Published in Circulation on July 06, 2010
Electronic "expression" of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells. Heart Rhythm (2013) 1.75
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia. Blood (2013) 1.73
Induced pluripotent stem cells: developmental biology to regenerative medicine. Nat Rev Cardiol (2010) 1.71
iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes. Circ Cardiovasc Genet (2014) 1.40
Negligible immunogenicity of induced pluripotent stem cells derived from human skin fibroblasts. PLoS One (2014) 1.38
Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.31
microRNAs modulate iPS cell generation. RNA (2011) 1.19
The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells. Biomaterials (2012) 1.16
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem (2013) 1.09
Induced pluripotent stem cells as a disease modeling and drug screening platform. J Cardiovasc Pharmacol (2012) 1.09
Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein. Stem Cell Reports (2015) 1.08
Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. J Physiol (2011) 1.08
Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Res (2011) 1.08
Developing defined culture systems for human pluripotent stem cells. Regen Med (2011) 1.01
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Female sex bias in human embryonic stem cell lines. Stem Cells Dev (2011) 0.99
Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition. Cytotherapy (2011) 0.96
New and TALENted genome engineering toolbox. Circ Res (2013) 0.96
Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation. Cell Death Differ (2012) 0.94
p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGFβ signaling. Cell Death Differ (2015) 0.93
An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity. Cell Death Dis (2012) 0.88
Induced pluripotent stem cells as a next-generation biomedical interface. Lab Invest (2011) 0.87
Gene mutations in cardiac arrhythmias: a review of recent evidence in ion channelopathies. Appl Clin Genet (2013) 0.87
Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells. Circ Cardiovasc Genet (2013) 0.86
N-glycans: phenotypic homology and structural differences between myocardial cells and induced pluripotent stem cell-derived cardiomyocytes. PLoS One (2014) 0.85
From RNAi screens to molecular function in embryonic stem cells. Stem Cell Rev (2012) 0.85
Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines. Circ Cardiovasc Genet (2013) 0.83
Drug discovery models and toxicity testing using embryonic and induced pluripotent stem-cell-derived cardiac and neuronal cells. Stem Cells Int (2012) 0.82
Stem cell therapy for the treatment of parasitic infections: is it far away? Parasitol Res (2013) 0.82
Very small embryonic-like stem cells: biology and therapeutic potential for heart repair. Antioxid Redox Signal (2011) 0.82
Genome-wide mapping of miRNAs expressed in embryonic stem cells and pluripotent stem cells generated by different reprogramming strategies. BMC Genomics (2014) 0.81
Physically associated synthetic hydrogels with long-term covalent stabilization for cell culture and stem cell transplantation. Adv Mater (2011) 0.80
Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectives. Stem Cell Res Ther (2013) 0.80
The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. Stem Cell Rev (2014) 0.80
Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates. Stem Cell Reports (2016) 0.80
Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes. Sci Rep (2016) 0.79
Cell-type-specific predictive network yields novel insights into mouse embryonic stem cell self-renewal and cell fate. PLoS One (2013) 0.79
Dissecting microRNA-mediated regulation of stemness, reprogramming, and pluripotency. Cell Regen (Lond) (2016) 0.78
Recent Stem Cell Advances: Cord Blood and Induced Pluripotent Stem Cell for Cardiac Regeneration- a Review. Int J Stem Cells (2016) 0.77
Human induced pluripotent stem cell for modeling cardiovascular diseases. Regen Med Res (2014) 0.77
Dynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cells. J Allergy Clin Immunol (2014) 0.77
Image-guided therapies for myocardial repair: concepts and practical implementation. Eur Heart J Cardiovasc Imaging (2013) 0.77
Induced pluripotent stem cell technology for dissecting the cancer epigenome. Cancer Sci (2015) 0.77
Grand challenges in the field of stem cell research. Front Cell Dev Biol (2014) 0.76
The role of Wnt regulation in heart development, cardiac repair and disease: A tissue engineering perspective. Biochem Biophys Res Commun (2015) 0.76
hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold. Sci Rep (2015) 0.76
Using induced human pluripotent stem cells to study Diamond-Blackfan anemia: an outlook on the clinical possibilities. Expert Rev Hematol (2013) 0.75
Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by KLF4. Circ Res (2016) 0.75
Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells. J Vis Exp (2016) 0.75
Human induced pluripotent stem cells labeled with fluorescent magnetic nanoparticles for targeted imaging and hyperthermia therapy for gastric cancer. Cancer Biol Med (2015) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72
Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25
Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science (2008) 10.55
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature (2009) 9.75
A more efficient method to generate integration-free human iPS cells. Nat Methods (2011) 7.39
Nanog is the gateway to the pluripotent ground state. Cell (2009) 7.27
Retracted Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science (2004) 7.21
Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc (2007) 7.01
Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol (2009) 6.39
Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell (2009) 4.38
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol (2004) 3.72
Reactivation of the paternal X chromosome in early mouse embryos. Science (2004) 3.59
Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation (2008) 3.11
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature (2003) 3.08
Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell (2009) 3.03
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett (2009) 2.75
