Published in Annu Rev Biochem on January 01, 2006
Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell (2008) 3.26
The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat Rev Mol Cell Biol (2009) 2.88
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol (2011) 2.65
Mechanics of cytokinesis in eukaryotes. Curr Opin Cell Biol (2009) 2.65
Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. Proc Natl Acad Sci U S A (2011) 2.45
Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release. Proc Natl Acad Sci U S A (2008) 2.33
Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion. Traffic (2008) 2.16
A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol (2009) 2.04
Whole chromosome instability and cancer: a complex relationship. Trends Genet (2008) 2.04
Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells. J Cell Biol (2008) 2.02
Cell polarization during monopolar cytokinesis. J Cell Biol (2008) 1.92
A secreted protein promotes cleavage furrow maturation during cytokinesis. Curr Biol (2011) 1.88
Marking and measuring single microtubules by PRC1 and kinesin-4. Cell (2013) 1.86
Dividing cells regulate their lipid composition and localization. Cell (2014) 1.84
Kinesins and cancer. Nat Rev Cancer (2012) 1.84
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS Biol (2009) 1.78
Polar actomyosin contractility destabilizes the position of the cytokinetic furrow. Nature (2011) 1.78
mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells. Mol Biol Cell (2008) 1.78
A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytes. Curr Biol (2008) 1.75
A model for cleavage plane determination in early amphibian and fish embryos. Curr Biol (2010) 1.72
Midbody ring disposal by autophagy is a post-abscission event of cytokinesis. Nat Cell Biol (2008) 1.70
Essential role of hIST1 in cytokinesis. Mol Biol Cell (2009) 1.62
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol (2010) 1.60
Membrane-induced bundling of actin filaments. Nat Phys (2008) 1.58
Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission. J Cell Biol (2010) 1.55
Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One (2007) 1.53
No strings attached: the ESCRT machinery in viral budding and cytokinesis. J Cell Sci (2009) 1.50
Cell polarization and cytokinesis in budding yeast. Genetics (2012) 1.45
An equatorial contractile mechanism drives cell elongation but not cell division. PLoS Biol (2014) 1.45
Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression. Dev Cell (2012) 1.43
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo. PLoS Genet (2015) 1.43
When 2+2=5: the origins and fates of aneuploid and tetraploid cells. Biochim Biophys Acta (2008) 1.42
Rho-dependent control of anillin behavior during cytokinesis. J Cell Biol (2008) 1.42
Specificity of cytoplasmic dynein subunits in discrete membrane-trafficking steps. Mol Biol Cell (2009) 1.39
FIP3-endosome-dependent formation of the secondary ingression mediates ESCRT-III recruitment during cytokinesis. Nat Cell Biol (2012) 1.38
Planar spindle orientation and asymmetric cytokinesis in the mouse small intestine. J Histochem Cytochem (2007) 1.37
The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents. J Clin Invest (2009) 1.36
Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. J Cell Biol (2008) 1.33
Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission. J Cell Sci (2011) 1.29
Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei. PLoS One (2008) 1.26
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. J Cell Biol (2011) 1.26
How unfinished business from S-phase affects mitosis and beyond. EMBO J (2013) 1.26
Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis. J Cell Biol (2009) 1.23
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. J Biol Chem (2011) 1.23
Erythroblast enucleation. Stem Cells Int (2011) 1.21
Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission. Nat Rev Mol Cell Biol (2012) 1.21
Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol (2010) 1.19
Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle. J Cell Biol (2008) 1.19
Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Mol Cell Proteomics (2009) 1.18
The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis. Open Biol (2012) 1.17
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17
Polarity in stem cell division: asymmetric stem cell division in tissue homeostasis. Cold Spring Harb Perspect Biol (2010) 1.17
Furrow constriction in animal cell cytokinesis. Biophys J (2014) 1.15
14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis. Curr Biol (2010) 1.14
Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol (2013) 1.13
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
Stabilization of the actomyosin ring enables spermatocyte cytokinesis in Drosophila. Mol Biol Cell (2010) 1.11
Membrane dynamics during cytokinesis. Curr Opin Cell Biol (2012) 1.11
Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules. Mol Biol Cell (2009) 1.11
Making the cut: the chemical biology of cytokinesis. ACS Chem Biol (2010) 1.09
Proper organization of microtubule minus ends is needed for midzone stability and cytokinesis. Curr Biol (2010) 1.08
Mitotic spindle proteomics in Chinese hamster ovary cells. PLoS One (2011) 1.08
Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells. J Cell Biol (2009) 1.08
Making the final cut - mechanisms mediating the abscission step of cytokinesis. ScientificWorldJournal (2010) 1.07
Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos. J Cell Sci (2011) 1.07
Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis. Cell Cycle (2012) 1.06
Understanding cytokinesis failure. Adv Exp Med Biol (2010) 1.06
Cytokinesis through biochemical-mechanical feedback loops. Semin Cell Dev Biol (2010) 1.06
An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins. Proc Natl Acad Sci U S A (2011) 1.05
Dividing the spoils of growth and the cell cycle: The fission yeast as a model for the study of cytokinesis. Cytoskeleton (Hoboken) (2011) 1.05
Binucleine 2, an isoform-specific inhibitor of Drosophila Aurora B kinase, provides insights into the mechanism of cytokinesis. ACS Chem Biol (2010) 1.05
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Mol Biol Cell (2012) 1.05
Computational model of cytokinetic abscission driven by ESCRT-III polymerization and remodeling. Biophys J (2012) 1.04
Anillin acts as a bifunctional linker coordinating midbody ring biogenesis during cytokinesis. Curr Biol (2012) 1.04
Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle. Mol Biol Cell (2009) 1.04
Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif (2008) 1.04
Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression. PLoS Comput Biol (2012) 1.04
The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1. Nucleus (2011) 1.03
Modeling structure-function relationships in synthetic DNA sequences using attribute grammars. PLoS Comput Biol (2009) 1.03
Anillin-mediated targeting of peanut to pseudocleavage furrows is regulated by the GTPase Ran. Mol Biol Cell (2008) 1.03
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development. Commun Integr Biol (2011) 1.03
Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells. Cytoskeleton (Hoboken) (2012) 1.02
Inhibition of glycosphingolipid biosynthesis induces cytokinesis failure. J Am Chem Soc (2011) 1.01
G protein-coupled receptors participate in cytokinesis. Cytoskeleton (Hoboken) (2012) 1.01
Redundant mechanisms recruit actin into the contractile ring in silkworm spermatocytes. PLoS Biol (2008) 1.00
Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells. J Cell Sci (2010) 0.99
Anillin: a pivotal organizer of the cytokinetic machinery. Biochem Soc Trans (2008) 0.99
Cytokinesis in animal cells. Cold Spring Harb Perspect Biol (2015) 0.99
Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division. Proc Natl Acad Sci U S A (2011) 0.98
Physical model of contractile ring initiation in dividing cells. Biophys J (2007) 0.98
Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol (2010) 0.97
Doubly uniparental inheritance of mitochondria as a model system for studying germ line formation. PLoS One (2011) 0.97
Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex. PLoS One (2013) 0.96
SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Curr Biol (2011) 0.96
The anaphase-promoting complex promotes actomyosin-ring disassembly during cytokinesis in yeast. Mol Biol Cell (2008) 0.96
Incisive imaging and computation for cellular mysteries: lessons from abscission. Cell (2013) 0.95
Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Mol Biol Cell (2009) 0.95
Immobile myosin-II plays a scaffolding role during cytokinesis in budding yeast. J Cell Biol (2013) 0.94
Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis. Proc Natl Acad Sci U S A (2010) 0.94
Crowding of molecular motors determines microtubule depolymerization. Biophys J (2011) 0.93
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol (2005) 11.63
A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A (2008) 10.09
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature (2009) 5.55
Multidimensional drug profiling by automated microscopy. Science (2004) 5.45
Self- and actin-templated assembly of Mammalian septins. Dev Cell (2002) 4.48
A standardized kinesin nomenclature. J Cell Biol (2004) 4.43
Reassembly of contractile actin cortex in cell blebs. J Cell Biol (2006) 4.31
Single-molecule speckle analysis of actin filament turnover in lamellipodia. Science (2002) 4.27
Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell (2004) 3.51
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell (2009) 3.44
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol (2004) 3.39
Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell (2013) 3.26
Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nat Chem Biol (2007) 3.17
Poly(ADP-ribose) is required for spindle assembly and structure. Nature (2004) 3.11
Life and times of a cellular bleb. Biophys J (2007) 3.05
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. J Cell Biol (2003) 3.01
EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules. Mol Biol Cell (2002) 2.92
Determining the position of the cell division plane. Nature (2003) 2.80
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol (2005) 2.70
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation. Mol Biol Cell (2004) 2.51
Structural plasticity in actin and tubulin polymer dynamics. Science (2009) 2.45
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (2011) 2.44
Anillin binds nonmuscle myosin II and regulates the contractile ring. Mol Biol Cell (2004) 2.33
Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton. Chem Biol (2002) 2.28
EB1 targets to kinetochores with attached, polymerizing microtubules. Mol Biol Cell (2002) 2.27
Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Curr Biol (2002) 2.27
