Published in J Biol Chem on May 17, 2011
Resurrecting inactive antimicrobial peptides from the lipopolysaccharide trap. Antimicrob Agents Chemother (2014) 0.87
Circular Dichroism studies on the interactions of antimicrobial peptides with bacterial cells. Sci Rep (2014) 0.85
Progressive structuring of a branched antimicrobial peptide on the path to the inner membrane target. J Biol Chem (2012) 0.79
Temporins A and B stimulate migration of HaCaT keratinocytes and kill intracellular Staphylococcus aureus. Antimicrob Agents Chemother (2014) 0.79
Functional divergence in shrimp anti-lipopolysaccharide factors (ALFs): from recognition of cell wall components to antimicrobial activity. PLoS One (2013) 0.79
NMR structure of temporin-1 ta in lipopolysaccharide micelles: mechanistic insight into inactivation by outer membrane. PLoS One (2013) 0.78
β-Boomerang Antimicrobial and Antiendotoxic Peptides: Lipidation and Disulfide Bond Effects on Activity and Structure. Pharmaceuticals (Basel) (2014) 0.76
Temporizin and Temporizin-1 Peptides as Novel Candidates for Eliminating Trypanosoma cruzi. PLoS One (2016) 0.75
Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier. Biochemistry (2016) 0.75
The role of biophysical parameters in the antilipopolysaccharide activities of antimicrobial peptides from marine fish. Mar Drugs (2014) 0.75
Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. Sci Rep (2017) 0.75
Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr (1998) 169.28
The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med (2003) 32.30
AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J Biomol NMR (1996) 29.55
Antimicrobial peptides of multicellular organisms. Nature (2002) 23.50
Lipopolysaccharide endotoxins. Annu Rev Biochem (2001) 18.88
Torsion angle dynamics for NMR structure calculation with the new program DYANA. J Mol Biol (1997) 15.40
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol (2005) 13.69
Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev (2003) 13.49
The immunopathogenesis of sepsis. Nature (2002) 11.83
Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science (1994) 11.18
Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol (2003) 11.11
Peptide antibiotics and their role in innate immunity. Annu Rev Immunol (1995) 6.81
Biochemistry of endotoxins. Annu Rev Biochem (1990) 6.75
Mechanisms of antimicrobial peptide action and resistance. Pharmacol Rev (2003) 6.57
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta (1999) 5.85
The bacteria fight back. Science (2008) 5.76
Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature (1981) 5.66
LPS, TLR4 and infectious disease diversity. Nat Rev Microbiol (2005) 5.25
Epidemiology of sepsis: an update. Crit Care Med (2001) 5.16
Mode of action of membrane active antimicrobial peptides. Biopolymers (2002) 4.74
Diversity of antimicrobial peptides and their mechanisms of action. Biochim Biophys Acta (1999) 4.71
Protein NMR recall, precision, and F-measure scores (RPF scores): structure quality assessment measures based on information retrieval statistics. J Am Chem Soc (2005) 4.43
Alterations in outer membrane permeability. Annu Rev Microbiol (1984) 4.22
Amphipathic, alpha-helical antimicrobial peptides. Biopolymers (2000) 3.68
The role of antimicrobial peptides in animal defenses. Proc Natl Acad Sci U S A (2000) 3.52
Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor. J Am Chem Soc (2001) 3.47
NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors. Angew Chem Int Ed Engl (2003) 2.98
Anti-microbial peptides: from invertebrates to vertebrates. Immunol Rev (2004) 2.80
The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. Biochim Biophys Acta (1999) 2.79
Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta (2008) 2.73
Cationic host defense (antimicrobial) peptides. Curr Opin Immunol (2005) 2.71
Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells. Biochim Biophys Acta (1999) 2.41
Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J Biol Chem (1995) 2.02
Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge. Anal Biochem (1984) 1.93
Glycophorin A helical transmembrane domains dimerize in phospholipid bilayers: a resonance energy transfer study. Biochemistry (1994) 1.87
Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics. Emerg Infect Dis (2001) 1.74
Structure and metal-binding properties of lipopolysaccharides from heptoseless mutants of Escherichia coli studied by 13C and 31P nuclear magnetic resonance. J Biol Chem (1983) 1.44
