Published in N Engl J Med on November 17, 2011
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. Circulation (2017) 2.76
The Study of Cardiovascular Risk in Adolescents--ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents. BMC Public Health (2015) 2.14
Status of cardiovascular disease and stroke in Hispanics/Latinos in the United States: a science advisory from the American Heart Association. Circulation (2014) 1.81
Improved rodent maternal metabolism but reduced intrauterine growth after vertical sleeve gastrectomy. Sci Transl Med (2013) 1.54
Does breastfeeding help to reduce the risk of childhood overweight and obesity? A propensity score analysis of data from the KiGGS study. PLoS One (2015) 1.44
Associations of childhood and adult obesity with left ventricular structure and function. Int J Obes (Lond) (2016) 1.40
Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metab (2017) 1.39
Responding to exercise-deficit disorder in youth: integrating wellness care into pediatric physical therapy. Pediatr Phys Ther (2013) 1.39
Overweight in early adulthood, adult weight change, and risk of type 2 diabetes, cardiovascular diseases, and certain cancers in men: a cohort study. Am J Epidemiol (2014) 1.37
Modeling obesity histories in cohort analyses of health and mortality. Epidemiology (2013) 1.36
Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions. Nutrition (2012) 1.33
Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: the International Childhood Cardiovascular Cohort Consortium. Circulation (2013) 1.26
Cardiovascular disease in childhood: the role of obesity. Eur J Pediatr (2013) 1.20
Body mass index and risk of incident hypertension over the life course: the Johns Hopkins Precursors Study. Circulation (2012) 1.17
Early life opportunities for prevention of diabetes in low and middle income countries. BMC Public Health (2012) 1.13
Obesity in young men, and individual and combined risks of type 2 diabetes, cardiovascular morbidity and death before 55 years of age: a Danish 33-year follow-up study. BMJ Open (2013) 1.13
Prevalence of hypertension in overweight and obese children from a large school-based population in Shanghai, China. BMC Public Health (2013) 1.10
Cohort Profile: the international childhood cardiovascular cohort (i3C) consortium. Int J Epidemiol (2012) 1.10
Laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity (AMOS): a prospective, 5-year, Swedish nationwide study. Lancet Diabetes Endocrinol (2017) 1.09
Overweight in childhood, adolescence and adulthood and cardiovascular risk in later life: pooled analysis of three british birth cohorts. PLoS One (2013) 1.06
Influence of stress in parents on child obesity and related behaviors. Pediatrics (2012) 1.03
The effect of obesity in adolescence on adult health status. Pediatrics (2013) 1.03
The Epidemiology of Obesity: A Big Picture. Pharmacoeconomics (2015) 1.02
High risk blood pressure and obesity increase the risk for left ventricular hypertrophy in African-American adolescents. J Pediatr (2012) 1.01
Indicated prevention of adult obesity: how much weight change is necessary for normalization of weight status in children? JAMA Pediatr (2013) 0.99
Diabetes and its comorbidities--where East meets West. Nat Rev Endocrinol (2013) 0.99
Evidence for transgenerational metabolic programming in Drosophila. Dis Model Mech (2013) 0.98
Bariatric surgery in morbidly obese adolescents: a systematic review and meta-analysis. Obes Surg (2015) 0.98
Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study. Int J Behav Nutr Phys Act (2014) 0.97
Body fat throughout childhood in 2647 healthy Danish children: agreement of BMI, waist circumference, skinfolds with dual X-ray absorptiometry. Eur J Clin Nutr (2014) 0.97
Evidence of lifestyle modification in the management of hypercholesterolemia. Curr Cardiol Rev (2013) 0.96
Anthropometric predictors of visceral adiposity in normal-weight and obese adolescents. Pediatr Diabetes (2013) 0.96
Recent clinical and translational advances in pediatric hypertension. Hypertension (2015) 0.95
Multi-Institutional Sharing of Electronic Health Record Data to Assess Childhood Obesity. PLoS One (2013) 0.94
Rapid increases in infant adiposity and overweight/obesity in childhood are associated with higher central and brachial blood pressure in early adulthood. J Hypertens (2014) 0.93
Metabolic syndrome risk profiles among African American adolescents: national health and nutrition examination survey, 2003-2010. Diabetes Care (2012) 0.93
Longitudinal trajectories of BMI and cardiovascular disease risk: the national longitudinal study of adolescent health. Obesity (Silver Spring) (2013) 0.93
