Published in Proc Natl Acad Sci U S A on December 23, 2013
Genomic insights into the evolutionary origin of Myxozoa within Cnidaria. Proc Natl Acad Sci U S A (2015) 1.60
Posttranscriptional regulation of gene expression by Piwi proteins and piRNAs. Mol Cell (2014) 0.96
PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression. Natl Sci Rev (2014) 0.92
Piwi Is a Key Regulator of Both Somatic and Germline Stem Cells in the Drosophila Testis. Cell Rep (2015) 0.85
Distinct mechanisms underlie oral vs aboral regeneration in the cnidarian Hydractinia echinata. Elife (2015) 0.85
The ancestral gene repertoire of animal stem cells. Proc Natl Acad Sci U S A (2015) 0.84
A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration. Mol Biol Evol (2015) 0.83
Generation of transgenic Hydra by embryo microinjection. J Vis Exp (2014) 0.82
PIWI homologs mediate histone H4 mRNA localization to planarian chromatoid bodies. Development (2014) 0.82
Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization. RNA (2015) 0.81
Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals. PLoS Genet (2015) 0.79
Stem cells in Nanomia bijuga (Siphonophora), a colonial animal with localized growth zones. Evodevo (2015) 0.77
Germ Line Versus Soma in the Transition from Egg to Embryo. Curr Top Dev Biol (2015) 0.77
A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan. Nat Commun (2016) 0.76
Developmental expression of "germline"- and "sex determination"-related genes in the ctenophore Mnemiopsis leidyi. Evodevo (2016) 0.76
Hydra as a tractable, long-lived model system for senescence. Invertebr Reprod Dev (2014) 0.76
The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review). Int J Oncol (2015) 0.75
Multi-functionality and plasticity characterize epithelial cells in Hydra. Tissue Barriers (2015) 0.75
Vertically- and horizontally-transmitted memories - the fading boundaries between regeneration and inheritance in planaria. Biol Open (2016) 0.75
Epigenetics and Shared Molecular Processes in the Regeneration of Complex Structures. Stem Cells Int (2015) 0.75
Profiling of adhesive-related genes in the freshwater cnidarian Hydra magnipapillata by transcriptomics and proteomics. Biofouling (2016) 0.75
A microRNA-mRNA expression network during oral siphon regeneration in Ciona. Development (2017) 0.75
Abundant expression of somatic transposon-derived piRNAs throughout Tribolium castaneum embryogenesis. Genome Biol (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
Developmentally regulated piRNA clusters implicate MILI in transposon control. Science (2007) 7.68
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature (2008) 6.81
A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev (1998) 6.74
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell (2008) 6.35
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol (2011) 5.59
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends. Genes Dev (2007) 4.68
piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development (2000) 4.54
The dynamic genome of Hydra. Nature (2010) 4.00
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
The role of PIWI and the miRNA machinery in Drosophila germline determination. Curr Biol (2006) 3.06
Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell (2012) 3.04
The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated. Nat Struct Mol Biol (2007) 2.71
A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol (2009) 2.69
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Transgenic Hydra allow in vivo tracking of individual stem cells during morphogenesis. Proc Natl Acad Sci U S A (2006) 2.00
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Mass culture of hydra: an improved method and its application to other aquatic invertebrates. Lab Anim (1970) 1.91
A major epigenetic programming mechanism guided by piRNAs. Dev Cell (2013) 1.89
Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J (2008) 1.87
Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Blood (2001) 1.74
Developmental biology. Versatile germline genes. Science (2010) 1.46
Pattern of epithelial cell cycling in hydra. Dev Biol (1991) 1.23
Molecular signatures of the three stem cell lineages in hydra and the emergence of stem cell function at the base of multicellularity. Mol Biol Evol (2012) 1.20
Characterization of interstitial stem cells in hydra by cloning. Dev Biol (1977) 1.18
Agalma: an automated phylogenomics workflow. BMC Bioinformatics (2013) 1.11
Evolution of the bilaterian germ line: lineage origin and modulation of specification mechanisms. Integr Comp Biol (2007) 1.11
