Published in Surgery on December 01, 2010
Follicular variant of papillary thyroid cancer: encapsulated, nonencapsulated, and diffuse: distinct biologic and clinical entities. Arch Otolaryngol Head Neck Surg (2012) 0.96
Clinical utility of immunohistochemistry for the detection of the BRAF v600e mutation in papillary thyroid carcinoma. Surgery (2013) 0.90
Clinical and therapeutic implications of Sprouty2 feedback dysregulation in BRAF V600E-mutation-positive papillary thyroid cancer. Surgery (2013) 0.79
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RAS oncogenes: weaving a tumorigenic web. Nat Rev Cancer (2011) 6.45
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature (2013) 4.71
Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome. Nat Genet (2006) 4.68
Redox-dependent downregulation of Rho by Rac. Nat Cell Biol (2003) 4.46
Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial. Lancet (2008) 4.35
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell (2004) 4.23
Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell (2012) 4.16
Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol (2007) 3.68
Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell (2003) 3.66
Modulation of signalling by Sprouty: a developing story. Nat Rev Mol Cell Biol (2004) 3.46
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol (2002) 3.08
Direct coupling of the cell cycle and cell death machinery by E2F. Nat Cell Biol (2002) 3.00
Membrane-dependent signal integration by the Ras activator Son of sevenless. Nat Struct Mol Biol (2008) 2.82
Regulating the regulator: post-translational modification of RAS. Nat Rev Mol Cell Biol (2011) 2.81
In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha. J Clin Invest (2009) 2.53
Psychopathology among New York city public school children 6 months after September 11. Arch Gen Psychiatry (2005) 2.48
Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors. Nature (2007) 2.43
Prostate cancer, version 2.2014. J Natl Compr Canc Netw (2014) 2.40
Structural analysis of autoinhibition in the Ras activator Son of sevenless. Cell (2004) 2.38
Role of boundary conditions in an experimental model of epithelial wound healing. Am J Physiol Cell Physiol (2006) 2.01
An orthosteric inhibitor of the Ras-Sos interaction. Nat Chem Biol (2011) 1.91
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med (2012) 1.82
Differential modification of Ras proteins by ubiquitination. Mol Cell (2006) 1.80
betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Mol Cell (2009) 1.77
Regulation of ras signaling dynamics by Sos-mediated positive feedback. Curr Biol (2006) 1.70
Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas. Cancer Res (2006) 1.61
Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells. Cancer Cell (2010) 1.58
A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc Natl Acad Sci U S A (2006) 1.57
Analysis of the nerve branches to the orbicularis oculi muscle of the lower eyelid in fresh cadavers. Plast Reconstr Surg (2005) 1.56
Combined thermo-chemotherapy for recurrent bladder cancer after bacillus Calmette-Guerin. J Urol (2009) 1.54
hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl. Curr Biol (2003) 1.52
Ras/MAPK signaling from endomembranes. Mol Oncol (2009) 1.51
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology (2006) 1.48
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. Genes Dev (2003) 1.48
Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells. Clin Cancer Res (2008) 1.43
The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways. Proc Natl Acad Sci U S A (2008) 1.42
Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. J Leukoc Biol (2009) 1.37
Prevention of radiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (SOD2) transgene. Radiat Res (2003) 1.35
The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins. Proc Natl Acad Sci U S A (2002) 1.33
Fast rendering of diffusion curves with triangles. IEEE Comput Graph Appl (2014) 1.33
Prostate cancer, version 1.2014. J Natl Compr Canc Netw (2013) 1.32
The structural basis for the transition from Ras-GTP to Ras-GDP. Proc Natl Acad Sci U S A (2002) 1.32
Design, synthesis, and biological evaluation of new-generation taxoids. J Med Chem (2008) 1.29
Tall cell variant of papillary thyroid carcinoma without extrathyroid extension: biologic behavior and clinical implications. Thyroid (2007) 1.29
Feedback regulation of Ras signaling by Rabex-5-mediated ubiquitination. Curr Biol (2010) 1.27
APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus. Genes Dev (2008) 1.26
Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis. Nat Commun (2012) 1.26
Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells. Cancer Res (2004) 1.23
The two hats of SOS. Sci STKE (2002) 1.22
Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc Natl Acad Sci U S A (2010) 1.22
Implications for clinical staging of metastatic cutaneous squamous carcinoma of the head and neck based on a multicenter study of treatment outcomes. Cancer (2006) 1.22
VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression. Cancer Res (2012) 1.21
Structure of the G60A mutant of Ras: implications for the dominant negative effect. J Biol Chem (2005) 1.21
