Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 3465630)

Published in J Invest Dermatol on July 05, 2012

Authors

Ji Li1, Ting-Xin Jiang, Michael W Hughes, Ping Wu, Juehua Yu, Randall B Widelitz, Guoping Fan, Cheng-Ming Chuong

Author Affiliations

1: Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Articles citing this

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging. Cell Rep (2013) 2.19

Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease. Cell Stem Cell (2015) 0.94

Cellular mechanisms of somatic stem cell aging. Curr Top Dev Biol (2014) 0.90

Epigenetic control of skin and hair regeneration after wounding. Exp Dermatol (2014) 0.89

Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration. Hear Res (2012) 0.89

Epigenetic control of adult stem cell function. Nat Rev Mol Cell Biol (2016) 0.88

Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration. Exp Dermatol (2014) 0.83

DNA methylation as a dynamic regulator of development and disease processes: spotlight on the prostate. Epigenomics (2015) 0.81

Deciphering principles of morphogenesis from temporal and spatial patterns on the integument. Dev Dyn (2015) 0.81

The Yin and Yang of Chromatin Dynamics In Stem Cell Fate Selection. Trends Genet (2015) 0.81

Many paths to alopecia via compromised regeneration of hair follicle stem cells. J Invest Dermatol (2013) 0.77

Epidermal stem cells and their epigenetic regulation. Int J Mol Sci (2013) 0.77

miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1. Cell Death Dis (2017) 0.75

Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ. Elife (2017) 0.75

The Role of p16(INK4a) Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and Cancer. Int J Mol Sci (2017) 0.75

Articles cited by this

Epigenetics: a landscape takes shape. Cell (2007) 8.29

Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92

Controls of hair follicle cycling. Physiol Rev (2001) 5.49

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature (2008) 4.67

Epithelial stem cells: a folliculocentric view. J Invest Dermatol (2006) 3.49

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46

Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells. Blood (1991) 3.12

Molecular principles of hair follicle induction and morphogenesis. Bioessays (2005) 3.08

DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci (2001) 2.75

DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature (2010) 2.74

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev (2011) 2.63

beta-catenin activity in the dermal papilla regulates morphogenesis and regeneration of hair. Dev Cell (2010) 2.60

Recruitment of DNA methyltransferase I to DNA repair sites. Proc Natl Acad Sci U S A (2005) 2.50

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol (2007) 2.47

Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells. Cell Stem Cell (2009) 2.45

Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science (2011) 1.96

Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. J Cell Biol (1986) 1.91

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest (2011) 1.81

Complex hair cycle domain patterns and regenerative hair waves in living rodents. J Invest Dermatol (2008) 1.70

Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Mol Cell Biochem (2003) 1.45

Molecular biology of hair morphogenesis: development and cycling. J Exp Zool B Mol Dev Evol (2003) 1.36

Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci U S A (2006) 1.35

Repression of retrotransposal elements in mouse embryonic stem cells is primarily mediated by a DNA methylation-independent mechanism. J Biol Chem (2010) 1.33

Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression. J Histochem Cytochem (2002) 1.26

Genetic basis of skin appendage development. Semin Cell Dev Biol (2007) 1.20

Epithelial-specific requirement of FGFR2 signaling during tooth and palate development. J Exp Zool B Mol Dev Evol (2009) 1.02

From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis. Differentiation (2011) 0.89

Articles by these authors

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature (2004) 12.41

Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA (2006) 11.71

DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science (2003) 8.81

Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators. PLoS Med (2006) 8.57

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell (2008) 5.40

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med (2011) 5.16

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci (2010) 5.12

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature (2008) 4.67

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncol (2006) 4.32

A memory retrieval-extinction procedure to prevent drug craving and relapse. Science (2012) 4.04

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. BMJ (2009) 3.39

Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients. J Am Coll Cardiol (2008) 3.33

Validity of composite end points in clinical trials. BMJ (2005) 3.26

Transfusion-related acute lung injury: incidence and risk factors. Blood (2011) 3.12

SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell (2007) 3.09

Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ (2007) 3.06

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature (2013) 3.06

Cardiovascular events associated with smoking cessation pharmacotherapies: a network meta-analysis. Circulation (2013) 2.73

Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science (2009) 2.68

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53

Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell (2011) 2.49

Psychopathology among New York city public school children 6 months after September 11. Arch Gen Psychiatry (2005) 2.48

Statin therapy in stroke prevention: a meta-analysis involving 121,000 patients. Am J Med (2008) 2.44

Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res (2005) 2.42

The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement. Contemp Clin Trials (2005) 2.40

CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. Proc Natl Acad Sci U S A (2008) 2.36

TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med (2008) 2.33

A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci (2005) 2.30

Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Hum Mol Genet (2006) 2.27

Molecular shaping of the beak. Science (2004) 2.24

ARL1, a LOB-domain protein required for adventitious root formation in rice. Plant J (2005) 2.24

Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials. Am J Med (2012) 2.23

Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC Genomics (2009) 2.15

Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. Diabetes Res Clin Pract (2013) 2.12

OsPHR2 is involved in phosphate-starvation signaling and excessive phosphate accumulation in shoots of plants. Plant Physiol (2008) 2.06

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat Cell Biol (2009) 2.04

An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol (2007) 2.03

Design, analysis, and presentation of crossover trials. Trials (2009) 2.01

Two rice phosphate transporters, OsPht1;2 and OsPht1;6, have different functions and kinetic properties in uptake and translocation. Plant J (2008) 1.97

Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science (2011) 1.96

Shift of localized growth zones contributes to skin appendage morphogenesis: role of the Wnt/beta-catenin pathway. J Invest Dermatol (2003) 1.95

The morphogenesis of feathers. Nature (2002) 1.91

Posttreatment with aspirin-triggered lipoxin A4 analog attenuates lipopolysaccharide-induced acute lung injury in mice: the role of heme oxygenase-1. Anesth Analg (2007) 1.91

An analysis of general medical and specialist journals that endorse CONSORT found that reporting was not enforced consistently. J Clin Epidemiol (2005) 1.89

The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol (2009) 1.89

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Invest (2009) 1.89

Evo-Devo of amniote integuments and appendages. Int J Dev Biol (2004) 1.84

Defining dermal adipose tissue. Exp Dermatol (2014) 1.84

A PIN1 family gene, OsPIN1, involved in auxin-dependent adventitious root emergence and tillering in rice. Plant Cell Physiol (2005) 1.79

Developmental biology. The Turing model comes of molecular age. Science (2006) 1.77

DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76

OsPTF1, a novel transcription factor involved in tolerance to phosphate starvation in rice. Plant Physiol (2005) 1.76

A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Sci Transl Med (2011) 1.75

Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis. Clin Immunol (2012) 1.74

Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol (2004) 1.72

Cell wall polysaccharides are specifically involved in the exclusion of aluminum from the rice root apex. Plant Physiol (2007) 1.72

Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial. Lancet Oncol (2011) 1.71

Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators. J Biol Chem (2002) 1.71

Complex hair cycle domain patterns and regenerative hair waves in living rodents. J Invest Dermatol (2008) 1.70

'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70

Adaptation to the sky: Defining the feather with integument fossils from mesozoic China and experimental evidence from molecular laboratories. J Exp Zool B Mol Dev Evol (2003) 1.69

Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab. J Biol Chem (2005) 1.69

DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68

Physiological and transcriptome analysis of iron and phosphorus interaction in rice seedlings. Plant Physiol (2009) 1.65

Photoperiod- and thermo-sensitive genic male sterility in rice are caused by a point mutation in a novel noncoding RNA that produces a small RNA. Cell Res (2012) 1.63

New Early Cretaceous fossil from China documents a novel trophic specialization for Mesozoic birds. Naturwissenschaften (2003) 1.63

Characterization of a sub-family of Arabidopsis genes with the SPX domain reveals their diverse functions in plant tolerance to phosphorus starvation. Plant J (2008) 1.60

Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res (2007) 1.59

Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation. J Neurosci Res (2002) 1.58

Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis. Ann Med (2012) 1.54

Involvement of OsSPX1 in phosphate homeostasis in rice. Plant J (2008) 1.53

Iron deficiency-induced secretion of phenolics facilitates the reutilization of root apoplastic iron in red clover. Plant Physiol (2007) 1.53

Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. Proc Natl Acad Sci U S A (2013) 1.52

Occupational exposure to welding fume among welders: alterations of manganese, iron, zinc, copper, and lead in body fluids and the oxidative stress status. J Occup Environ Med (2004) 1.52

NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3. Am J Physiol Lung Cell Mol Physiol (2008) 1.52

Distribution and characterization of over 1000 T-DNA tags in rice genome. Plant J (2003) 1.50

Hydrogel matrix to support stem cell survival after brain transplantation in stroke. Neurorehabil Neural Repair (2010) 1.50

Determining the reporting quality of RCTs in clinical pharmacology. Br J Clin Pharmacol (2004) 1.49

The phosphate transporter gene OsPht1;8 is involved in phosphate homeostasis in rice. Plant Physiol (2011) 1.48

Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci (2013) 1.48

OsSPX1 suppresses the function of OsPHR2 in the regulation of expression of OsPT2 and phosphate homeostasis in shoots of rice. Plant J (2010) 1.48

Knowledge, perceptions and information about hormone therapy (HT) among menopausal women: a systematic review and meta-synthesis. PLoS One (2011) 1.48

Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biol Psychiatry (2009) 1.48

The emerging importance of the SPX domain-containing proteins in phosphate homeostasis. New Phytol (2012) 1.47

Mapping stem cell activities in the feather follicle. Nature (2005) 1.44

Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J (2007) 1.43

The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes. Structure (2006) 1.43

Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J Biol Chem (2006) 1.43

The biology of feather follicles. Int J Dev Biol (2004) 1.41