Host defence peptides from invertebrates--emerging antimicrobial strategies. Immunobiology (2006) 1.33
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. Biochim Biophys Acta (2008) 1.31
Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochim Biophys Acta (2006) 1.29
Temporins, antimicrobial peptides from the European red frog Rana temporaria. Eur J Biochem (1996) 1.29
Exchange-transferred NOE spectroscopy and bound ligand structure determination. Curr Opin Struct Biol (2003) 1.27
The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. Biochemistry (2000) 1.21
A synergism between temporins toward Gram-negative bacteria overcomes resistance imposed by the lipopolysaccharide protective layer. J Biol Chem (2006) 1.06
NMR structure of pardaxin, a pore-forming antimicrobial peptide, in lipopolysaccharide micelles: mechanism of outer membrane permeabilization. J Biol Chem (2009) 1.05
Helical hairpin structure of a potent antimicrobial peptide MSI-594 in lipopolysaccharide micelles by NMR spectroscopy. Chemistry (2009) 1.04
Binding of the antimicrobial peptide temporin L to liposomes assessed by Trp fluorescence. J Biol Chem (2002) 1.02
Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J Biol Chem (2005) 1.01
The search for molecular determinants of LPS inhibition by proteins and peptides. Curr Top Med Chem (2004) 1.01
Solution NMR studies of amphibian antimicrobial peptides: linking structure to function? Biochim Biophys Acta (2009) 1.01
Lipopolysaccharide, a key molecule involved in the synergism between temporins in inhibiting bacterial growth and in endotoxin neutralization. J Biol Chem (2008) 0.99
Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides. FEBS J (2009) 0.99
Interactions of the antimicrobial peptides temporins with model biomembranes. Comparison of temporins B and L. Biochemistry (2002) 0.98
NMR experiments reveal the molecular basis of receptor recognition by a calicivirus. J Am Chem Soc (2008) 0.97
Multifunctional host defense peptides: antiparasitic activities. FEBS J (2009) 0.96
De novo designed lipopolysaccharide binding peptides: structure based development of antiendotoxic and antimicrobial drugs. Curr Med Chem (2010) 0.95
Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis. Biochemistry (2003) 0.95
Endotoxin neutralizing peptides. Curr Top Med Chem (2004) 0.94
Designed beta-boomerang antiendotoxic and antimicrobial peptides: structures and activities in lipopolysaccharide. J Biol Chem (2009) 0.94
Temporins, anti-infective peptides with expanding properties. Cell Mol Life Sci (2006) 0.93
Evidence for assembly of small multidrug resistance proteins by a "two-faced" transmembrane helix. J Biol Chem (2006) 0.90
High-resolution solution structure of a designed peptide bound to lipopolysaccharide: transferred nuclear Overhauser effects, micelle selectivity, and anti-endotoxic activity. Biochemistry (2007) 0.90
Temporins and their synergism against Gram-negative bacteria and in lipopolysaccharide detoxification. Biochim Biophys Acta (2009) 0.90
31P N.m.r. evidence for the presence of triphosphate residues in lipopolysaccharides from Pseudomonas aeruginosa. Biochem J (1981) 0.90
Antiviral effects of synthetic membrane-active peptides on herpes simplex virus, type 1. Int J Antimicrob Agents (1999) 0.89
Molecular recognition of sialyl Lewis(x) and related saccharides by two lectins. J Am Chem Soc (2001) 0.88
A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L. J Med Chem (2008) 0.87
Structural and thermodynamic analyses of the interaction between melittin and lipopolysaccharide. Biochim Biophys Acta (2007) 0.86
Interaction of antimicrobial peptide temporin L with lipopolysaccharide in vitro and in experimental rat models of septic shock caused by gram-negative bacteria. Antimicrob Agents Chemother (2006) 0.86
Mapping residue-specific contacts of polymyxin B with lipopolysaccharide by saturation transfer difference NMR: insights into outer-membrane disruption and endotoxin neutralization. Biopolymers (2011) 0.80
Biological characterization and modes of action of temporins and bombinins H, multiple forms of short and mildly cationic anti-microbial peptides from amphibian skin. J Pept Sci (2007) 0.80
Model of a putative pore: the pentameric alpha-helical bundle of SARS coronavirus E protein in lipid bilayers. Biophys J (2006) 1.13
NMR structure of pardaxin, a pore-forming antimicrobial peptide, in lipopolysaccharide micelles: mechanism of outer membrane permeabilization. J Biol Chem (2009) 1.05
