Published in Nat Rev Mol Cell Biol on September 01, 2010
Mitochondria: in sickness and in health. Cell (2012) 6.05
Making heads or tails of phospholipids in mitochondria. J Cell Biol (2011) 2.55
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell (2012) 2.52
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration. Nat Cell Biol (2012) 2.25
Mitochondrial form and function. Nature (2014) 2.11
Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation. Nat Rev Mol Cell Biol (2011) 1.91
Mitochondrial quality control: a matter of life and death for neurons. EMBO J (2012) 1.83
Pharmacological approaches to restore mitochondrial function. Nat Rev Drug Discov (2013) 1.66
Modulating molecular chaperones improves sensory fiber recovery and mitochondrial function in diabetic peripheral neuropathy. Exp Neurol (2012) 1.59
The therapeutic potential of mitochondrial channels in cancer, ischemia-reperfusion injury, and neurodegeneration. Mitochondrion (2011) 1.48
Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond. Trends Cell Biol (2013) 1.42
Pre-microRNA and mature microRNA in human mitochondria. PLoS One (2011) 1.29
SOD1 and mitochondria in ALS: a dangerous liaison. J Bioenerg Biomembr (2011) 1.24
Trafficking of protein into the recently established photosynthetic organelles of Paulinella chromatophora. Proc Natl Acad Sci U S A (2012) 1.20
New insights into the mechanism of chloroplast protein import and its integration with protein quality control, organelle biogenesis and development. J Mol Biol (2014) 1.19
Skeletal muscle proteomics: current approaches, technical challenges and emerging techniques. Skelet Muscle (2011) 1.18
Mitochondrial protein synthesis, import, and assembly. Genetics (2012) 1.17
Mitochondrial membrane lipidome defines yeast longevity. Aging (Albany NY) (2013) 1.14
Intermembrane space proteome of yeast mitochondria. Mol Cell Proteomics (2012) 1.09
FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy. Hum Mol Genet (2010) 1.08
Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts. J Cell Biol (2015) 1.07
Mitochondrial outer membrane proteome of Trypanosoma brucei reveals novel factors required to maintain mitochondrial morphology. Mol Cell Proteomics (2012) 1.03
The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol (2011) 1.03
Mitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heart. Cell Metab (2015) 1.02
PNPASE and RNA trafficking into mitochondria. Biochim Biophys Acta (2011) 1.01
MitoFates: improved prediction of mitochondrial targeting sequences and their cleavage sites. Mol Cell Proteomics (2015) 1.00
Diabetic retinopathy and damage to mitochondrial structure and transport machinery. Invest Ophthalmol Vis Sci (2011) 1.00
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation. Cell Metab (2013) 1.00
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. Aging Cell (2012) 0.99
Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach? Pharmacol Rev (2012) 0.99
Direct induction of apoptosis using an optimal mitochondrially targeted p53. Mol Pharm (2012) 0.98
Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell (2011) 0.97
Dual location of the mitochondrial preprotein transporters B14.7 and Tim23-2 in complex I and the TIM17:23 complex in Arabidopsis links mitochondrial activity and biogenesis. Plant Cell (2012) 0.97
C-terminal heat shock protein 90 inhibitor decreases hyperglycemia-induced oxidative stress and improves mitochondrial bioenergetics in sensory neurons. J Proteome Res (2012) 0.96
Selective sorting and destruction of mitochondrial membrane proteins in aged yeast. Elife (2016) 0.96
The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins. Mol Cell Biol (2013) 0.95
Systematic analysis of small RNAs associated with human mitochondria by deep sequencing: detailed analysis of mitochondrial associated miRNA. PLoS One (2012) 0.95
The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. Nat Med (2016) 0.94
Mitochondrial biogenesis through activation of nuclear signaling proteins. Cold Spring Harb Perspect Biol (2013) 0.94
Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates. Cell Mol Life Sci (2012) 0.93
HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion. Cell Death Dis (2012) 0.93
Application of a proapoptotic peptide to intratumorally spreading cancer therapy. Cancer Res (2012) 0.93
Selective escape of proteins from the mitochondria during mitophagy. Nat Commun (2013) 0.93
Differential age-dependent import regulation by signal peptides. PLoS Biol (2012) 0.92
Structure and function of mitochondrial membrane protein complexes. BMC Biol (2015) 0.91
Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis. Cell Rep (2013) 0.91
An essential novel component of the noncanonical mitochondrial outer membrane protein import system of trypanosomatids. Mol Biol Cell (2012) 0.90
Dynamic survey of mitochondria by ubiquitin. EMBO Rep (2014) 0.90
