Dietary intakes of arachidonic acid and alpha-linolenic acid are associated with reduced risk of hip fracture in older adults.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMC 3095142)

Published in J Nutr on April 20, 2011

Authors

Emily K Farina1, Douglas P Kiel, Ronenn Roubenoff, Ernst J Schaefer, L Adrienne Cupples, Katherine L Tucker

Author Affiliations

1: Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.

Articles citing this

Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures. J Bone Miner Res (2013) 1.96

Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids. PLoS One (2012) 1.03

Marrow fat composition in anorexia nervosa. Bone (2014) 1.01

An investigation of the association between omega 3 FA and bone mineral density among older adults: results from the National Health and Nutrition Examination Survey years 2005–2008. Osteoporos Int (2014) 0.88

Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women. Osteoporos Int (2012) 0.88

The association of red blood cell n-3 and n-6 fatty acids with bone mineral density and hip fracture risk in the women's health initiative. J Bone Miner Res (2013) 0.88

Plasma phosphatidylcholine concentrations of polyunsaturated fatty acids are differentially associated with hip bone mineral density and hip fracture in older adults: the Framingham Osteoporosis Study. J Bone Miner Res (2012) 0.86

VITAL-Bone Health: rationale and design of two ancillary studies evaluating the effects of vitamin D and/or omega-3 fatty acid supplements on incident fractures and bone health outcomes in the VITamin D and OmegA-3 TriaL (VITAL). Contemp Clin Trials (2015) 0.85

Polyunsaturated fatty acids and their relation with bone and muscle health in adults. Curr Osteoporos Rep (2013) 0.84

Arachidonic acid and docosahexaenoic acid suppress osteoclast formation and activity in human CD14+ monocytes, in vitro. PLoS One (2015) 0.82

Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study. Am J Clin Nutr (2015) 0.81

A systematic review of omega-3 fatty acids and osteoporosis. Br J Nutr (2012) 0.81

Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study. Curr Osteoporos Rep (2015) 0.80

Effects of ω3- and ω6-polyunsaturated fatty acids on RANKL-induced osteoclast differentiation of RAW264.7 cells: a comparative in vitro study. Nutrients (2014) 0.80

Diet and gene interactions influence the skeletal response to polyunsaturated fatty acids. Bone (2014) 0.80

Assessment of bone turnover and bone quality in type 2 diabetic bone disease: current concepts and future directions. Bone Res (2016) 0.79

TNF Receptors Predict Hip Fracture Risk in the WHI Study and Fatty Acid Intake Does Not Modify This Association. J Clin Endocrinol Metab (2015) 0.78

Characterization of Fatty Acid Composition in Bone Marrow Fluid From Postmenopausal Women: Modification After Hip Fracture. J Cell Biochem (2016) 0.77

Canola oil consumption and bone health. J Res Med Sci (2012) 0.75

The Association between the Consumption of Fish/Shellfish and the Risk of Osteoporosis in Men and Postmenopausal Women Aged 50 Years or Older. Nutrients (2016) 0.75

Polyunsaturated fatty acids and calcaneal ultrasound parameters among Inuit women from Nuuk (Greenland): a longitudinal study. Int J Circumpolar Health (2013) 0.75

Whole Blood Levels of the n-6 Essential Fatty Acid Linoleic Acid Are Inversely Associated with Stunting in 2-to-6 Year Old Tanzanian Children: A Cross-Sectional Study. PLoS One (2016) 0.75

Articles cited by this

Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol (1985) 26.13

Epidemiological approaches to heart disease: the Framingham Study. Am J Public Health Nations Health (1951) 20.27

Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. Am J Epidemiol (1992) 17.17

Adjustment for total energy intake in epidemiologic studies. Am J Clin Nutr (1997) 11.07

PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell (1999) 9.74

Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation (2002) 9.02

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med (2002) 7.99

The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med (1989) 5.02

Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol (1997) 4.71

Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem (1999) 3.57

Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res (2000) 3.09

Does body mass index adequately capture the relation of body composition and body size to health outcomes? Am J Epidemiol (1998) 3.07

Hip fracture and the use of estrogens in postmenopausal women. The Framingham Study. N Engl J Med (1987) 3.00

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol (2006) 2.98

Comparison of measures of fatty acid intake by subcutaneous fat aspirate, food frequency questionnaire, and diet records in a free-living population of US men. Am J Epidemiol (1992) 2.68

Estrogen replacement therapy and fractures in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med (1995) 2.58

RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis. FASEB J (2005) 2.47

Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient status. Am J Clin Nutr (1993) 2.44

Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr (1999) 1.99

Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study. Hum Mol Genet (2000) 1.94

The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr (1996) 1.86

n-3 Fatty acids are positively associated with peak bone mineral density and bone accrual in healthy men: the NO2 Study. Am J Clin Nutr (2007) 1.85

Fatty acid modulation of endothelial activation. Am J Clin Nutr (2000) 1.81

Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women. J Nutr (1991) 1.57

Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: the Rancho Bernardo Study. Am J Clin Nutr (2005) 1.41

