Published in J Biol Chem on April 19, 2010
DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs. Cell Stem Cell (2011) 3.10
Naive pluripotency is associated with global DNA hypomethylation. Nat Struct Mol Biol (2013) 2.49
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet (2015) 2.04
DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. Dev Cell (2016) 1.51
hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cells. PLoS Genet (2015) 1.49
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc Natl Acad Sci U S A (2013) 1.32
De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET. Development (2013) 1.23
Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms. PLoS Genet (2011) 1.18
Assisted reproduction treatment and epigenetic inheritance. Hum Reprod Update (2012) 1.11
RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells. Mol Cell Biol (2012) 1.08
Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells. Epigenetics Chromatin (2013) 1.08
Citrullination of histone H3 interferes with HP1-mediated transcriptional repression. PLoS Genet (2012) 1.04
Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1. Proc Natl Acad Sci U S A (2014) 1.04
Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells. PLoS Comput Biol (2012) 1.02
The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation. Cell Stem Cell (2015) 1.02
Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline. Cell Mol Life Sci (2013) 0.97
Atrx promotes heterochromatin formation at retrotransposons. EMBO Rep (2015) 0.94
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol (2012) 0.93
TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells. Cell Rep (2014) 0.91
Retrotransposon-based profiling of mammalian epigenomes: DNA methylation of IAP LTRs in embryonic stem, somatic and cancer cells. Genomics (2014) 0.91
Epigenetic stability, adaptability, and reversibility in human embryonic stem cells. Proc Natl Acad Sci U S A (2012) 0.89
The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice. Hum Mol Genet (2013) 0.87
How retrotransposons shape genome regulation. Curr Opin Genet Dev (2016) 0.85
H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing. Epigenetics Chromatin (2011) 0.85
Retrotransposons shape species-specific embryonic stem cell gene expression. Retrovirology (2015) 0.84
Vaccination with Ad5 vectors expands Ad5-specific CD8 T cells without altering memory phenotype or functionality. PLoS One (2010) 0.82
Restricting retrotransposons: a review. Mob DNA (2016) 0.79
Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Hum Mol Genet (2014) 0.76
Adaption by Rewiring Epigenetic Landscapes. Cell Stem Cell (2015) 0.75
Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype. Sci Rep (2016) 0.75
Heterochromatic histone modifications at transposons in Xenopus tropicalis embryos. Dev Biol (2016) 0.75
Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (2003) 25.57
Eukaryotic cytosine methyltransferases. Annu Rev Biochem (2005) 15.45
New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature (2007) 13.54
Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci (2006) 13.32
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev (2005) 12.15
Genome regulation by polycomb and trithorax proteins. Cell (2007) 11.96
Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature (2007) 11.72
The DNA methyltransferases of mammals. Hum Mol Genet (2000) 10.66
Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet (2002) 9.16
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res (2005) 8.69
Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development (1996) 7.98
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet (1998) 7.49
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis (2003) 5.19
DNA methylation in health and disease. Nat Rev Genet (2000) 4.58
KAP1 controls endogenous retroviruses in embryonic stem cells. Nature (2010) 4.02
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature (2010) 3.55
Retrotransposons as epigenetic mediators of phenotypic variation in mammals. Nat Genet (2001) 3.05
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci (2001) 2.75
Nucleotide sequence of a complete mouse intracisternal A-particle genome: relationship to known aspects of particle assembly and function. J Virol (1987) 2.57
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53
The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. Cell (2006) 2.47
Retrotransposition of a mouse IAP sequence tagged with an indicator gene. Cell (1991) 2.34
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol Cell Biol (2002) 2.24
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development (2005) 2.08
The extraction of intracisternal A-particles from a mouse plasma-cell tumor. Cancer Res (1968) 1.99
Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells. Nat Genet (2004) 1.87
Dnmt1 expression in pre- and postimplantation embryogenesis and the maintenance of IAP silencing. Mol Cell Biol (2004) 1.86
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68
Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res (2007) 1.59
Methylation dynamics of repetitive DNA elements in the mouse germ cell lineage. Genomics (2003) 1.58
One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation. Genomics (2007) 1.56
Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice. Mol Cell Biol (1996) 1.52
Intracisternal A-particle gene expression in normal mouse thymus tissue: gene products and strain-related variability. Mol Cell Biol (1985) 1.28
Immunological relationship between the structural proteins of intracisternal A-particles of Mus musculus and the M432 retrovirus of Mus cervicolor. J Virol (1980) 1.18
Negative and positive effects of an IAP-LTR on nearby Pcdaalpha gene expression in the central nervous system and neuroblastoma cell lines. Gene (2004) 0.88
Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events. J Virol (1999) 0.87
The expression of intracisternal A particle genes in the preimplantation mouse embryo. Dev Biol (1991) 0.85
Formation of an active form of the interleukin-2/15 receptor beta-chain by insertion of the intracisternal A particle in a radiation-induced mouse thymic lymphoma and its role in tumorigenesis. Mol Carcinog (2003) 0.85
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells. Reprod Biol Endocrinol (2006) 0.84
PANG, a gene encoding a neuronal glycoprotein, is ectopically activated by intracisternal A-type particle long terminal repeats in murine plasmacytomas. Proc Natl Acad Sci U S A (1994) 0.83
