Published in Trends Biochem Sci on October 20, 2013
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A histone methylation network regulates transgenerational epigenetic memory in C. elegans. Cell Rep (2014) 1.01
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat Chem Biol (2016) 0.96
Pluripotency and Epigenetic Factors in Mouse Embryonic Stem Cell Fate Regulation. Mol Cell Biol (2015) 0.95
Histone target selection within chromatin: an exemplary case of teamwork. Genes Dev (2014) 0.95
Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy. Clin Epigenetics (2016) 0.95
Diverse functions of PHD fingers of the MLL/KMT2 subfamily. Biochim Biophys Acta (2013) 0.91
Genetic alterations of histone lysine methyltransferases and their significance in breast cancer. Oncotarget (2015) 0.90
Macromolecular transport between the nucleus and the cytoplasm: Advances in mechanism and emerging links to disease. Biochim Biophys Acta (2014) 0.89
Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma. PLoS One (2015) 0.84
Epigenomics of macrophages. Immunol Rev (2014) 0.84
Post-translational modifications are key players of the Legionella pneumophila infection strategy. Front Microbiol (2015) 0.84
Histone methyltransferases: novel targets for tumor and developmental defects. Am J Transl Res (2015) 0.82
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model. Clin Epigenetics (2016) 0.80
Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol (2016) 0.79
The selective activation of p53 target genes regulated by SMYD2 in BIX-01294 induced autophagy-related cell death. PLoS One (2015) 0.79
Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase. PLoS One (2015) 0.79
Transcription factors, chromatin proteins and the diversification of Hemiptera. Insect Biochem Mol Biol (2015) 0.79
Multiple levels of epigenetic control for bone biology and pathology. Bone (2015) 0.78
Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J Biol Chem (2015) 0.78
The METTL20 Homologue from Agrobacterium tumefaciens Is a Dual Specificity Protein-lysine Methyltransferase That Targets Ribosomal Protein L7/L12 and the β Subunit of Electron Transfer Flavoprotein (ETFβ). J Biol Chem (2016) 0.77
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife (2016) 0.77
Enhancer deregulation in cancer and other diseases. Bioessays (2016) 0.76
The complexity of epigenetic diseases. J Pathol (2015) 0.76
Intrinsic protein disorder in histone lysine methylation. Biol Direct (2016) 0.76
The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration. Skelet Muscle (2016) 0.76
A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin. J Biol Chem (2015) 0.76
An atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectual disability. Hum Genet (2016) 0.76
Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines. BMC Biotechnol (2016) 0.75
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Nat Chem Biol (2017) 0.75
Diversification and evolution of the SDG gene family in Brassica rapa after the whole genome triplication. Sci Rep (2015) 0.75
Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection. PLoS Pathog (2016) 0.75
The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Res (2017) 0.75
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL. Biol Open (2016) 0.75
Identification of SET Domain-Containing Proteins in Gossypium raimondii and Their Response to High Temperature Stress. Sci Rep (2016) 0.75
Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability. BMC Biochem (2016) 0.75
A System for Enzymatic Lysine Methylation in a Desired Sequence Context. ACS Omega (2017) 0.75
The expanding role of the Ehmt2/G9a complex in neurodevelopment. Neurogenesis (Austin) (2017) 0.75
An Overview of Chromatin-Regulating Proteins in Cells. Curr Protein Pept Sci (2016) 0.75
Recent progress in developing selective inhibitors of protein methyltransferases. Curr Opin Chem Biol (2017) 0.75
The winding path of protein methylation research: milestones and new frontiers. Nat Rev Mol Cell Biol (2017) 0.75
Comparative genomic analysis of SET-domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. Gigascience (2017) 0.75
High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A (2009) 20.66
Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet (2008) 18.28
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
The Polycomb complex PRC2 and its mark in life. Nature (2011) 11.97
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell (2001) 11.39
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell (2003) 11.33
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature (2008) 10.95
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev (2002) 10.54
Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol (2009) 9.29
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev (2002) 8.78
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev (2004) 8.66
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell (2009) 8.62
The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol (2007) 8.57
Differential chromatin marking of introns and expressed exons by H3K36me3. Nat Genet (2009) 8.11
Regulation of alternative splicing by histone modifications. Science (2010) 7.98
The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol (2001) 7.20
Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell (2008) 6.86
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol (2003) 6.79
Role of the polycomb protein EED in the propagation of repressive histone marks. Nature (2009) 6.62
Altered Hox expression and segmental identity in Mll-mutant mice. Nature (1995) 6.60
Chromatin organization marks exon-intron structure. Nat Struct Mol Biol (2009) 5.90
Regulation of p53 activity through lysine methylation. Nature (2004) 5.78
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J (2002) 5.70
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet (2009) 5.52
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev (2005) 5.50
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol (2002) 5.42
Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet (2012) 5.42
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell (2004) 5.06
CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature (2010) 4.86
Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development (2007) 4.80
SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nat Cell Biol (2004) 4.72
Repression of p53 activity by Smyd2-mediated methylation. Nature (2006) 4.51
