Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

PubWeight™: 6.13‹?› | Rank: Top 1%

🔗 View Article (PMID 21102434)

Published in Nature on November 21, 2010

Authors

Lucia Ricci-Vitiani1, Roberto Pallini, Mauro Biffoni, Matilde Todaro, Gloria Invernici, Tonia Cenci, Giulio Maira, Eugenio Agostino Parati, Giorgio Stassi, Luigi Maria Larocca, Ruggero De Maria

Author Affiliations

1: Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.

Articles citing this

(truncated to the top 100)

Tumor metastasis: molecular insights and evolving paradigms. Cell (2011) 10.34

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (2014) 6.09

Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med (2011) 4.91

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci U S A (2011) 3.48

Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A (2011) 3.45

Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev (2012) 3.44

Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell (2013) 3.32

Malignant glioma: lessons from genomics, mouse models, and stem cells. Cell (2012) 2.85

Cancer stem cells: the challenges ahead. Nat Cell Biol (2013) 2.78

Breast cancer stem cells, cytokine networks, and the tumor microenvironment. J Clin Invest (2011) 2.62

Understanding cancer stem cell heterogeneity and plasticity. Cell Res (2012) 2.39

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med (2012) 2.21

The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol (2011) 2.16

Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions. Angiogenesis (2014) 2.07

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer. J Clin Invest (2013) 2.03

Endothelial cell heterogeneity. Cold Spring Harb Perspect Med (2012) 1.88

Human endothelial progenitor cells. Cold Spring Harb Perspect Med (2012) 1.68

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci U S A (2011) 1.68

The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells? Cell Stem Cell (2015) 1.66

Stress response of glioblastoma cells mediated by miR-17-5p targeting PTEN and the passenger strand miR-17-3p targeting MDM2. Oncotarget (2012) 1.65

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells. Genes Dev (2012) 1.64

Cancer stem cells in gliomas: identifying and understanding the apex cell in cancer's hierarchy. Glia (2011) 1.63

Tumor cell vasculogenic mimicry: from controversy to therapeutic promise. Am J Pathol (2012) 1.58

Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond) (2012) 1.54

Molecular pathways: vasculogenic mimicry in tumor cells: diagnostic and therapeutic implications. Clin Cancer Res (2012) 1.52

Antiangiogenic therapy--evolving view based on clinical trial results. Nat Rev Clin Oncol (2012) 1.51

Advances in tenascin-C biology. Cell Mol Life Sci (2011) 1.50

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity. PLoS One (2011) 1.50

Reactive oxygen species in cancer stem cells. Antioxid Redox Signal (2012) 1.44

Mechanisms of glioma-associated neovascularization. Am J Pathol (2012) 1.39

Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers. Adv Mater (2011) 1.33

Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme. J Mol Med (Berl) (2013) 1.31

Surgical resection of malignant gliomas-role in optimizing patient outcome. Nat Rev Neurol (2013) 1.31

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited. Acta Neuropathol (2012) 1.30

Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS One (2011) 1.29

Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells. PLoS One (2011) 1.27

Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment. Clin Dev Immunol (2011) 1.24

Broad targeting of angiogenesis for cancer prevention and therapy. Semin Cancer Biol (2015) 1.24

Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment. Am J Pathol (2011) 1.23

Neovascularization after irradiation: what is the source of newly formed vessels in recurring tumors? J Natl Cancer Inst (2012) 1.19

Glioblastoma multiforme: State of the art and future therapeutics. Surg Neurol Int (2014) 1.18

Using the molecular classification of glioblastoma to inform personalized treatment. J Pathol (2014) 1.17

Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis. Adv Cancer Res (2012) 1.17

Glioblastoma-derived tumor cells induce vasculogenic mimicry through Flk-1 protein activation. J Biol Chem (2012) 1.16

Dedifferentiation and reprogramming: origins of cancer stem cells. EMBO Rep (2014) 1.16

