Published in Biochim Biophys Acta on October 13, 2010
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell (2013) 3.71
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab (2012) 3.69
Mitochondrial disorders as windows into an ancient organelle. Nature (2012) 2.51
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J (2012) 2.36
Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol Rev (2012) 2.03
Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis. Am J Respir Crit Care Med (2012) 1.85
FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression. Cell Death Differ (2011) 1.59
G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes. J Am Soc Nephrol (2015) 1.47
Temperature during embryonic development has persistent effects on thermal acclimation capacity in zebrafish. Proc Natl Acad Sci U S A (2012) 1.27
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. Immunity (2016) 1.26
Multiple hits, including oxidative stress, as pathogenesis and treatment target in non-alcoholic steatohepatitis (NASH). Int J Mol Sci (2013) 1.25
Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Nucleic Acids Res (2012) 1.21
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance. Cell Cycle (2012) 1.19
Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget (2011) 1.19
The emerging role of Nrf2 in mitochondrial function. Free Radic Biol Med (2015) 1.15
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Hum Mol Genet (2013) 1.13
Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle. Mol Cell Endocrinol (2012) 1.12
Redox regulation of mitochondrial biogenesis. Free Radic Biol Med (2012) 1.11
Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health. Biochim Biophys Acta (2013) 1.10
Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction. Proc Natl Acad Sci U S A (2012) 1.10
Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. Biochim Biophys Acta (2012) 1.10
Molecular mechanisms of neonatal brain injury. Neurol Res Int (2012) 1.07
Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process. Int J Mol Sci (2013) 1.07
Mitochondrial dysfunction and insulin resistance: an update. Endocr Connect (2014) 1.02
The diabetes susceptibility gene Clec16a regulates mitophagy. Cell (2014) 1.02
The many roles of PGC-1α in muscle--recent developments. Metabolism (2014) 1.01
Resveratrol: A Focus on Several Neurodegenerative Diseases. Oxid Med Cell Longev (2015) 0.98
AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1. FASEB J (2013) 0.96
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Mol Cell Biol (2012) 0.96
Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells. Cancer Res (2013) 0.95
The optic nerve: a "mito-window" on mitochondrial neurodegeneration. Mol Cell Neurosci (2012) 0.95
PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression. J Biol Chem (2011) 0.95
Mitochondrial DNA: A Blind Spot in Neuroepigenetics. Biomol Concepts (2012) 0.95
Mitochondrial response to nutrient availability and its role in metabolic disease. EMBO Mol Med (2014) 0.94
Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet. FASEB J (2012) 0.94
Bigenomic regulation of cytochrome c oxidase in neurons and the tight coupling between neuronal activity and energy metabolism. Adv Exp Med Biol (2012) 0.94
Burn plus lipopolysaccharide augments endoplasmic reticulum stress and NLRP3 inflammasome activation and reduces PGC-1α in liver. Shock (2014) 0.93
Spatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cells. J Proteome Res (2012) 0.93
Nutrition and healthy ageing: calorie restriction or polyphenol-rich "MediterrAsian" diet? Oxid Med Cell Longev (2013) 0.93
Biochemical artifacts in experiments involving repeated biopsies in the same muscle. Physiol Rep (2014) 0.92
Mitochondria as a potential regulator of myogenesis. ScientificWorldJournal (2013) 0.92
Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant response. J Am Heart Assoc (2012) 0.92
Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia. Orphanet J Rare Dis (2013) 0.92
Molecular mechanisms and new treatment strategies for non-alcoholic steatohepatitis (NASH). Int J Mol Sci (2014) 0.92
The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1. Mol Cell Biol (2013) 0.92
PGC-1α modulates denervation-induced mitophagy in skeletal muscle. Skelet Muscle (2015) 0.91
Mitochondrial roles and cytoprotection in chronic liver injury. Biochem Res Int (2012) 0.90
Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin. Skelet Muscle (2014) 0.89
Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia. Front Behav Neurosci (2013) 0.89
The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun (2015) 0.89
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. Cell Death Dis (2013) 0.89
Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models. Br J Pharmacol (2014) 0.88
PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. PLoS One (2012) 0.87
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction. Oxid Med Cell Longev (2014) 0.87
SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis. Oncotarget (2016) 0.86
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice. Aging (Albany NY) (2012) 0.85
Regulation of Na(+)/K(+)-ATPase by nuclear respiratory factor 1: implication in the tight coupling of neuronal activity, energy generation, and energy consumption. J Biol Chem (2012) 0.85
Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration. Int J Cell Biol (2012) 0.85
PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase. Cell Rep (2015) 0.85
Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes (2012) 0.84
An Intimate Relationship between ROS and Insulin Signalling: Implications for Antioxidant Treatment of Fatty Liver Disease. Int J Cell Biol (2014) 0.84
Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation. J Biol Chem (2015) 0.83
Potential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies. Curr Neuropharmacol (2016) 0.83
Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux. Stem Cells Dev (2015) 0.83
Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence. J Biol Chem (2013) 0.83
Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons. eNeuro (2016) 0.82
Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem (2015) 0.82
Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury. J Pharmacol Exp Ther (2014) 0.82
Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection. Eur J Pharmacol (2013) 0.82
Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms. J Cereb Blood Flow Metab (2012) 0.82
GABP transcription factor (nuclear respiratory factor 2) is required for mitochondrial biogenesis. Mol Cell Biol (2014) 0.82
Metabolic characteristics and response to high altitude in Phrynocephalus erythrurus (Lacertilia: Agamidae), a lizard dwell at altitudes higher than any other living lizards in the world. PLoS One (2013) 0.82
The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone. Exp Cell Res (2012) 0.81
Melatonin Improves mitochondrial function by promoting MT1/SIRT1/PGC-1 alpha-dependent mitochondrial biogenesis in cadmium-induced hepatotoxicity in vitro. Toxicol Sci (2014) 0.81
In utero exposure to prepregnancy maternal obesity and postweaning high-fat diet impair regulators of mitochondrial dynamics in rat placenta and offspring. Physiol Genomics (2014) 0.81
Peroxisome proliferator-activated receptor γ co-activator 1-α as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis. J Biol Chem (2013) 0.81
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis. PLoS One (2014) 0.81
Resveratrol treatment during goat oocytes maturation enhances developmental competence of parthenogenetic and hand-made cloned blastocysts by modulating intracellular glutathione level and embryonic gene expression. J Assist Reprod Genet (2013) 0.81
Mitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer's Disease. Pharmaceuticals (Basel) (2012) 0.81
Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity. Am J Physiol Cell Physiol (2016) 0.81
Agent-Based Modeling of Mitochondria Links Sub-Cellular Dynamics to Cellular Homeostasis and Heterogeneity. PLoS One (2017) 0.80
Intermedin/adrenomedullin 2 polypeptide promotes adipose tissue browning and reduces high-fat diet-induced obesity and insulin resistance in mice. Int J Obes (Lond) (2016) 0.80
Prenatal Hypoxia Reduces Mitochondrial Protein Levels and Cytochrome c Oxidase Activity in Offspring Guinea Pig Hearts. Reprod Sci (2014) 0.79
Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice. Nat Commun (2014) 0.79
Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. Neurobiol Aging (2014) 0.79
Effects of Testosterone and Evoked Resistance Exercise after Spinal Cord Injury (TEREX-SCI): study protocol for a randomised controlled trial. BMJ Open (2017) 0.78
Endothelial fatty acid transport: role of vascular endothelial growth factor B. Physiology (Bethesda) (2013) 0.78
Modulation of the matrix redox signaling by mitochondrial Ca(2.). World J Biol Chem (2015) 0.78
Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle. J Aging Res (2012) 0.78
Amyloid precursor protein processing and bioenergetics. Brain Res Bull (2016) 0.78
Cardiac metabolic alterations in hypertensive obese pigs. Hypertension (2015) 0.78
In vivo RNA interference models of inducible and reversible Sirt1 knockdown in kidney cells. Am J Pathol (2014) 0.78
Dietary fucoxanthin increases metabolic rate and upregulated mRNA expressions of the PGC-1alpha network, mitochondrial biogenesis and fusion genes in white adipose tissues of mice. Mar Drugs (2014) 0.78
Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy. Am J Physiol Endocrinol Metab (2015) 0.78
Electroacupuncture inhibits weight gain in diet-induced obese rats by activating hypothalamic LKB1-AMPK signaling. BMC Complement Altern Med (2015) 0.78
The Therapeutic Potential of the Ketogenic Diet in Treating Progressive Multiple Sclerosis. Mult Scler Int (2015) 0.78
Electroacupuncture Upregulates SIRT1-Dependent PGC-1α Expression in SAMP8 Mice. Med Sci Monit (2015) 0.78
Inhibition of akt phosphorylation diminishes mitochondrial biogenesis regulators, tricarboxylic acid cycle activity and exacerbates recognition memory deficit in rat model of Alzheimer's disease. Cell Mol Neurobiol (2014) 0.77
Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock. Shock (2015) 0.77
Dietary whey protein stimulates mitochondrial activity and decreases oxidative stress in mouse female brain. Neurosci Lett (2013) 0.77
Brown adipose tissue: function and physiological significance. Physiol Rev (2004) 23.00
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell (1999) 19.48
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell (1998) 18.32
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet (2005) 16.79
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature (2002) 14.37
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature (2009) 10.59
Mitochondrial evolution. Science (1999) 8.59
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell (2004) 8.58
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A (2007) 8.23
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet (1998) 7.89
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J (2007) 7.30
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol (1995) 7.12
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest (2000) 7.06
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev (2004) 6.98
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest (2006) 6.85
Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev (2008) 6.57
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proc Natl Acad Sci U S A (2004) 6.53
AMPK in Health and Disease. Physiol Rev (2009) 6.38
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell (2007) 6.06
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol (2005) 5.80
The mitochondrial electron transport and oxidative phosphorylation system. Annu Rev Biochem (1985) 5.48
Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem (1991) 5.48
Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. J Biol Chem (1967) 5.20
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab (2006) 5.01
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol (2005) 4.99
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab (2005) 4.65
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem (2007) 4.58
The mitochondrial genome: structure, transcription, translation and replication. Biochim Biophys Acta (1999) 4.40
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. J Biol Chem (2001) 4.20
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem (2003) 4.12
Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1. Nature (2010) 4.12
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett (2007) 3.65
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis. Proc Natl Acad Sci U S A (2004) 3.65
A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev (1993) 3.60
The action of thyroid hormones at the cell level. Biochem J (1963) 3.42
A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator. Nat Genet (1997) 3.26
Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol Cell (2006) 3.16
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell Metab (2009) 3.06
Transcriptional control of energy homeostasis by the estrogen-related receptors. Endocr Rev (2008) 3.05
The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab (2007) 3.05
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell (2000) 3.00
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab (2007) 3.00
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol (2006) 2.86
A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. Genes Dev (1997) 2.84
The mechanism of action of thyroid hormones. Annu Rev Physiol (2000) 2.80
Retracted Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab (2008) 2.80
MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell (2007) 2.76
Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest (2005) 2.69
Nuclear control of respiratory gene expression in mammalian cells. J Cell Biochem (2006) 2.69
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol Cell Biol (2003) 2.65
Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality. Mol Cell Biol (1999) 2.61
Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol Cell Biol (2001) 2.58
Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev (2008) 2.58
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet (1999) 2.57
Nuclear receptor signaling and cardiac energetics. Circ Res (2004) 2.54
c-MYC apoptotic function is mediated by NRF-1 target genes. Genes Dev (2003) 2.51
Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators. Mol Cell Biol (2005) 2.46
Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab (2006) 2.37
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha. J Biol Chem (2002) 2.28
Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann N Y Acad Sci (2008) 2.27
PGC-1beta in the regulation of hepatic glucose and energy metabolism. J Biol Chem (2003) 2.20
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc Natl Acad Sci U S A (2007) 2.19
The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle (2008) 2.09
Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis. Proc Natl Acad Sci U S A (2007) 2.03
A cellular factor binds to the herpes simplex virus type 1 transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1. Mol Cell Biol (1990) 1.98
Regulation of oxidative phosphorylation in the mammalian cell. Am J Physiol (1990) 1.95
Mitochondrial DNA instability and peri-implantation lethality associated with targeted disruption of nuclear respiratory factor 1 in mice. Mol Cell Biol (2001) 1.83
ERRalpha: a metabolic function for the oldest orphan. Trends Endocrinol Metab (2008) 1.83
Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene. Oncogene (1995) 1.82
Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo. Biochem J (2003) 1.79
Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c. J Biol Chem (2000) 1.71
Assembly of the oxidative phosphorylation system in humans: what we have learned by studying its defects. Biochim Biophys Acta (2008) 1.66
Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Hum Mol Genet (2005) 1.60
Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance. J Physiol (2000) 1.56
The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP. EMBO J (2000) 1.55
Serum- and polypeptide growth factor-inducible gene expression in mouse fibroblasts. Prog Nucleic Acid Res Mol Biol (1998) 1.54
A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA. Mol Cell Biol (2008) 1.47
The ETS transcription factor GABPalpha is essential for early embryogenesis. Mol Cell Biol (2004) 1.46
Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons. J Biol Chem (2007) 1.41
Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism. Mol Endocrinol (2008) 1.37
PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth. Mol Cell Biol (2006) 1.32
Role of RIP140 in metabolic tissues: connections to disease. FEBS Lett (2007) 1.29
Use of fibroblast and lymphoblast cultures for detection of respiratory chain defects. Methods Enzymol (1996) 1.28
Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons? Gene (2005) 1.24
Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria. FEBS J (2010) 1.20
Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins. J Biol Chem (1987) 1.19
PGC-1-related coactivator complexes with HCF-1 and NRF-2beta in mediating NRF-2(GABP)-dependent respiratory gene expression. J Biol Chem (2008) 1.18
PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma. Biochem Biophys Res Commun (2003) 1.14
Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. J Biol Chem (1999) 1.13
Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria. J Biol Chem (2008) 1.09
Postnatal development of rat liver mitochondrial functions. The roles of protein synthesis and of adenine nucleotides. J Biol Chem (1988) 1.07
RIP140 expression is stimulated by estrogen-related receptor alpha during adipogenesis. J Biol Chem (2006) 1.07
Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits. J Biol Chem (2008) 1.04
Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression. J Biol Chem (1994) 1.03
Biogenesis of mitochondrial membrane proteins. Curr Opin Cell Biol (2009) 1.00
Structural organization and promoter analysis of the bovine cytochrome c oxidase subunit VIIc gene. A functional role for YY1. J Biol Chem (1997) 0.96
Heart mitochondrial DNA and enzyme changes during early human development. Mol Cell Biochem (2000) 0.93
Mouse models of oxidative phosphorylation defects: powerful tools to study the pathobiology of mitochondrial diseases. Biochim Biophys Acta (2008) 0.90
Regulation of murine cytochrome oxidase Vb gene expression in different tissues and during myogenesis. Role of a YY-1 factor-binding negative enhancer. J Biol Chem (1997) 0.90
Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa. J Biol Chem (1995) 0.88