Published in Proc Natl Acad Sci U S A on April 11, 2011
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DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation. PLoS Biol (2004) 2.51
Mitotic remodeling of the replicon and chromosome structure. Cell (2005) 2.44
Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic Res (2001) 2.08
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation. Proc Natl Acad Sci U S A (2010) 2.01
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci U S A (2005) 1.91
Reversible disassembly of somatic nucleoli by the germ cell proteins FRGY2a and FRGY2b. Nat Cell Biol (2003) 1.86
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. J Neurochem (2003) 1.82
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A (2009) 1.71
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Active remodeling of somatic nuclei in egg cytoplasm by the nucleosomal ATPase ISWI. Science (2000) 1.64
DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J Biol Chem (2007) 1.59
p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J Neurochem (2006) 1.41
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Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic Res (2005) 1.27
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Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. J Biol Chem (2004) 1.20
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The cytoplasm of mouse germinal vesicle stage oocytes can enhance somatic cell nuclear reprogramming. Development (2008) 1.05
Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma. Int J Oncol (2011) 1.02
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Sumoylation is critical for DJ-1 to repress p53 transcriptional activity. FEBS Lett (2008) 0.92
DJ-1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc. FEBS Lett (2010) 0.88
Reversible membrane permeabilization of mammalian cells treated with digitonin and its use for inducing nuclear reprogramming by Xenopus egg extracts. Cloning Stem Cells (2008) 0.88
Somatic cell nuclear reprogramming of mouse oocytes endures beyond reproductive decline. Aging Cell (2010) 0.86
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Nuclear transfer and iPS may work best together. Cell Stem Cell (2008) 0.81
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Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep (2004) 3.84
Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem Biophys Res Commun (2004) 2.31
Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells. Nat Cell Biol (2007) 2.13
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells. Nat Genet (2007) 2.10
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun (2003) 1.96
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The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem (2001) 1.86
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease. J Biol Chem (2003) 1.78
Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression. Circ Res (2005) 1.76
Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells. Biochem Biophys Res Commun (2003) 1.69
DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. Mol Cancer Res (2003) 1.53
Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients. Biochem Biophys Res Commun (2004) 1.53
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol Dis (2006) 1.47
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Effect of hypothermia therapy after outpatient cardiac arrest due to ventricular fibrillation. Circ J (2009) 1.41
When does the sex ratio of offspring of the paternal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure decrease: in the spermatozoa stage or at fertilization? Reprod Toxicol (2009) 1.40
Equivalency of nuclear transfer-derived embryonic stem cells to those derived from fertilized mouse blastocysts. Stem Cells (2006) 1.39
DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3. Int J Oncol (2005) 1.39
Trypsinogen hL expressed in the human lung is a new member of the trypsinogen family. Biol Pharm Bull (2003) 1.37
Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. J Neurochem (2007) 1.34
The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes. Mol Cell Biol (2003) 1.32
A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus. J Biol Chem (2008) 1.32
Shematrin: a family of glycine-rich structural proteins in the shell of the pearl oyster Pinctada fucata. Comp Biochem Physiol B Biochem Mol Biol (2006) 1.29
Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic Res (2005) 1.27
Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases. Genetics (2013) 1.26
The origin of EFNB1 mutations in craniofrontonasal syndrome: frequent somatic mosaicism and explanation of the paucity of carrier males. Am J Hum Genet (2006) 1.22
Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway. Biochem Biophys Res Commun (2003) 1.17
Secretion of DJ-1 into the serum of patients with Parkinson's disease. Neurosci Lett (2007) 1.15
PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor. Exp Cell Res (2004) 1.15
Malignant phyllodes tumor of the prostate: retrospective review of specimens obtained by sequential transurethral resection. Pathol Int (2002) 1.14
Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice. Biochem Biophys Res Commun (2005) 1.13
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Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1. Biochem Biophys Res Commun (2005) 1.10
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. Int J Oncol (2009) 1.10
DJ-1 binds to mitochondrial complex I and maintains its activity. Biochem Biophys Res Commun (2009) 1.10
Modulation of collagen fibrillogenesis by tenascin-X and type VI collagen. Exp Cell Res (2004) 1.09
Reprogramming events of mammalian somatic cells induced by Xenopus laevis egg extracts. Mol Reprod Dev (2007) 1.08
A novel nacre protein N19 in the pearl oyster Pinctada fucata. Biochem Biophys Res Commun (2007) 1.08
A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome. J Biol Chem (2004) 1.07
Cell-free extracts from mammalian oocytes partially induce nuclear reprogramming in somatic cells. Biol Reprod (2009) 1.07
Arthroscopic, histological and MRI analyses of cartilage repair after a minimally invasive method of transplantation of allogeneic synovial mesenchymal stromal cells into cartilage defects in pigs. Cytotherapy (2012) 1.05
HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan. Clin Cancer Res (2006) 1.05
Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1. Toxicol Sci (2005) 1.05
DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J Cereb Blood Flow Metab (2007) 1.05
Loss of Rec8 from chromosome arm and centromere region is required for homologous chromosome separation and sister chromatid separation, respectively, in mammalian meiosis. Cell Cycle (2006) 1.05
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation. J Biol Chem (2012) 1.04
Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation. World J Gastroenterol (2012) 1.04
Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene. Exp Cell Res (2008) 1.04
Laparoscopic splenectomy for a huge splenic cyst without preoperative drainage: report of a case. Surg Laparosc Endosc Percutan Tech (2003) 1.03
Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. Biochem Biophys Res Commun (2002) 1.03
Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism. Acta Crystallogr D Biol Crystallogr (2003) 1.02
Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a. Cell Stem Cell (2012) 1.02
DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice. Biol Pharm Bull (2002) 1.02
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1. J Biol Chem (2009) 1.02
Atypical Bartter syndrome with sensorineural deafness with G47R mutation of the beta-subunit for ClC-Ka and ClC-Kb chloride channels, barttin. J Clin Endocrinol Metab (2003) 1.01
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Establishment of male and female nuclear transfer embryonic stem cell lines from different mouse strains and tissues. Biol Reprod (2004) 0.99
Longitudinal study for sleep-wake behaviours of mothers from pre-partum to post-partum using actigraph and sleep logs. Psychiatry Clin Neurosci (2002) 0.99
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Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxid Med Cell Longev (2010) 0.99
Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner. Mol Cell Biol (2012) 0.97
Identification, isolation, and in vitro culture of porcine gonocytes. Biol Reprod (2007) 0.96
DJ-1 interacts with HIPK1 and affects H2O2-induced cell death. Free Radic Res (2006) 0.96
DJ-1, a causative gene product of a familial form of Parkinson's disease, is secreted through microdomains. FEBS Lett (2008) 0.96
Dynamic rearrangement of telomeres during spermatogenesis in mice. Dev Biol (2005) 0.96
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Fatal retropharyngeal haematoma secondary to blunt trauma. Injury (2004) 0.95
Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway. Basic Clin Pharmacol Toxicol (2008) 0.95
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Acquisition of HIV-1 resistance in T lymphocytes using an ACA-specific E. coli mRNA interferase. Hum Gene Ther (2010) 0.95
Functional domains involved in the interaction between Orc1 and transcriptional repressor AlF-C that bind to an origin/promoter of the rat aldolase B gene. Nucleic Acids Res (2002) 0.95
Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis. PLoS One (2012) 0.94
The roles of vitamin A for cytoplasmic maturation of bovine oocytes. J Reprod Dev (2005) 0.94
AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors. Genes Cells (2006) 0.94
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Functional expression of a Delta12 fatty acid desaturase gene from spinach in transgenic pigs. Proc Natl Acad Sci U S A (2004) 0.94
Primary histiocytic sarcoma of the spleen associated with hemophagocytosis. Int J Hematol (2008) 0.94
Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos. Biol Reprod (2003) 0.93
Gene expression profiling of peripheral T-cell lymphoma including gammadelta T-cell lymphoma. Blood (2008) 0.93
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1. J Cell Sci (2013) 0.93
Specific cleavage of DJ-1 under an oxidative condition. Neurosci Lett (2006) 0.93