar: the stealth model of Alu amplification. Genome Res (2005) 1.31
Recently integrated Alu retrotransposons are essentially neutral residents of the human genome. Gene (2006) 1.31
Y chromosome STR haplotypes and the genetic structure of U.S. populations of African, European, and Hispanic ancestry. Genome Res (2003) 1.30
A mobile element based phylogeny of Old World monkeys. Mol Phylogenet Evol (2005) 1.30
Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome. Nucleic Acids Res (2007) 1.29
Non-traditional Alu evolution and primate genomic diversity. J Mol Biol (2002) 1.27
Different evolutionary fates of recently integrated human and chimpanzee LINE-1 retrotransposons. Gene (2006) 1.26
Identification and characterization of novel polymorphic LINE-1 insertions through comparison of two human genome sequence assemblies. Gene (2006) 1.24
Human DNA quantitation using Alu element-based polymerase chain reaction. Anal Biochem (2003) 1.24
Phylogeny of the macaques (Cercopithecidae: Macaca) based on Alu elements. Gene (2009) 1.21
Nuclear versus mitochondrial DNA: evidence for hybridization in colobine monkeys. BMC Evol Biol (2011) 1.21
A mobile element-based evolutionary history of guenons (tribe Cercopithecini). BMC Biol (2007) 1.18
Multiplex polymerase chain reaction for simultaneous quantitation of human nuclear, mitochondrial, and male Y-chromosome DNA: application in human identification. Anal Biochem (2005) 1.17
LINE-1 preTa elements in the human genome. J Mol Biol (2003) 1.16
HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging. Aging Cell (2010) 1.16
Allelic heterogeneity in LINE-1 retrotransposition activity. Am J Hum Genet (2003) 1.13
Molecular phylogenetic analyses of genus Crocodylus (Eusuchia, Crocodylia, Crocodylidae) and the taxonomic position of Crocodylus porosus. Mol Phylogenet Evol (2010) 1.12
Analysis of the human Alu Ya-lineage. J Mol Biol (2004) 1.12
Alu repeats increase local recombination rates. BMC Genomics (2009) 1.11
An alternative pathway for Alu retrotransposition suggests a role in DNA double-strand break repair. Genomics (2008) 1.11
Following the LINEs: an analysis of primate genomic variation at human-specific LINE-1 insertion sites. Mol Biol Evol (2003) 1.08
Inference of human geographic origins using Alu insertion polymorphisms. Forensic Sci Int (2005) 1.08
Identification of repeat structure in large genomes using repeat probability clouds. Anal Biochem (2008) 1.07
Comprehensive analysis of two Alu Yd subfamilies. J Mol Evol (2003) 1.06
Analysis of the human Alu Ye lineage. BMC Evol Biol (2005) 1.03
Centromere remodeling in Hoolock leuconedys (Hylobatidae) by a new transposable element unique to the gibbons. Genome Biol Evol (2012) 1.02
Tracking Alu evolution in New World primates. BMC Evol Biol (2005) 1.00
Reading TE leaves: new approaches to the identification of transposable element insertions. Genome Res (2011) 0.99