PubRank

John N Wood

Author PubWeight™ 121.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An SCN9A channelopathy causes congenital inability to experience pain. Nature 2006 7.01
2 SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 2006 3.96
3 The cell and molecular basis of mechanical, cold, and inflammatory pain. Science 2008 3.46
4 A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. Neuron 2010 3.31
5 Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci U S A 2004 3.07
6 Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron 2005 3.03
7 Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures. Nature 2007 2.71
8 The TTX-resistant sodium channel Nav1.8 (SNS/PN3): expression and correlation with membrane properties in rat nociceptive primary afferent neurons. J Physiol 2003 2.59
9 Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones. J Physiol 2004 2.48
10 Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons. J Neurosci 2002 2.40
11 Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain 2012 2.34
12 Loss-of-function mutations in sodium channel Nav1.7 cause anosmia. Nature 2011 2.31
13 Genetic variation in SCN10A influences cardiac conduction. Nat Genet 2010 2.30
14 The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci 2012 2.28
15 VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron 2010 2.22
16 Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia. Pain 2011 1.90
17 Annexin II light chain regulates sensory neuron-specific sodium channel expression. Nature 2002 1.88
18 Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8. Mol Pain 2005 1.86
19 Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nat Commun 2012 1.72
20 Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice. Pain 2005 1.72
21 Remote optogenetic activation and sensitization of pain pathways in freely moving mice. J Neurosci 2013 1.62
22 GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones. J Physiol 2003 1.62
23 Neurological perspectives on voltage-gated sodium channels. Brain 2012 1.62
24 The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice. J Physiol 2003 1.54
25 Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron 2008 1.52
26 GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9. J Physiol 2007 1.49
27 Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice. J Neurosci 2002 1.48
28 High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One 2007 1.38
29 Modulation of sensory neuron mechanotransduction by PKC- and nerve growth factor-dependent pathways. Proc Natl Acad Sci U S A 2006 1.38
30 Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis. Proc Natl Acad Sci U S A 2013 1.34
31 Pain as a channelopathy. J Clin Invest 2010 1.33
32 Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds. J Neurosci 2010 1.28
33 Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain. Mol Cell Neurosci 2006 1.24
34 The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain. Pain Med 2011 1.23
35 Pain genes. PLoS Genet 2008 1.23
36 Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain 2006 1.21
37 Increasingly irritable and close to tears: TRPA1 in inflammatory pain. Cell 2006 1.18
38 Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. J Comp Neurol 2011 1.16
39 TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biol 2012 1.16
40 GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain. J Neurosci 2010 1.15
41 Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling. EMBO J 2012 1.15
42 FM1-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli. Mol Pain 2007 1.12
43 Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior. J Neurosci 2006 1.11
44 Kinetic properties of mechanically activated currents in spinal sensory neurons. J Physiol 2009 1.10
45 Pain channelopathies. J Physiol 2010 1.09
46 Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1a. J Biol Chem 2005 1.08
47 Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK. J Neurosci 2010 1.06
48 Sensory neuron voltage-gated sodium channels as analgesic drug targets. Curr Opin Neurobiol 2008 1.06
49 Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur J Neurosci 2005 1.06
50 Electrophysiological characterization of the tetrodotoxin-resistant Na+ channel, Na(v)1.9, in mouse dorsal root ganglion neurons. Pflugers Arch 2004 1.04
51 RET signaling is required for survival and normal function of nonpeptidergic nociceptors. J Neurosci 2010 1.03
52 Nerve growth factor and pain. N Engl J Med 2010 1.03
53 Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11. FEBS Lett 2004 1.00
54 No pain, more gain. Nat Genet 2013 1.00
55 Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance. J Neurosci 2009 1.00
56 Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves. Mol Pain 2008 0.98
57 Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Brain Res Mol Brain Res 2003 0.96
58 The mechanosensitive cell line ND-C does not express functional thermoTRP channels. Neuropharmacology 2009 0.95
59 Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse. Mol Pain 2011 0.94
60 A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain. Proc Natl Acad Sci U S A 2011 0.94
61 Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay. Eur J Neurosci 2008 0.92
62 Roles of ASIC3, TRPV1, and NaV1.8 in the transition from acute to chronic pain in a mouse model of fibromyalgia. Mol Pain 2014 0.92
63 Sodium channels and mammalian sensory mechanotransduction. Mol Pain 2012 0.91
64 Transient receptor potential channels and mechanosensation. Annu Rev Neurosci 2013 0.91
65 A peripheral nervous system actin-binding protein regulates neurite outgrowth. Eur J Neurosci 2002 0.90
66 Mechanical allodynia. Pflugers Arch 2014 0.90
67 A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8. Mol Cell Neurosci 2009 0.89
68 Worm sensation! Mol Pain 2005 0.88
69 Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia. Genesis 2006 0.87
70 Novel mutations mapping to the fourth sodium channel domain of Nav1.7 result in variable clinical manifestations of primary erythromelalgia. Neuromolecular Med 2013 0.87
71 Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain. Mol Pain 2010 0.85
72 Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2). Hum Mol Genet 2013 0.84
73 Na(v) 1.8-null mice show stimulus-dependent deficits in spinal neuronal activity. Mol Pain 2006 0.84
74 Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice. PLoS One 2013 0.84
75 Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction. Ann Neurol 2014 0.82
76 Pyramidal cells of rodent presubiculum express a tetrodotoxin-insensitive Na+ current. J Physiol 2009 0.82
77 G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling. Mol Med 2012 0.82
78 Mechanisms of cold pain. Channels (Austin) 2007 0.82
79 Na(v)1.8 channelopathy in mutant mice deficient for myelin protein zero is detrimental to motor axons. Brain 2010 0.81
80 Splice variants of Na(V)1.7 sodium channels have distinct β subunit-dependent biophysical properties. PLoS One 2012 0.79
81 TRPs and pain. Handb Exp Pharmacol 2014 0.79
82 Sodium channels and pain. Handb Exp Pharmacol 2015 0.77
83 The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain. Pain 2015 0.77
84 Results in analgesia--Darwin 1, pharma 0. N Engl J Med 2013 0.76
85 Chapter 5 Molecular mechanisms of nociception and pain. Handb Clin Neurol 2006 0.76
86 Fat location defines sensation. Proc Natl Acad Sci U S A 2009 0.75
87 From transduction to pain sensation: defining genes, cells, and circuits. Pain 2011 0.75
88 Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Sci Rep 2017 0.75