Published in Hum Mol Genet on June 22, 2010
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Reciprocal interactions of the intestinal microbiota and immune system. Nature (2012) 4.42
The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology (2014) 2.73
Innate lymphoid cells regulate intestinal epithelial cell glycosylation. Science (2014) 2.59
Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype. Proc Natl Acad Sci U S A (2011) 2.47
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet (2011) 2.25
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J Clin Invest (2011) 2.09
Metagenomics and personalized medicine. Cell (2011) 2.00
Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence. Gut (2015) 1.80
Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness. Nature (2014) 1.78
Expression quantitative trait loci analysis identifies associations between genotype and gene expression in human intestine. Gastroenterology (2013) 1.69
Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota. Proc Natl Acad Sci U S A (2013) 1.69
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen. Cell Host Microbe (2014) 1.66
Efficient replication of over 180 genetic associations with self-reported medical data. PLoS One (2011) 1.65
An update on the use and investigation of probiotics in health and disease. Gut (2013) 1.62
Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine. PLoS One (2011) 1.49
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci. J Hepatol (2012) 1.29
Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. ISME J (2014) 1.23
FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection. Diabetes (2011) 1.22
Fucosyltransferase 2 non-secretor and low secretor status predicts severe outcomes in premature infants. J Pediatr (2011) 1.21
Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease. Inflamm Bowel Dis (2013) 1.18
Mucin glycan foraging in the human gut microbiome. Front Genet (2015) 1.14
Faecal microbiota composition in adults is associated with the FUT2 gene determining the secretor status. PLoS One (2014) 1.13
Genetics of Inflammatory Bowel Diseases. Gastroenterology (2015) 1.11
A refined palate: bacterial consumption of host glycans in the gut. Glycobiology (2013) 1.11
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet (2013) 1.04
Intestinal epithelial cells as mediators of the commensal-host immune crosstalk. Immunol Cell Biol (2013) 1.03
The immunogenetic architecture of autoimmune disease. Cold Spring Harb Perspect Biol (2012) 1.00
PUMA: a unified framework for penalized multiple regression analysis of GWAS data. PLoS Comput Biol (2013) 1.00
Presence of multiple independent effects in risk loci of common complex human diseases. Am J Hum Genet (2012) 0.99
Mucin-type O-glycans and their roles in intestinal homeostasis. Glycobiology (2013) 0.98
Role of the microbiota and antibiotics in primary sclerosing cholangitis. Biomed Res Int (2013) 0.97
Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease. J Gastroenterol (2011) 0.97
Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapies. Scand J Gastroenterol (2014) 0.92
Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells. Oncotarget (2015) 0.92
Immune and genetic gardening of the intestinal microbiome. FEBS Lett (2014) 0.91
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links. PLoS Genet (2014) 0.91
Genomics and epigenomics of the human glycome. Glycoconj J (2012) 0.90
Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients. Inflamm Bowel Dis (2014) 0.89
Human milk oligosaccharides and Lewis blood group: individual high-throughput sample profiling to enhance conclusions from functional studies. Adv Nutr (2012) 0.89
Blood Groups in Infection and Host Susceptibility. Clin Microbiol Rev (2015) 0.88
Hepatobiliary manifestations of ulcerative colitis: an example of gut-liver crosstalk. Gastroenterol Rep (Oxf) (2014) 0.87
Genetic Epidemiology of Psoriasis. Curr Dermatol Rep (2014) 0.87
Variants in ZNF365 isoform D are associated with Crohn's disease. Gut (2011) 0.87
Vitamin B-12 status during pregnancy and child's IQ at age 8: a Mendelian randomization study in the Avon longitudinal study of parents and children. PLoS One (2012) 0.86
Glucocorticoids and microbiota regulate ontogeny of intestinal fucosyltransferase 2 requisite for gut homeostasis. Glycobiology (2013) 0.86
Exploring the influence of the gut microbiota and probiotics on health: a symposium report. Br J Nutr (2014) 0.86
Viruses, autophagy genes, and Crohn's disease. Viruses (2011) 0.86
Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection. PLoS Pathog (2015) 0.86
Intestinal Microbiota and Celiac Disease: Cause, Consequence or Co-Evolution? Nutrients (2015) 0.84
Refinement in localization and identification of gene regions associated with Crohn disease. Am J Hum Genet (2012) 0.84
Use of animal models in elucidating disease pathogenesis in IBD. Semin Immunopathol (2014) 0.83
Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway. Inflamm Bowel Dis (2016) 0.83
The causal roles of vitamin B(12) and transcobalamin in prostate cancer: can Mendelian randomization analysis provide definitive answers? Int J Mol Epidemiol Genet (2011) 0.82
Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection. PLoS One (2015) 0.81
Therapeutic approaches for celiac disease. Best Pract Res Clin Gastroenterol (2015) 0.81
Pathogenesis of Crohn's disease. F1000Prime Rep (2015) 0.81
Intestinal fucose as a mediator of host-microbe symbiosis. J Immunol (2015) 0.81
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. Hum Mol Genet (2016) 0.81
Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection. Front Immunol (2015) 0.80
Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation. Am J Hum Genet (2016) 0.80
ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins. BMC Genomics (2016) 0.79
Association of fucosyltransferase 2 gene variants with ulcerative colitis in Han and Uyghur patients in China. World J Gastroenterol (2012) 0.79
Epithelial glycosylation in gut homeostasis and inflammation. Nat Immunol (2016) 0.79
Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci. BMC Genomics (2015) 0.78
Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice. Mucosal Immunol (2016) 0.78
The genetic predisposition and the interplay of host genetics and gut microbiome in Crohn disease. Clin Lab Med (2014) 0.78
The Gut Microbiota and Immune System Relationship in Human Graft-versus-Host Disease. Mediterr J Hematol Infect Dis (2016) 0.78
Estimating the Ages of Selection Signals from Different Epochs in Human History. Mol Biol Evol (2015) 0.77
Isolation of bifidobacteria for blood group secretor status targeted personalised nutrition. Microb Ecol Health Dis (2012) 0.77
Genome-wide association study of susceptibility to infection by Mycobacterium avium subspecies paratuberculosis in Holstein cattle. PLoS One (2014) 0.77
How does knowledge from translational research impact our clinical care of pediatric inflammatory bowel disease patients? Curr Gastroenterol Rep (2012) 0.77
Biological functions of fucose in mammals. Glycobiology (2017) 0.76
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet (2017) 0.76
Association of Ulcerative Colitis with FUT2 and FUT3 Polymorphisms in Patients from Southeast China. PLoS One (2016) 0.76
FUT2 nonfunctional variant: a "missing link" between genes and environment in type 1 diabetes? Diabetes (2011) 0.76
Polymorphisms in PRKCDBP, a Transcriptional Target of TNF-α, Are Associated With Inflammatory Bowel Disease in Korean. Intest Res (2015) 0.76
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits. Nat Genet (2016) 0.76
IL-10-producing CD4(+) T cells negatively regulate fucosylation of epithelial cells in the gut. Sci Rep (2015) 0.76
A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. Hum Mol Genet (2016) 0.76
Mechanisms and consequences of intestinal dysbiosis. Cell Mol Life Sci (2017) 0.76
The microbiota in inflammatory bowel disease: current and therapeutic insights. J Inflamm Res (2017) 0.75
Genetics and Therapeutics in Pediatric Ulcerative Colitis: the Past, Present and Future. F1000Res (2016) 0.75
Association of Fucosyltransferase 2 Gene Polymorphisms with Inflammatory Bowel Disease in Patients from Southeast China. Gastroenterol Res Pract (2017) 0.75
Serum Cytokine Profiles in Children with Crohn's Disease. Mediators Inflamm (2016) 0.75
Multigenerational Influences of the Fut2 Gene on the Dynamics of the Gut Microbiota in Mice. Front Microbiol (2017) 0.75
Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure. Am J Hum Genet (2016) 0.75
eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants. BMC Med Genomics (2016) 0.75
β2→1-Fructans Modulate the Immune System In Vivo in a Microbiota-Dependent and -Independent Fashion. Front Immunol (2017) 0.75
Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese. Oncotarget (2017) 0.75
The role of the innate and adaptive immune system in pediatric inflammatory bowel disease. Inflamm Bowel Dis (2013) 0.75
Genetic Influences on the Development of Fibrosis in Crohn's Disease. Front Med (Lausanne) (2016) 0.75
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Nat Commun (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature (2001) 33.12
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature (2001) 28.24
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
The Cardiovascular Health Study: design and rationale. Ann Epidemiol (1991) 27.24
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2006) 15.14
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature (2009) 9.74
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet (2007) 8.63
A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet (2005) 7.64
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A (2008) 7.43
Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. Am J Hum Genet (1998) 5.82
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35
Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology (2000) 5.34
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J Clin Invest (1996) 4.59
Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology (2004) 4.42
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med (2008) 4.24
Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18
Rational inferences about departures from Hardy-Weinberg equilibrium. Am J Hum Genet (2005) 4.15
Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria. Gastroenterology (2005) 4.10
Characterization of a common susceptibility locus for asthma-related traits. Science (2004) 4.05
Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection. Gastroenterology (1995) 3.44
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med (2007) 3.27
Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens. Gastroenterology (2002) 3.21
Mucins in the mucosal barrier to infection. Mucosal Immunol (2008) 3.17
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. Am J Hum Genet (2008) 3.11
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity. Endocrinology (2009) 3.10
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metab (2008) 2.76
Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur J Immunol (1996) 2.42
