Published in Immune Netw on February 28, 2011
IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis. Semin Immunol (2012) 1.27
Transcriptional regulation of innate lymphoid cell fate. Nat Rev Immunol (2015) 1.21
Glut1-mediated glucose transport regulates HIV infection. Proc Natl Acad Sci U S A (2012) 1.02
Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development. Semin Immunol (2012) 0.97
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis. J Immunol (2012) 0.89
IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol (2013) 0.88
NF-κB signaling mediates homeostatic maturation of new T cells. Proc Natl Acad Sci U S A (2014) 0.84
The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes. Biochim Biophys Acta (2012) 0.80
CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1. J Biol Chem (2012) 0.78
Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function. BMC Biol (2014) 0.75
Establishment of IL-7 Expression Reporter Human Cell Lines, and Their Feasibility for High-Throughput Screening of IL-7-Upregulating Chemicals. PLoS One (2016) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol (2001) 31.56
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat Immunol (2000) 12.81
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol (2004) 10.60
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med (1994) 8.97
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med (1995) 7.52
Homeostasis of naive and memory T cells. Immunity (2008) 7.48
Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med (2002) 7.11
IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell (1993) 6.83
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature (2003) 6.78
Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol (2010) 6.02
New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol (2009) 5.57
Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature (1988) 5.50
Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat Immunol (2007) 5.22
Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol (2002) 4.36
Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet (1998) 4.32
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell (1997) 4.18
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med (2001) 3.69
Suppression of IL7Ralpha transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity (2004) 3.67
The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J Immunol (2005) 3.51
Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells. Immunity (2005) 3.39
IL-7 enhances the survival and maintains the size of naive T cells. J Immunol (2001) 3.39
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature (1994) 3.36
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell (1997) 3.13
Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells. J Exp Med (2002) 3.06
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. Nat Immunol (2007) 2.80
Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol (2001) 2.65
B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors. J Exp Med (1988) 2.64
Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. Proc Natl Acad Sci U S A (1989) 2.46
Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev (2005) 2.35
Hepatic interleukin-7 expression regulates T cell responses. Immunity (2009) 2.25
IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. Blood (2007) 2.24
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat Immunol (2010) 2.19
Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes. J Clin Invest (1995) 2.16
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol (2009) 1.98
T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo. Int Immunol (2001) 1.82
Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity (2007) 1.79
Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood (2007) 1.34
Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements. Immunity (2003) 1.31
Characterization of the thymic IL-7 niche in vivo. Proc Natl Acad Sci U S A (2009) 1.27
Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice. J Immunol (1993) 1.25
Interleukin 7 is produced by murine and human keratinocytes. J Exp Med (1993) 1.22
Ontogeny and regulation of IL-7-expressing thymic epithelial cells. J Immunol (2005) 1.16
Cytokine-driven cell cycling is mediated through Cdc25A. J Cell Biol (2005) 1.15
Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. Mol Cell Biol (2004) 1.15
Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo. Eur J Immunol (2010) 1.14
IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells. Genesis (2009) 1.12
The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice. J Exp Med (1996) 1.11
Visualization and identification of IL-7 producing cells in reporter mice. PLoS One (2009) 1.11
Cytokine signals in T-cell homeostasis. J Immunother (2005) 1.07
Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression. Blood (2003) 1.06
The IL-7 signaling pathway regulates lymph node development independent of peripheral lymphocytes. J Immunol (2010) 1.04
Characterization of B lymphocyte lineage progenitor cells from mice with severe combined immune deficiency disease (SCID) made possible by long term culture. J Immunol (1987) 1.03
The lack of epithelial interleukin-7 and BAFF/BLyS gene expression in prostate cancer as a possible mechanism of tumor escape from immunosurveillance. Clin Cancer Res (2009) 0.97
Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II gene. Am J Physiol Cell Physiol (2010) 0.92
Cutting Edge: a thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo. J Immunol (2010) 0.90
Expression of interleukin 7 (IL-7) mRNA and protein in the normal adult human liver: implications for extrathymic T cell development. Cytokine (2001) 0.88
Studies on the role of IL-7 presentation by mesenchymal fibroblasts during early thymocyte development. Eur J Immunol (2000) 0.88
Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells. Genes Immun (2009) 0.85
Cutting edge: Identification of a hybrid cytokine consisting of IL-7 and the beta-chain of the hepatocyte growth factor/scatter factor. J Immunol (2001) 0.83
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice. Nat Rev Immunol (2008) 2.98
Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC. Immunity (2007) 2.66
IL-7 signaling must be intermittent, not continuous, during CD8⁺ T cell homeostasis to promote cell survival instead of cell death. Nat Immunol (2012) 1.93
IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development. J Exp Med (2004) 1.52
CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, type I IFN, and IL-7. J Immunol (2011) 1.37
αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities. Immunity (2011) 1.33
Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection. J Exp Med (2006) 1.32
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection. Nat Immunol (2012) 1.28
Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin. Lung Cancer (2007) 1.24
The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. Immunity (2012) 1.19
Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells. Mol Cancer Ther (2006) 1.18
Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. Cancer Res (2008) 1.11
Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model. J Allergy Clin Immunol (2004) 1.08
The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. Mol Biol Cell (2005) 1.04
Multicomponent approach to the synthesis of oxidized amides through nitrile hydrozirconation. Org Lett (2007) 1.03
Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. J Mol Med (Berl) (2007) 1.03
Coxsackievirus B3 infection induces cyr61 activation via JNK to mediate cell death. J Virol (2004) 1.00
Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus. J Exp Med (2012) 0.99
Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression. Biochem Biophys Res Commun (2007) 0.97
Inhibition of histone deacetylase 10 induces thioredoxin-interacting protein and causes accumulation of reactive oxygen species in SNU-620 human gastric cancer cells. Mol Cells (2010) 0.97
Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development. Semin Immunol (2012) 0.97
Mitogenic signals through CD28 activate the protein kinase Ctheta-NF-kappaB pathway in primary peripheral T cells. Int Immunol (2003) 0.96
Leptin receptor isoform expression in rat osteoblasts and their functional analysis. FEBS Lett (2002) 0.95
Respiratory muscle strength and cough capacity in patients with Duchenne muscular dystrophy. Yonsei Med J (2006) 0.95
Ginsenoside composition and antiproliferative activities of explosively puffed ginseng (Panax ginseng C.A. Meyer). J Food Sci (2010) 0.94
Multicomponent synthesis of alpha-branched amides. Org Lett (2009) 0.94
Map-based cloning of the ERECT PANICLE 3 gene in rice. Theor Appl Genet (2009) 0.92
An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis. J Immunol (2012) 0.89
Significance of aortic atherosclerotic disease in possibly embolic stroke: 64-multidetector row computed tomography study. J Neurol (2009) 0.87
NKT cell-dependent regulation of secondary antigen-specific, conventional CD4+ T cell immune responses. J Immunol (2010) 0.86
Clinical analysis of living donor liver transplantation in patients with portal vein thrombosis. Clin Transplant (2011) 0.86
Coreceptor gene imprinting governs thymocyte lineage fate. EMBO J (2011) 0.86
Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus. Blood (2013) 0.84
Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. J Immunol (2008) 0.84
A-kinase anchoring protein 12 regulates the completion of cytokinesis. Biochem Biophys Res Commun (2008) 0.83
HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127. AIDS (2013) 0.83
Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116. Hypertension (2010) 0.83
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors. J Med Chem (2003) 0.82
Role of cardiac multidetector computed tomography in acute ischemic stroke: a preliminary report. Cerebrovasc Dis (2010) 0.82
Anti-tumor immunostimulatory effect of heat-killed tumor cells. Exp Mol Med (2008) 0.82
Antioxidative and cytoprotective effects of Artemisia capillaris fractions. Biofactors (2007) 0.82
Natural killer T cells promote collagen-induced arthritis in DBA/1 mice. Biochem Biophys Res Commun (2009) 0.81
A novel ginseng saponin metabolite induces apoptosis and down-regulates fibroblast growth factor receptor 3 in myeloma cells. Int J Oncol (2003) 0.81
Troglitazone, a thiazolidinedione, decreases tau phosphorylation through the inhibition of cyclin-dependent kinase 5 activity in SH-SY5Y neuroblastoma cells and primary neurons. J Neurochem (2013) 0.81
DNA methyltransferase 3B acts as a co-repressor of the human polycomb protein hPc2 to repress fibroblast growth factor receptor 3 transcription. Int J Biochem Cell Biol (2008) 0.81
Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination. Proc Natl Acad Sci U S A (2013) 0.81
The presence of CD8+ invariant NKT cells in mice. Exp Mol Med (2009) 0.80
Antitumor activity of SK-7041, a novel histone deacetylase inhibitor, in human lung and breast cancer cells. Anticancer Res (2006) 0.80
A new reporter vector system based on flow-cytometry to detect promoter activity. Immune Netw (2009) 0.80
Fluorescence polarization immunoassay based on a monoclonal antibody for the detection of the organophosphorus pesticide parathion-methyl. J Agric Food Chem (2003) 0.80
Genetic variation of 23 autosomal STR loci in Korean population. Forensic Sci Int Genet (2013) 0.80
Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling. Eur J Immunol (2013) 0.79
CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1. J Biol Chem (2012) 0.78
Molecular tripods showing fluorescence enhancement upon binding to streptavidin. Org Lett (2005) 0.78
Interleukin-6 expands homeostatic space for peripheral T cells. Cytokine (2013) 0.77
Radical scavenging-linked antioxidant activities of commonly used herbs and spices in Korea. Int J Food Sci Nutr (2011) 0.77
Coreceptor gene "imprinting:" a genetic solution to a developmental dilemma in T cells. Cell Cycle (2012) 0.77
A mechanism of immunoreceptor tyrosine-based activation motif (ITAM)-like sequences in the capsid protein VP2 in viral growth and pathogenesis of Coxsackievirus B3. Virus Genes (2011) 0.76
Hepatic artery reconstruction and successful management of its complications in living donor liver transplantation using a right lobe. Clin Transplant (2011) 0.76
γc Cytokine signaling: graduate school in thymic education. Blood (2013) 0.76
Therapeutic effects of Chiljehyangbuhwan on primary dysmenorrhea: a randomized, double blind, placebo-controlled study. Complement Ther Med (2008) 0.75
Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells. Int J Biochem Cell Biol (2008) 0.75
Clinical analysis of emergency liver transplantation: the role of living donor liver transplantation. Clin Transplant (2012) 0.75
Epidermal growth factor-like domain 8 inhibits the survival and proliferation of mouse thymocytes. Int J Mol Med (2013) 0.75
New insights into ETS-10 and titanate quantum wire: a comprehensive characterization. J Am Chem Soc (2009) 0.75