Helical hairpin structure of a potent antimicrobial peptide MSI-594 in lipopolysaccharide micelles by NMR spectroscopy. Chemistry (2009) 1.04
Applications of saturation transfer difference NMR in biological systems. Drug Discov Today (2011) 0.98
Structure, interactions, and antibacterial activities of MSI-594 derived mutant peptide MSI-594F5A in lipopolysaccharide micelles: role of the helical hairpin conformation in outer-membrane permeabilization. J Am Chem Soc (2010) 0.98
NMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tails. J Biol Chem (2008) 0.95
Designed beta-boomerang antiendotoxic and antimicrobial peptides: structures and activities in lipopolysaccharide. J Biol Chem (2009) 0.94
Lipopolysaccharide neutralizing peptide-porphyrin conjugates for effective photoinactivation and intracellular imaging of gram-negative bacteria strains. Bioconjug Chem (2012) 0.89
Resurrecting inactive antimicrobial peptides from the lipopolysaccharide trap. Antimicrob Agents Chemother (2014) 0.87
Structural and thermodynamic analyses of the interaction between melittin and lipopolysaccharide. Biochim Biophys Acta (2007) 0.86
NMR structural studies of the Ste11 SAM domain in the dodecyl phosphocholine micelle. Proteins (2009) 0.84
Structures and interaction analyses of integrin αMβ2 cytoplasmic tails. J Biol Chem (2011) 0.84
NMR structure of integrin α4 cytosolic tail and its interactions with paxillin. PLoS One (2013) 0.81
Structure, activity and interactions of the cysteine deleted analog of tachyplesin-1 with lipopolysaccharide micelle: Mechanistic insights into outer-membrane permeabilization and endotoxin neutralization. Biochim Biophys Acta (2012) 0.81
Immobilization studies of an engineered arginine-tryptophan-rich peptide on a silicone surface with antimicrobial and antibiofilm activity. ACS Appl Mater Interfaces (2013) 0.80
Structure and binding interface of the cytosolic tails of αXβ2 integrin. PLoS One (2012) 0.80
Mapping residue-specific contacts of polymyxin B with lipopolysaccharide by saturation transfer difference NMR: insights into outer-membrane disruption and endotoxin neutralization. Biopolymers (2011) 0.80
Interactions of a designed peptide with lipopolysaccharide: Bound conformation and anti-endotoxic activity. Biochem Biophys Res Commun (2008) 0.80
Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties. Acta Biomater (2013) 0.79
β-Hairpin peptides: heme binding, catalysis, and structure in detergent micelles. Angew Chem Int Ed Engl (2013) 0.79
Oligomeric structure of a cathelicidin antimicrobial peptide in dodecylphosphocholine micelle determined by NMR spectroscopy. Biochim Biophys Acta (2010) 0.79
Peptide-perylene diimide functionalized magnetic nano-platforms for fluorescence turn-on detection and clearance of bacterial lipopolysaccharides. Chem Commun (Camb) (2014) 0.79
NMR structure of temporin-1 ta in lipopolysaccharide micelles: mechanistic insight into inactivation by outer membrane. PLoS One (2013) 0.78
An integrated analysis of the effects of Esculentin 1-21 on Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 0.77
Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility. Biotechnol Bioeng (2013) 0.77
Toward an improved structural model of the frog-skin antimicrobial peptide esculentin-1b(1-18). Biopolymers (2012) 0.77
Designed di-heme binding helical transmembrane protein. Chembiochem (2014) 0.77
Structural determinants of the specificity of a membrane binding domain of the scaffold protein Ste5 of budding yeast: implications in signaling by the scaffold protein in MAPK pathway. Biochim Biophys Acta (2012) 0.76
Functional and structural characterization of the talin F0F1 domain. Biochem Biophys Res Commun (2009) 0.76
NMR structure, localization, and vesicle fusion of Chikungunya virus fusion peptide. Biochemistry (2012) 0.76
Micelle-bound structures and dynamics of the hinge deleted analog of melittin and its diastereomer: implications in cell selective lysis by D-amino acid containing antimicrobial peptides. Biochim Biophys Acta (2009) 0.75
Equilibrium unfolding of the dimeric SAM domain of MAPKKK Ste11 from the budding yeast: role of the interfacial residues in structural stability and binding. Biochemistry (2007) 0.75
Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multi-Drug Resistant Bacteria. ACS Appl Mater Interfaces (2017) 0.75
Characterization of the near native conformational states of the SAM domain of Ste11 protein by NMR spectroscopy. Proteins (2014) 0.75