Force and length in the mitotic spindle. Curr Biol (2009) 2.11
Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality. Proc Natl Acad Sci U S A (2004) 2.08
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. BMC Biotechnol (2004) 2.08
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1. J Cell Biol (2006) 2.07
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. J Cell Biol (2004) 2.06
A quantitative analysis of contractility in active cytoskeletal protein networks. Biophys J (2008) 2.05
Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Res (2011) 1.99
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds. Nat Rev Drug Discov (2009) 1.95
Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers. J Cell Biol (2008) 1.95
The force-velocity relationship for the actin-based motility of Listeria monocytogenes. Curr Biol (2003) 1.94
Evidence for an upper limit to mitotic spindle length. Curr Biol (2008) 1.94
Cell polarization during monopolar cytokinesis. J Cell Biol (2008) 1.92
Small molecule screening by imaging. Curr Opin Chem Biol (2006) 1.90
Structural insights into yeast septin organization from polarized fluorescence microscopy. Nature (2006) 1.83
Slide-and-cluster models for spindle assembly. Curr Biol (2007) 1.79
An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin. Dev Cell (2003) 1.76
A model for cleavage plane determination in early amphibian and fish embryos. Curr Biol (2010) 1.72
Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Curr Biol (2007) 1.69
A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii. Proc Natl Acad Sci U S A (2004) 1.64
Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex. J Cell Biol (2004) 1.62
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chem Biol (2002) 1.58
XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol (2004) 1.56
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Mol Biol Cell (2011) 1.53
Noble metals strip peptides from class II MHC proteins. Nat Chem Biol (2006) 1.53
Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther (2008) 1.53
KIF4 regulates midzone length during cytokinesis. Curr Biol (2011) 1.51
Midbody assembly and its regulation during cytokinesis. Mol Biol Cell (2012) 1.50
Dynamic stabilization of actin filaments. Proc Natl Acad Sci U S A (2008) 1.50
How does a millimeter-sized cell find its center? Cell Cycle (2009) 1.48
The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. Curr Biol (2002) 1.46
A new method reveals microtubule minus ends throughout the meiotic spindle. J Cell Biol (2006) 1.46
Microtubule plus-end dynamics in Xenopus egg extract spindles. Mol Biol Cell (2004) 1.45
Compression regulates mitotic spindle length by a mechanochemical switch at the poles. Curr Biol (2009) 1.44
Rate-limiting guanosine 5'-triphosphate hydrolysis during nucleotide turnover by FtsZ, a prokaryotic tubulin homologue involved in bacterial cell division. Biochemistry (2004) 1.44
Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor. Chem Biol (2005) 1.43
Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb. Biochemistry (2004) 1.40
High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem (2005) 1.38
Nuf, a Rab11 effector, maintains cytokinetic furrow integrity by promoting local actin polymerization. J Cell Biol (2008) 1.37
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Deformations within moving kinetochores reveal different sites of active and passive force generation. Science (2012) 1.36
The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J Biol Chem (2003) 1.29
Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest. PLoS One (2010) 1.28
Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Cancer Res (2011) 1.27
Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Curr Biol (2009) 1.27
A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes. Curr Biol (2005) 1.26
Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly. Mol Biol Cell (2009) 1.20
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol. BMC Chem Biol (2006) 1.19
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Curr Biol (2009) 1.19
Animal cell hydraulics. J Cell Sci (2009) 1.19
Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Curr Biol (2004) 1.19
Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Mol Cell Proteomics (2009) 1.18
Mammalian septins nomenclature. Mol Biol Cell (2002) 1.16
Clues to CD2-associated protein involvement in cytokinesis. Mol Biol Cell (2005) 1.16
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci (2008) 1.15
Symmetry of septin hourglass and ring structures. J Mol Biol (2007) 1.13
Anticancer flavonoids are mouse-selective STING agonists. ACS Chem Biol (2013) 1.12
Micron-scale coherence in interphase chromatin dynamics. Proc Natl Acad Sci U S A (2013) 1.11
Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament. J Mol Biol (2007) 1.11
Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly. Mol Biol Cell (2009) 1.08
The first World Cell Race. Curr Biol (2012) 1.07
Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos. J Cell Sci (2011) 1.07
Rapid de-localization of actin leading edge components with BDM treatment. BMC Cell Biol (2003) 1.07
Directly probing the mechanical properties of the spindle and its matrix. J Cell Biol (2010) 1.05
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Mol Biol Cell (2012) 1.05
A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Curr Biol (2004) 1.03