Published in EMBO J on April 30, 2010
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Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans. Nat Struct Mol Biol (2010) 4.22
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol Cell (2005) 3.97
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Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature (2009) 2.56
Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity. Genome Res (2008) 2.52
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Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell (2009) 2.28
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PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli. Mol Cell (2004) 1.69
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The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation. Cell Cycle (2008) 1.07
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Unlocking the secrets of the genome. Nature (2009) 11.80
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature (2007) 11.66
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res (2007) 9.61
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell (2007) 7.70
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Mammalian mirtron genes. Mol Cell (2007) 5.75
Endogenous RNA interference provides a somatic defense against Drosophila transposons. Curr Biol (2008) 5.22
The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature (2008) 5.05
The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution. Nat Struct Mol Biol (2008) 4.88
let-7 microRNAs in development, stem cells and cancer. Trends Mol Med (2008) 4.29
Virus discovery by deep sequencing and assembly of virus-derived small silencing RNAs. Proc Natl Acad Sci U S A (2010) 3.92
Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo. Nature (2010) 3.44
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol (2008) 3.40
miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling. Proc Natl Acad Sci U S A (2011) 3.35
Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature (2009) 3.03
Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell (2009) 3.02
Endogenous small interfering RNAs in animals. Nat Rev Mol Cell Biol (2008) 3.00
Widespread regulatory activity of vertebrate microRNA* species. RNA (2010) 2.97
Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet (2010) 2.84
Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol Cell (2011) 2.73
A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol (2009) 2.69
Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line. Genome Res (2009) 2.68
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci U S A (2010) 2.67
Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development. Proc Natl Acad Sci U S A (2005) 2.62
Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Res (2010) 2.56
Diversity and dynamics of the Drosophila transcriptome. Nature (2014) 2.47
Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes Dev (2008) 2.35
Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins. EMBO J (2009) 2.32
Vive la différence: biogenesis and evolution of microRNAs in plants and animals. Genome Biol (2011) 2.21
The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings. Genes Dev (2005) 2.04
Global patterns of tissue-specific alternative polyadenylation in Drosophila. Cell Rep (2012) 1.99
Adult-specific functions of animal microRNAs. Nat Rev Genet (2013) 1.89
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans. Nat Methods (2010) 1.82
MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila. Mol Cell (2010) 1.78
Target-mediated protection of endogenous microRNAs in C. elegans. Dev Cell (2011) 1.74
Widespread and extensive lengthening of 3' UTRs in the mammalian brain. Genome Res (2013) 1.72
Discovery of hundreds of mirtrons in mouse and human small RNA data. Genome Res (2012) 1.63
Dicing of viral replication intermediates during silencing of latent Drosophila viruses. Proc Natl Acad Sci U S A (2009) 1.61
Evolution of mir-92a underlies natural morphological variation in Drosophila melanogaster. Curr Biol (2013) 1.56
Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proc Natl Acad Sci U S A (2007) 1.53
The evolution and functional diversification of animal microRNA genes. Cell Res (2008) 1.49
Homeostatic control of Argonaute stability by microRNA availability. Nat Struct Mol Biol (2013) 1.42
Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. Science (2008) 1.41
The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs. Cell Cycle (2008) 1.38
Molecular biology: the expanding world of small RNAs. Nature (2008) 1.35
microRNA control of cell-cell signaling during development and disease. Cell Cycle (2008) 1.32
Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Genome Res (2010) 1.31
Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion. Proc Natl Acad Sci U S A (2005) 1.28
The liver-specific microRNA miR-122: biology and therapeutic potential. Prog Drug Res (2011) 1.26
miR-9a prevents apoptosis during wing development by repressing Drosophila LIM-only. Dev Biol (2009) 1.25
Mirtrons: microRNA biogenesis via splicing. Biochimie (2011) 1.24
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Lessons from microRNA mutants in worms, flies and mice. Cell Cycle (2008) 1.20
A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. Development (2012) 1.16
Regulating the regulators: mechanisms controlling the maturation of microRNAs. Trends Biotechnol (2008) 1.16
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol (2008) 1.13
The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans. Mol Cell (2013) 1.13
A Drosophila pasha mutant distinguishes the canonical microRNA and mirtron pathways. Mol Cell Biol (2008) 1.13
MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway. Nat Cell Biol (2013) 1.11
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep (2003) 1.09
Functional parameters of Dicer-independent microRNA biogenesis. RNA (2012) 1.08
The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation. Cell Cycle (2008) 1.07
Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks. Genetics (2009) 1.05
Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2. Nature (2011) 1.05
R2D2 organizes small regulatory RNA pathways in Drosophila. Mol Cell Biol (2010) 1.04
The Drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction. Neuron (2010) 1.04
Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals. Genes Dev (2013) 1.01
The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors. Genes Dev (2013) 1.00
A view from Drosophila: multiple biological functions for individual microRNAs. Semin Cell Dev Biol (2010) 0.99
RNase III-independent microRNA biogenesis in mammalian cells. RNA (2012) 0.96
A Drosophila genetic screen yields allelic series of core microRNA biogenesis factors and reveals post-developmental roles for microRNAs. RNA (2011) 0.96
Transgenic inhibitors of RNA interference in Drosophila. Fly (Austin) (2007) 0.95
Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects. PLoS One (2010) 0.94
Drosophila piwi mutants exhibit germline stem cell tumors that are sustained by elevated Dpp signaling. Curr Biol (2013) 0.92
Insensitive is a corepressor for Suppressor of Hairless and regulates Notch signalling during neural development. EMBO J (2011) 0.91
Control of microRNA biogenesis and transcription by cell signaling pathways. Curr Opin Genet Dev (2011) 0.91
BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells. Development (2013) 0.88
Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth by increasing apoptosis. Anticancer Agents Med Chem (2011) 0.88
Drosophila Argonaute 1 and its miRNA biogenesis partners are required for oocyte formation and germline cell division. Dev Biol (2012) 0.87
Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. PLoS Genet (2012) 0.87
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The impact of age, biogenesis, and genomic clustering on Drosophila microRNA evolution. RNA (2013) 0.85
The miR-310/13 cluster antagonizes β-catenin function in the regulation of germ and somatic cell differentiation in the Drosophila testis. Development (2013) 0.84
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The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans. Nucleic Acids Res (2011) 0.80
Intertwined pathways for Argonaute-mediated microRNA biogenesis in Drosophila. Nucleic Acids Res (2013) 0.79
RNA silencing in Monterey. Development (2011) 0.77
A deathly DNase activity for dicer. Dev Cell (2010) 0.76
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RNAi in Xenopus: look before you leap. Genes Dev (2011) 0.75