PubRank

Gordon R Bernard

Author PubWeight™ 239.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 2006 19.54
2 Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004 11.27
3 Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008 10.13
4 Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med 2006 7.97
5 Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007 7.74
6 Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). JAMA 2003 6.24
7 Acute lung injury and the acute respiratory distress syndrome: a clinical review. Lancet 2007 6.07
8 Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 2005 5.76
9 Costs associated with delirium in mechanically ventilated patients. Crit Care Med 2004 4.75
10 Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med 2010 4.69
11 Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology 2006 4.03
12 Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome. Crit Care Med 2002 3.87
13 Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med 2005 3.85
14 Principles of human subjects protections applied in an opt-out, de-identified biobank. Clin Transl Sci 2010 3.84
15 A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury. Crit Care Med 2005 3.44
16 Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med 2014 3.39
17 Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med 2003 3.18
18 Attitudes and perceptions of patients towards methods of establishing a DNA biobank. Cell Tissue Bank 2007 3.05
19 Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. Crit Care Med 2010 2.86
20 Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma 2010 2.82
21 Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med 2009 2.77
22 Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients. Crit Care Med 2015 2.77
23 Findings on the portable chest radiograph correlate with fluid balance in critically ill patients. Chest 2002 2.77
24 Large-scale implementation of sedation and delirium monitoring in the intensive care unit: a report from two medical centers. Crit Care Med 2005 2.72
25 A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Crit Care Med 2013 2.68
26 Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury. Crit Care Med 2002 2.62
27 Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS. Chest 2007 2.58
28 Current opinions regarding the importance, diagnosis, and management of delirium in the intensive care unit: a survey of 912 healthcare professionals. Crit Care Med 2004 2.50
29 Sources of variability on the estimate of treatment effect in the PROWESS trial: implications for the design and conduct of future studies in severe sepsis. Crit Care Med 2004 2.48
30 Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med 2003 2.44
31 Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. Crit Care Med 2011 2.40
32 Reengineering the national clinical and translational research enterprise: the strategic plan of the National Clinical and Translational Science Awards Consortium. Acad Med 2010 2.38
33 Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure. Crit Care Med 2011 2.36
34 A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med 2010 2.31
35 Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med 2010 2.28
36 The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit Care Med 2004 2.24
37 Atypical sleep in ventilated patients: empirical electroencephalography findings and the path toward revised ICU sleep scoring criteria. Crit Care Med 2013 2.20
38 Informed consent in research to improve the number and quality of deceased donor organs. Crit Care Med 2011 2.18
39 Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest 2009 2.17
40 Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis. Crit Care Med 2010 2.11
41 Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial. Intensive Care Med 2003 2.05
42 Derivation and validation of Spo2/Fio2 ratio to impute for Pao2/Fio2 ratio in the respiratory component of the Sequential Organ Failure Assessment score. Crit Care Med 2009 2.02
43 Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Crit Care Med 2014 1.98
44 Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury. Crit Care Med 2004 1.88
45 Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia. Crit Care Med 2014 1.84
46 Clinical and translational research studios: a multidisciplinary internal support program. Acad Med 2012 1.78
47 One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med 2014 1.70
48 Long-term cognitive and psychological outcomes in the awakening and breathing controlled trial. Am J Respir Crit Care Med 2010 1.70
49 Randomized trial of automated, electronic monitoring to facilitate early detection of sepsis in the intensive care unit*. Crit Care Med 2012 1.69
50 Consciousness monitoring in ventilated patients: bispectral EEG monitors arousal not delirium. Intensive Care Med 2004 1.68
51 Statins and delirium during critical illness: a multicenter, prospective cohort study. Crit Care Med 2014 1.60
52 Recommendations for informed consent forms for critical care clinical trials. Crit Care Med 2005 1.60
53 An Electronic Tool for the Evaluation and Treatment of Sepsis in the ICU: A Randomized Controlled Trial. Crit Care Med 2015 1.58
54 Drotrecogin alfa (activated) treatment of older patients with severe sepsis. Clin Infect Dis 2003 1.54
55 Risk factors for post-traumatic stress disorder symptoms following critical illness requiring mechanical ventilation: a prospective cohort study. Crit Care 2007 1.53
56 Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma 2010 1.51
57 A replicable method for blood glucose control in critically Ill patients. Crit Care Med 2008 1.50
58 Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome. Ann Intern Med 2002 1.49
59 Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs. Am J Physiol Lung Cell Mol Physiol 2008 1.46
60 A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome. Crit Care Med 2008 1.44
61 Therapeutic intervention and targets for sepsis. Annu Rev Med 2005 1.38
62 Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated). Clin Infect Dis 2003 1.33