A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. J Natl Compr Canc Netw (2011) 1.16

CD90 is identified as a candidate marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Mol Cell Proteomics (2011) 1.16

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Genes Dev (2012) 1.15

Brain tumor stem cells: Molecular characteristics and their impact on therapy. Mol Aspects Med (2013) 1.14

Laminin alpha 2 enables glioblastoma stem cell growth. Ann Neurol (2012) 1.13

CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry. Cancer Res (2012) 1.13

Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer. Cell Stem Cell (2015) 1.13

Tumor microenvironment in the brain. Cancers (Basel) (2012) 1.12

Angiogenesis in glioblastoma. N Engl J Med (2013) 1.11

Transdifferentiation of glioblastoma stem-like cells into mural cells drives vasculogenic mimicry in glioblastomas. J Neurosci (2012) 1.10

Neoplastic cells are a rare component in human glioblastoma microvasculature. Oncotarget (2012) 1.09

A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review). Oncol Lett (2013) 1.09

Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. J Natl Cancer Inst (2015) 1.08

Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan. Int J Cell Biol (2013) 1.07

Reactive oxygen species in normal and tumor stem cells. Adv Cancer Res (2014) 1.06

FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells. Cancer Res (2015) 1.06

Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma. J Clin Oncol (2015) 1.06

Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma. CNS Oncol (2013) 1.05

Vascular endothelial growth factor receptor 2 (VEGFR-2) plays a key role in vasculogenic mimicry formation, neovascularization and tumor initiation by Glioma stem-like cells. PLoS One (2013) 1.05

Bringing the heavy: carbon ion therapy in the radiobiological and clinical context. Radiat Oncol (2014) 1.03

Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche. Cancer Res (2013) 1.03

Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma. Nat Commun (2014) 1.02

The evolving landscape of glioblastoma stem cells. Curr Opin Neurol (2013) 1.02

Oct-4+/Tenascin C+ neuroblastoma cells serve as progenitors of tumor-derived endothelial cells. Cell Res (2011) 1.02

Glioblastoma-initiating cells: relationship with neural stem cells and the micro-environment. Cancers (Basel) (2013) 1.01

Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'? Mol Oncol (2011) 1.01

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis. Proc Natl Acad Sci U S A (2011) 1.01

VEGFR-1 mediates endothelial differentiation and formation of blood vessels in a murine model of infantile hemangioma. Am J Pathol (2011) 1.01

Investigating the link between molecular subtypes of glioblastoma, epithelial-mesenchymal transition, and CD133 cell surface protein. PLoS One (2013) 1.01

Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2. Oncotarget (2015) 1.01

Advanced research on vasculogenic mimicry in cancer. J Cell Mol Med (2015) 1.00

Nanoparticles of carbon allotropes inhibit glioblastoma multiforme angiogenesis in ovo. Int J Nanomedicine (2011) 1.00

Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme? ASN Neuro (2011) 1.00

Glioblastoma multiforme therapy and mechanisms of resistance. Pharmaceuticals (Basel) (2013) 1.00

Isolation and expansion of human and mouse brain microvascular endothelial cells. Nat Protoc (2013) 1.00

Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival. Oncotarget (2013) 0.99

A task-based approach for Gene Ontology evaluation. J Biomed Semantics (2013) 0.99

Cancer: Tumour stem cells switch sides. Nature (2010) 0.98

Hallmarks in colorectal cancer: angiogenesis and cancer stem-like cells. World J Gastroenterol (2014) 0.98

The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it. Endocr Relat Cancer (2013) 0.96

Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo. Oncogene (2012) 0.96

CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment. Front Cell Neurosci (2014) 0.96

Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas. Br J Cancer (2011) 0.96

Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells. PLoS One (2013) 0.96

βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer. PLoS One (2013) 0.96

The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence. Expert Rev Neurother (2015) 0.96