Somatic stem cells express Piwi and Vasa genes in an adult ctenophore: ancient association of "germline genes" with stemness. Dev Biol (2010) 1.10
The germ line and somatic stem cell gene Cniwi in the jellyfish Podocoryne carnea. Int J Dev Biol (2004) 1.07
Untangling the web: the diverse functions of the PIWI/piRNA pathway. Mol Reprod Dev (2013) 0.98
Two different evolutionary origins of stem cell systems and their molecular basis. Semin Cell Dev Biol (2006) 0.97
Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata. Nucleic Acids Res (2012) 0.94
Expression of the Argonaute protein PiwiL2 and piRNAs in adult mouse mesenchymal stem cells. Biochem Biophys Res Commun (2010) 0.88
Incorporation of a horizontally transferred gene into an operon during cnidarian evolution. PLoS One (2012) 0.86
A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra. Development (2013) 0.84
Interstitial stem cells in Hydra: multipotency and decision-making. Int J Dev Biol (2012) 0.83
Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway. Dev Biol (2013) 0.82
Genetic analysis of developmental mechanisms in hydra. XVIII. Mechanism for elimination of the interstitial cell lineage in the mutant strain Sf-1. Dev Biol (1988) 0.81
Interstitial stem cell proliferation in hydra: evidence for strain-specific regulatory signals. Dev Biol (1991) 0.77
Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization. Science (2007) 9.79
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell (2009) 5.49
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function. Proc Natl Acad Sci U S A (2009) 4.29
MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol (2009) 4.26
[Smoking and passive smoking in Chinese, 2002]. Zhonghua Liu Xing Bing Xue Za Zhi (2005) 4.19
The dynamic genome of Hydra. Nature (2010) 4.00
An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature (2007) 3.86
Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A (2004) 3.58
Clinical application of massively parallel sequencing-based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11,105 pregnancies with mixed risk factors. Prenat Diagn (2012) 3.54
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol (2008) 3.40
Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci U S A (2010) 3.28
The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol (2009) 3.21
The role of PIWI and the miRNA machinery in Drosophila germline determination. Curr Biol (2006) 3.06
Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell (2009) 3.02
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet (2010) 2.84
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome Res (2010) 2.30
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Generation of induced pluripotent stem cell lines from Tibetan miniature pig. J Biol Chem (2009) 2.17
Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol (2009) 2.13
Association of leptin with mortality in patients on maintenance hemodialysis: a prospective study. Iran J Kidney Dis (2014) 2.09
Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet (2011) 2.07
Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene (2002) 2.03
The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes. Genes Dev (2008) 1.95
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Evolutionary differences in glycosaminoglycan fine structure detected by quantitative glycan reductive isotope labeling. J Biol Chem (2008) 1.91
Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells. Stem Cells (2011) 1.90
A major epigenetic programming mechanism guided by piRNAs. Dev Cell (2013) 1.89
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr Biol (2005) 1.88
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. Curr Biol (2010) 1.84
Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression. Mol Cell (2012) 1.76
Nanos maintains germline stem cell self-renewal by preventing differentiation. Science (2004) 1.74
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
Drosophila Piwi functions in Hsp90-mediated suppression of phenotypic variation. Nat Genet (2010) 1.62
Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J Clin Invest (2005) 1.61
Human bocavirus in children hospitalized for acute gastroenteritis: a case-control study. Clin Infect Dis (2008) 1.61
Dicing of viral replication intermediates during silencing of latent Drosophila viruses. Proc Natl Acad Sci U S A (2009) 1.61
A photoactivatable push-pull fluorophore for single-molecule imaging in live cells. J Am Chem Soc (2008) 1.60