Contributions of incidence and persistence to the prevalence of childhood obesity during the emerging epidemic in Denmark. PLoS One (2012) 0.92
Inconsistent Access to Food and Cardiometabolic Disease: The Effect of Food Insecurity. Curr Cardiovasc Risk Rep (2012) 0.91
Adolescent obesity, change in weight status, and hypertension: racial/ethnic variations. Hypertension (2012) 0.91
Shared care obesity management in 3-10 year old children: 12 month outcomes of HopSCOTCH randomised trial. BMJ (2013) 0.91
Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese. Sci Rep (2016) 0.90
Effectiveness of a diet and physical activity promotion strategy on the prevention of obesity in Mexican school children. BMC Public Health (2012) 0.90
Complication characteristics between young-onset type 2 versus type 1 diabetes in a UK population. BMJ Open Diabetes Res Care (2015) 0.89
Risk factors for cardiovascular disease and type 2 diabetes retained from childhood to adulthood predict adult outcomes: the Princeton LRC Follow-up Study. Int J Pediatr Endocrinol (2012) 0.89
Waist-to-Height Ratio Is a Better Anthropometric Index than Waist Circumference and BMI in Predicting Metabolic Syndrome among Obese Mexican Adolescents. Int J Endocrinol (2014) 0.89
Exergaming in Youth: Effects on Physical and Cognitive Health. Z Psychol (2013) 0.89
Development of hypertension in overweight adolescents: a review. Adolesc Health Med Ther (2015) 0.88
The effect of school-based physical activity interventions on body mass index: a meta-analysis of randomized trials. Clinics (Sao Paulo) (2013) 0.87
Blood pressure tracking in children and adolescents. Pediatr Nephrol (2013) 0.87
Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift. J Gerontol A Biol Sci Med Sci (2012) 0.87
Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine. Physiol Genomics (2013) 0.87
Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls. PLoS One (2013) 0.87
ADHD is a risk factor for overweight and obesity in children. J Dev Behav Pediatr (2013) 0.86
Anthropometric measurements in childhood and prediction of cardiovascular risk factors in adulthood: Kaunas cardiovascular risk cohort study. BMC Public Health (2015) 0.86
Obesity and Multiple Sclerosis: A Mendelian Randomization Study. PLoS Med (2016) 0.85
Comparison of total energy expenditure between school and summer months. Pediatr Obes (2013) 0.85
BMI and waist circumference; cross-sectional and prospective associations with blood pressure and cholesterol in 12-year-olds. PLoS One (2012) 0.85
Body mass index and height from infancy to adulthood and carotid intima-media thickness at 60 to 64 years in the 1946 British Birth Cohort Study. Arterioscler Thromb Vasc Biol (2014) 0.84
Physical, behavioural and genetic predictors of adult hypertension: the findings of the Kaunas Cardiovascular Risk Cohort study. PLoS One (2014) 0.84
Sleep duration predicts cardiometabolic risk in obese adolescents. J Pediatr (2014) 0.84
Insulin resistance. J Pediatr (2012) 0.84
High Overweight and Obesity in Fontan Patients: A 20-Year History. Pediatr Cardiol (2015) 0.83
Pharmacotherapy for childhood obesity: present and future prospects. Int J Obes (Lond) (2012) 0.83
Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children. J Am Heart Assoc (2014) 0.82
Children's report of lifestyle counseling differs by BMI status. Child Obes (2013) 0.82
Peripubertal-onset but not adult-onset obesity increases IGF-I and drives development of lean mass, which may lessen the metabolic impairment in adult obesity. Am J Physiol Endocrinol Metab (2012) 0.82
Behavioral Interventions and Cardiovascular Risk in Obese Youth: Current Findings and Future Directions. Curr Cardiovasc Risk Rep (2012) 0.82
Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn. FASEB J (2014) 0.81
Stress in obesity and associated metabolic and cardiovascular disorders. Scientifica (Cairo) (2012) 0.81
Assessment of endothelial dysfunction in childhood obesity and clinical use. Oxid Med Cell Longev (2013) 0.81
Pediatric obesity pharmacotherapy: current state of the field, review of the literature and clinical trial considerations. Int J Obes (Lond) (2016) 0.81
Plasminogen activator inhibitor-1, monocyte chemoattractant protein-1, e-selectin and C-reactive protein levels in response to 4-week very-high-fructose or -glucose diets. Eur J Clin Nutr (2013) 0.81
Heart rate variability and its relationship with central and general obesity in obese normotensive adolescents. Einstein (Sao Paulo) (2013) 0.81
Childhood obesity and coronary heart disease. N Engl J Med (2011) 0.81
