Published in J Biol Chem on June 15, 2010
Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A (1971) 31.05
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med (1991) 10.87
A mouse for all reasons. Cell (2007) 9.01
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell (2005) 7.29
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol (2009) 6.43
Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet (2001) 5.67
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell (1994) 5.41
Mosaic analysis with double markers in mice. Cell (2005) 5.32
The helix-loop-helix gene E2A is required for B cell formation. Cell (1994) 4.59
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Cre-mediated chromosome loss in mice. Nat Genet (1997) 3.36
Testing gene function early in the B cell lineage in mb1-cre mice. Proc Natl Acad Sci U S A (2006) 3.32
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods (2005) 2.70
Identification of the earliest B lineage stage in mouse bone marrow. Immunity (1996) 2.62
The Mouse Genome Database: enhancements and updates. Nucleic Acids Res (2009) 2.44
A new partner for the international knockout mouse consortium. Cell (2007) 2.23
Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells. Nat Genet (2001) 2.14
Engineering chromosomal rearrangements in mice. Nat Rev Genet (2001) 1.85
Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. Immunity (2007) 1.68
An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. J Immunol (2002) 1.52
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. J Immunol (2007) 1.36
The influence of S17 stromal cells and interleukin 7 on B cell development. Eur J Immunol (1990) 1.35
Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM). Proc Natl Acad Sci U S A (2007) 1.29
Targeted chromosome elimination from ES-somatic hybrid cells. Nat Methods (2006) 1.20
Induced mitotic recombination of p53 in vivo. Proc Natl Acad Sci U S A (2007) 1.18
New insights into E-protein function in lymphocyte development. Trends Immunol (2005) 1.11
PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res (2007) 1.07
A mitotic recombination system for mouse chromosome 17. Proc Natl Acad Sci U S A (2008) 0.93
Recombination between inverted loxP sites is cytotoxic for proliferating cells and provides a simple tool for conditional cell ablation. Proc Natl Acad Sci U S A (2008) 0.91
Rapid induction of large chromosomal deletions by a Cre/inverted loxP system in mouse ES Cell hybrids. J Mol Biol (2008) 0.80
Target chromosomes of inducible deletion by a Cre/inverted loxP system in mouse embryonic stem cells. Chromosome Res (2009) 0.80
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell (2009) 9.24
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell (2005) 7.29
Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development. Cell (2008) 3.12
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron (2009) 3.10
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell (2007) 3.09
A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. Immunity (2004) 2.30
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development (2007) 2.27
PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling. J Biol Chem (2007) 2.25
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A (2009) 2.07
Double trisomy. Am J Med Genet A (2004) 1.99
Reproductive health services in Malawi: an evaluation of a quality improvement intervention. Midwifery (2011) 1.89
Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol (2012) 1.89
Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3. Nat Immunol (2010) 1.77
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. Genes Dev (2009) 1.76
Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. Immunity (2007) 1.68
Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome. Arthritis Rheum (2008) 1.64
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet (2010) 1.59
Overexpression of PRE1 and its homologous genes activates Gibberellin-dependent responses in Arabidopsis thaliana. Plant Cell Physiol (2006) 1.55
An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. J Immunol (2002) 1.52
A conserved transcriptional enhancer regulates RAG gene expression in developing B cells. Immunity (2003) 1.50
Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis. J Immunol (2009) 1.49
A large-scale functional approach to uncover human genes and pathways in Drosophila. Cell Res (2008) 1.42
Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice. J Immunol (2010) 1.42
ADAM10 is essential for proteolytic activation of Notch during thymocyte development. Int Immunol (2008) 1.38
E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. J Immunol (2007) 1.36
A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol (2009) 1.35
RBPJ mutations identified in two families affected by Adams-Oliver syndrome. Am J Hum Genet (2012) 1.34
Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. FEBS Lett (2010) 1.33
Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells. Microbes Infect (2010) 1.33
Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways. Am J Physiol Heart Circ Physiol (2006) 1.28
E protein transcription factors are required for the development of CD4(+) lineage T cells. Immunity (2012) 1.25
B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice. Immunology (2007) 1.22
E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells. Mol Cell Biol (2006) 1.19
Overexpression of a mutant basic helix-loop-helix protein HFR1, HFR1-deltaN105, activates a branch pathway of light signaling in Arabidopsis. Plant Physiol (2003) 1.18
Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system. Proc Natl Acad Sci U S A (2002) 1.13
Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction. Mol Cell Biol (2002) 1.12
New insights into E-protein function in lymphocyte development. Trends Immunol (2005) 1.11
Increased miR-222 in H. pylori-associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECK. FEBS Lett (2012) 1.10
The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis. Dev Biol (2005) 1.10
Development of the Verona coding definitions of emotional sequences to code health providers' responses (VR-CoDES-P) to patient cues and concerns. Patient Educ Couns (2010) 1.09
Coding patient emotional cues and concerns in medical consultations: the Verona coding definitions of emotional sequences (VR-CoDES). Patient Educ Couns (2010) 1.08
PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res (2007) 1.07
Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer. J Clin Immunol (2012) 1.07
Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response. Curr Biol (2012) 1.05
Modeling Sjögren's syndrome with Id3 conditional knockout mice. Immunol Lett (2011) 1.05
Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian patient. Int J Clin Exp Pathol (2012) 1.04
β4 Integrin signaling induces expansion of prostate tumor progenitors. J Clin Invest (2013) 1.03
Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia. BMC Immunol (2012) 1.01
E2A promotes the survival of precursor and mature B lymphocytes. J Immunol (2006) 1.01
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. J Biol Chem (2005) 1.01
Regulation of E2A activities by histone acetyltransferases in B lymphocyte development. J Biol Chem (2002) 1.00
Chromosome 2q terminal deletion: report of 6 new patients and review of phenotype-breakpoint correlations in 66 individuals. Am J Med Genet A (2004) 1.00
Automated classification of metaphase chromosomes: optimization of an adaptive computerized scheme. J Biomed Inform (2008) 1.00
Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. J Clin Invest (2012) 0.98
Vascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligand. J Biol Chem (2003) 0.98
Automated identification of analyzable metaphase chromosomes depicted on microscopic digital images. J Biomed Inform (2007) 0.97
Application of two bicistronic systems involving 2A and IRES sequences to the biosynthesis of carotenoids in rice endosperm. Plant Biotechnol J (2010) 0.97
Crystal structure of the Gtr1p(GTP)-Gtr2p(GDP) protein complex reveals large structural rearrangements triggered by GTP-to-GDP conversion. J Biol Chem (2012) 0.97
Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines. Mol Cytogenet (2013) 0.97
Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori. Autophagy (2012) 0.96
The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB. Mol Cell Biol (2007) 0.96
Regulation of early lymphocyte development by E2A family proteins. Semin Immunol (2002) 0.95
Maternal serum levels of VCAM-1, ICAM-1 and E-selectin in preeclampsia. J Korean Med Sci (2004) 0.95
A rule-based computer scheme for centromere identification and polarity assignment of metaphase chromosomes. Comput Methods Programs Biomed (2008) 0.94
Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. J Immunol (2014) 0.94
Sex chromosome aneuploidies among men with systemic lupus erythematosus. J Autoimmun (2011) 0.94
Uterine tumor resembling ovarian sex cord tumor: report of a case with t(X;6)(p22.3;q23.1) and t(4;18)(q21.1;q21.3). Diagn Mol Pathol (2003) 0.94
Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion. EMBO J (2007) 0.94
A mitotic recombination system for mouse chromosome 17. Proc Natl Acad Sci U S A (2008) 0.93
Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development. Immunol Res (2011) 0.93
Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response. Mol Cell Proteomics (2009) 0.93
Loss of SDHB and NF1 genes in a malignant phyllodes tumor of the breast as detected by oligo-array comparative genomic hybridization. Cancer Genet Cytogenet (2010) 0.93
Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes. J Biol Chem (2004) 0.92
Measuring the quality of supervisor-provider interactions in health care facilities in Zimbabwe. Int J Qual Health Care (2002) 0.92
Relevance of JAK2V617F positivity to hematological diseases--survey of samples from a clinical genetics laboratory. J Hematol Oncol (2011) 0.92
Study of the effects of total flavonoids of Astragalus on atherosclerosis formation and potential mechanisms. Oxid Med Cell Longev (2012) 0.91
Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes. Autophagy (2013) 0.90
Re-assigned diagnosis of D4ST1-deficient Ehlers-Danlos syndrome (adducted thumb-clubfoot syndrome) after initial diagnosis of Marden-Walker syndrome. Am J Med Genet A (2012) 0.90
MEKK3 is essential for lymphopenia-induced T cell proliferation and survival. J Immunol (2009) 0.89
Adam10 is essential for early embryonic cardiovascular development. Dev Dyn (2010) 0.89
Combined effect of copper, cadmium, and lead upon Cucumis sativus growth and bioaccumulation. Sci Total Environ (2004) 0.89
Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis. Apoptosis (2011) 0.89
Induction of functional cytochrome P450 and its involvement in degradation of benzoic acid by Phanerochaete chrysosporium. Biodegradation (2009) 0.89
Automated detection and analysis of fluorescent in situ hybridization spots depicted in digital microscopic images of Pap-smear specimens. J Biomed Opt (2009) 0.88
Ubiquitous expression of mRFP1 in transgenic mice. Genesis (2005) 0.88
X-chromosome inactivation patterns in Korean women with idiopathic recurrent spontaneous abortion. J Korean Med Sci (2004) 0.88
Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansion. J Immunol (2013) 0.87
Patterns in training, knowledge, and performance of skilled birth attendants providing emergency obstetric and newborn care in Afghanistan. Int J Gynaecol Obstet (2012) 0.87
Klinefelter's syndrome (47,XXY) among men with systemic lupus erythematosus. Acta Paediatr (2011) 0.87
Disruption of lysosome function promotes tumor growth and metastasis in Drosophila. J Biol Chem (2010) 0.87
FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. Transplantation (2002) 0.87
Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts. Wound Repair Regen (2013) 0.87
Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development. Dev Dyn (2010) 0.87
Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis. J Biol Chem (2012) 0.86
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye. BMC Dev Biol (2009) 0.86
A tamoxifen inducible knock-in allele for investigation of E2A function. BMC Dev Biol (2009) 0.86
Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis. J Immunol (2012) 0.86
Male-only systemic lupus. J Rheumatol (2010) 0.86
Leiomyosarcoma of the breast: a pathologic and comparative genomic hybridization study of two cases. Cancer Genet Cytogenet (2004) 0.85
Ring chromosome 9 [r(9)(p24q34)]: a report of two cases. Am J Med Genet A (2005) 0.85