63 Evaluation of the effectiveness of posters to provide information to patients about a DNA database and their opportunity to opt out. Cell Tissue Bank 2007 1.31
64 Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest 2015 1.31
65 A placebo-controlled, double-blind, dose-escalation study to assess the safety, tolerability and pharmacokinetics/pharmacodynamics of single and multiple intravenous infusions of AZD9773 in patients with severe sepsis and septic shock. Crit Care 2012 1.31
66 Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. Crit Care 2013 1.26
67 StarBRITE: the Vanderbilt University Biomedical Research Integration, Translation and Education portal. J Biomed Inform 2011 1.26
68 Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome. Crit Care 2006 1.21
69 Activated protein C for severe sepsis. N Engl J Med 2002 1.17
70 Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med 2017 1.15
71 Mechanical ventilation in ARDS: a state-of-the-art review. Chest 2007 1.14
72 Safety and efficacy of affinity-purified, anti-tumor necrosis factor-alpha, ovine fab for injection (CytoFab) in severe sepsis. Crit Care Med 2006 1.11
73 Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med 2015 1.10
74 Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial. Crit Care Med 2015 1.10
75 Association between haptoglobin, hemopexin and mortality in adults with sepsis. Crit Care 2013 1.09
76 The effect of pulmonary artery catheter use on costs and long-term outcomes of acute lung injury. PLoS One 2011 1.03
77 Associations of markers of inflammation and coagulation with delirium during critical illness. Intensive Care Med 2012 1.02
78 Multicenter validation of a computer-based clinical decision support tool for glucose control in adult and pediatric intensive care units. J Diabetes Sci Technol 2008 1.00
79 The role of the coagulation cascade in the continuum of sepsis and acute lung injury and acute respiratory distress syndrome. Semin Respir Crit Care Med 2006 1.00
80 Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial. J Trauma 2011 0.98
81 Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis. Crit Care Med 2015 0.97
82 Clinical Characteristics and Outcomes Are Similar in ARDS Diagnosed by Oxygen Saturation/Fio2 Ratio Compared With Pao2/Fio2 Ratio. Chest 2015 0.97
83 Community Engagement Studios: A Structured Approach to Obtaining Meaningful Input From Stakeholders to Inform Research. Acad Med 2015 0.96
84 PEEP guided by esophageal pressure--any added value? N Engl J Med 2008 0.93
85 Are central institutional review boards the solution? The National Heart, Lung, and Blood Institute Working Group's report on optimizing the IRB process. Acad Med 2012 0.93
86 Proven processes: The Vanderbilt Institute for clinical and translational research . Clin Transl Sci 2009 0.91
87 Vitamin D deficiency and risk of acute lung injury in severe sepsis and severe trauma: a case-control study. Ann Intensive Care 2014 0.90
88 O-glycoside biomarker of apolipoprotein C3: responsiveness to obesity, bariatric surgery, and therapy with metformin, to chronic or severe liver disease and to mortality in severe sepsis and graft vs host disease. J Proteome Res 2009 0.90
89 Longer storage duration of red blood cells is associated with an increased risk of acute lung injury in patients with sepsis. Ann Intensive Care 2013 0.89
90 ARDS Network (NHLBI) studies: successes and challenges in ARDS clinical research. Crit Care Clin 2011 0.86
91 Noninvasive ventilation--don't push too hard. N Engl J Med 2004 0.86
92 Low plasma citrulline levels are associated with acute respiratory distress syndrome in patients with severe sepsis. Crit Care 2013 0.85
93 An informatics-based tool to assist researchers in initiating research at an academic medical center: Vanderbilt Customized Action Plan. Acad Med 2010 0.85
94 Clinical issues and research in respiratory failure from severe acute respiratory syndrome. Am J Respir Crit Care Med 2004 0.83
95 Acute lung injury and the acute respiratory distress syndrome: challenges in clinical trial design. Clin Chest Med 2006 0.82
96 Identifying unpredicted drug benefit through query of patient experiential knowledge: a proof of concept web-based system. Clin Transl Sci 2010 0.80
97 Top-down proteomic analysis by MALDI-TOF profiling: Concentration-independent biomarkers. Proteomics Clin Appl 2008 0.78
98 Steroid treatment for persistent ARDS: a word of caution. Crit Care 2007 0.78
99 Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care 2011 0.78
100 Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial. Ann Intensive Care 2011 0.78
101 Impact of Initial Central Venous Pressure on Outcomes of Conservative Versus Liberal Fluid Management in Acute Respiratory Distress Syndrome. Crit Care Med 2016 0.77
102 The immune response: targets for the treatment of severe sepsis. Int J Inflam 2012 0.77
103 Atypical Sleep in Ventilated Patients: Empirical Electroencephalography Findings and the Path Toward Revised ICU Sleep Scoring Criteria. Crit Care Med 2013 0.76
104 ePrescribing: Reducing Costs through In-Class Therapeutic Interchange. Appl Clin Inform 2016 0.75
105 Drotrecogin alfa (activated) for the treatment of severe sepsis and septic shock. Am J Med Sci 2004 0.75
106 Recommendations to Facilitate Expanded Access to Investigational Therapies for Seriously Ill Patients. Acad Med 2016 0.75
107 Tackling the "so what" problem in scientific research: a systems-based approach to resource and publication tracking. Acad Med 2015 0.75
108 Corticosteroids: the "terminator" of all untreatable serious pulmonary illness. Am J Respir Crit Care Med 2003 0.75
109 New additions to the intensive care armamentarium. Drugs Today (Barc) 2004 0.75
110 CommLog: a communication log system for clinical trials. IEEE Trans Inf Technol Biomed 2003 0.75
111 A case series of drotrecogin alfa (activated) in lung transplant recipients. Transplantation 2006 0.75
112 Identifying personal health experience tweets with deep neural networks. Conf Proc IEEE Eng Med Biol Soc 2017 0.75
113 The Connors et al PAC Study, with expert commentary by Dr Gordon Bernard. J Crit Care 2005 0.75