Cytosolic thioredoxin system facilitates the import of mitochondrial small Tim proteins. EMBO Rep (2012) 0.90
Specific targeting of proteins to outer envelope membranes of endosymbiotic organelles, chloroplasts, and mitochondria. Front Plant Sci (2014) 0.89
Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory phenomenon. Exp Eye Res (2014) 0.89
Retro-translocation of mitochondrial intermembrane space proteins. Proc Natl Acad Sci U S A (2015) 0.88
TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex. Mol Cell Biol (2013) 0.88
Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors. Angew Chem Int Ed Engl (2012) 0.88
The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging. J Parkinsons Dis Alzheimers Dis (2014) 0.88
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress. Autophagy (2012) 0.87
Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy. J Pharmacol Exp Ther (2013) 0.87
Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae. J Biol Chem (2011) 0.87
Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol (2011) 0.87
Direct interaction of mitochondrial targeting presequences with purified components of the TIM23 protein complex. J Biol Chem (2011) 0.87
Mitochondrial protein import receptors in Kinetoplastids reveal convergent evolution over large phylogenetic distances. Nat Commun (2015) 0.86
LETM proteins play a role in the accumulation of mitochondrially encoded proteins in Arabidopsis thaliana and AtLETM2 displays parent of origin effects. J Biol Chem (2012) 0.86
Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex. Mol Biol Cell (2011) 0.86
Intramolecular disulfide bond of Tim22 protein maintains integrity of the TIM22 complex in the mitochondrial inner membrane. J Biol Chem (2014) 0.86
Genome evolution in the cold: Antarctic icefish muscle transcriptome reveals selective duplications increasing mitochondrial function. Genome Biol Evol (2013) 0.86
Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease. Hum Mol Genet (2012) 0.85
Viruses as modulators of mitochondrial functions. Adv Virol (2013) 0.85
Protein translocase of mitochondrial inner membrane in Trypanosoma brucei. J Biol Chem (2012) 0.85
The mitochondrial unfolded protein response in mammalian physiology. Mamm Genome (2014) 0.84
Impaired transport of mitochondrial transcription factor A (TFAM) and the metabolic memory phenomenon associated with the progression of diabetic retinopathy. Diabetes Metab Res Rev (2013) 0.84
The Neurospora crassa TOB complex: analysis of the topology and function of Tob38 and Tob37. PLoS One (2011) 0.84
Emerging concepts in the flavinylation of succinate dehydrogenase. Biochim Biophys Acta (2013) 0.84
Visualizing active membrane protein complexes by electron cryotomography. Nat Commun (2014) 0.84
Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites. PLoS Pathog (2014) 0.84
Role of membrane contact sites in protein import into mitochondria. Protein Sci (2015) 0.84
Architecture of the TIM23 inner mitochondrial translocon and interactions with the matrix import motor. J Biol Chem (2014) 0.84
Tom70 is essential for PINK1 import into mitochondria. PLoS One (2013) 0.84
Genetic analysis of complex interactions among components of the mitochondrial import motor and translocon in Saccharomyces cerevisiae. Genetics (2012) 0.83
Regulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effect. Biochim Biophys Acta (2011) 0.83
Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. Sci Rep (2015) 0.83
Tim50 in Trypanosoma brucei possesses a dual specificity phosphatase activity and is critical for mitochondrial protein import. J Biol Chem (2012) 0.83
Borrowing nuclear DNA helicases to protect mitochondrial DNA. Int J Mol Sci (2015) 0.82
Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase. Mol Cell Biol (2013) 0.82
Localized translation near the mitochondrial outer membrane: An update. RNA Biol (2015) 0.82
The cell-free integration of a polytopic mitochondrial membrane protein into liposomes occurs cotranslationally and in a lipid-dependent manner. PLoS One (2012) 0.82
An engineered dimeric protein pore that spans adjacent lipid bilayers. Nat Commun (2013) 0.82
The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res (2016) 0.82
Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids. J Bioenerg Biomembr (2016) 0.82
Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy. Cell Res (2014) 0.81
A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria. Mol Biol Cell (2014) 0.81
Recent advances in the composition and heterogeneity of the Arabidopsis mitochondrial proteome. Front Plant Sci (2013) 0.81
Dictyostelium dynamin B modulates cytoskeletal structures and membranous organelles. Cell Mol Life Sci (2010) 0.81
Cardiomyocyte specific deletion of Crif1 causes mitochondrial cardiomyopathy in mice. PLoS One (2013) 0.81