Pediatric obesity. An introduction. Appetite (2015) 0.81
Epidemiology of elevated blood pressure and associated risk factors in Chinese children: the SNEC study. J Hum Hypertens (2015) 0.80
Associations of PON1 and genetic ancestry with obesity in early childhood. PLoS One (2013) 0.80
Relationships between obesity, glycemic control, and cardiovascular risk factors: a pooled analysis of cross-sectional data from Spanish patients with type 2 diabetes in the preinsulin stage. BMC Cardiovasc Disord (2014) 0.80
Prevalence of cardiometabolic risk factors and metabolic syndrome in obese Kuwaiti adolescents. Diabetes Metab Syndr Obes (2014) 0.80
Adolescent report of lifestyle counseling. Child Obes (2014) 0.80
Fluid intake and hydration status in obese vs normal weight children. Eur J Clin Nutr (2015) 0.80
Cardiovascular Health Promotion in Children: Challenges and Opportunities for 2020 and Beyond: A Scientific Statement From the American Heart Association. Circulation (2016) 0.80
Treatment of type 2 diabetes, lifestyle, GLP1 agonists and DPP4 inhibitors. World J Diabetes (2014) 0.79
Therapy of obese patients with cardiovascular disease. Curr Opin Pharmacol (2013) 0.79
Childhood maltreatment and BMI trajectories to mid-adult life: follow-up to age 50 y in a British birth cohort. PLoS One (2015) 0.79
Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease. PLoS Genet (2015) 0.79
Gestational weight gain: now and the future. Circulation (2012) 0.79
A socio-ecological approach promoting physical activity and limiting sedentary behavior in adolescence showed weight benefits maintained 2.5 years after intervention cessation. Int J Obes (Lond) (2014) 0.79
The associations between yogurt consumption, diet quality, and metabolic profiles in children in the USA. Eur J Nutr (2014) 0.78
Consequences of obesity and weight loss: a devil's advocate position. Obes Rev (2014) 0.78
Candy consumption in childhood is not predictive of weight, adiposity measures or cardiovascular risk factors in young adults: the Bogalusa Heart Study. J Hum Nutr Diet (2013) 0.78
Adolescent prediabetes in a high-risk Middle East country: a cross-sectional study. JRSM Open (2014) 0.78
Longitudinal investigation of adenovirus 36 seropositivity and human obesity: the Cardiovascular Risk in Young Finns Study. Int J Obes (Lond) (2015) 0.78
Birth weight, early life course BMI, and body size change: Chains of risk to adult inflammation? Soc Sci Med (2015) 0.78
Tracking of body mass index from 7 to 69 years of age. Int J Obes (Lond) (2016) 0.78
Reference values of body composition indices: the Korean National Health and Nutrition Examination Surveys. Yonsei Med J (2015) 0.78
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation (2005) 43.74
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
Global quantification of mammalian gene expression control. Nature (2011) 22.36
Evidence based physical activity for school-age youth. J Pediatr (2005) 13.50
Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet (2012) 10.53
Discovering microRNAs from deep sequencing data using miRDeep. Nat Biotechnol (2008) 10.17
Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr (2007) 9.60
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet (2007) 9.47
Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much? J Clin Oncol (2004) 7.36
Cubic AgPb(m)SbTe(2+m): bulk thermoelectric materials with high figure of merit. Science (2004) 7.07
Decline in physical activity in black girls and white girls during adolescence. N Engl J Med (2002) 7.06
Overweight in children and adolescents: pathophysiology, consequences, prevention, and treatment. Circulation (2005) 7.04
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev (2007) 6.71
Lipid screening and cardiovascular health in childhood. Pediatrics (2008) 6.62
Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA (2003) 6.60
Altered histone acetylation is associated with age-dependent memory impairment in mice. Science (2010) 6.38
A human snoRNA with microRNA-like functions. Mol Cell (2008) 5.84
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res (2011) 5.83
Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association. Hypertension (2006) 5.59
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet (2002) 5.38
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum (2005) 5.18
Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics (2004) 5.01
Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images. IEEE Trans Med Imaging (2009) 4.96
The relation of childhood BMI to adult adiposity: the Bogalusa Heart Study. Pediatrics (2005) 4.95
