Published in Circ Res on April 01, 2011
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Spontaneous diastolic contractions and phosphorylation of the cardiac ryanodine receptor at serine-2808 in congestive heart failure in rat. Cardiovasc Res (2005) 0.97
Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+. Biophys J (2007) 0.96
Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel. Biochemistry (2005) 0.96
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circ Res (2013) 0.92
Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors). J Biol Chem (2002) 0.91
Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardia. Channels (Austin) (2010) 0.89
In situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutation. Circ Arrhythm Electrophysiol (2012) 0.88
Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia. J Biol Chem (2008) 0.88
Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor. Biophys J (2009) 0.87
Ligand-dependent conformational changes in the clamp region of the cardiac ryanodine receptor. J Biol Chem (2012) 0.87
Role of CaMKII and ROS in rapid pacing-induced apoptosis. J Mol Cell Cardiol (2013) 0.87
The contribution of hydrophobic residues in the pore-forming region of the ryanodine receptor channel to block by large tetraalkylammonium cations and Shaker B inactivation peptides. J Gen Physiol (2012) 0.86
Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release. Biochem J (2013) 0.86
Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis. Circ Res (2014) 0.84
ARVC-related mutations in divergent region 3 alter functional properties of the cardiac ryanodine receptor. Biophys J (2008) 0.84
Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J (2002) 0.84
The CPVT-associated RyR2 mutation G230C enhances store overload-induced Ca2+ release and destabilizes the N-terminal domains. Biochem J (2013) 0.84
Calmodulin regulation of excitation-contraction coupling in cardiac myocytes. Circ Res (2003) 0.83
Reconstitution of local Ca2+ signaling between cardiac L-type Ca2+ channels and ryanodine receptors: insights into regulation by FKBP12.6. Am J Physiol Cell Physiol (2005) 0.82
Conformational dynamics inside amino-terminal disease hotspot of ryanodine receptor. Structure (2013) 0.82
Modeling a ryanodine receptor N-terminal domain connecting the central vestibule and the corner clamp region. J Biol Chem (2012) 0.82
Diffusion of single cardiac ryanodine receptors in lipid bilayers is decreased by annexin 12. Biophys J (2004) 0.82
Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations. Heart Rhythm (2012) 0.81
Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid. Mol Membr Biol (2007) 0.80
Two potential calmodulin-binding sequences in the ryanodine receptor contribute to a mobile, intra-subunit calmodulin-binding domain. J Cell Sci (2013) 0.79
The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors. FEBS Lett (2003) 0.79
The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance. Mol Pharmacol (2005) 0.79
The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice. Biochem J (2014) 0.77
Novel carvedilol analogues that suppress store-overload-induced Ca2+ release. J Med Chem (2013) 0.76