Nitric oxide inhibits hetero-adhesion of cancer cells to endothelial cells: restraining circulating tumor cells from initiating metastatic cascade. Sci Rep (2014) 0.95

Cellular host responses to gliomas. PLoS One (2012) 0.95

Twisted tango: brain tumor neurovascular interactions. Nat Neurosci (2011) 0.95

Radiotherapy and the tumor stroma: the importance of dose and fractionation. Front Oncol (2014) 0.95

Vasculogenic mimicry: a novel target for glioma therapy. Chin J Cancer (2013) 0.95

Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms. J Cell Mol Med (2013) 0.95

CDH5 is specifically activated in glioblastoma stemlike cells and contributes to vasculogenic mimicry induced by hypoxia. Neuro Oncol (2013) 0.94

Innovative therapeutic strategies in the treatment of brain metastases. Int J Mol Sci (2013) 0.94

Glioblastoma cancer stem-like cells: implications for pathogenesis and treatment. Cancer J (2012) 0.94

Articles cited by this

Identification of human brain tumour initiating cells. Nature (2004) 38.87

Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res (2004) 14.73

A perivascular niche for brain tumor stem cells. Cancer Cell (2007) 11.55

Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol (1999) 7.66

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res (2006) 6.77

Brain tumour stem cells. Nat Rev Cancer (2006) 5.84

Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer (2007) 4.54

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells. Nat Med (2003) 4.02

Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat Rev Cancer (2003) 3.93

Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell (2010) 3.82

Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas. N Engl J Med (2004) 3.63

Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 3.60

Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ (2006) 3.12

Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1. Cancer Res (2009) 2.80

Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res (2004) 2.78

Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature (2004) 2.54

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme. Clin Cancer Res (2008) 2.52

Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications. Am J Pathol (2007) 1.99

Tumor origin of endothelial cells in human neuroblastoma. J Clin Oncol (2007) 1.62

Mesenchymal differentiation of glioblastoma stem cells. Cell Death Differ (2008) 1.48

Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death. J Exp Med (2004) 1.38

In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors. Hum Gene Ther (2003) 1.22

Articles by these authors

Identification and expansion of human colon-cancer-initiating cells. Nature (2006) 24.44

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res (2009) 7.98

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol (2010) 7.73

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell (2007) 7.05

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J (2007) 6.26

The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med (2008) 5.74

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res (2009) 4.47

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential. Eur J Cancer (2007) 3.80

Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling. Circ Res (2009) 3.25

The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms. Cancer Res (2008) 3.21

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A (2002) 3.18

Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer (2012) 2.76

Colon cancer stem cells: promise of targeted therapy. Gastroenterology (2010) 2.58

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme. Clin Cancer Res (2008) 2.52

The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues. Development (2002) 2.50

Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells. Blood (2011) 2.20

The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res (2010) 2.12

Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma. Acta Neurochir (Wien) (2012) 2.06

Intrapelvic sciatic notch schwannoma: microsurgical excision using the infragluteal approach. J Neurosurg (2013) 2.03

Targeted therapy with bevacizumab and erlotinib tailored to the molecular profile of patients with recurrent glioblastoma. Preliminary experience. Acta Neurochir (Wien) (2012) 1.99

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis. Nat Cell Biol (2008) 1.97

Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia (2006) 1.82

Neurosphere and neurosphere-forming cells: morphological and ultrastructural characterization. Brain Res (2003) 1.77

Efficient killing of human colon cancer stem cells by gammadelta T lymphocytes. J Immunol (2009) 1.76

Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging. Stem Cells (2015) 1.75

Hedgehog controls neural stem cells through p53-independent regulation of Nanog. EMBO J (2010) 1.73

Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Res (2010) 1.73

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp Hematol (2008) 1.68

Primary empty sella. J Clin Endocrinol Metab (2005) 1.67

Anemia in Hodgkin's lymphoma: the role of interleukin-6 and hepcidin. J Clin Oncol (2010) 1.66