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57
RNA editing in regulating gene expression in the brain. Biochim Biophys Acta (2007) 1.54
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Reversal of multidrug resistance of gastric cancer cells by downregulation of TSG101 with TSG101siRNA. Cancer Biol Ther (2004) 1.51
Identification and nearly full-length genome characterization of novel porcine bocaviruses. PLoS One (2010) 1.51
Evolutionary crossroads in developmental biology: Cnidaria. Development (2011) 1.46
Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein. Cancer Biol Ther (2004) 1.44
Germ line determinants are not localized early in sea urchin development, but do accumulate in the small micromere lineage. Dev Biol (2006) 1.43
Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila. Nat Struct Mol Biol (2013) 1.42
A conserved germline multipotency program. Development (2010) 1.42
Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells. J Biol Chem (2010) 1.41
Candidate porcine Kobuvirus, China. Emerg Infect Dis (2009) 1.40
A Morphometric Study of the Newborn Ear and an Analysis of Factors Related to Congenital Auricular Deformities. Plast Reconstr Surg (2017) 1.40
Tuning of RNA editing by ADAR is required in Drosophila. EMBO J (2005) 1.39
Transition from isolated to collective modes in plasmonic oligomers. Nano Lett (2010) 1.39
The ADAR protein family. Genome Biol (2012) 1.39
Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nat Neurosci (2011) 1.36
Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol (2010) 1.36
Precancerous stem cells have the potential for both benign and malignant differentiation. PLoS One (2007) 1.36
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
Engineered alterations in RNA editing modulate complex behavior in Drosophila: regulatory diversity of adenosine deaminase acting on RNA (ADAR) targets. J Biol Chem (2010) 1.34
Small micromeres contribute to the germline in the sea urchin. Development (2011) 1.33
Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem (2008) 1.32
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. J Biol Chem (2010) 1.30
The oxidative burst at fertilization is dependent upon activation of the dual oxidase Udx1. Dev Cell (2004) 1.29
Nanos functions to maintain the fate of the small micromere lineage in the sea urchin embryo. Dev Biol (2009) 1.29
Defending the zygote: search for the ancestral animal block to polyspermy. Curr Top Dev Biol (2006) 1.28
Enantioselective bromolactonization of conjugated (Z)-enynes. J Am Chem Soc (2010) 1.27
NDRG2 expression and mutation in human liver and pancreatic cancers. World J Gastroenterol (2004) 1.27
The repression of human differentiation-related gene NDRG2 expression by Myc via Miz-1-dependent interaction with the NDRG2 core promoter. J Biol Chem (2006) 1.27
A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. PLoS Genet (2011) 1.27
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
Membrane hemifusion is a stable intermediate of exocytosis. Dev Cell (2007) 1.26
Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol (2007) 1.25
NDRG2 is a new HIF-1 target gene necessary for hypoxia-induced apoptosis in A549 cells. Cell Physiol Biochem (2008) 1.24
Cellular prion protein promotes invasion and metastasis of gastric cancer. FASEB J (2006) 1.23
Vasa genes: emerging roles in the germ line and in multipotent cells. Bioessays (2010) 1.23
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res (2011) 1.22
Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. Thromb Res (2007) 1.20
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Hospital-Based Surveillance of Rotavirus Diarrhea in the People's Republic of China, August 2003-July 2007. J Infect Dis (2009) 1.19
Viral agents associated with acute gastroenteritis in children hospitalized with diarrhea in Lanzhou, China. J Clin Virol (2009) 1.18
Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells. Cell Res (2011) 1.18
Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One (2010) 1.17
Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR. Int J Cancer (2005) 1.16
Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol (2013) 1.16
Arginine methylation of hnRNP K enhances p53 transcriptional activity. FEBS Lett (2008) 1.15
piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism. Cell Res (2012) 1.15
Permanent Genetic Resources added to Molecular Ecology Resources Database 1 May 2009-31 July 2009. Mol Ecol Resour (2009) 1.15
Role of epidermal growth factor receptor in acute and chronic kidney injury. Kidney Int (2013) 1.14