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci U S A (2010) 2.52
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells. BMC Dev Biol (2006) 2.50
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins. Mol Cell Biol (2005) 2.47
Promotion of direct reprogramming by transformation-deficient Myc. Proc Natl Acad Sci U S A (2010) 2.44
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol Cell Biol (2003) 2.40
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell (2013) 2.32
Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet (2011) 2.26
An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells (2013) 2.18
iPS cells: a game changer for future medicine. EMBO J (2014) 2.15
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature (2011) 2.11
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Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci U S A (2011) 2.09
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med (2010) 2.08
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci U S A (2009) 2.00
Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One (2011) 1.95
Generation of mouse-induced pluripotent stem cells with plasmid vectors. Nat Protoc (2010) 1.93
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech (2011) 1.87
Steps toward safe cell therapy using induced pluripotent stem cells. Circ Res (2013) 1.80
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.78
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging (Albany NY) (2010) 1.76
Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther (2009) 1.74
Toward the development of a global induced pluripotent stem cell library. Cell Stem Cell (2013) 1.70
New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell (2007) 1.68
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. J Clin Invest (2010) 1.66
Reprogramming somatic cells towards pluripotency by defined factors. Curr Opin Biotechnol (2007) 1.65
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway. J Biol Chem (2005) 1.64
Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J Biol Chem (2004) 1.58
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts. Genes Cells (2009) 1.53
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. Atherosclerosis (2010) 1.52
Generation and characterization of human induced pluripotent stem cells. Curr Protoc Stem Cell Biol (2009) 1.50
Retraction. Science (2007) 1.48
Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate. Stem Cell Reports (2013) 1.48
Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem (2005) 1.46
Magnesium supplementation prevents experimental chronic cyclosporine a nephrotoxicity via renin-angiotensin system independent mechanism. Transplantation (2002) 1.45
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun (2009) 1.45
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun (2009) 1.44
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43
Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report. Arterioscler Thromb Vasc Biol (2009) 1.42
iPS cells: a source of cardiac regeneration. J Mol Cell Cardiol (2010) 1.42
Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells. FASEB J (2010) 1.38
Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation. J Cell Sci (2004) 1.38
Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nat Rev Genet (2009) 1.36
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell (2012) 1.35
Induced pluripotent stem cells in medicine and biology. Development (2013) 1.35
Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells. DNA Res (2008) 1.35
Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells. Genes Cells (2009) 1.35
Intracellular signaling pathways regulating pluripotency of embryonic stem cells. Curr Stem Cell Res Ther (2006) 1.33
Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One (2011) 1.33
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc Natl Acad Sci U S A (2013) 1.32
Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Transl Med (2012) 1.30
Human induced pluripotent stem cells on autologous feeders. PLoS One (2009) 1.28
Generation of human melanocytes from induced pluripotent stem cells. PLoS One (2011) 1.27
Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development. Stem Cells Dev (2012) 1.27
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos Trans R Soc Lond B Biol Sci (2013) 1.26
Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease. PLoS One (2011) 1.23
Immunogenicity of induced pluripotent stem cells. Circ Res (2011) 1.21
Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovasc Res (2010) 1.21
Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicity. PLoS One (2012) 1.20
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis. Cell Res (2011) 1.17
iPS cell technologies: significance and applications to CNS regeneration and disease. Mol Brain (2014) 1.14
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts. Proc Natl Acad Sci U S A (2013) 1.14
Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS One (2011) 1.13
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation. Genes Cells (2006) 1.11
Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture. Circ J (2013) 1.11
Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes. Mol Reprod Dev (2010) 1.11
Induction of pluripotency by defined factors. Exp Cell Res (2010) 1.09
Stem cells assessed. Nat Rev Mol Cell Biol (2012) 1.05
Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells. Stem Cells (2009) 1.04
Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells. Genes Cells (2010) 1.02
Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. Blood (2012) 1.01
Gingival fibroblasts as a promising source of induced pluripotent stem cells. PLoS One (2010) 0.98
To be immunogenic, or not to be: that's the iPSC question. Cell Stem Cell (2013) 0.98
Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2). Genomics (2005) 0.96
Transplantation of mouse induced pluripotent stem cells into the cochlea. Neuroreport (2009) 0.96
Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5). BMC Dev Biol (2006) 0.95
G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. PLoS One (2009) 0.95
Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis (2013) 0.94
Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo. J Invest Dermatol (2013) 0.93