Published in Cell Cycle on December 01, 2010
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A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe. Cell Cycle (2013) 0.94
Mus81-Eme1 are essential components of a Holliday junction resolvase. Cell (2001) 5.37
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell (2007) 5.31
Structural and functional relationships of the XPF/MUS81 family of proteins. Annu Rev Biochem (2008) 3.32
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol Cell Biol (2000) 3.27
Single Holliday junctions are intermediates of meiotic recombination. Cell (2006) 3.15
DNA resection in eukaryotes: deciding how to fix the break. Nat Struct Mol Biol (2010) 2.81
Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat Cell Biol (2001) 2.62
Meiotic DNA breaks associated with recombination in S. pombe. Mol Cell (2000) 2.52
Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways. J Cell Sci (2000) 2.37
Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin. Genes Dev (2006) 2.28
Partner choice during meiosis is regulated by Hop1-promoted dimerization of Mek1. Mol Biol Cell (2005) 2.13
Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. Cell (2008) 1.98
The Chk2 protein kinase. DNA Repair (Amst) (2004) 1.85
Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion. Genetics (2003) 1.72
Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast. Mol Biol Cell (2003) 1.66
Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev (2005) 1.60
The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair, and adaptation. Exp Cell Res (2006) 1.52
The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability. Front Biosci (2008) 1.48
DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. Proc Natl Acad Sci U S A (2008) 1.46
Pachytene exit controlled by reversal of Mek1-dependent phosphorylation. Cell (2000) 1.44
Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis. Mol Cell Biol (2007) 1.38
Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast. Genes Dev (2006) 1.35
Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosis. PLoS Genet (2009) 1.32
Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions. Mol Cell Biol (2009) 1.29
A novel meiosis-specific protein of fission yeast, Meu13p, promotes homologous pairing independently of homologous recombination. EMBO J (2001) 1.26
The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast. EMBO J (2002) 1.21
Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol Cell (2009) 1.18
Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single class of oligonucleotides in fission yeast. PLoS Genet (2009) 1.13
Characterization of the activation domain of the Rad53 checkpoint kinase. Cell Cycle (2008) 1.11
SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association. J Biol Chem (2006) 1.07
A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae. Genome Res (2009) 1.07
Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast. J Cell Sci (2003) 1.07
Single molecule imaging of Tid1/Rdh54, a Rad54 homolog that translocates on duplex DNA and can disrupt joint molecules. J Biol Chem (2007) 1.06
Schizosaccharomyces pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double-strand breaks. Mol Biol Cell (2003) 1.03
Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination. Nucleic Acids Res (2004) 1.01
Yeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis. EMBO J (2009) 0.98
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. Mol Cell Biol (2008) 0.98
Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement. Curr Biol (2005) 0.97
Genetic analysis of meiotic recombination in Schizosaccharomyces pombe. Methods Mol Biol (2009) 0.95
Rad3-Cds1 mediates coupling of initiation of meiotic recombination with DNA replication. Mei4-dependent transcription as a potential target of meiotic checkpoint. J Biol Chem (2005) 0.95
Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1. J Biol Chem (2004) 0.94
Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation. J Biol Chem (2006) 0.94
Roles of Hop1 and Mek1 in meiotic chromosome pairing and recombination partner choice in Schizosaccharomyces pombe. Mol Cell Biol (2010) 0.92
Functional interactions of meiotic recombination factors Rdh54 and Dmc1. DNA Repair (Amst) (2008) 0.88
Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis. Genome Dyn Stab (2008) 0.88
Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60. J Cell Sci (2009) 0.82
The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation. Cell Cycle (2008) 0.80
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell (2006) 11.01
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell (2007) 5.31
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell (2009) 5.05
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell (2008) 4.26
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell (2010) 3.51
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol Cell Biol (2005) 3.25
Elastic modulus determination of normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci (2011) 3.19
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell (2009) 2.90
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55
Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin. Mol Cell (2009) 2.49
The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism. Mol Cell (2003) 2.44
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes Dev (2006) 2.41
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit. Nat Cell Biol (2009) 2.29
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev (2006) 2.27
Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell (2002) 2.23
Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast. Mol Cell Biol (2004) 2.20
Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol Cell Biol (2003) 2.19
The DNA damage response: sensing and signaling. Curr Opin Cell Biol (2004) 2.13
Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast. Mol Biol Cell (2003) 1.96
Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell (2006) 1.92
Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics (2002) 1.78
Lats2 is an essential mitotic regulator required for the coordination of cell division. J Biol Chem (2007) 1.75
Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion. Genetics (2003) 1.72
Protection of telomeres by a conserved Stn1-Ten1 complex. Proc Natl Acad Sci U S A (2007) 1.71
Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes. Mol Cell Biol (2003) 1.70