The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1. J Cell Biol (2015) 0.80
Role of the import motor in insertion of transmembrane segments by the mitochondrial TIM23 complex. EMBO Rep (2011) 0.80
The Role of Mitochondrial Functional Proteins in ROS Production in Ischemic Heart Diseases. Oxid Med Cell Longev (2016) 0.79
Rational design of crystal contact-free space in protein crystals for analyzing spatial distribution of motions within protein molecules. Protein Sci (2016) 0.79
Topological probes of monoamine oxidases A and B in rat liver mitochondria: inhibition by TEMPO-substituted pargyline analogues and inactivation by proteolysis. Biochemistry (2011) 0.79
Protein import into the photosynthetic organelles of Paulinella chromatophora and its implications for primary plastid endosymbiosis. Symbiosis (2012) 0.79
Post-zygotic sterility and cytonuclear compatibility limits in S. cerevisiae xenomitochondrial cybrids. Front Genet (2015) 0.79
A mitochondrial protein compendium elucidates complex I disease biology. Cell (2008) 13.51
Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature (2008) 9.66
Blue native PAGE. Nat Protoc (2006) 8.04
Translocation of proteins into mitochondria. Annu Rev Biochem (2007) 7.53
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell (2003) 6.77
An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science (2009) 6.14
Characterization of the human heart mitochondrial proteome. Nat Biotechnol (2003) 5.66
Importing mitochondrial proteins: machineries and mechanisms. Cell (2009) 5.46
Exploration of essential gene functions via titratable promoter alleles. Cell (2004) 5.21
The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A (2003) 5.13
Function and biogenesis of iron-sulphur proteins. Nature (2009) 4.56
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70. Cell (2003) 4.46
A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell (2005) 4.41
Phospholipid synthesis in a membrane fraction associated with mitochondria. J Biol Chem (1990) 4.22
Cytoplasmic type 80S ribosomes associated with yeast mitochondria. IV. Attachment of ribosomes to the outer membrane of isolated mitochondria. J Cell Biol (1975) 3.82
The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell (2005) 3.72
Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane. J Cell Biol (1994) 3.53
Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature (2003) 3.46
Expanded protein information at SGD: new pages and proteome browser. Nucleic Acids Res (2006) 3.31
The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria. J Cell Biol (2003) 3.11
New developments in mitochondrial assembly. Annu Rev Cell Dev Biol (2004) 3.07
A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23. Nat Struct Biol (2001) 3.06
Evolution of the molecular machines for protein import into mitochondria. Science (2006) 3.03
Evolutionary conservation of biogenesis of beta-barrel membrane proteins. Nature (2003) 2.98
Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell (2008) 2.97
Genome-wide analysis of mRNAs targeted to yeast mitochondria. EMBO Rep (2002) 2.94
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res (2006) 2.92
The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies. Trends Cell Biol (2007) 2.64
An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem (2003) 2.59
Quantitative proteomic comparison of rat mitochondria from muscle, heart, and liver. Mol Cell Proteomics (2006) 2.57
Mitochondrial processing peptidases. Biochim Biophys Acta (2002) 2.53
Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell (2005) 2.49
Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller. Mol Cell (2006) 2.46
Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J (2004) 2.43
Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor. J Cell Biol (2004) 2.36
Integrative analysis of the mitochondrial proteome in yeast. PLoS Biol (2004) 2.31
Proteomic approach to identify novel mitochondrial proteins in Arabidopsis. Plant Physiol (2001) 2.23
Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases. Crit Rev Biochem Mol Biol (2007) 2.18
A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery. Mol Biol Cell (2003) 2.14
The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell (2004) 1.98
Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell (2009) 1.96
The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell (2002) 1.95
Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science (2003) 1.89
The pathophysiology of mitochondrial disease as modeled in the mouse. Genes Dev (2009) 1.87
Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins. EMBO J (2006) 1.83
Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell (2002) 1.82
Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure (2001) 1.81
A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. J Mol Biol (2002) 1.80
