Published in PLoS Genet on September 30, 2010
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Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin. Circ Res (2004) 2.63
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A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol (2007) 2.47
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Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis. Arterioscler Thromb Vasc Biol (2008) 1.62
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Genetic variation at the 9p21 locus predicts angiographic coronary artery disease prevalence but not extent and has clinical utility. Am Heart J (2008) 1.29
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Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men. Clin Chem (2006) 1.19
Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. PLoS One (2008) 1.17
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Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia. Am J Cardiol (2008) 0.97
Pathway and network analysis with high-density allelic association data. Methods Mol Biol (2009) 0.97
Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study. Clin Genet (2009) 0.95
Integrative predictive model of coronary artery calcification in atherosclerosis. Circulation (2009) 0.94
Statistical power of association using the extreme discordant phenotype design. Pharmacogenet Genomics (2006) 0.92
Overnight variability in transcutaneous carbon dioxide predicts vascular impairment in women. Exp Physiol (2008) 0.81
Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study. Atherosclerosis (2003) 0.81
Resampling reveals sample-level differential expression in clinical genome-wide studies. OMICS (2009) 0.81
Possible association of tumor necrosis factor receptor 2 gene polymorphism with severe hypertension using the extreme discordant phenotype design. Hypertens Res (2009) 0.79
Comparison of classification methods for detecting associations between SNPs and chick mortality. Genet Sel Evol (2009) 0.78
ExactFDR: exact computation of false discovery rate estimate in case-control association studies. Bioinformatics (2008) 0.76
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet (2002) 8.19
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med (2011) 7.16
Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA (2003) 6.60
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet (2012) 4.08
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Bacterial signatures in thrombus aspirates of patients with myocardial infarction. Circulation (2013) 2.81
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Vitamin D and attainment of peak bone mass among peripubertal Finnish girls: a 3-y prospective study. Am J Clin Nutr (2002) 2.75
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73
Interrelations between brachial endothelial function and carotid intima-media thickness in young adults: the cardiovascular risk in young Finns study. Circulation (2004) 2.72
A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments. BMC Genomics (2009) 2.70
Endothelial function is well preserved in obese patients with mild obstructive sleep apnea. Sleep Breath (2013) 2.67
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
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High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. Analyst (2009) 2.49
GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring. Bioinformatics (2006) 2.37
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
T-wave alternans predicts mortality in a population undergoing a clinically indicated exercise test. Eur Heart J (2007) 2.36
Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study. Circulation (2012) 2.32
Substantial intergenerational increases in body mass index are not explained by the fetal overnutrition hypothesis: the Cardiovascular Risk in Young Finns Study. Am J Clin Nutr (2007) 2.28
Genetically determined height and coronary artery disease. N Engl J Med (2015) 2.24
Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study. Circulation (2007) 2.15
High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis. J Am Coll Cardiol (2013) 2.15