Enhancing insulin-use safety in hospitals: Practical recommendations from an ASHP Foundation expert consensus panel. Am J Health Syst Pharm (2013) 1.21
Transducible peptide therapy for uveal melanoma and retinoblastoma. Arch Ophthalmol (2002) 1.20
Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless. Proc Natl Acad Sci U S A (2005) 1.20
Pancreatic duct epithelial cell isolation and cultivation in two-dimensional and three-dimensional culture systems. Methods Enzymol (2006) 1.19
Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker. Cancer Res (2004) 1.16
Nanoporous microsystems for islet cell replacement. Adv Drug Deliv Rev (2004) 1.16
Cyclophosphamide-induced bladder inflammation sensitizes and enhances P2X receptor function in rat bladder sensory neurons. J Neurophysiol (2007) 1.14
Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between. Cell Res (2005) 1.13
Tandem histone folds in the structure of the N-terminal segment of the ras activator Son of Sevenless. Structure (2003) 1.12
Two-stage prosthetic breast reconstruction using AlloDerm including outcomes of different timings of radiotherapy. Plast Reconstr Surg (2012) 1.11
Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia. J Clin Psychopharmacol (2010) 1.11
Spatial regulation of EGFR signaling by Sprouty2. Curr Biol (2007) 1.09
EZH2 couples pancreatic regeneration to neoplastic progression. Genes Dev (2012) 1.07
Pulmonary irradiation-induced expression of VCAM-I and ICAM-I is decreased by manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) gene therapy. Biol Blood Marrow Transplant (2002) 1.05
Regulation of sprouty stability by Mnk1-dependent phosphorylation. Mol Cell Biol (2006) 1.03
Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. Blood (2009) 1.03
Regulation of RAS oncogenicity by acetylation. Proc Natl Acad Sci U S A (2012) 1.02
Tailoring width of microfabricated nanochannels to solute size can be used to control diffusion kinetics. J Control Release (2005) 1.02
Fibronectin growth factor-binding domains are required for fibroblast survival. J Invest Dermatol (2010) 1.02
Environmental air pollution has decremental effects on pulmonary function test parameters up to one week after exposure. Am J Med Sci (2009) 1.01
Thermal effects of endoscopy in a human temporal bone model: implications for endoscopic ear surgery. Laryngoscope (2014) 1.00
Allosteric gating of Son of sevenless activity by the histone domain. Proc Natl Acad Sci U S A (2010) 0.98
Thyroid cancers detected by imaging are not necessarily small or early stage. Thyroid (2013) 0.98
The pleckstrin homology (PH) domain-interacting protein couples the insulin receptor substrate 1 PH domain to insulin signaling pathways leading to mitogenesis and GLUT4 translocation. Mol Cell Biol (2002) 0.98
Ras and Rac as activators of reactive oxygen species (ROS). Methods Mol Biol (2002) 0.98
Developmental pattern formation: insights from physics and biology. Science (2012) 0.97
Follicular variant of papillary thyroid cancer: encapsulated, nonencapsulated, and diffuse: distinct biologic and clinical entities. Arch Otolaryngol Head Neck Surg (2012) 0.96
Signaling endosomes: seeing is believing. Curr Opin Cell Biol (2010) 0.95
The association of higher levels of within-normal-limits liver enzymes and the prevalence of the metabolic syndrome. Cardiovasc Diabetol (2010) 0.92
Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells. J Pharmacol Exp Ther (2006) 0.91
Clinical utility of immunohistochemistry for the detection of the BRAF v600e mutation in papillary thyroid carcinoma. Surgery (2013) 0.90
Imaging and review of a large pre-auricular pilomatrixoma in a child. World J Radiol (2012) 0.90
Micro-inflammatory changes in asymptomatic healthy adults during bouts of respiratory tract infections in the community: potential triggers for atherothrombotic events. Atherosclerosis (2009) 0.90
Characterization of a Ras mutant with identical GDP- and GTP-bound structures . Biochemistry (2009) 0.89
Elevated resting heart rate is associated with the metabolic syndrome. Cardiovasc Diabetol (2009) 0.89
A retrospective analysis of outcomes using three common methods for immediate breast reconstruction. Plast Reconstr Surg (2008) 0.88
The challenge of implementing and sustaining integrated dual disorders treatment programs. Community Ment Health J (2002) 0.88
Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression. J Clin Invest (2013) 0.88
May-Thurner syndrome. Circulation (2014) 0.87
Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap. Nat Chem Biol (2013) 0.87
Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. J Virol (2012) 0.86
Genetic and electrophysiological characteristics of recurrent acute pancreatitis. J Pediatr Gastroenterol Nutr (2015) 0.84
Autoinhibition of Sos by intramolecular interactions. Front Biosci (2002) 0.84
Telephone conversation impairs sustained visual attention via a central bottleneck. Psychon Bull Rev (2008) 0.83
Exposure to the World Trade Center attack and the use of cigarettes and alcohol among New York City public high-school students. Am J Public Health (2006) 0.83
Ras oncogene and inflammation: partners in crime. Cell Cycle (2005) 0.83
Ethnic groups and high sensitivity C-reactive protein in Israel. Biomarkers (2008) 0.83