Metabolism of alpha-linolenic acid in humans. Prostaglandins Leukot Essent Fatty Acids (2006) 1.39

Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized mice. J Bone Miner Res (2003) 1.38

Bone mineral density in elderly men and women: results from the Framingham osteoporosis study. J Bone Miner Res (1992) 1.34

Dietary saturated fat intake is inversely associated with bone density in humans: analysis of NHANES III. J Nutr (2006) 1.34

Who has osteoporosis? A conflict between clinical and public health perspectives. J Bone Miner Res (2000) 1.30

Vitamin K intake and bone mineral density in women and men. Am J Clin Nutr (2003) 1.30

Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis. Aging (Milano) (1998) 1.26

Dietary ratio of (n-6)/(n-3) polyunsaturated fatty acids alters the fatty acid composition of bone compartments and biomarkers of bone formation in rats. J Nutr (2000) 1.24

Dietary ratio of n-6/n-3 PUFAs and docosahexaenoic acid: actions on bone mineral and serum biomarkers in ovariectomized rats. J Nutr Biochem (2005) 1.23

A systematic review of the impact of n-3 fatty acids in bone health and osteoporosis. Med Sci Monit (2008) 1.23

Dose response of bone mass to dietary arachidonic acid in piglets fed cow milk-based formula. Am J Clin Nutr (2004) 1.21

Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study. Am J Clin Nutr (2008) 1.16

Fatty acid consumption and risk of fracture in the Women's Health Initiative. Am J Clin Nutr (2010) 1.16

An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans. Nutr J (2007) 1.14

Modulatory effect of omega-3 polyunsaturated fatty acids on osteoblast function and bone metabolism. Prostaglandins Leukot Essent Fatty Acids (2003) 1.13

An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption. Br J Pharmacol (2008) 1.13

Self-reported dietary intake of omega-3 fatty acids and association with bone and lower extremity function. J Am Geriatr Soc (2009) 1.11

The effect of n-3 fatty acids on bone biomarkers in Iranian postmenopausal osteoporotic women: a randomized clinical trial. Age (Dordr) (2009) 1.11

Fish consumption, bone mineral density, and risk of hip fracture among older adults: the cardiovascular health study. J Bone Miner Res (2010) 1.10

DNA binding-independent induction of IkappaBalpha gene transcription by PPARalpha. Mol Endocrinol (2002) 1.07

Long-chain polyunsaturated fatty acids: selected mechanisms of action on bone. Prog Lipid Res (2010) 1.05

Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment. J Clin Invest (1993) 1.02

Capacity of omega-3 fatty acids or eicosapentaenoic acid to counteract weightlessness-induced bone loss by inhibiting NF-kappaB activation: from cells to bed rest to astronauts. J Bone Miner Res (2010) 1.02

Can manipulation of the ratios of essential fatty acids slow the rapid rate of postmenopausal bone loss? Altern Med Rev (2001) 1.01

Bioactive fatty acids: role in bone biology and bone cell function. Prog Lipid Res (2001) 1.00

Endogenous n-3 fatty acids protect ovariectomy induced bone loss by attenuating osteoclastogenesis. J Cell Mol Med (2009) 0.99

Dietary fat intake and the risk of osteoporotic fractures in the elderly. Eur J Clin Nutr (2007) 0.99

Protective effect of dietary long-chain n-3 polyunsaturated fatty acids on bone loss in gonad-intact middle-aged male rats. Br J Nutr (2006) 0.97

Bone mineral content is positively correlated to n-3 fatty acids in the femur of growing rats. Br J Nutr (2010) 0.97

Energy intake and monounsaturated fat in relation to bone mineral density among women and men in Greece. Prev Med (1997) 0.96

Repletion with (n-3) fatty acids reverses bone structural deficits in (n-3)-deficient rats. J Nutr (2004) 0.95

Polyunsaturated fatty acids. Is there a role in postmenopausal osteoporosis prevention? Maturitas (2002) 0.92

Validity of estimated dietary eicosapentaenoic acid and docosahexaenoic acid intakes determined by interviewer-administered food frequency questionnaire among older adults with mild-to-moderate cognitive impairment or dementia. Am J Epidemiol (2009) 0.92

Plasma phospholipid arachidonic acid content and calcium metabolism in idiopathic calcium nephrolithiasis. Kidney Int (2000) 0.89

Nutraceutical fatty acids as biochemical and molecular modulators of skeletal biology. J Am Coll Nutr (2001) 0.88

Improvement of bone formation biomarkers after 1-year consumption with milk fortified with eicosapentaenoic acid, docosahexaenoic acid, oleic acid, and selected vitamins. Nutr Res (2010) 0.88

Calcium transport by isolated brush border and basolateral membrane vesicles: role of essential fatty acid supplementation. Prostaglandins Leukot Essent Fatty Acids (1994) 0.87

Oestrogen and essential fatty acid supplementation corrects bone loss due to ovariectomy in the female Sprague Dawley rat. Prostaglandins Leukot Essent Fatty Acids (1999) 0.86