Intracisternal A particles in preimplantation embryos of feral mice (Mus musculus). Intervirology (1979) 0.79
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science (2003) 8.81
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell (2008) 5.40
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci (2010) 5.12
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature (2013) 3.06
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev (2009) 2.95
Control of iron homeostasis by an iron-regulated ubiquitin ligase. Science (2009) 2.60
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53
Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell (2011) 2.49
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res (2005) 2.42
CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. Proc Natl Acad Sci U S A (2008) 2.36
A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci (2005) 2.30
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Hum Mol Genet (2006) 2.27
Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC Genomics (2009) 2.15
A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol (2008) 2.12
BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat Cell Biol (2009) 2.04
The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol (2009) 1.89
DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68
Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res (2007) 1.59
Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation. J Neurosci Res (2002) 1.58
Hydrogel matrix to support stem cell survival after brain transplantation in stroke. Neurorehabil Neural Repair (2010) 1.50
Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell (2013) 1.40
Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells. Hum Mol Genet (2010) 1.40
Copy number variant analysis of human embryonic stem cells. Stem Cells (2008) 1.29
The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression. Science (2010) 1.27
A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples. Anal Biochem (2011) 1.26
Functional modules distinguish human induced pluripotent stem cells from embryonic stem cells. Stem Cells Dev (2011) 1.15
Variations of X chromosome inactivation occur in early passages of female human embryonic stem cells. PLoS One (2010) 1.13
Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus Relat Syst (2005) 1.11
DNA methylation in cell differentiation and reprogramming: an emerging systematic view. Regen Med (2010) 1.04
Fetuin A stabilizes m-calpain and facilitates plasma membrane repair. J Biol Chem (2007) 1.01
Epigenetic regulation of X-inactivation in human embryonic stem cells. Epigenetics (2009) 0.96
Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells. Hum Mol Genet (2012) 0.95
Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex. Mol Cell Biol (2011) 0.95
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol (2012) 0.93
Early prenatal diagnosis of semilobar holoprosencephaly combined with a dorsal cyst and no facial defect. Taiwan J Obstet Gynecol (2008) 0.93
Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. J Neurosci Res (2012) 0.93
Vaginal disinfection with povidone iodine immediately before oocyte retrieval is effective in preventing pelvic abscess formation without compromising the outcome of IVF-ET. J Assist Reprod Genet (2005) 0.91
Increased short-term food satiation and sensitivity to cholecystokinin in neurotrophin-4 knock-in mice. Am J Physiol Regul Integr Comp Physiol (2004) 0.88
Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells. PLoS One (2012) 0.88
Cyclophilin a protects Peg3 from hypermethylation and inactive histone modification. J Biol Chem (2006) 0.87
Quantitative analysis of rhegmatogenous retinal detachment associated with choroidal detachment in Chinese using UBM. Retina (2012) 0.84
Juvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories. Front Behav Neurosci (2012) 0.84
Endoprotease-mediated intracellular protein delivery using nanocapsules. ACS Nano (2011) 0.84
Evaluation of x-inactivation status and cytogenetic stability of human dermal fibroblasts after long-term culture. Int J Cell Biol (2010) 0.82
Comparison of the effect of two different doses of recombinant gonadotropin for ovarian stimulation on the outcome of intrauterine insemination. Taiwan J Obstet Gynecol (2011) 0.80
hsBAFF enhances activity of NK cells by regulation of CD4(+) T lymphocyte function. Immunol Lett (2008) 0.78
Polyethylene glycol-based protein nanocapsules for functional delivery of a differentiation transcription factor. Biomaterials (2012) 0.78
Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Vis Neurosci (2005) 0.78
Short-term postoperative GnRH analogue or danazol treatment after conservative surgery for stage III or IV endometriosis before ovarian stimulation: a prospective, randomized study. J Reprod Med (2004) 0.77
Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus. J Cereb Blood Flow Metab (2003) 0.77
Genome-wide DNA methylation profiling: the mDIP-chip technology. Methods Mol Biol (2009) 0.75
Stem cell-based therapy of corneal epithelial and endothelial diseases. Regen Med (2015) 0.75
Epigenetic modifications in distinction: histone versus DNA methylation in ESCs. Cell Stem Cell (2011) 0.75
Observation of persistent fundus fluorescence after internal limiting membrane peeling assisted by indocyanine green solution of different concentrations. Eye Sci (2011) 0.75
Dengue virus infection in early gestation with delivery of an unaffected fetus and no vertical transmission. Taiwan J Obstet Gynecol (2010) 0.75
Influence of pituitary suppression with triphasic or monophasic oral contraceptives on the outcome of in vitro fertilization and embryo transfer. J Assist Reprod Genet (2006) 0.75
Marangoni effect-driven motion of miniature robots and generation of electricity on water. Langmuir (2017) 0.75
Atypical ovarian hyperstimulation syndrome with isolated pleural effusion but without ascites or hemoconcentration. Taiwan J Obstet Gynecol (2007) 0.75
Erratum: Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. Nat Immunol (2016) 0.75
[Vitreous levels of stromal cell-derived factor-1 and vascular endothelial growth factor in diabetic retinopathy]. Yan Ke Xue Bao (2008) 0.75
Hyperbranched polymers and dendrimers as templates for organic/inorganic hybrid nanomaterials. J Nanosci Nanotechnol (2014) 0.75