The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis. Cell Cycle (2011) 1.69
Indentation versus tensile measurements of Young's modulus for soft biological tissues. Tissue Eng Part B Rev (2011) 1.69
Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet (2011) 1.66
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat Struct Mol Biol (2011) 1.66
Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells. Nat Immunol (2005) 1.65
Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J (2008) 1.63
Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev (2005) 1.60
Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast. Cell Cycle (2010) 1.58
Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity (2005) 1.54
Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice. J Invest Dermatol (2007) 1.54
Lats2 is a negative regulator of myocyte size in the heart. Circ Res (2008) 1.53
The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1. Genes Dev (2010) 1.50
Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60. Mol Cell Biol (2003) 1.50
Burkholderia pseudomallei: animal models of infection. Trans R Soc Trop Med Hyg (2008) 1.48
Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. EMBO J (2006) 1.46
The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint. Mol Cell Biol (2003) 1.45
Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2. J Biol Chem (2004) 1.41
Characterisation of an acapsular mutant of Burkholderia pseudomallei identified by signature tagged mutagenesis. J Med Microbiol (2002) 1.37
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. EMBO J (2003) 1.35
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase. Genes Cells (2004) 1.35
Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta. Invest Ophthalmol Vis Sci (2004) 1.35
Morphine analgesia suppresses tumor growth and metastasis in a mouse model of cancer pain produced by orthotopic tumor inoculation. Eur J Pharmacol (2002) 1.32
SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF. Blood (2002) 1.32
Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients. DNA Res (2006) 1.31
Naive recirculating B cells mature simultaneously in the spleen and bone marrow. Blood (2006) 1.31
Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex. J Biol Chem (2005) 1.30
gammaH2A binds Brc1 to maintain genome integrity during S-phase. EMBO J (2010) 1.28
The effect of biophysical attributes of the ocular trabecular meshwork associated with glaucoma on the cell response to therapeutic agents. Biomaterials (2011) 1.28
Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair. Philos Trans R Soc Lond B Biol Sci (2011) 1.27
Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. EMBO J (2011) 1.26
Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice. Eur J Pharmacol (2005) 1.24
PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells. Biochem Biophys Res Commun (2008) 1.24
Itch-associated response induced by experimental dry skin in mice. Jpn J Pharmacol (2002) 1.23
CDK phosphorylation of Drc1 regulates DNA replication in fission yeast. Curr Biol (2002) 1.22
The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast. EMBO J (2002) 1.21
Isolation and expression profiling of genes upregulated in the peripheral blood cells of systemic lupus erythematosus patients. DNA Res (2006) 1.20
Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast. Mol Cell Biol (2003) 1.20
Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein. Genes Cells (2002) 1.18
Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury. J Biol Chem (2012) 1.18
Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast. Mol Cell Biol (2006) 1.18
RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. Mol Biol Cell (2003) 1.17
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J Clin Invest (2012) 1.16
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Adv Exp Med Biol (2007) 1.15
GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression. J Cell Sci (2009) 1.15
Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp Eye Res (2009) 1.14
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. EMBO J (2014) 1.14
Cooperative control of Crb2 by ATM family and Cdc2 kinases is essential for the DNA damage checkpoint in fission yeast. Mol Cell Biol (2005) 1.13
Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem (2010) 1.12
Signaling pathways that regulate cell division. Cold Spring Harb Perspect Biol (2012) 1.12
Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast. Genes Cells (2009) 1.12
Effect of latanoprost on the expression of matrix metalloproteinases and their tissue inhibitors in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2006) 1.12
Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast. PLoS Genet (2010) 1.11
The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis. Genes Cells (2006) 1.11
Compliance profile of the human cornea as measured by atomic force microscopy. Micron (2012) 1.10
Fission yeast meu14+ is required for proper nuclear division and accurate forespore membrane formation during meiosis II. J Cell Sci (2003) 1.10
Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus. J Virol (2012) 1.10
Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer. Clin Cancer Res (2008) 1.08
Use of stepwise subtraction to comprehensively isolate mouse genes whose transcription is up-regulated during spermiogenesis. EMBO Rep (2002) 1.07
Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues. Biomaterials (2010) 1.07
Biological properties of trabecular meshwork cells. Exp Eye Res (2008) 1.06
The applications of atomic force microscopy to vision science. Invest Ophthalmol Vis Sci (2010) 1.06
Suppression of anchorage-independent growth of human cancer cell lines by the TRIF52/periostin/OSF-2 gene. Exp Cell Res (2002) 1.06
Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway. Genes Cells (2005) 1.06
Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Mol Biol Cell (2006) 1.05
Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2012) 1.05
Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryot Cell (2005) 1.04
Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp Eye Res (2003) 1.04
The matricellular protein SPARC is expressed in human trabecular meshwork. Exp Eye Res (2003) 1.04
A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe. Toxicol Sci (2008) 1.04
Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein. Curr Biol (2010) 1.04