Published in Curr Biol on May 12, 2011
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Molecular control of animal cell cytokinesis. Nat Cell Biol (2012) 2.45
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα. J Cell Biol (2012) 1.94
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Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. Dev Cell (2012) 1.24
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Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol (2013) 1.13
Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis. J Cell Biol (2012) 1.10
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Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Mol Biol Cell (2012) 1.05
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The kinesin-8 Kip3 scales anaphase spindle length by suppression of midzone microtubule polymerization. J Cell Biol (2014) 0.82
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Microtubule networks for plant cell division. Syst Synth Biol (2014) 0.77
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Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission. Mol Biol Cell (2016) 0.75
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Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. Sci Rep (2017) 0.75
Motor activity of centromere-associated protein-E contributes to its localization at the center of the midbody to regulate cytokinetic abscission. Oncotarget (2016) 0.75
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Interdependency and phosphorylation of KIF4 and condensin I are essential for organization of chromosome scaffold. PLoS One (2017) 0.75
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PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone. J Cell Biol (2002) 3.51
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Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis. Proc Natl Acad Sci U S A (2004) 2.29
Cell-size-dependent spindle elongation in the Caenorhabditis elegans early embryo. Curr Biol (2009) 2.14
Kif15 cooperates with eg5 to promote bipolar spindle assembly. Curr Biol (2009) 2.10
S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression. J Biol Chem (2006) 2.09
KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol (2006) 2.06
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Human chromokinesin KIF4A functions in chromosome condensation and segregation. J Cell Biol (2004) 1.81
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Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation. Dev Cell (2009) 1.58
A kinesin-like motor inhibits microtubule dynamic instability. Science (2004) 1.57
Ablation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does not. Mol Biol Cell (2004) 1.56
Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One (2007) 1.53
Stabilization of overlapping microtubules by fission yeast CLASP. Dev Cell (2007) 1.50
Rho-kinase controls cell shape changes during cytokinesis. Curr Biol (2006) 1.42
Chromokinesins: multitalented players in mitosis. Trends Cell Biol (2005) 1.41
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Midzone organization restricts interpolar microtubule plus-end dynamics during spindle elongation. EMBO Rep (2009) 1.07
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Mechanical and genetic separation of aster- and midzone-positioned cytokinesis. Biochem Soc Trans (2008) 0.84
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Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol (2005) 11.63
A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A (2008) 10.09
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature (2009) 5.55
Multidimensional drug profiling by automated microscopy. Science (2004) 5.45
Self- and actin-templated assembly of Mammalian septins. Dev Cell (2002) 4.48
A standardized kinesin nomenclature. J Cell Biol (2004) 4.43
Reassembly of contractile actin cortex in cell blebs. J Cell Biol (2006) 4.31
Single-molecule speckle analysis of actin filament turnover in lamellipodia. Science (2002) 4.27
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Membrane proteins of the endoplasmic reticulum induce high-curvature tubules. Science (2008) 3.60
Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell (2004) 3.51
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell (2009) 3.44
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol (2004) 3.39
Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell (2013) 3.26
Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nat Chem Biol (2007) 3.17
Poly(ADP-ribose) is required for spindle assembly and structure. Nature (2004) 3.11
Life and times of a cellular bleb. Biophys J (2007) 3.05
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. J Cell Biol (2003) 3.01
EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules. Mol Biol Cell (2002) 2.92
Determining the position of the cell division plane. Nature (2003) 2.80
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol (2005) 2.70
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation. Mol Biol Cell (2004) 2.51
Structural plasticity in actin and tubulin polymer dynamics. Science (2009) 2.45
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (2011) 2.44
Anillin binds nonmuscle myosin II and regulates the contractile ring. Mol Biol Cell (2004) 2.33
Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton. Chem Biol (2002) 2.28
EB1 targets to kinetochores with attached, polymerizing microtubules. Mol Biol Cell (2002) 2.27
Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Curr Biol (2002) 2.27
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A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. BMC Biotechnol (2004) 2.08
Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality. Proc Natl Acad Sci U S A (2004) 2.08
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1. J Cell Biol (2006) 2.07
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. J Cell Biol (2004) 2.06
A quantitative analysis of contractility in active cytoskeletal protein networks. Biophys J (2008) 2.05
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Evidence for an upper limit to mitotic spindle length. Curr Biol (2008) 1.94
Cell polarization during monopolar cytokinesis. J Cell Biol (2008) 1.92
Small molecule screening by imaging. Curr Opin Chem Biol (2006) 1.90
Structural insights into yeast septin organization from polarized fluorescence microscopy. Nature (2006) 1.83
Slide-and-cluster models for spindle assembly. Curr Biol (2007) 1.79
An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin. Dev Cell (2003) 1.76
A model for cleavage plane determination in early amphibian and fish embryos. Curr Biol (2010) 1.72
Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Curr Biol (2007) 1.69
A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii. Proc Natl Acad Sci U S A (2004) 1.64
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Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chem Biol (2002) 1.58
XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol (2004) 1.56
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Mol Biol Cell (2011) 1.53
Noble metals strip peptides from class II MHC proteins. Nat Chem Biol (2006) 1.53
Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther (2008) 1.53
Midbody assembly and its regulation during cytokinesis. Mol Biol Cell (2012) 1.50
Dynamic stabilization of actin filaments. Proc Natl Acad Sci U S A (2008) 1.50
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The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. Curr Biol (2002) 1.46
A new method reveals microtubule minus ends throughout the meiotic spindle. J Cell Biol (2006) 1.46
Microtubule plus-end dynamics in Xenopus egg extract spindles. Mol Biol Cell (2004) 1.45
Compression regulates mitotic spindle length by a mechanochemical switch at the poles. Curr Biol (2009) 1.44
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Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor. Chem Biol (2005) 1.43
Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb. Biochemistry (2004) 1.40
High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem (2005) 1.38
Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity. Development (2005) 1.37
Nuf, a Rab11 effector, maintains cytokinetic furrow integrity by promoting local actin polymerization. J Cell Biol (2008) 1.37
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Deformations within moving kinetochores reveal different sites of active and passive force generation. Science (2012) 1.36
The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J Biol Chem (2003) 1.29
Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest. PLoS One (2010) 1.28
Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Cancer Res (2011) 1.27
Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Curr Biol (2009) 1.27
A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes. Curr Biol (2005) 1.26
Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly. Mol Biol Cell (2009) 1.20
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Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol. BMC Chem Biol (2006) 1.19
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Curr Biol (2009) 1.19
Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Curr Biol (2004) 1.19
Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Mol Cell Proteomics (2009) 1.18
Mammalian septins nomenclature. Mol Biol Cell (2002) 1.16
Clues to CD2-associated protein involvement in cytokinesis. Mol Biol Cell (2005) 1.16
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci (2008) 1.15