The impact of structural proteomics on biotechnology.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 21415888)

Published in Biotechnol Genet Eng Rev on January 01, 2010

Authors

Babu Manjasetty1, Andrew Turnbull, Santosh Panjikar

Author Affiliations

1: Proteomics and Bioinformatics Research Group, Research and Industry Incubation Center, Dayananda Sagar Institutions, Bangalore, India. babu.manjasetty@gmail.com

Articles by these authors

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. EMBO J (2008) 2.12

On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr D Biol Crystallogr (2007) 1.78

Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. J Am Chem Soc (2008) 1.50

Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries. Chem Biol (2007) 1.46

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics. Proteomics (2008) 1.43

Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs. Structure (2007) 1.34

The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis. J Biol Chem (2006) 1.34

The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. Plant Cell (2006) 1.32

On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength. Acta Crystallogr D Biol Crystallogr (2005) 1.30

C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain. J Mol Biol (2008) 1.28

Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J Biol Chem (2005) 1.26

On the influence of the incident photon energy on the radiation damage in crystalline biological samples. J Synchrotron Radiat (2005) 1.07

Structural insights into the mechanism of protein O-fucosylation. PLoS One (2011) 1.06

Structure of the motor subunit of type I restriction-modification complex EcoR124I. Nat Struct Mol Biol (2008) 1.06

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation. Mol Microbiol (2013) 1.06

Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family. Plant Cell (2007) 1.05

Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure (2008) 1.05

3D-Structure and function of strictosidine synthase--the key enzyme of monoterpenoid indole alkaloid biosynthesis. Plant Physiol Biochem (2008) 1.02

Structural and functional aspects of the sensor histidine kinase PrrB from Mycobacterium tuberculosis. Structure (2006) 1.02

The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J Biol Chem (2004) 1.00

Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J (2006) 1.00

The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature (2013) 1.00

Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc Natl Acad Sci U S A (2012) 0.98

The three-dimensional structure of the extracellular adhesion domain of the sialic acid-binding adhesin SabA from Helicobacter pylori. J Biol Chem (2013) 0.96

Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex. EMBO J (2011) 0.96

Crystal structures of a poplar thioredoxin peroxidase that exhibits the structure of glutathione peroxidases: insights into redox-driven conformational changes. J Mol Biol (2007) 0.96

Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion. PLoS One (2011) 0.95

Structural basis for the oxidation of protein-bound sulfur by the sulfur cycle molybdohemo-enzyme sulfane dehydrogenase SoxCD. J Biol Chem (2010) 0.91

The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae. J Struct Biol (2012) 0.90

Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers. J Mol Biol (2007) 0.89

The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J Biol Chem (2007) 0.88

High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor. Acta Biochim Pol (2007) 0.88

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.86

Structure of lambda CII: implications for recognition of direct-repeat DNA by an unusual tetrameric organization. Proc Natl Acad Sci U S A (2005) 0.85

Metal binding to porcine pancreatic elastase: calcium or not calcium. Acta Crystallogr D Biol Crystallogr (2002) 0.85

Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.85

High-resolution structure of Bombyx mori lipoprotein 7: crystallographic determination of the identity of the protein and its potential role in detoxification. Acta Crystallogr D Biol Crystallogr (2012) 0.85

On the routine use of soft X-rays in macromolecular crystallography. Part II. Data-collection wavelength and scaling models. Acta Crystallogr D Biol Crystallogr (2003) 0.85

Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. J Mol Biol (2010) 0.84

Structural characterization of the multidomain regulatory protein Rv1364c from Mycobacterium tuberculosis. Structure (2011) 0.84

Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX. Acta Crystallogr D Biol Crystallogr (2013) 0.84

Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity. J Struct Biol (2011) 0.83

On the routine use of soft X-rays in macromolecular crystallography. Part V. Molecular replacement and anomalous scattering. Acta Crystallogr D Biol Crystallogr (2011) 0.83

Additional phase information from UV damage of selenomethionine labelled proteins. J Synchrotron Radiat (2011) 0.83

Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids. Angew Chem Int Ed Engl (2009) 0.82

A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis. J Biol Chem (2006) 0.82

Scaffold tailoring by a newly detected Pictet-Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework. J Am Chem Soc (2012) 0.81

RhoB can adopt a Mg2+ free conformation prior to GEF binding. Proteins (2008) 0.81

Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis. J Struct Funct Genomics (2009) 0.81

Structural insight in histo-blood group binding by the F18 fimbrial adhesin FedF. Mol Microbiol (2012) 0.81

Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli. Protein Sci (2008) 0.81

Structures of alkaloid biosynthetic glucosidases decode substrate specificity. ACS Chem Biol (2011) 0.81

Purification, crystallization and preliminary X-ray analysis of the HsdR subunit of the EcoR124I endonuclease from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.81

Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81

Structural biology in plant natural product biosynthesis--architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis. Nat Prod Rep (2007) 0.79

Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically involved in Rauvolfia alkaloid biosynthesis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.79

The X-ray structure of the N-terminal domain of PILB from Neisseria meningitidis reveals a thioredoxin-fold. J Mol Biol (2006) 0.79

In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures. J Struct Biol (2012) 0.78

Structure of the C-terminal domain of nsp4 from feline coronavirus. Acta Crystallogr D Biol Crystallogr (2009) 0.78

Purification, crystallization and X-ray diffraction analysis of pavine N-methyltransferase from Thalictrum flavum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.77

Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production. Biotechnol Rep (Amst) (2014) 0.77

Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis. PLoS One (2013) 0.77

The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules. J Struct Biol (2011) 0.77

Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling. Acta Crystallogr D Biol Crystallogr (2012) 0.77

Post-translational modification and extended glycosylation pattern of a plant latex peroxidase of native source characterized by X-ray crystallography. FEBS J (2014) 0.76

Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding. J Biol Chem (2012) 0.76

The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces. Acta Crystallogr D Biol Crystallogr (2009) 0.76

Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY from Chlorobium limicola f. thiosulfatophilum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.76

Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1). Planta (2012) 0.76

Expression, purification and X-ray analysis of 1,3-propanediol dehydrogenase (Aq_1145) from Aquifex aeolicus VF5. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.75

Structure of the apo form of the catabolite control protein A (CcpA) from Bacillus megaterium with a DNA-binding domain. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.75

Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75

Crystallization and preliminary X-ray crystallographic studies of an oligomeric species of a refolded C39 peptidase-like domain of the Escherichia coli ABC transporter haemolysin B. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75

Purification, crystallization and preliminary crystallographic analysis of banyan peroxidase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75

High crystallizability under air-exclusion conditions of the full-length LysR-type transcriptional regulator TsaR from Comamonas testosteroni T-2 and data-set analysis for a MIRAS structure-solution approach. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75

High speed X-ray analysis of plant enzymes at room temperature. Phytochemistry (2012) 0.75

The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity. Chemistry (2014) 0.75

Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours. J Enzyme Inhib Med Chem (2014) 0.75