The protein disulfide isomerase AGR2 is essential for production of intestinal mucus. Proc Natl Acad Sci U S A (2009) 2.30
Whole-genome genotyping. Methods Enzymol (2006) 2.16
Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet (2008) 2.07
Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet (1986) 2.05
A homozygous nonsense mutation (428G-->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections. J Virol (2005) 1.93
A tail strength measure for assessing the overall univariate significance in a dataset. Biostatistics (2005) 1.90
The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection. PLoS One (2009) 1.89
Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect Immun (1999) 1.85
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum Mol Genet (2004) 1.66
Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm Bowel Dis (2008) 1.57
Influence of the combined ABO, FUT2, and FUT3 polymorphism on susceptibility to Norwalk virus attachment. J Infect Dis (2005) 1.50
The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases. Genes Immun (2007) 1.50
Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats. Gastroenterology (1999) 1.47
Streptococci, ABO blood groups, and secretor status. Am J Hum Genet (1969) 1.46
ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women. Br Med J (Clin Res Ed) (1982) 1.35
MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa. Hum Mol Genet (2008) 1.28
Possible role of blood-group secretory substances in the aetiology of cholera. Trans R Soc Trop Med Hyg (1978) 1.27
Non-secretion of ABO blood group antigens predisposing to infection by Haemophilus influenzae. Lancet (1986) 1.26
Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody. Cancer Epidemiol Biomarkers Prev (2001) 1.21
Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol (2007) 1.20
Non-secretion of blood group antigens and susceptibility to infection by Candida species. FEMS Microbiol Immunol (1989) 1.13
A test for genetic association that incorporates information about deviation from Hardy-Weinberg proportions in cases. Am J Hum Genet (2008) 1.12
A nonsense mutation (428G-->A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection. AIDS (2006) 1.11
A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism. Blood Cells Mol Dis (2002) 1.09
Bacterial symbionts induce a FUT2-dependent fucosylated niche on colonic epithelium via ERK and JNK signaling. Am J Physiol Gastrointest Liver Physiol (2007) 1.08
Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis. Infect Immun (2004) 1.08
MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission. AIDS (2003) 1.04
Chronic atrophic oral candidiasis among patients with diabetes mellitus--role of secretor status. Epidemiol Infect (1991) 1.03
Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes. Biochem J (2004) 1.01
A DNA polymorphism influencing alpha(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion. Immunogenetics (2000) 1.00
Binding specificity of Lactobacillus to glycolipids. Biochem Biophys Res Commun (1996) 0.98
Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice. Lab Invest (2008) 0.95
Characterization of three members of murine alpha1,2-fucosyltransferases: change in the expression of the Se gene in the intestine of mice after administration of microbes. Arch Biochem Biophys (2001) 0.92
Lactobacilli facilitate maintenance of intestinal membrane integrity during Shigella dysenteriae 1 infection in rats. Nutrition (2008) 0.90
Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease. Inflamm Bowel Dis (2008) 0.89
A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels. J Med Genet (2007) 0.88
High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females. Inflamm Bowel Dis (2009) 0.88
Influence of the ABO blood groups and secretor status on bleeding and on perforation of duodenal ulcer. Gut (1968) 0.88
Identification and screening for antimicrobial activity against Clostridium difficile of Bifidobacterium and Lactobacillus species isolated from healthy infant faeces. Int J Antimicrob Agents (2003) 0.86
Polymorphism of the human ABO-Secretor locus (FUT2) in four populations in Asia: indication of distinct Asian subpopulations. Ann Hum Genet (2001) 0.83
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol (2005) 10.16
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet (2011) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest (2004) 5.39
Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science (2012) 5.34
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet (2009) 5.20
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nat Genet (2004) 4.95
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. Gastroenterology (2004) 4.42
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet (2009) 3.82
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat Genet (2009) 3.65
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet (2008) 3.61
Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflamm Bowel Dis (2010) 3.55
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology (2005) 3.41
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens. Gastroenterology (2002) 3.21
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. Am J Hum Genet (2009) 3.19
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet (2009) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
The landscape of recombination in African Americans. Nature (2011) 3.06
Long-range LD can confound genome scans in admixed populations. Am J Hum Genet (2008) 3.06
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Genetic associations with valvular calcification and aortic stenosis. N Engl J Med (2013) 3.02