Dietary fish oil results in a greater bone mass and bone formation indices in aged ovariectomized rats. J Bone Miner Metab (2008) 0.86

A longitudinal study of nonvitamin, nonmineral supplement use: prevalence, associations, and survival in an aging population. Ann Epidemiol (2007) 0.86

Polyunsaturated fatty acids, inflammation, and cardiovascular disease: time to widen our view of the mechanisms. J Clin Endocrinol Metab (2006) 0.86

Inhibition of osteoporosis due to restricted food intake by the fish oils DHA and EPA and perilla oil in the rat. Biosci Biotechnol Biochem (2004) 0.86

Maternal and cord blood long-chain polyunsaturated fatty acids are predictive of bone mass at birth in healthy term-born infants. Pediatr Res (2005) 0.85

Prostaglandin D2 metabolite stimulates collagen synthesis by human osteoblasts during calcification. Prostaglandins (1991) 0.84

Dietary supplementation of arachidonic acid is associated with higher whole body weight and bone mineral density in growing pigs. Pediatr Res (2000) 0.84

Enhancement of in vitro mineralization in human osteoblasts by a novel prostaglandin A1 derivative TEI-3313. J Pharmacol Exp Ther (1991) 0.80

Flaxseed does not antagonize the effect of ultra-low-dose estrogen therapy on bone mineral density and biomechanical bone strength in ovariectomized rats. J Toxicol Environ Health A (2009) 0.77

Docosahexaenoic acid and 17 beta-estradiol co-treatment is more effective than 17 beta-estradiol alone in maintaining bone post-ovariectomy. Exp Biol Med (Maywood) (2008) 0.77

Articles by these authors

Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66

Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25

Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80

Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med (2008) 9.68

Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA (2005) 9.61

Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest (2009) 7.09

Clinical utility of different lipid measures for prediction of coronary heart disease in men and women. JAMA (2007) 6.95

Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med (2009) 6.43

Unique lipoprotein phenotype and genotype associated with exceptional longevity. JAMA (2003) 6.17

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med Genet (2007) 5.64

Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med (2009) 5.63

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32

Empirically derived eating patterns using factor or cluster analysis: a review. Nutr Rev (2004) 5.18

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02

The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc (2004) 4.84

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. PLoS Genet (2009) 4.71

Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med (2004) 4.34

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28

Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation (2006) 4.25

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes (2008) 4.20

Chronic musculoskeletal pain and the occurrence of falls in an older population. JAMA (2009) 4.18

Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation (2003) 4.09

Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet (2002) 4.07

Approaching health disparities from a population perspective: the National Institutes of Health Centers for Population Health and Health Disparities. Am J Public Health (2008) 3.98

Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA (2009) 3.62

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55

Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med (2004) 3.49

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol (2004) 3.33

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet (2009) 3.18

Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA (2002) 3.16

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15

Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. Am J Clin Nutr (2007) 3.14

The landscape of recombination in African Americans. Nature (2011) 3.06

Genetic associations with valvular calcification and aortic stenosis. N Engl J Med (2013) 3.02

Comparison of the effect of denosumab and alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a randomized, blinded, phase 3 trial. J Bone Miner Res (2009) 2.99

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol (2006) 2.98

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet (2007) 2.93

Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91

Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet (2010) 2.91

A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes Care (2002) 2.91

The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci (2014) 2.84

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80

Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch Ophthalmol (2010) 2.78

FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73

CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. PLoS One (2013) 2.65

Tai Chi is effective in treating knee osteoarthritis: a randomized controlled trial. Arthritis Rheum (2009) 2.63

Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet (2013) 2.62

Value of high-density lipoprotein (HDL) subpopulations in predicting recurrent cardiovascular events in the Veterans Affairs HDL Intervention Trial. Arterioscler Thromb Vasc Biol (2005) 2.61

A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes (2007) 2.60

Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT). Arch Intern Med (2002) 2.59

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet (2009) 2.58

Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet (2010) 2.57

Depression as a risk factor for Alzheimer disease: the MIRAGE Study. Arch Neurol (2003) 2.56

Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis. J Natl Cancer Inst (2005) 2.54

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA (2008) 2.52

Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr (2002) 2.47

Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial. Genet Med (2004) 2.44

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43

The MOBILIZE Boston Study: design and methods of a prospective cohort study of novel risk factors for falls in an older population. BMC Geriatr (2008) 2.42

Dietary patterns and adenocarcinoma of the esophagus and distal stomach. Am J Clin Nutr (2002) 2.40

Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study. J Am Soc Nephrol (2004) 2.36

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. Circulation (2004) 2.35

Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc (2011) 2.34

HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. Clin Chem (2011) 2.33

Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study. BMJ (2012) 2.32

Dietary patterns and changes in body mass index and waist circumference in adults. Am J Clin Nutr (2003) 2.30

Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study. Alzheimer Dis Assoc Disord (2008) 2.30

Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort. Am J Clin Nutr (2002) 2.29

Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans. J Clin Invest (2003) 2.27

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet (2007) 2.25

Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation (2008) 2.22