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell (2003) 4.49
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell (2007) 4.49
Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. Mol Cell (2008) 4.44
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet (2008) 4.40
Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2. Mol Cell (2010) 4.36
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
Retracted Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature (2002) 4.18
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (2010) 3.97
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation. Genes Dev (2003) 3.95
The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. J Biol Chem (2003) 3.81
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation. EMBO J (2007) 3.81
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science (2005) 3.80
Biased chromatin signatures around polyadenylation sites and exons. Mol Cell (2009) 3.74
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (2012) 3.74
Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin. Science (2007) 3.69
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive. Nature (2007) 3.68
Modulation of p53 function by SET8-mediated methylation at lysine 382. Mol Cell (2007) 3.68
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet (2003) 3.64
The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Annu Rev Biochem (2012) 3.61
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell (2004) 3.60
Protein lysine methyltransferase G9a acts on non-histone targets. Nat Chem Biol (2008) 3.53
Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation. Mol Cell (2008) 3.53
Understanding the language of Lys36 methylation at histone H3. Nat Rev Mol Cell Biol (2012) 3.52
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell (2007) 3.51
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. Genes Dev (2010) 3.49
Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development (1992) 3.47
Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites. EMBO J (2008) 3.40
A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. Cell (2009) 3.36
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing. Development (2009) 3.34
Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature (2007) 3.32
Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development (2006) 3.28
Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics (1990) 3.27
A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell (2010) 3.27
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol (2009) 3.26
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules. Nat Struct Mol Biol (2008) 3.20
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev (2008) 3.16
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. PLoS One (2010) 3.15
Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell (2011) 3.14
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature (2011) 3.10
Retracted GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Nature (2009) 3.10
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev (2004) 3.08
H3K9 methyltransferase G9a and the related molecule GLP. Genes Dev (2011) 3.01
The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Mol Cell Biol (2011) 3.01
Polycomb group protein ezh2 controls actin polymerization and cell signaling. Cell (2005) 3.01
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell (2003) 2.97
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo. Mol Cell Biol (2008) 2.93
Histone H3-K9 methyltransferase ESET is essential for early development. Mol Cell Biol (2004) 2.92
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol Cell (2005) 2.89
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell (2010) 2.89
MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol Cell (2007) 2.87
Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol Cell (2012) 2.85
The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains. Proc Natl Acad Sci U S A (1990) 2.85
Asymmetrically modified nucleosomes. Cell (2012) 2.79
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. Mol Cell (2007) 2.77
Polycomb response elements and targeting of Polycomb group proteins in Drosophila. Curr Opin Genet Dev (2006) 2.76
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature (2007) 2.76
The histone methyltransferase SET8 is required for S-phase progression. J Cell Biol (2007) 2.74
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature (2009) 2.74
Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. Cell (2012) 2.67
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol (2010) 2.64
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature (2006) 24.29
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell (2003) 7.47
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol (2003) 6.79
New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell (2006) 5.14
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev (2003) 5.13
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol (2002) 5.04
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol Cell (2010) 4.99
Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem (2002) 4.75
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell (2003) 4.49
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell (2007) 4.49
An operational definition of epigenetics. Genes Dev (2009) 4.26
Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol (2007) 4.17
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem (2002) 4.05
Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature (2009) 3.83
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell (2009) 3.82
The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p. J Biol Chem (2003) 3.81
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell (2005) 3.66
Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes. Nat Struct Mol Biol (2006) 3.54
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol (2009) 3.26
The language of histone crosstalk. Cell (2010) 3.18
Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Mol Cell (2009) 2.91
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol Cell (2005) 2.89
Histone modification: cause or cog? Trends Genet (2011) 2.85
Transcriptional elongation by RNA polymerase II and histone methylation. J Biol Chem (2003) 2.76
The super elongation complex (SEC) and MLL in development and disease. Genes Dev (2011) 2.63
Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes Dev (2010) 2.53
Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell (2011) 2.53
Rtt109 is required for proper H3K56 acetylation: a chromatin mark associated with the elongating RNA polymerase II. J Biol Chem (2006) 2.45
Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. Mol Cell Biol (2008) 2.34
Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein. Cell (2007) 2.29
Histone H3 lysine 4 (H3K4) methylation in development and differentiation. Dev Biol (2009) 2.24
Cse4 is part of an octameric nucleosome in budding yeast. Mol Cell (2009) 2.23
A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation. Nat Struct Mol Biol (2008) 2.22
The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes. Mol Cell (2010) 2.06
The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase. Nat Struct Mol Biol (2007) 2.05
Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Genes Dev (2012) 2.04
The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS. Mol Cell (2005) 1.99
Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription. J Biol Chem (2009) 1.94
Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol (2007) 1.89
A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: linking leukemogensis to covalent modifications of chromatin. J Cell Biochem (2005) 1.88
The super elongation complex (SEC) family in transcriptional control. Nat Rev Mol Cell Biol (2012) 1.78
A site to remember: H3K36 methylation a mark for histone deacetylation. Mutat Res (2007) 1.77
Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC). Genes Dev (2011) 1.77
Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis. Nat Rev Cancer (2010) 1.77
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proc Natl Acad Sci U S A (2005) 1.69
The COMPASS family of H3K4 methylases in Drosophila. Mol Cell Biol (2011) 1.54
Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling. Proc Natl Acad Sci U S A (2006) 1.54
Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1. J Cell Biol (2009) 1.52
WDR5, a complexed protein. Nat Struct Mol Biol (2009) 1.51
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Mol Cell (2005) 1.51
Ctk complex-mediated regulation of histone methylation by COMPASS. Mol Cell Biol (2006) 1.50
The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Mol Cell Biol (2012) 1.49
Leaving a mark: the many footprints of the elongating RNA polymerase II. Curr Opin Genet Dev (2006) 1.46
Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Mol Genet Genomics (2006) 1.42
The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers. Mol Cell Biol (2013) 1.35
dELL is an essential RNA polymerase II elongation factor with a general role in development. Proc Natl Acad Sci U S A (2002) 1.34
The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation. Cell (2012) 1.33
Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Mol Cell Biol (2008) 1.32
Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Mol Cell (2011) 1.32
The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Mol Cell Biol (2010) 1.32
Bur1/Bur2 and the Ctk complex in yeast: the split personality of mammalian P-TEFb. Cell Cycle (2006) 1.31
Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL. Proc Natl Acad Sci U S A (2008) 1.30
Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123. Genes Dev (2011) 1.30
Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Mol Cell Biol (2007) 1.26
Multiple mixed lineage leukemia (MLL) fusion proteins suppress p53-mediated response to DNA damage. J Biol Chem (2005) 1.23
Cross-talking histones: implications for the regulation of gene expression and DNA repair. Biochem Cell Biol (2005) 1.22
The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells. Nat Struct Mol Biol (2013) 1.21
The JARID2-PRC2 duality. Genes Dev (2010) 1.18
Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1. Mol Cell Biol (2009) 1.18
Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation. Nat Cell Biol (2005) 1.15
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling. Science (2014) 1.13
Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human. Proc Natl Acad Sci U S A (2011) 1.12
Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Mol Cell Biol (2012) 1.10
Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1. Genes Dev (2012) 1.09
Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. J Biol Chem (2004) 1.08
Global proteomic analysis of S. cerevisiae (GPS) to identify proteins required for histone modifications. Methods Enzymol (2004) 1.07
The little elongation complex regulates small nuclear RNA transcription. Mol Cell (2011) 1.06
Molecular basis of p53 functional inactivation by the leukemic protein MLL-ELL. Mol Cell Biol (2003) 1.04
Histone demethylation by hydroxylation: chemistry in action. ACS Chem Biol (2006) 1.01
In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Mol Cell Biol (2004) 1.01
Transcriptional elongation checkpoint control in development and disease. Genes Dev (2013) 0.98
SnapShot: Histone lysine methylase complexes. Cell (2012) 0.92
Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation. Genes Dev (2014) 0.91
Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster. Mol Cell Biol (2005) 0.90
Developmental biology. Histone cross-talk in stem cells. Science (2009) 0.88
Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. Mol Cell Biol (2013) 0.87
The curious case of bivalent marks. Dev Cell (2009) 0.87
The little elongation complex functions at initiation and elongation phases of snRNA gene transcription. Mol Cell (2013) 0.86
Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche. Development (2013) 0.86
A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast. Mol Cell Biol (2011) 0.85
The A, B, Gs of silencing. Genes Dev (2007) 0.84
Posttranslational modifications of histones by methylation. Adv Protein Chem (2004) 0.81
Packing for the germy: the role of histone H4 Ser1 phosphorylation in chromatin compaction and germ cell development. Genes Dev (2006) 0.81
Structural basis for H3K4 trimethylation by yeast Set1/COMPASS. Adv Enzyme Regul (2009) 0.79
Transcriptional blackjack with p21. Genes Dev (2006) 0.78
Guided by COMPASS on a journey through chromosome segregation. Nat Struct Mol Biol (2005) 0.78
Preparation and assay of RNA polymerase II elongation factors elongin and ELL. Methods Enzymol (2003) 0.77
Medicine. (Poly)combing the pediatric cancer genome for answers. Science (2013) 0.77
A histone modifier's ill-gotten copy gains. Cell (2013) 0.76