Published in Genetics on July 20, 2010
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Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One (2014) 0.89
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The MAP kinase ERK and its scaffold protein MP1 interact with the chromatin regulator Corto during Drosophila wing tissue development. BMC Dev Biol (2011) 0.83
Piwil2 inhibits keratin 8 degradation through promoting p38-induced phosphorylation to resist Fas-mediated apoptosis. Mol Cell Biol (2014) 0.81
Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb group proteins. Nat Genet (2016) 0.78
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A role for Drosophila Cyclin J in oogenesis revealed by genetic interactions with the piRNA pathway. Mech Dev (2014) 0.75
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A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev (1998) 6.74
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piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development (2000) 4.54
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Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
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Germline stem cell division and egg chamber development in transplanted Drosophila germaria. Dev Biol (1993) 1.66
Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. J Exp Med (2002) 1.62
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The Drosophila Corto protein interacts with Polycomb-group proteins and the GAGA factor. Nucleic Acids Res (2003) 0.96
corto genetically interacts with Pc-G and trx-G genes and maintains the anterior boundary of Ultrabithorax expression in Drosophila larvae. Mol Genet Genomics (2001) 0.95
Mutations in ccf, a novel Drosophila gene encoding a chromosomal factor, affect progression through mitosis and interact with Pc-G mutations. EMBO J (1998) 0.92
Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. Genetics (2003) 0.92
Regulation of Abd-B expression by Cyclin G and Corto in the abdominal epithelium of Drosophila. Hereditas (2008) 0.82
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol (2009) 4.26
An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature (2007) 3.86
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci U S A (2010) 3.28
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MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene (2002) 2.03
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells (2011) 1.90
A major epigenetic programming mechanism guided by piRNAs. Dev Cell (2013) 1.89
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr Biol (2005) 1.88
Nanos maintains germline stem cell self-renewal by preventing differentiation. Science (2004) 1.74
Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad? Mutat Res (2007) 1.63
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat Genet (2010) 1.62
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Precancerous stem cells have the potential for both benign and malignant differentiation. PLoS One (2007) 1.36
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem (2008) 1.32
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. J Biol Chem (2010) 1.30
A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. PLoS Genet (2011) 1.27
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One (2010) 1.17
Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol (2013) 1.16
piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism. Cell Res (2012) 1.15
PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. Development (2011) 1.12
Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res (2010) 1.06
Germline stem cells in the Drosophila ovary descend from pole cells in the anterior region of the embryonic gonad. Development (2004) 1.01
Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity. Proc Natl Acad Sci U S A (2013) 1.00
PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells. Proc Natl Acad Sci U S A (2013) 0.98
High-efficiency siRNA-based gene knockdown in human embryonic stem cells. RNA (2010) 0.98
Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview. Br J Nutr (2008) 0.96
The division of Drosophila germline stem cells and their precursors requires a specific cyclin. Curr Biol (2005) 0.95
Small noncoding RNAs in the germline. Cold Spring Harb Perspect Biol (2011) 0.94
Screens for piwi suppressors in Drosophila identify dosage-dependent regulators of germline stem cell division. Genetics (2003) 0.92
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse. Dev Biol (2011) 0.91
Stem cells: to be and not to be. Nature (2003) 0.89
Repressing the repressor: a lincRNA as a MicroRNA sponge in embryonic stem cell self-renewal. Dev Cell (2013) 0.85
Piwi genes are dispensable for normal hematopoiesis in mice. PLoS One (2013) 0.84
The miRNA Regulation of Stem Cells. Wiley Interdiscip Rev Membr Transp Signal (2011) 0.84
Essential roles of the chromatin remodeling factor BRG1 in spermatogenesis in mice. Biol Reprod (2012) 0.84
Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol (2011) 0.80
Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds. Oncol Rep (2008) 0.80
Sex-lethal is a target of Bruno-mediated translational repression in promoting the differentiation of stem cell progeny during Drosophila oogenesis. Dev Biol (2006) 0.79
High-efficiency transfection and siRNA-mediated gene knockdown in human pluripotent stem cells. Curr Protoc Stem Cell Biol (2012) 0.77
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Poreless eggshells. J Clin Invest (2015) 0.75
Dr. Haifan Lin. Interviewed by Han Lee and Rachel Rosenstein. Yale J Biol Med (2006) 0.75
Stem cells in 2009. Cell Stem Cell (2009) 0.75
Chromatin immunoprecipitation assay of Piwi in Drosophila. Methods Mol Biol (2014) 0.75