Profiling constitutive proteolytic events in vivo. Biochem J (2007) 1.78
Erv1 mediates the Mia40-dependent protein import pathway and provides a functional link to the respiratory chain by shuttling electrons to cytochrome c. J Mol Biol (2005) 1.76
Systematic analysis of the twin cx(9)c protein family. J Mol Biol (2009) 1.75
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell (2006) 1.75
The TOM core complex: the general protein import pore of the outer membrane of mitochondria. J Cell Biol (1999) 1.73
Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space. J Biol Chem (2004) 1.69
Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol (2004) 1.67
The disulfide relay system of mitochondria is connected to the respiratory chain. J Cell Biol (2007) 1.66
Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol (2007) 1.64
Mitochondrial protein-import machinery: correlating structure with function. Trends Cell Biol (2007) 1.64
Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol (2004) 1.63
Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol (2009) 1.62
The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Nat Struct Mol Biol (2004) 1.61
The Tim8-Tim13 complex of Neurospora crassa functions in the assembly of proteins into both mitochondrial membranes. J Biol Chem (2004) 1.61
The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria. EMBO J (2001) 1.60
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria. Nat Struct Mol Biol (2009) 1.60
Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett (2005) 1.59
The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J (2007) 1.58
Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway. J Biol Chem (2004) 1.55
The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. EMBO J (2002) 1.55
Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science (2006) 1.55
Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway. J Mol Biol (2006) 1.53
Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol (2009) 1.42
A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1. EMBO J (2007) 1.41
Identification of the signal directing Tim9 and Tim10 into the intermembrane space of mitochondria. Mol Biol Cell (2009) 1.41
The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins. J Mol Biol (2005) 1.40
Signals in bacterial beta-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria. Proc Natl Acad Sci U S A (2009) 1.40
Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione. Mol Cell (2010) 1.38
Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J Cell Biol (2007) 1.36
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol (2005) 1.34
Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J (2008) 1.34
The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem (2004) 1.34
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics (2007) 1.33
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol (2008) 1.32
A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol (2006) 1.32
Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex. Hum Mol Genet (2002) 1.31
Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states. EMBO J (2007) 1.31
Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria. J Cell Biol (2006) 1.30
Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase. J Cell Biol (2008) 1.28
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Mol Cell Proteomics (2007) 1.27
Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase. Mol Biol Cell (2006) 1.26
Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem (2005) 1.26
A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding. J Cell Biol (2009) 1.26
Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components. J Cell Sci (2008) 1.26
Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10. J Biol Chem (2006) 1.24
Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J (2006) 1.24
Systematic identification of mitochondrial proteins by LC-MS/MS. Anal Chem (2002) 1.24
Tom20 mediates localization of mRNAs to mitochondria in a translation-dependent manner. Mol Cell Biol (2010) 1.23
The mitochondrial proteome: from inventory to function. Cell (2008) 1.23
Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins. J Cell Biol (2007) 1.22
The N-end rule at atomic resolution. Nat Struct Mol Biol (2008) 1.21
Importing mitochondrial proteins: machineries and mechanisms. Cell (2009) 5.46
The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A (2003) 5.13
Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature (2003) 3.46
Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell (2008) 2.97
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res (2006) 2.92
Mitochondrial import and the twin-pore translocase. Nat Rev Mol Cell Biol (2004) 2.78
An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem (2003) 2.59
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell (2011) 2.52
Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell (2005) 2.49
Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J (2004) 2.43
Multiple pathways for sorting mitochondrial precursor proteins. EMBO Rep (2008) 2.19
Isolation of yeast mitochondria. Methods Mol Biol (2006) 2.09
The protein import machinery of mitochondria. J Biol Chem (2004) 2.02
Assembling the mitochondrial outer membrane. Nat Struct Mol Biol (2004) 2.00
Mitochondrial preprotein translocase of trypanosomatids has a bacterial origin. Curr Biol (2011) 1.98
The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell (2004) 1.98
Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell (2009) 1.96
The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell (2002) 1.95
Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J (2005) 1.92
Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science (2003) 1.89
Mechanisms of protein import into mitochondria. Curr Biol (2003) 1.76
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell (2006) 1.75
A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol (2003) 1.71
Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol (2007) 1.64
Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol (2004) 1.63
Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol (2009) 1.62
Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains. J Mol Biol (2012) 1.61
The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J (2007) 1.58
Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway. J Biol Chem (2004) 1.55
Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. Mol Biol Cell (2005) 1.55
Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science (2006) 1.55
Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway. J Mol Biol (2006) 1.53
Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metab (2012) 1.48
Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour. J Mol Biol (2003) 1.43
A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J (2011) 1.42
Regulation of mitochondrial protein import by cytosolic kinases. Cell (2011) 1.42
The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins. J Mol Biol (2005) 1.40
Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem (2004) 1.37
Role of MINOS in mitochondrial membrane architecture and biogenesis. Trends Cell Biol (2012) 1.36
Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J Cell Biol (2007) 1.36
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol (2005) 1.34
Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol (2014) 1.34
The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem (2004) 1.34
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics (2007) 1.33
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol (2008) 1.32
A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol (2006) 1.32
Import of proteins into mitochondria. Methods Cell Biol (2007) 1.30
Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase. J Cell Biol (2008) 1.28
Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40. J Biol Chem (2007) 1.27
Cooperation of translocase complexes in mitochondrial protein import. J Cell Biol (2007) 1.26
Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10. J Biol Chem (2006) 1.24
Mitochondrial protein import: from transport pathways to an integrated network. Trends Biochem Sci (2011) 1.23
The mitochondrial proteome: from inventory to function. Cell (2008) 1.23
Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins. J Cell Biol (2007) 1.22
Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space. Mol Biol Cell (2007) 1.22
Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J (2003) 1.21
Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex. Mol Cell Biol (2002) 1.19
Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol (2005) 1.16
Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem (2007) 1.15
Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol (2003) 1.14
Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane. Mol Cell (2011) 1.14
Protein translocase of the outer mitochondrial membrane: role of import receptors in the structural organization of the TOM complex. J Mol Biol (2002) 1.12
Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol (2010) 1.11
Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell (2013) 1.11
Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel. Mol Cell (2002) 1.11
A dynamic machinery for import of mitochondrial precursor proteins. FEBS Lett (2007) 1.10
Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes. J Mol Biol (2012) 1.10
Intermembrane space proteome of yeast mitochondria. Mol Cell Proteomics (2012) 1.09
Processing of mitochondrial presequences. Biochim Biophys Acta (2011) 1.06
Mitofilin complexes: conserved organizers of mitochondrial membrane architecture. Biol Chem (2012) 1.06
Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex. Mol Cell Biol (2003) 1.05