Childhood cardiovascular risk factors and carotid vascular changes in adulthood: the Bogalusa Heart Study. JAMA (2003) 4.88
Deep sequencing reveals 50 novel genes for recessive cognitive disorders. Nature (2011) 4.85
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev Cell (2005) 4.83
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Relation between the changes in physical activity and body-mass index during adolescence: a multicentre longitudinal study. Lancet (2005) 4.65
A decade of reversal: an analysis of 146 contradicted medical practices. Mayo Clin Proc (2013) 4.63
Sequence and analysis of rice chromosome 4. Nature (2002) 4.39
Ligand configurational entropy and protein binding. Proc Natl Acad Sci U S A (2007) 4.33
Transmit and receive transmission line arrays for 7 Tesla parallel imaging. Magn Reson Med (2005) 4.25
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science (2011) 4.16
Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet (2012) 4.08
Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature (2012) 4.00
Guidelines for lipid screening in children and adolescents: bringing evidence to the debate. Pediatrics (2012) 3.98
A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab (2003) 3.93
Estimating accuracy of RNA-Seq and microarrays with proteomics. BMC Genomics (2009) 3.87
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet (2008) 3.71
Intradiscal injection therapy for degenerative chronic discogenic low back pain with end plate Modic changes. Spine J (2010) 3.55
Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation. Hum Mutat (2007) 3.52
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A (2007) 3.50
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet (2007) 3.39
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. Nat Genet (2013) 3.39
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
E2-2 protein and Fuchs's corneal dystrophy. N Engl J Med (2010) 3.31
Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet (2010) 3.28
Rise in insulin resistance is associated with escalated telomere attrition. Circulation (2005) 3.27
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc Natl Acad Sci U S A (2007) 3.27
Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells. Cell (2012) 3.26
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. Nat Genet (2010) 3.24
Tracking of activity and sedentary behaviors in childhood: the Iowa Bone Development Study. Am J Prev Med (2005) 3.24
Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell (2008) 3.24
Frequency of abnormal carbohydrate metabolism and diabetes in a population-based screening of adolescents. J Pediatr (2005) 3.23
Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association. Hypertension (2009) 3.22
Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr (2006) 3.15
Beta-arrestin-mediated localization of smoothened to the primary cilium. Science (2008) 3.10
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J Immunol (2004) 3.10
The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med (2003) 3.07
Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev (2006) 2.99
Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell (2007) 2.96
Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation (2012) 2.95
Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: the Bogalusa Heart Study. Diabetes (2002) 2.89
Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol (2008) 2.86
Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr (2002) 2.84
Racial diversity of actionable mutations in non-small cell lung cancer. J Thorac Oncol (2015) 2.80
Preperitoneal single-port transvesical enucleation of the prostate (STEP) for large-volume BPH: one-year follow-up of Qmax, IPSS, and QoL. Urology (2012) 2.78
Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients. Crit Care Med (2015) 2.77
Single-incision transaxillary robotic thyroidectomy: challenges and limitations in a North American population. Otolaryngol Head Neck Surg (2012) 2.76
Vitamin D and attainment of peak bone mass among peripubertal Finnish girls: a 3-y prospective study. Am J Clin Nutr (2002) 2.75
KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary. Kidney Int (2009) 2.72
Interrelations between brachial endothelial function and carotid intima-media thickness in young adults: the cardiovascular risk in young Finns study. Circulation (2004) 2.72
Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the American Heart Association. Circulation (2013) 2.71
Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet (2002) 2.71