MicroRNAs and prostate cancer. Endocr Relat Cancer (2010) 1.63

Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study. Blood (2011) 1.62

Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy. PLoS One (2011) 1.58

The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice. PLoS One (2008) 1.56

Regulated expression of MUC1 epithelial antigen in erythropoiesis. Br J Haematol (2003) 1.56

Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts. Int J Cancer (2008) 1.55

Molecular analysis of immunoglobulin variable genes in human immunodeficiency virus-related non-Hodgkin's lymphoma reveals implications for disease pathogenesis and histogenesis. Haematologica (2008) 1.54

Colon cancer stem cells. J Mol Med (Berl) (2009) 1.53

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell (2012) 1.50

Mutations of the BIK gene in human peripheral B-cell lymphomas. Genes Chromosomes Cancer (2003) 1.50

Anemia in diffuse large B-cell non-Hodgkin lymphoma: the role of interleukin-6, hepcidin and erythropoietin. Leuk Lymphoma (2013) 1.47

Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma. J Neurosurg (2011) 1.46

Primary plasma cell leukemia followed by testicular plasmacytoma. Int J Hematol (2011) 1.44

Association between polymorphisms rs1333040 and rs7865618 of chromosome 9p21 and sporadic brain arteriovenous malformations. Cerebrovasc Dis (2014) 1.42

Endothelial progenitor cells in HIV-positive patients: what are we talking about? J Acquir Immune Defic Syndr (2013) 1.42

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis. Haematologica (2009) 1.40

Islet beta-cell apoptosis triggered in vivo by interleukin-1beta is not related to the inducible nitric oxide synthase pathway: evidence for mitochondrial function impairment and lipoperoxidation. Endocrinology (2003) 1.39

Isolation and culture of human muscle-derived stem cells able to differentiate into myogenic and neurogenic cell lineages. Lancet (2004) 1.39

Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death. J Exp Med (2004) 1.38

Tumor and its microenvironment: a synergistic interplay. Semin Cancer Biol (2013) 1.37

Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells. Cancer Res (2010) 1.36

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice. Gastroenterology (2010) 1.36

Clivus metastases: report of seven patients and literature review. Acta Neurochir (Wien) (2009) 1.34

Human fetal aorta contains vascular progenitor cells capable of inducing vasculogenesis, angiogenesis, and myogenesis in vitro and in a murine model of peripheral ischemia. Am J Pathol (2007) 1.31

IL-4-mediated drug resistance in colon cancer stem cells. Cell Cycle (2007) 1.29

Transplantation of low dose CD34+KDR+ cells promotes vascular and muscular regeneration in ischemic limbs. FASEB J (2004) 1.27

Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol (2002) 1.27

Cancer stem cells and chemosensitivity. Clin Cancer Res (2011) 1.26

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure. Cardiovasc Res (2008) 1.26

Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications. Clin Cancer Res (2007) 1.25

Chordoma of the skull base: predictors of tumor recurrence. J Neurosurg (2003) 1.24

Caveolin-1 tumor-promoting role in human melanoma. Int J Cancer (2009) 1.23

Homologous transplantation of neural stem cells to the injured spinal cord of mice. Neurosurgery (2005) 1.22

MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors. Br J Haematol (2008) 1.22

V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells. J Immunol (2010) 1.20

Role of L-type Ca2+ channels in neural stem/progenitor cell differentiation. Eur J Neurosci (2006) 1.20

Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic myeloproliferative diseases and is independent of the V617F JAK-2 mutation. Blood (2007) 1.19

The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma. Clin Cancer Res (2011) 1.18

IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins. J Immunol (2004) 1.18

The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand. J Clin Endocrinol Metab (2006) 1.18

DNA damage repair pathways in cancer stem cells. Mol Cancer Ther (2012) 1.16

Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction. Cancer Res (2005) 1.15